{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T20:33:37Z","timestamp":1793306017510,"version":"4.5.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T00:00:00Z","timestamp":1771545600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jvsvenous.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Vascular Surgery: Venous and Lymphatic Disorders"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.jvsv.2026.102462","type":"journal-article","created":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T00:21:27Z","timestamp":1772151687000},"page":"102462","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Characterization of skin and soft tissue adverse reaction after saphenous vein closure using cyanoacrylate"],"prefix":"10.1016","volume":"14","author":[{"given":"Kazuyo","family":"Sujino","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitsumi","family":"Yamashita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1895-3777","authenticated-orcid":false,"given":"Takaya","family":"Murayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jvsv.2026.102462_bib1","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1177\/0268355518810259","article-title":"Comparison of cyanoacrylate closure and radiofrequency ablation for the treatment of incompetent great saphenous veins: 36-month outcomes of the VeClose randomized controlled trial","volume":"34","author":"Morrison","year":"2019","journal-title":"Phlebology"},{"key":"10.1016\/j.jvsv.2026.102462_bib2","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.jvsv.2012.09.010","article-title":"First human use of cyanoacrylate adhesive for treatment of saphenous vein incompetence","volume":"1","author":"Almeida","year":"2013","journal-title":"J Vasc Surg Venous Lymphat Disord"},{"key":"10.1016\/j.jvsv.2026.102462_bib3","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1177\/1708538116651014","article-title":"Cyanoacrylate closure of incompetent great, small and accessory saphenous veins without the use of post-procedure compression: initial outcomes of a post-market evaluation of the VenaSeal system (the WAVES Study)","volume":"25","author":"Gibson","year":"2017","journal-title":"Vascular"},{"key":"10.1016\/j.jvsv.2026.102462_bib4","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.avsg.2018.07.040","article-title":"Clinical features and management of \"Phlebitis-like Abnormal Reaction\" after cyanoacrylate closure for the treatment of incompetent saphenous veins","volume":"55","author":"Park","year":"2019","journal-title":"Ann Vasc Surg"},{"key":"10.1016\/j.jvsv.2026.102462_bib5","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.jvscit.2019.05.004","article-title":"Persistent type IV hypersensitivity after cyanoacrylate closure of the great saphenous vein","volume":"5","author":"Jones","year":"2019","journal-title":"J Vasc Surg Cases Innov Tech"},{"key":"10.1016\/j.jvsv.2026.102462_bib6","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1111\/cod.13431","article-title":"Allergic contact dermatitis with systemic symptoms caused by VenaSeal","volume":"82","author":"Navarro-Trivino","year":"2020","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.jvsv.2026.102462_bib7","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1111\/cod.13206","article-title":"Allergic contact dermatitis caused by VenaSeal tissue adhesive","volume":"80","author":"Watts","year":"2019","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.jvsv.2026.102462_bib8","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.jvscit.2020.03.011","article-title":"VenaSeal closure despite allergic reaction to n-butyl cyanoacrylate","volume":"6","author":"Fiengo","year":"2020","journal-title":"J Vasc Surg Cases Innov Tech"},{"key":"10.1016\/j.jvsv.2026.102462_bib9","article-title":"Severe adverse reactions after cyanoacrylate endovenous ablation","volume":"9","author":"Louden","year":"2023","journal-title":"J Vasc Surg Cases Innov Tech"},{"key":"10.1016\/j.jvsv.2026.102462_bib10","article-title":"Safety assessment of cyanoacrylate closure for treatment of varicose veins in a large-scale national survey in Japan","volume":"13","author":"Umetsu","year":"2025","journal-title":"J Vasc Surg Venous Lymphat Disord"},{"key":"10.1016\/j.jvsv.2026.102462_bib11","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1080\/17434440.2017.1378093","article-title":"Expert review on the VenaSeal(R) system for endovenous cyano-acrylate adhesive ablation of incompetent saphenous trunks in patients with varicose veins","volume":"14","author":"Lam","year":"2017","journal-title":"Expert Rev Med Devices"},{"key":"10.1016\/j.jvsv.2026.102462_bib12","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1177\/0268355519878618","article-title":"Frequency and severity of hypersensitivity reactions in patients after VenaSeal cyanoacrylate treatment of superficial venous insufficiency","volume":"35","author":"Gibson","year":"2020","journal-title":"Phlebology"},{"key":"10.1016\/j.jvsv.2026.102462_bib13","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1016\/j.jvsv.2020.12.074","article-title":"Hypersensitivity reaction after cyanoacrylate closure of incompetent saphenous veins in patients with chronic venous disease: a retrospective study","volume":"9","author":"Sermsathanasawadi","year":"2021","journal-title":"J Vasc Surg Venous Lymphat Disord"},{"key":"10.1016\/j.jvsv.2026.102462_bib14","doi-asserted-by":"crossref","first-page":"27","DOI":"10.5758\/vsi.230062","article-title":"Complex Hypersensitivity and Irritation Reaction (CHAIR) phenomenon after cyanoacrylate closure of varicose vein","volume":"39","author":"Joh","year":"2023","journal-title":"Vasc Specialist Int"},{"key":"10.1016\/j.jvsv.2026.102462_bib15","doi-asserted-by":"crossref","first-page":"21","DOI":"10.3400\/avd.oa.23-00106","article-title":"Serious adverse events with cyanoacrylate closure of varicose veins: an initial report from a large-scale national survey in Japan","volume":"17","author":"Umetsu","year":"2024","journal-title":"Ann Vasc Dis"},{"key":"10.1016\/j.jvsv.2026.102462_bib16","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1016\/j.jvsv.2023.03.018","article-title":"Cyanoacrylate glue reactions: a systematic review, cases, and proposed mechanisms","volume":"11","author":"Athavale","year":"2023","journal-title":"J Vasc Surg Venous Lymphat Disord"},{"key":"10.1016\/j.jvsv.2026.102462_bib17","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.avsg.2023.06.002","article-title":"Type IV hypersensitivity reaction after cyanoacrylate venous closure","volume":"95","author":"O'Banion","year":"2023","journal-title":"Ann Vasc Surg"},{"key":"10.1016\/j.jvsv.2026.102462_bib18","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1024\/0301-1526\/a000797","article-title":"Histopathological changes to the vascular wall after treatment of great saphenous veins using n-butyl-2-cyanoacrylate","volume":"48","author":"Novotny","year":"2019","journal-title":"Vasa"},{"key":"10.1016\/j.jvsv.2026.102462_bib19","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1097\/HJH.0b013e3283472643","article-title":"Peripheral edema associated with calcium channel blockers: incidence and withdrawal rate--a meta-analysis of randomized trials","volume":"29","author":"Makani","year":"2011","journal-title":"J Hypertens"},{"key":"10.1016\/j.jvsv.2026.102462_bib20","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1258\/phleb.2011.011084","article-title":"Novel vein closure procedure using a proprietary cyanoacrylate adhesive: 30-day swine model results","volume":"27","author":"Min","year":"2012","journal-title":"Phlebology"},{"key":"10.1016\/j.jvsv.2026.102462_bib21","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1097\/DSS.0000000000003183","article-title":"Cyanoacrylate granuloma after cyanoacrylate closure of incompetent saphenous veins","volume":"47","author":"Sermsathanasawadi","year":"2021","journal-title":"Dermatol Surg"},{"key":"10.1016\/j.jvsv.2026.102462_bib22","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.jvsv.2019.04.014","article-title":"Saphenous vein histopathology 5.5 years after cyanoacrylate closure","volume":"8","author":"Almeida","year":"2020","journal-title":"J Vasc Surg Venous Lymphat Disord"},{"key":"10.1016\/j.jvsv.2026.102462_bib23","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1097\/DER.0000000000000514","article-title":"Patch testing ingredients of dermabond and other cyanoacrylate-containing adhesives","volume":"30","author":"Cook","year":"2019","journal-title":"Dermatitis"},{"key":"10.1016\/j.jvsv.2026.102462_bib24","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1111\/cod.12497","article-title":"Contact allergy resulting from the use of acrylate nails is increasing in both users and those who are occupationally exposed","volume":"74","author":"Montgomery","year":"2016","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.jvsv.2026.102462_bib25","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1111\/cod.12000","article-title":"Allergic contact dermatitis caused by a cyanoacrylate-containing false eyelash glue","volume":"67","author":"Shanmugam","year":"2012","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.jvsv.2026.102462_bib26","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1111\/cod.13125","article-title":"Allergic contact dermatitis caused by Dermabond in a paediatric patient undergoing skin surgery","volume":"80","author":"Liu","year":"2019","journal-title":"Contact Dermatitis"},{"key":"10.1016\/j.jvsv.2026.102462_bib27","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1111\/cod.13700","article-title":"Allergic contact dermatitis due to the liquid skin adhesive Dermabond(R) predominantly occurs after the first exposure","volume":"84","author":"Asai","year":"2021","journal-title":"Contact Dermatitis"}],"container-title":["Journal of Vascular Surgery: Venous and Lymphatic Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213333X26000223?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213333X26000223?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T20:24:49Z","timestamp":1793305489000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213333X26000223"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["S2213333X26000223"],"URL":"https:\/\/doi.org\/10.1016\/j.jvsv.2026.102462","relation":{},"ISSN":["2213-333X"],"issn-type":[{"value":"2213-333X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characterization of skin and soft tissue adverse reaction after saphenous vein closure using cyanoacrylate","name":"articletitle","label":"Article Title"},{"value":"Journal of Vascular Surgery: Venous and Lymphatic Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jvsv.2026.102462","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Inc. on behalf of the Society for Vascular Surgery.","name":"copyright","label":"Copyright"}],"article-number":"102462"}}