{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T20:00:37Z","timestamp":1789416037524,"version":"build-2803163510"},"reference-count":32,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"vor","delay-in-days":730,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jvascsurg.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Vascular Surgery"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1016\/j.jvs.2021.05.052","type":"journal-article","created":{"date-parts":[[2021,6,26]],"date-time":"2021-06-26T03:22:07Z","timestamp":1624677727000},"page":"2014-2022.e4","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"title":["Arterial stiffness predicts amputation and death in patients with chronic limb-threatening ischemia"],"prefix":"10.1016","volume":"74","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7366-6685","authenticated-orcid":false,"given":"Daniel","family":"Mendes-Pinto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria da Gloria","family":"Rodrigues-Machado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo Laranjo","family":"Avelar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T\u00falio Pinho","family":"Navarro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Dardik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jvs.2021.05.052_bib1","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.atherosclerosis.2015.05.007","volume":"241","author":"Vlachopoulos","year":"2015","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.jvs.2021.05.052_bib2","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1161\/ATVBAHA.120.313128","article-title":"Central versus peripheral artery stiffening and cardiovascular risk","volume":"40","author":"Yu","year":"2020","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jvs.2021.05.052_bib3","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1093\/eurheartj\/eht151","article-title":"2013 ESH\/ESC guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC)","volume":"34","author":"Mancia","year":"2013","journal-title":"Eur Heart J"},{"key":"10.1016\/j.jvs.2021.05.052_bib4","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1161\/HYP.0000000000000033","article-title":"American Heart Association Council on Hypertension. Recommendations for improving and standardizing vascular research on arterial stiffness: a scientific statement from the American Heart Association","volume":"66","author":"Townsend","year":"2015","journal-title":"Hypertension"},{"key":"10.1016\/j.jvs.2021.05.052_bib5","first-page":"e20180073","article-title":"Association between critical limb ischemia and arterial stiffness measured by brachial artery oscillometry","volume":"18","author":"Mendes-Pinto","year":"2019","journal-title":"J\u00a0Vasc Bras"},{"key":"10.1016\/j.jvs.2021.05.052_bib6","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.avsg.2019.07.017","article-title":"Association between critical limb ischemia, the Society for Vascular Surgery Wound, Ischemia and Foot Infection (WIfI) classification system and arterial stiffness","volume":"63","author":"Mendes-Pinto","year":"2020","journal-title":"Ann Vasc Surg"},{"key":"10.1016\/j.jvs.2021.05.052_bib7","first-page":"145","article-title":"Tonometric and oscillometric methods for measurement of central blood pressure parameters: a comparison in patients with borderline hypertension or stage 1 hypertension","volume":"33","author":"Barroso","year":"2020","journal-title":"Int J Cardiovasc Sci"},{"key":"10.1016\/j.jvs.2021.05.052_bib8","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.ejvs.2013.06.005","article-title":"A\u00a0mismatch between aortic pulse pressure and pulse wave velocity predicts advanced peripheral arterial disease","volume":"46","author":"Brand","year":"2013","journal-title":"Eur J Vasc Endovasc Surg"},{"issue":"Suppl S","key":"10.1016\/j.jvs.2021.05.052_bib9","doi-asserted-by":"crossref","first-page":"S5","DOI":"10.1016\/j.jvs.2006.12.037","article-title":"inter-society consensus for the management of peripheral arterial disease (TASC II)","volume":"45","author":"Norgren","year":"2007","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2021.05.052_bib10","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1097\/MBP.0b013e328353ff63","article-title":"Oscillometric estimation of central blood pressure: validation of the Mobil-O-Graph in comparison with the SphygmoCor device","volume":"17","author":"Weiss","year":"2012","journal-title":"Blood Press Monit"},{"key":"10.1016\/j.jvs.2021.05.052_bib11","first-page":"e686","article-title":"2016 AHA\/ACC Guideline on the Management of Patients With Lower Extremity Peripheral Artery Disease: Executive Summary: A Report of the American College of Cardiology\/American Heart Association Task Force on Clinical Practice Guidelines","volume":"135","author":"Gerhard-Herman","year":"2017","journal-title":"Circulation"},{"key":"10.1016\/j.jvs.2021.05.052_bib12","doi-asserted-by":"crossref","first-page":"3S","DOI":"10.1016\/j.jvs.2019.02.016","article-title":"Global vascular guidelines on the management of chronic limb-threatening ischemia","volume":"69","author":"Conte","year":"2019","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2021.05.052_bib13","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.jss.2017.11.062","article-title":"Characterizing the relationship between flow-mediated vasodilation and radial artery tonometry in peripheral artery disease","volume":"224","author":"Zahner","year":"2018","journal-title":"J\u00a0Surg Res"},{"key":"10.1016\/j.jvs.2021.05.052_bib14","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1111\/jch.12167","article-title":"Increased aortic stiffness and related factors in patients with peripheral arterial disease","volume":"15","author":"Catalano","year":"2013","journal-title":"J\u00a0Clin Hypertens"},{"key":"10.1016\/j.jvs.2021.05.052_bib15","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1111\/jch.12406","article-title":"Aortic augmentation index in patients with peripheral arterial disease","volume":"16","author":"Catalano","year":"2014","journal-title":"J\u00a0Clin Hypertens (Greenwich)"},{"key":"10.1016\/j.jvs.2021.05.052_bib16","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1016\/j.jacc.2013.09.063","article-title":"Aortic pulse wave velocity improves cardiovascular event prediction: an individual participant meta-analysis of prospective observational data from 17,635 subjects","volume":"63","author":"Ben-Shlomo","year":"2014","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.jvs.2021.05.052_bib17","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1177\/0003319717742544","article-title":"Carotid\u2013femoral pulse wave velocity in the prediction of cardiovascular events and mortality: an updated systematic review and meta-analysis","volume":"69","author":"Zhong","year":"2018","journal-title":"Angiology"},{"key":"10.1016\/j.jvs.2021.05.052_bib18","doi-asserted-by":"crossref","first-page":"2338","DOI":"10.1093\/eurheartj\/ehq165","article-title":"Determinants of pulse wave velocity in healthy people and in the presence of cardiovascular risk factors: \u2018establishing normal and reference values","volume":"31","year":"2010","journal-title":"Eur Hear J"},{"key":"10.1016\/j.jvs.2021.05.052_bib19","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1253\/circj.CJ-17-0636","article-title":"Collaborative Group for Japan Brachial-Ankle pulse wave VELocity individual participant data meta-analysis of prospective studies (J-BAVEL). Proposed cutoff value of brachial-ankle pulse wave velocity for the management of hypertension","volume":"81","author":"Ohkuma","year":"2017","journal-title":"Circ J"},{"key":"10.1016\/j.jvs.2021.05.052_bib20","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/s13239-019-00439-w","article-title":"Cardiac output monitoring in children, adolescents and adults based on pulse contour analysis: comparison with echocardiography-derived data and identification of factors associated with their differences","volume":"11","author":"Z\u00f3calo","year":"2020","journal-title":"Cardiovasc Eng Technol"},{"key":"10.1016\/j.jvs.2021.05.052_bib21","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1186\/s12872-016-0389-x","article-title":"Association between novel arterial stiffness indices and risk factors of cardiovascular disease","volume":"16","author":"Okamoto","year":"2016","journal-title":"BMC Cardiovasc Disord"},{"key":"10.1016\/j.jvs.2021.05.052_bib22","doi-asserted-by":"crossref","first-page":"7457385","DOI":"10.1155\/2019\/7457385","article-title":"Gender difference of the relationship between arterial stiffness and blood pressure variability in participants in prehypertension","volume":"2019","author":"Lan","year":"2019","journal-title":"Int J Hypertens"},{"key":"10.1016\/j.jvs.2021.05.052_bib23","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1159\/000365267","article-title":"Gender difference in arterial stiffness in a multicenter cross-sectional study: the Korean Arterial Aging Study (KAAS)","volume":"2","author":"Kim","year":"2014","journal-title":"Pulse (Basel)"},{"issue":"Suppl","key":"10.1016\/j.jvs.2021.05.052_bib24","doi-asserted-by":"crossref","first-page":"18S","DOI":"10.1016\/j.jvs.2012.10.115","article-title":"Peripheral arterial disease in women","volume":"57","author":"Teodorescu","year":"2013","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2021.05.052_bib25","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1161\/ATVBAHA.120.313133","article-title":"Ethnicity and arterial stiffness","volume":"40","author":"Schutte","year":"2020","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jvs.2021.05.052_bib26","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1161\/HYPERTENSIONAHA.115.06066","article-title":"Association of central versus brachial blood pressure with target-organ damage: systematic review and meta-analysis","volume":"67","author":"Kollias","year":"2016","journal-title":"Hypertension"},{"key":"10.1016\/j.jvs.2021.05.052_bib27","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1080\/10641963.2018.1557682","article-title":"Central aortic pressure improves prediction of cardiovascular events compared to peripheral blood pressure in short-term follow-up of a hypertensive cohort","volume":"42","author":"Zuo","year":"2020","journal-title":"Clin Exp Hypertens"},{"key":"10.1016\/j.jvs.2021.05.052_bib28","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1161\/01.HYP.0000165025.16381.44","article-title":"Aortic pressure augmentation predicts adverse cardiovascular events in patients with established coronary artery disease","volume":"45","author":"Chirinos","year":"2005","journal-title":"Hypertension"},{"key":"10.1016\/j.jvs.2021.05.052_bib29","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1016\/j.jvs.2014.11.045","article-title":"The Society for Vascular Surgery lower extremity threatened limb classification system based on Wound, Ischemia, and foot Infection (WIfI) correlates with risk of major amputation and time to wound healing","volume":"61","author":"Zhan","year":"2015","journal-title":"J\u00a0Vasc Surg"},{"key":"10.1016\/j.jvs.2021.05.052_bib30","doi-asserted-by":"crossref","first-page":"2628","DOI":"10.1161\/CIRCULATIONAHA.106.667733","article-title":"Cross-sectional correlates of increased aortic stiffness in the community: the Framingham Heart Study","volume":"115","author":"Mitchell","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.jvs.2021.05.052_bib31","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1159\/000484442","article-title":"Evaluation of central blood pressure in an Asian population: comparison between brachial oscillometry and radial tonometry methods","volume":"6","author":"Hoshide","year":"2018","journal-title":"Pulse (Basel)"},{"key":"10.1016\/j.jvs.2021.05.052_bib32","doi-asserted-by":"crossref","first-page":"e0226709","DOI":"10.1371\/journal.pone.0226709","article-title":"Aortic pressure and forward and backward wave components in children, adolescents and young-adults: agreement between brachial oscillometry, radial and carotid tonometry data and analysis of factors associated with their differences","volume":"14","author":"Zinoveev","year":"2019","journal-title":"PLoS One"}],"container-title":["Journal of Vascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0741521421010053?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0741521421010053?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T20:34:24Z","timestamp":1760042064000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0741521421010053"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":32,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["S0741521421010053"],"URL":"https:\/\/doi.org\/10.1016\/j.jvs.2021.05.052","relation":{},"ISSN":["0741-5214"],"issn-type":[{"value":"0741-5214","type":"print"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Arterial stiffness predicts amputation and death in patients with chronic limb-threatening ischemia","name":"articletitle","label":"Article Title"},{"value":"Journal of Vascular Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jvs.2021.05.052","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Published by Elsevier Inc. on behalf of the Society for Vascular Surgery.","name":"copyright","label":"Copyright"}]}}