{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T00:00:34Z","timestamp":1784764834163,"version":"3.55.0"},"reference-count":121,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jvascsurg.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Vascular Surgery"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.jvs.2026.04.032","type":"journal-article","created":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T07:00:05Z","timestamp":1778137205000},"page":"351-362.e6","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["A systematic review and meta-analysis of cancer risk in patients with abdominal aortic aneurysm"],"prefix":"10.1016","volume":"84","author":[{"given":"Zhixiong","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi","family":"Shu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huanrui","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jichun","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vidalack","family":"Vilayphone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjie","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yazhou","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6197-1527","authenticated-orcid":false,"given":"Yi","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jvs.2026.04.032_bib1","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1097\/SLA.0000000000005716","article-title":"The global and regional prevalence of abdominal aortic aneurysms: a systematic review and modeling analysis","volume":"277","author":"Song","year":"2023","journal-title":"Ann Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib2","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1186\/s13045-024-01640-8","article-title":"Global burden of cancer and associated risk factors in 204 countries and territories, 1980-2021: a systematic analysis for the GBD 2021","volume":"17","author":"Wu","year":"2024","journal-title":"J Hematol Oncol"},{"key":"10.1016\/j.jvs.2026.04.032_bib3","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1161\/ATVBAHA.124.319863","article-title":"Cardiovascular disease and cancer: a dangerous liaison","volume":"45","author":"Newman","year":"2025","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jvs.2026.04.032_bib4","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.jaccao.2023.01.010","article-title":"Risk of cancer after diagnosis of cardiovascular disease","volume":"5","author":"Bell","year":"2023","journal-title":"JACC CardioOncology"},{"key":"10.1016\/j.jvs.2026.04.032_bib5","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1186\/s12916-025-04013-1","article-title":"Cancer risk subsequent to cardiovascular disease: a prospective population-based study and meta-analysis","volume":"23","author":"Shu","year":"2025","journal-title":"BMC Med"},{"key":"10.1016\/j.jvs.2026.04.032_bib6","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1038\/s41569-024-01017-x","article-title":"Cardiovascular disease and cancer: shared risk factors and mechanisms","volume":"21","author":"Wilcox","year":"2024","journal-title":"Nat Rev Cardiol"},{"key":"10.1016\/j.jvs.2026.04.032_bib7","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.ejvs.2022.07.007","article-title":"Radiation and chemotherapy are associated with altered aortic aneurysm growth in patients with cancer: impact of synchronous cancer and aortic aneurysm","volume":"64","author":"Becker von Rose","year":"2022","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib8","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1016\/S0140-6736(05)66459-8","article-title":"Abdominal aortic aneurysm","volume":"365","author":"Sakalihasan","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.jvs.2026.04.032_bib9","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.freeradbiomed.2023.12.018","article-title":"TNF-\u03b1 induced NF-\u03baB mediated LYRM7 expression modulates the tumor growth and metastatic ability in breast cancer","volume":"211","author":"Shinde","year":"2024","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.jvs.2026.04.032_bib10","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1038\/nature01322","article-title":"Inflammation and cancer","volume":"420","author":"Coussens","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.jvs.2026.04.032_bib11","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1186\/s12943-023-01744-8","article-title":"Extracellular matrix remodeling in tumor progression and immune escape: from mechanisms to treatments","volume":"22","author":"Yuan","year":"2023","journal-title":"Mol Cancer"},{"key":"10.1016\/j.jvs.2026.04.032_bib12","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1016\/j.jclinepi.2009.06.005","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"62","author":"Moher","year":"2009","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.jvs.2026.04.032_bib13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/oxfordjournals.epirev.a036298","article-title":"Quantitative methods in the review of epidemiologic literature","volume":"9","author":"Greenland","year":"1987","journal-title":"Epidemiol Rev"},{"key":"10.1016\/j.jvs.2026.04.032_bib14","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1093\/oxfordjournals.aje.a114593","article-title":"Interpretation and choice of effect measures in epidemiologic analyses","volume":"125","author":"Greenland","year":"1987","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.jvs.2026.04.032_bib15","author":"Wells"},{"key":"10.1016\/j.jvs.2026.04.032_bib16","doi-asserted-by":"crossref","first-page":"820","DOI":"10.7326\/0003-4819-127-9-199711010-00008","article-title":"Quantitative synthesis in systematic reviews","volume":"127","author":"Lau","year":"1997","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.jvs.2026.04.032_bib18","doi-asserted-by":"crossref","first-page":"4137","DOI":"10.21873\/anticanres.14413","article-title":"Coprevalence and incidence of lung cancer in patients screened for abdominal aortic aneurysm","volume":"40","author":"Hohneck","year":"2020","journal-title":"Anticancer Res"},{"issue":"Suppl","key":"10.1016\/j.jvs.2026.04.032_bib19","article-title":"Influence of unruptured abdominal aortic aneurysm (AAA) diagnosis on risk of malignant neoplasms in patients with obesity and ischemic heart disease","volume":"43","author":"Olojakpoke","year":"2025","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.jvs.2026.04.032_bib20","doi-asserted-by":"crossref","first-page":"1776","DOI":"10.1016\/j.jvs.2018.09.058","article-title":"A population-based cohort study examining the risk of abdominal cancer after endovascular abdominal aortic aneurysm repair","volume":"69","author":"Markar","year":"2019","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib21","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/S0039-6060(98)70262-4","article-title":"Abdominal aortic aneurysms and malignant neoplasia: double jeopardy","volume":"123","author":"Valentine","year":"1998","journal-title":"Surgery"},{"key":"10.1016\/j.jvs.2026.04.032_bib22","doi-asserted-by":"crossref","first-page":"1694","DOI":"10.1161\/ATVBAHA.123.320543","article-title":"Cancer incidence after diagnosis of abdominal aortic aneurysm-brief report","volume":"44","author":"Luo","year":"2024","journal-title":"Arterioscler, Thromb Vasc Biol"},{"key":"10.1016\/j.jvs.2026.04.032_bib23","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1111\/j.1749-6632.1996.tb33299.x","article-title":"Incidence of cancer and abdominal aortic aneurysms. A logistic regression analysis","volume":"800","author":"Chan","year":"1996","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.jvs.2026.04.032_bib24","doi-asserted-by":"crossref","first-page":"2829","DOI":"10.18632\/oncotarget.20181","article-title":"Increased risk of malignancy in patients with an aortic aneurysm: a nationwide population-based retrospective study","volume":"9","author":"Wang","year":"2018","journal-title":"Oncotarget"},{"key":"10.1016\/j.jvs.2026.04.032_bib25","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.avsg.2018.08.095","article-title":"Late-onset malignant neoplasms and their prognostic factors after abdominal aortic aneurysm repair","volume":"56","author":"Onohara","year":"2019","journal-title":"Ann Vasc Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib26","doi-asserted-by":"crossref","first-page":"3691","DOI":"10.1007\/s00423-022-02670-x","article-title":"Long-term outcome and cancer incidence after abdominal aortic aneurysm repair","volume":"407","author":"Ettengruber","year":"2022","journal-title":"Langenbecks Arch Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib27","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.jvs.2022.03.896","article-title":"Risk of various cancers in adults with abdominal aortic aneurysms","volume":"77","author":"Cho","year":"2023","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib28","doi-asserted-by":"crossref","first-page":"3847","DOI":"10.3390\/jcm10173847","article-title":"The prevalence of concomitant abdominal aortic aneurysm and cancer","volume":"10","author":"Kim","year":"2021","journal-title":"J Clin Med"},{"key":"10.1016\/j.jvs.2026.04.032_bib29","doi-asserted-by":"crossref","first-page":"6934","DOI":"10.3390\/jcm13226934","article-title":"Sex differences in long-term survival and cancer incidence after ruptured abdominal aortic aneurysm repair","volume":"13","author":"Epple","year":"2024","journal-title":"J Clin Med"},{"key":"10.1016\/j.jvs.2026.04.032_bib30","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.jtho.2023.09.004","article-title":"Bidirectional association between cardiovascular disease and lung cancer in a prospective cohort Study","volume":"19","author":"Zhang","year":"2024","journal-title":"J Thorac Oncol"},{"key":"10.1016\/j.jvs.2026.04.032_bib31","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/j.ajcnut.2024.07.033","article-title":"Cardiovascular health, polygenic risk score, and cancer risk: a prospective cohort study","volume":"120","author":"Peng","year":"2024","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.jvs.2026.04.032_bib32","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1097\/JTO.0000000000000180","article-title":"Self-reported cardiovascular disease and the risk of lung cancer, the HUNT study","volume":"9","author":"Hatlen","year":"2014","journal-title":"J Thorac Oncol"},{"key":"10.1016\/j.jvs.2026.04.032_bib33","doi-asserted-by":"crossref","first-page":"4232","DOI":"10.3390\/ijms25084232","article-title":"Atherosclerosis and the bidirectional relationship between cancer and cardiovascular disease: from bench to bedside-part 1","volume":"25","author":"Gallucci","year":"2024","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jvs.2026.04.032_bib34","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1038\/s41569-022-00698-6","article-title":"Cardio-onco-metabolism: metabolic remodelling in cardiovascular disease and cancer","volume":"19","author":"Karlstaedt","year":"2022","journal-title":"Nat Rev Cardiol"},{"key":"10.1016\/j.jvs.2026.04.032_bib35","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.jaccao.2022.01.100","article-title":"Incident cardiovascular disease among adults with cancer: a population-based cohort study","volume":"4","author":"Paterson","year":"2022","journal-title":"JACC CardioOncology"},{"key":"10.1016\/j.jvs.2026.04.032_bib36","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.118.009543","article-title":"Atrial fibrillation and risk of cancer: a Danish population-based cohort study","volume":"7","author":"Vinter","year":"2018","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.jvs.2026.04.032_bib37","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1093\/eurjpc\/zwab084","article-title":"Association of premature atherosclerotic cardiovascular disease with higher risk of cancer: a behavioral risk factor surveillance system study","volume":"29","author":"Jain","year":"2022","journal-title":"Eur J Prev Cardiol"},{"key":"10.1016\/j.jvs.2026.04.032_bib38","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1001\/archsurg.1967.01330150078012","article-title":"Coincidental malignancy and abdominal aortic aneurysm. Problems of management","volume":"95","author":"Szilagyi","year":"1967","journal-title":"Arch Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib39","doi-asserted-by":"crossref","first-page":"5652","DOI":"10.1038\/s41467-024-49921-7","article-title":"Abdominal aortic aneurysm and cardiometabolic traits share strong genetic susceptibility to lipid metabolism and inflammation","volume":"15","author":"Zheng","year":"2024","journal-title":"Nat Commun"},{"key":"10.1016\/j.jvs.2026.04.032_bib40","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.a2467","article-title":"Incidence of cardiovascular disease and cancer in advanced age: prospective cohort study","volume":"337","author":"Driver","year":"2008","journal-title":"BMJ"},{"key":"10.1016\/j.jvs.2026.04.032_bib41","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1016\/j.bbrc.2004.08.129","article-title":"Cigarette suppresses the expression of P4Halpha and vascular collagen production","volume":"323","author":"Raveendran","year":"2004","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.jvs.2026.04.032_bib42","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1016\/j.jvs.2007.01.058","article-title":"Cigarette smoking increases aortic dilatation without affecting matrix metalloproteinase-9 and -12 expression in a modified mouse model of aneurysm formation","volume":"45","author":"Bergoeing","year":"2007","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib43","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1002\/ijc.23894","article-title":"Nicotine induces cell proliferation, invasion and epithelial-mesenchymal transition in a variety of human cancer cell lines","volume":"124","author":"Dasgupta","year":"2009","journal-title":"Int J Cancer"},{"key":"10.1016\/j.jvs.2026.04.032_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2022.115344","article-title":"Transcription factor SP1 and oncoprotein PPP1R13L regulate nicotine-induced epithelial-mesenchymal transition in lung adenocarcinoma via a feedback loop","volume":"206","author":"Zhang","year":"2022","journal-title":"Biochem Pharmacol"},{"key":"10.1016\/j.jvs.2026.04.032_bib45","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1038\/nrc3725","article-title":"Connections of nicotine to cancer","volume":"14","author":"Grando","year":"2014","journal-title":"Nat Rev Cancer"},{"key":"10.1016\/j.jvs.2026.04.032_bib46","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1186\/s12943-024-02020-z","article-title":"Aging and cancer","volume":"23","author":"Mont\u00e9gut","year":"2024","journal-title":"Mol Cancer"},{"key":"10.1016\/j.jvs.2026.04.032_bib47","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1056\/NEJMra0804615","article-title":"DNA damage, aging, and cancer","volume":"361","author":"Hoeijmakers","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jvs.2026.04.032_bib48","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1038\/s41580-024-00727-x","article-title":"The senescence-associated secretory phenotype and its physiological and pathological implications","volume":"25","author":"Wang","year":"2024","journal-title":"Nat Rev Mol Cell Biol"},{"key":"10.1016\/j.jvs.2026.04.032_bib49","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.1172\/JCI8931","article-title":"Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms","volume":"105","author":"Pyo","year":"2000","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jvs.2026.04.032_bib50","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1161\/01.CIR.104.3.304","article-title":"Ubiquitous elevation of matrix metalloproteinase-2 expression in the vasculature of patients with abdominal aneurysms","volume":"104","author":"Goodall","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.jvs.2026.04.032_bib51","doi-asserted-by":"crossref","first-page":"3028","DOI":"10.3390\/ijms19103028","article-title":"Role of extracellular matrix in development and cancer progression","volume":"19","author":"Walker","year":"2018","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.jvs.2026.04.032_bib52","doi-asserted-by":"crossref","first-page":"7249","DOI":"10.1038\/s41467-024-51030-4","article-title":"Macrophage ILF3 promotes abdominal aortic aneurysm by inducing inflammatory imbalance in male mice","volume":"15","author":"Wang","year":"2024","journal-title":"Nat Commun"},{"key":"10.1016\/j.jvs.2026.04.032_bib53","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.989933","article-title":"Immune and inflammatory mechanisms of abdominal aortic aneurysm","volume":"13","author":"M\u00e1rquez-S\u00e1nchez","year":"2022","journal-title":"Front Immunol"},{"key":"10.1016\/j.jvs.2026.04.032_bib54","doi-asserted-by":"crossref","first-page":"2260","DOI":"10.1161\/01.CIR.103.18.2260","article-title":"Interleukin-6 (IL-6) and the prognosis of abdominal aortic aneurysms","volume":"103","author":"Jones","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.jvs.2026.04.032_bib55","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1172\/JCI0215334","article-title":"Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms","volume":"110","author":"Longo","year":"2002","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jvs.2026.04.032_bib56","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.cell.2010.03.015","article-title":"Matrix metalloproteinases: regulators of the tumor microenvironment","volume":"141","author":"Kessenbrock","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.jvs.2026.04.032_bib57","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1186\/s12929-017-0400-6","article-title":"Id-1 promotes migration and invasion of non-small cell lung cancer cells through activating NF-\u03baB signaling pathway","volume":"24","author":"Li","year":"2017","journal-title":"J Biomed Sci"},{"issue":"2","key":"10.1016\/j.jvs.2026.04.032_bib58","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1002\/ptr.7358","article-title":"Eugenol restrains abdominal aortic aneurysm progression with down-regulations on NF-\u03baB and COX-2","volume":"36","author":"Zhai","year":"2022","journal-title":"Phytother Res"},{"key":"10.1016\/j.jvs.2026.04.032_bib59","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1038\/nrc3627","article-title":"VEGF targets the tumour cell","volume":"13","author":"Goel","year":"2013","journal-title":"Nat Rev Cancer"},{"key":"10.1016\/j.jvs.2026.04.032_bib60","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2023.175586","article-title":"The role of VEGF in cancer-induced angiogenesis and research progress of drugs targeting VEGF","volume":"949","author":"Ghalehbandi","year":"2023","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.jvs.2026.04.032_bib61","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.cell.2024.11.009","article-title":"A commonly inherited human PCSK9 germline variant drives breast cancer metastasis via LRP1 receptor","volume":"188","author":"Mei","year":"2025","journal-title":"Cell"},{"key":"10.1016\/j.jvs.2026.04.032_bib62","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1038\/s41586-020-2911-7","article-title":"Inhibition of PCSK9 potentiates immune checkpoint therapy for cancer","volume":"588","author":"Liu","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.jvs.2026.04.032_bib63","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1161\/ATVBAHA.123.320391","article-title":"Disruption of PCSK9 suppresses inflammation and attenuates abdominal aortic aneurysm formation","volume":"45","author":"Peng","year":"2025","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jvs.2026.04.032_bib64","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1161\/CIRCULATIONAHA.120.047544","article-title":"Genetic architecture of abdominal aortic aneurysm in the Million Veteran Program","volume":"142","author":"Klarin","year":"2020","journal-title":"Circulation"},{"key":"10.1016\/j.jvs.2026.04.032_bib65","doi-asserted-by":"crossref","first-page":"1831","DOI":"10.1038\/s41588-023-01510-y","article-title":"Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target","volume":"55","author":"Roychowdhury","year":"2023","journal-title":"Nat Genet"},{"key":"10.1016\/j.jvs.2026.04.032_bib66","doi-asserted-by":"crossref","first-page":"3671","DOI":"10.1038\/s41467-023-39136-7","article-title":"Pan-cancer and cross-population genome-wide association studies dissect shared genetic backgrounds underlying carcinogenesis","volume":"14","author":"Sato","year":"2023","journal-title":"Nat Commun"},{"key":"10.1016\/j.jvs.2026.04.032_bib67","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.ejvs.2023.11.002","article-title":"Editor\u2019s choice -- European Society for Vascular Surgery (ESVS) 2024 clinical practice guidelines on the management of abdominal aorto-iliac artery aneurysms","volume":"67","author":"Wanhainen","year":"2024","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib68","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1093\/ehjci\/jeae103","article-title":"Aortic aneurysms in a general population cohort: prevalence and risk factors in men and women","volume":"25","author":"Pham","year":"2024","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"10.1016\/j.jvs.2026.04.032_bib69","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1016\/j.jvs.2022.02.058","article-title":"Epidemiology of age-, sex-, and race-specific hospitalizations for abdominal aortic aneurysms highlights gaps in current screening recommendations","volume":"76","author":"Li","year":"2022","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib70","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1038\/s41416-025-03028-y","article-title":"Sex differences in cancer incidence: prospective analyses in the UK biobank","volume":"133","author":"Khan","year":"2025","journal-title":"Br J Cancer"},{"key":"10.1016\/j.jvs.2026.04.032_bib71","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1093\/ajh\/hpac054","article-title":"Medication-na\u00efve blood pressure and incident cancers: analysis of 2 nationwide population-based databases","volume":"35","author":"Kaneko","year":"2022","journal-title":"Am J Hypertens"},{"key":"10.1016\/j.jvs.2026.04.032_bib72","doi-asserted-by":"crossref","first-page":"2681","DOI":"10.1002\/ijc.32576","article-title":"Blood pressure and risk of cancer in the European prospective investigation into cancer and nutrition","volume":"146","author":"Christakoudi","year":"2020","journal-title":"Int J Cancer"},{"key":"10.1016\/j.jvs.2026.04.032_bib73","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1158\/1055-9965.EPI-21-1318","article-title":"Causal association between chronic kidney disease and risk of 19 site-specific cancers: a mendelian randomization study","volume":"31","author":"Tang","year":"2022","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.jvs.2026.04.032_bib74","doi-asserted-by":"crossref","first-page":"3269","DOI":"10.2147\/COPD.S539213","article-title":"Chronic obstructive pulmonary disease and lung cancer: a meta-analysis of risk association","volume":"20","author":"Qiao","year":"2025","journal-title":"Int J Chronic Obstr Pulmon Dis"},{"key":"10.1016\/j.jvs.2026.04.032_bib75","first-page":"813","article-title":"Endovascular and open repair of abdominal aortic aneurysm","volume":"117","author":"Schmitz-Rixen","year":"2020","journal-title":"Dtsch Arztebl Int"},{"key":"10.1016\/j.jvs.2026.04.032_bib76","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/j.jvs.2012.02.061","article-title":"Estimating the risk of solid organ malignancy in patients undergoing routine computed tomography scans after endovascular aneurysm repair","volume":"56","author":"Motaganahalli","year":"2012","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib77","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.cyto.2014.07.256","article-title":"Inflammatory mediators after endovascular aortic aneurysm repair","volume":"70","author":"Nessvi Otterhag","year":"2014","journal-title":"Cytokine"},{"key":"10.1016\/j.jvs.2026.04.032_bib78","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.xjtc.2020.01.008","article-title":"Inflammatory cytokines and experimental arterial and vein grafts","volume":"1","author":"Sterpetti","year":"2020","journal-title":"JTCVS Tech"},{"key":"10.1016\/j.jvs.2026.04.032_bib79","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1583\/1074-6218(1997)004<0169:BRTETO>2.0.CO;2","article-title":"Biological responses to endovascular treatment of abdominal aortic aneurysms","volume":"4","author":"Norgren","year":"1997","journal-title":"J Endovasc Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib80","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/j.jvs.2012.09.034","article-title":"The impact of endograft type on inflammatory response after endovascular treatment of abdominal aortic aneurysm","volume":"57","author":"Moulakakis","year":"2013","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib81","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1016\/j.jvs.2022.04.033","article-title":"Outcomes of endovascular abdominal aortic aneurysm repair conversion in octogenarians treated at a high-volume aorta center","volume":"76","author":"Jacobs","year":"2022","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib82","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.avsg.2023.01.007","article-title":"Frailty among veterans undergoing abdominal aortic aneurysm repair","volume":"92","author":"Chen","year":"2023","journal-title":"Ann Vasc Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib83","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.jvs.2014.08.068","article-title":"Open repair versus fenestrated endovascular aneurysm repair of juxtarenal aneurysms","volume":"61","author":"Rao","year":"2015","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib84","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1093\/clinchem\/hvad202","article-title":"Epidemiology of cancer","volume":"70","author":"Schwartz","year":"2024","journal-title":"Clin Chem"},{"key":"10.1016\/j.jvs.2026.04.032_bib85","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1038\/nature05985","article-title":"The common biology of cancer and ageing","volume":"448","author":"Finkel","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.jvs.2026.04.032_bib86","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.ejvs.2025.08.007","article-title":"Editor\u2019s choice - trends in treatment strategies and peri-operative outcomes for complex abdominal aortic aneurysms: a VASCUNET report","volume":"71","author":"Meuli","year":"2026","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib87","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1002\/wjs.70290","article-title":"Trends in abdominal aortic aneurysm management in France between 2012 and 2021 from the French nationwide database: treatment modalities and outcomes","volume":"50","author":"Mesnard","year":"2026","journal-title":"World J Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib88","article-title":"Diabetes and tumor risk: a 23-year danish national cohort study","volume":"16","author":"Skovbjerg","year":"2025","journal-title":"Front Endocrinol"},{"key":"10.1016\/j.jvs.2026.04.032_bib89","doi-asserted-by":"crossref","first-page":"1851","DOI":"10.1158\/1055-9965.EPI-15-0359","article-title":"Potential biases introduced by conflating screening and diagnostic testing in colorectal cancer screening surveillance","volume":"24","author":"Becker","year":"2015","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.jvs.2026.04.032_bib90","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s42155-018-0016-2","article-title":"Incidental extravascular findings in CT angiograms in patients post endovascular abdominal aortic aneurysm repair: clinical relevance and frequency","volume":"1","author":"Dhillon","year":"2018","journal-title":"CVIR Endovasc"},{"key":"10.1016\/j.jvs.2026.04.032_bib91","first-page":"S1078","article-title":"Screen detected abdominal aortic aneurysms and synchronous cancer in men","volume":"2","author":"A","year":"2025","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib92","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.jvs.2017.10.044","article-title":"The society for vascular surgery practice guidelines on the care of patients with an abdominal aortic aneurysm","volume":"67","author":"Chaikof","year":"2018","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib93","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1001\/jamainternmed.2025.0505","article-title":"Projected lifetime cancer risks from current computed tomography imaging","volume":"185","author":"Smith-Bindman","year":"2025","journal-title":"JAMA Intern Med"},{"key":"10.1016\/j.jvs.2026.04.032_bib94","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1161\/STROKEAHA.118.022454","article-title":"Risk of radiation-induced cancer from computed tomography angiography use in imaging surveillance for unruptured cerebral aneurysms","volume":"50","author":"Malhotra","year":"2019","journal-title":"Stroke"},{"key":"10.1016\/j.jvs.2026.04.032_bib95","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1002\/jso.2930390211","article-title":"Concomitant abdominal aortic aneurysm and malignant disease: a difficult management problem","volume":"39","author":"Morris","year":"1988","journal-title":"J Surg Oncol"},{"key":"10.1016\/j.jvs.2026.04.032_bib96","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1053\/ejvs.1999.0925","article-title":"Management of co-existing intra-abdominal disease in aortic surgery","volume":"19","author":"Oshodi","year":"2000","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib97","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1007\/PL00012333","article-title":"Intraabdominal nonvascular operations combined with abdominal aortic aneurysm repair","volume":"23","author":"Tsuji","year":"1999","journal-title":"World J Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib98","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1007\/s00268-001-0244-8","article-title":"One-stage surgical management of concomitant abdominal aortic aneurysm and gastric or colorectal cancer","volume":"26","author":"Matsumoto","year":"2002","journal-title":"World J Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib99","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s10350-004-6138-8","article-title":"Management of patients with colorectal cancer and concomitant abdominal aortic aneurysm","volume":"45","author":"Baxter","year":"2002","journal-title":"Dis Colon Rectum"},{"key":"10.1016\/j.jvs.2026.04.032_bib100","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.ejvs.2006.10.020","article-title":"The high prevalence of colorectal neoplasms in preoperative patients with abdominal aortic aneurysm or peripheral artery disease","volume":"33","author":"Yamamoto","year":"2007","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib101","first-page":"1","article-title":"Long-term results and prognostic factors after repair of abdominal aortic aneurysm with concomitant malignancy","volume":"37","author":"Onohara","year":"1996","journal-title":"J Cardiovasc Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib102","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1007\/PL00013189","article-title":"Surgical strategy for abdominal aortic aneurysm with concurrent symptomatic malignancy","volume":"23","author":"Matsumoto","year":"1999","journal-title":"World J Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib103","first-page":"589","article-title":"The treatment of patients with an unruptured abdominal aortic aneurysm and a concomitant malignancy","volume":"120","author":"Epple","year":"2023","journal-title":"Dtsch Arztebl Int"},{"key":"10.1016\/j.jvs.2026.04.032_bib104","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1016\/j.amjsurg.2021.07.049","article-title":"The prevalence of pancreatic incidentalomas in patients undergoing surveillance for abdominal aortic aneurysms","volume":"222","author":"Portelli Tremont","year":"2021","journal-title":"Am J Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib105","doi-asserted-by":"crossref","first-page":"6247","DOI":"10.3390\/jcm13206247","article-title":"Prognostic impact of pulmonary diseases in 952 patients with thoracic and\/or abdominal aortic aneurysm","volume":"13","author":"Kobayashi","year":"2024","journal-title":"J Clin Med"},{"key":"10.1016\/j.jvs.2026.04.032_bib107","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1016\/j.jvs.2010.09.066","article-title":"The incidence of pulmonary neoplasms discovered by serial computed tomography scanning after endovascular abdominal aortic aneurysm repair","volume":"53","author":"Harthun","year":"2011","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib108","doi-asserted-by":"crossref","first-page":"14","DOI":"10.2310\/6670.2009.00058","article-title":"Infrarenal abdominal aortic aneurysm with concomitant urologic malignancy: treatment results in the era of endovascular aneurysm repair","volume":"18","author":"Habets","year":"2010","journal-title":"Vascular"},{"key":"10.1016\/j.jvs.2026.04.032_bib109","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1007\/s00268-015-3377-x","article-title":"Survival after endovascular abdominal aortic aneurysm repair in a population with a low incidence of coronary artery disease","volume":"40","author":"Sevilla","year":"2016","journal-title":"World J Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib110","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.avsg.2021.11.013","article-title":"Patients on AAA surveillance are at greater threat of cardiovascular events or malignancy than their AAA: outcomes of AAA surveillance over 19 years at a tertiary vascular centre","volume":"83","author":"Haque","year":"2022","journal-title":"Ann Vasc Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib111","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.3390\/jcm13061569","article-title":"Association between PET\/CT scan findings, treatment, and cancer incidence in a cohort of AAA patients","volume":"13","author":"Sakalihasan","year":"2024","journal-title":"J Clin Med"},{"key":"10.1016\/j.jvs.2026.04.032_bib112","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/S0039-6060(98)70262-4","article-title":"Abdominal aortic aneurysms and malignant neoplasia: double jeopardy","volume":"123","author":"Valentine","year":"1998","journal-title":"Surgery"},{"key":"10.1016\/j.jvs.2026.04.032_bib113","doi-asserted-by":"crossref","first-page":"4137","DOI":"10.21873\/anticanres.14413","article-title":"Coprevalence and incidence of lung cancer in patients screened for abdominal aortic aneurysm","volume":"40","author":"Hohneck","year":"2020","journal-title":"Anticancer Res"},{"key":"10.1016\/j.jvs.2026.04.032_bib114","doi-asserted-by":"crossref","first-page":"3847","DOI":"10.3390\/jcm10173847","article-title":"The prevalence of concomitant abdominal aortic aneurysm and cancer","volume":"10","author":"Kim","year":"2021","journal-title":"J Clin Med"},{"key":"10.1016\/j.jvs.2026.04.032_bib115","doi-asserted-by":"crossref","first-page":"2829","DOI":"10.18632\/oncotarget.20181","article-title":"Increased risk of malignancy in patients with an aortic aneurysm: a nationwide population-based retrospective study","volume":"9","author":"Wang","year":"2018","journal-title":"Oncotarget"},{"key":"10.1016\/j.jvs.2026.04.032_bib116","doi-asserted-by":"crossref","first-page":"1694","DOI":"10.1161\/ATVBAHA.123.320543","article-title":"Cancer incidence after diagnosis of abdominal aortic aneurysm-brief report","volume":"44","author":"Luo","year":"2024","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.jvs.2026.04.032_bib117","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.jvs.2022.03.896","article-title":"Risk of various cancers in adults with abdominal aortic aneurysms","volume":"77","author":"Cho","year":"2023","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib118","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1111\/j.1749-6632.1996.tb33299.x","article-title":"Incidence of cancer and abdominal aortic aneurysms. A logistic regression analysis","volume":"800","author":"Chan","year":"1996","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.jvs.2026.04.032_bib119","doi-asserted-by":"crossref","first-page":"1776","DOI":"10.1016\/j.jvs.2018.09.058","article-title":"A population-based cohort study examining the risk of abdominal cancer after endovascular abdominal aortic aneurysm repair","volume":"69","author":"Markar","year":"2019","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib120","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.avsg.2018.08.095","article-title":"Late-onset malignant neoplasms and their prognostic factors after abdominal aortic aneurysm repair","volume":"56","author":"Onohara","year":"2019","journal-title":"Ann Vasc Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib121","doi-asserted-by":"crossref","first-page":"3691","DOI":"10.1007\/s00423-022-02670-x","article-title":"Long-term outcome and cancer incidence after abdominal aortic aneurysm repair","volume":"407","author":"Ettengruber","year":"2022","journal-title":"Langenbecks Arch Surg"},{"key":"10.1016\/j.jvs.2026.04.032_bib122","doi-asserted-by":"crossref","first-page":"6934","DOI":"10.3390\/jcm13226934","article-title":"Sex differences in long-term survival and cancer incidence after ruptured abdominal aortic aneurysm repair","volume":"13","author":"Epple","year":"2024","journal-title":"J Clin Med"},{"issue":"Suppl","key":"10.1016\/j.jvs.2026.04.032_bib123","first-page":"e23344","article-title":"Influence of unruptured abdominal aortic aneurysm (AAA) diagnosis on risk of malignant neoplasms in patients with obesity and ischemic heart disease","volume":"43","author":"Olojakpoke","year":"2025","journal-title":"J Clin Oncol"}],"container-title":["Journal of Vascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0741521426010815?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0741521426010815?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T23:00:52Z","timestamp":1784761252000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0741521426010815"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":121,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["S0741521426010815"],"URL":"https:\/\/doi.org\/10.1016\/j.jvs.2026.04.032","relation":{},"ISSN":["0741-5214"],"issn-type":[{"value":"0741-5214","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A systematic review and meta-analysis of cancer risk in patients with abdominal aortic aneurysm","name":"articletitle","label":"Article Title"},{"value":"Journal of Vascular Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jvs.2026.04.032","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Society for Vascular Surgery. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}