{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T20:33:19Z","timestamp":1793305999756,"version":"4.5.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T00:00:00Z","timestamp":1773619200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jvsvenous.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Vascular Surgery: Venous and Lymphatic Disorders"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.jvsv.2026.102489","type":"journal-article","created":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T00:24:28Z","timestamp":1774052668000},"page":"102489","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Short-term outcomes of ultrasound-assisted catheter-directed thrombolysis and mechanical thrombectomy in management of intermediate-risk pulmonary embolism"],"prefix":"10.1016","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5745-2882","authenticated-orcid":false,"given":"Crista E.","family":"Horton","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew S.","family":"Wi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Sayegh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas","family":"Mancuso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren A.","family":"Huntress","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph A.","family":"Savarese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-4697-2015","authenticated-orcid":false,"given":"John J.","family":"Ricotta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph J.","family":"Ricotta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jvsv.2026.102489_bib1","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1093\/eurheartj\/ehz405","article-title":"2019 ESC guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS)","volume":"41","author":"Konstantinides","year":"2020","journal-title":"Eur Hear J"},{"key":"10.1016\/j.jvsv.2026.102489_bib2","doi-asserted-by":"crossref","first-page":"2533","DOI":"10.3390\/jcm11092533","article-title":"Risk stratification in patients with acute pulmonary embolism: current evidence and perspectives","volume":"11","author":"Leidi","year":"2022","journal-title":"J Clin Med"},{"key":"10.1016\/j.jvsv.2026.102489_bib3","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1055\/s-0042-1756218","article-title":"Classification and stratification of pulmonary embolisms","volume":"31","author":"Russell","year":"2022","journal-title":"Int J Angiol"},{"key":"10.1016\/j.jvsv.2026.102489_bib4","doi-asserted-by":"crossref","DOI":"10.1513\/AnnalsATS.201504-202OC","article-title":"Identification of low-risk patients with acute symptomatic pulmonary embolism for outpatient therapy","volume":"12","author":"Maestre","year":"2015","journal-title":"Ann Am Thorac Soc"},{"key":"10.1016\/j.jvsv.2026.102489_bib6","doi-asserted-by":"crossref","first-page":"567","DOI":"10.2147\/VHRM.S4861","article-title":"Prognostic stratification of acute pulmonary embolism: focus on clinical aspects, imaging, and biomarkers","volume":"5","author":"Masotti","year":"2009","journal-title":"Vasc Heal Risk Manag"},{"key":"10.1016\/j.jvsv.2026.102489_bib7","first-page":"e977","article-title":"2026 AHA\/ACC\/ACCP\/ACEP\/CHEST\/SCAI\/SHM\/SIR\/SVM\/SVN Guideline for the Evaluation and Management of Acute Pulmonary Embolism in Adults: A Report of the American College of Cardiology\/American Heart Association Joint Committee on Clinical Practice Guidelines","volume":"153","author":"Creager","year":"2026","journal-title":"Circulation"},{"key":"10.1016\/j.jvsv.2026.102489_bib8","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0188862","article-title":"Accuracy and reproducibility of CT right-to-left ventricular diameter measurement in patients with acute pulmonary embolism","volume":"12","author":"Ende-Verhaar","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.jvsv.2026.102489_bib9","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1055\/s-0043-1769590","article-title":"Does adding the pulmonary infarction and right ventricle to left ventricle diameter ratio to the Qanadli index (A combined Qanadli index) more accurately, predict short-term mortality in patients with pulmonary embolism?","volume":"33","author":"Akhoundi","year":"2023","journal-title":"Indian J Radiol Imaging"},{"key":"10.1016\/j.jvsv.2026.102489_bib10","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1161\/CIRCULATIONAHA.106.680421","article-title":"Prognostic value of troponins in acute pulmonary embolism","volume":"116","author":"Becattini","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.jvsv.2026.102489_bib11","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1183\/09031936.00211613","article-title":"Validation of N-terminal pro-brain natriuretic peptide cut-off values for risk stratification of pulmonary embolism","volume":"43","author":"Lankeit","year":"2014","journal-title":"Eur Respir J"},{"key":"10.1016\/j.jvsv.2026.102489_bib12","doi-asserted-by":"crossref","first-page":"365","DOI":"10.4070\/kcj.2017.0314","article-title":"Acute pulmonary embolism: focus on the clinical picture","volume":"48","author":"Morrone","year":"2017","journal-title":"Korean Circ J"},{"key":"10.1016\/j.jvsv.2026.102489_bib13","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1378\/chest.07-1231","article-title":"Prognostic value of echocardiographic right\/left ventricular end-diastolic diameter ratio in patients with acute pulmonary embolism results from a monocenter registry of 1,416 patients","volume":"133","author":"Fr\u00e9mont","year":"2008","journal-title":"Chest"},{"key":"10.1016\/j.jvsv.2026.102489_bib14","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1111\/acem.13108","article-title":"Assessment of right ventricular strain by computed tomography versus echocardiography in acute pulmonary embolism","volume":"24","author":"Dudzinski","year":"2017","journal-title":"Acad Emerg Med"},{"key":"10.1016\/j.jvsv.2026.102489_bib15","doi-asserted-by":"crossref","first-page":"2201","DOI":"10.1111\/j.1538-7836.2011.04490.x","article-title":"The effects of cause of death classification on prognostic assessment of patients with pulmonary embolism","volume":"9","author":"Sanchez","year":"2011","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.jvsv.2026.102489_bib16","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1016\/j.jcin.2018.04.008","article-title":"A randomized trial of the optimum duration of acoustic pulse thrombolysis procedure in acute intermediate-risk pulmonary embolism the OPTALYSE PE trial","volume":"11","author":"Tapson","year":"2018","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jvsv.2026.102489_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.thromres.2025.109503","article-title":"Has systemic thrombolysis run its course? A systematic review and network meta-analysis of patients with intermediate- and high-risk pulmonary embolism","volume":"255","author":"Aviel","year":"2025","journal-title":"Thromb Res"},{"key":"10.1016\/j.jvsv.2026.102489_bib18","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1001\/jamacardio.2022.3603","article-title":"Catheter-Directed treatment of submassive pulmonary embolism\u2014A cautious step closer?","volume":"7","author":"Hylek","year":"2022","journal-title":"JAMA Cardiol"},{"key":"10.1016\/j.jvsv.2026.102489_bib19","article-title":"The role of EkoSonic endovascular system or EKOS\u00ae in pulmonary embolism","volume":"11","author":"Khan","year":"2019","journal-title":"Cureus"},{"key":"10.1016\/j.jvsv.2026.102489_bib20","doi-asserted-by":"crossref","first-page":"137","DOI":"10.2310\/6670.2009.00063","article-title":"Comparison of percutaneous ultrasound-accelerated thrombolysis versus catheter-directed thrombolysis in patients with acute massive pulmonary embolism","volume":"17 Suppl 3","author":"Lin","year":"2009","journal-title":"Vascular"},{"key":"10.1016\/j.jvsv.2026.102489_bib21","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1161\/CIRCULATIONAHA.113.005544","article-title":"Randomized, controlled trial of ultrasound-assisted catheter-directed thrombolysis for acute intermediate-risk pulmonary embolism","volume":"129","author":"Kucher","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.jvsv.2026.102489_bib22","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1016\/j.jcin.2015.04.020","article-title":"A prospective, single-arm, multicenter trial of ultrasound-facilitated, catheter-directed, low-dose fibrinolysis for acute massive and submassive pulmonary embolism the SEATTLE II study","volume":"8","author":"Piazza","year":"2015","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jvsv.2026.102489_bib25","first-page":"380","article-title":"Prognostic value of echocardiography and spiral computed tomography in patients with pulmonary embolism","volume":"11","author":"Gibson","year":"2005","journal-title":"Curr Opin Pulm Med"},{"key":"10.1016\/j.jvsv.2026.102489_bib26","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1016\/j.jcin.2018.12.022","article-title":"A prospective, single-arm, multicenter trial of catheter-directed mechanical thrombectomy for intermediate-risk acute pulmonary embolism the FLARE Study","volume":"12","author":"Tu","year":"2019","journal-title":"JACC Cardiovasc Interv"},{"key":"10.1016\/j.jvsv.2026.102489_bib27","first-page":"319","article-title":"Indigo aspiration system for treatment of pulmonary embolism results of the EXTRACT-PE trial","volume":"14","author":"Sista","year":"2021","journal-title":"Jacc: Cardiovasc Interv"},{"key":"10.1016\/j.jvsv.2026.102489_bib29","doi-asserted-by":"crossref","first-page":"794","DOI":"10.4274\/dir.2022.221622","article-title":"Mechanical thrombectomy associated with a shorter length of hospital stay and lower readmission rates compared with conservative therapy for acute submassive pulmonary embolism: a propensity-matched analysis","volume":"29","author":"Khazi","year":"2023","journal-title":"Diagn Interv Radiol"},{"key":"10.1016\/j.jvsv.2026.102489_bib30","article-title":"Cost-comparison of mechanical thrombectomy and catheter-directed thrombolysis in intermediate-risk pulmonary embolism","volume":"3","author":"Tran","year":"2024","journal-title":"J Soc Cardiovasc Angiogr Interv"},{"key":"10.1016\/j.jvsv.2026.102489_bib28","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1016\/j.jcin.2021.04.049","article-title":"Randomized trial comparing standard versus ultrasound-assisted thrombolysis for submassive pulmonary embolism the SUNSET sPE trial","volume":"14","author":"Avgerinos","year":"2021","journal-title":"JACC Cardiovasc Interv"}],"container-title":["Journal of Vascular Surgery: Venous and Lymphatic Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213333X26000491?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213333X26000491?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T20:23:11Z","timestamp":1793305391000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213333X26000491"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["S2213333X26000491"],"URL":"https:\/\/doi.org\/10.1016\/j.jvsv.2026.102489","relation":{},"ISSN":["2213-333X"],"issn-type":[{"value":"2213-333X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Short-term outcomes of ultrasound-assisted catheter-directed thrombolysis and mechanical thrombectomy in management of intermediate-risk pulmonary embolism","name":"articletitle","label":"Article Title"},{"value":"Journal of Vascular Surgery: Venous and Lymphatic Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jvsv.2026.102489","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Inc. on behalf of the Society for Vascular Surgery.","name":"copyright","label":"Copyright"}],"article-number":"102489"}}