{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T13:36:41Z","timestamp":1792849001810,"version":"4.5.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2027,1,1]],"date-time":"2027-01-01T00:00:00Z","timestamp":1798761600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T00:00:00Z","timestamp":1790121600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","jvsvenous.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Vascular Surgery: Venous and Lymphatic Disorders"],"published-print":{"date-parts":[[2027,1]]},"DOI":"10.1016\/j.jvsv.2026.102634","type":"journal-article","created":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T16:05:02Z","timestamp":1790611502000},"page":"102634","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["ARC-VAC Study (Analysis of real-world multicenter experience with the large-bore CLEANER-Vac Thrombectomy System): An analysis of 200 patients"],"prefix":"10.1016","volume":"15","author":[{"given":"Sameh","family":"Sayfo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charbel Y.","family":"Ishak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-6487-0298","authenticated-orcid":false,"given":"Ilan","family":"Rzadkowolsky-Raoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mel M.","family":"Ghaleb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Stibbs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2548-3059","authenticated-orcid":false,"given":"Holly","family":"Harrison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Powell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline","family":"Finley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.jvsv.2026.102634_bib1","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.blre.2009.07.002","article-title":"Basic mechanisms and pathogenesis of venous thrombosis","volume":"23","author":"Esmon","year":"2009","journal-title":"Blood Rev"},{"key":"10.1016\/j.jvsv.2026.102634_bib2","doi-asserted-by":"crossref","first-page":"S276","DOI":"10.21037\/cdt.2017.09.01","article-title":"Deep vein thrombosis: pathogenesis, diagnosis, and medical management","volume":"7","author":"Stone","year":"2017","journal-title":"Cardiovasc Diagn Ther"},{"key":"10.1016\/j.jvsv.2026.102634_bib3","doi-asserted-by":"crossref","first-page":"I22","DOI":"10.1161\/01.CIR.0000078464.82671.78","article-title":"Natural history of venous thromboembolism","volume":"107","author":"Kearon","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.jvsv.2026.102634_bib4","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1172\/JCI60229","article-title":"New insights into the mechanisms of venous thrombosis","volume":"122","author":"Mackman","year":"2012","journal-title":"J Clin Invest"},{"key":"10.1016\/j.jvsv.2026.102634_bib5","doi-asserted-by":"crossref","first-page":"S30","DOI":"10.1016\/S0049-3848(09)70140-9","article-title":"Pathophysiology of venous thrombosis","volume":"123","author":"L\u00f3pez","year":"2009","journal-title":"Thromb Res"},{"key":"10.1016\/j.jvsv.2026.102634_bib6","first-page":"887","article-title":"Catheter-directed thrombolysis for deep venous thrombosis: current status and controversies","volume":"39","author":"Oklu","year":"2013","journal-title":"Semin Thromb Hemost"},{"key":"10.1016\/j.jvsv.2026.102634_bib7","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.jvsv.2021.03.010","article-title":"Histologic assessment of lower extremity deep vein thrombus from patients undergoing percutaneous mechanical thrombectomy","volume":"10","author":"Yuriditsky","year":"2022","journal-title":"J Vasc Surg Venous Lymphat Disord"},{"key":"10.1016\/j.jvsv.2026.102634_bib8","doi-asserted-by":"crossref","first-page":"186","DOI":"10.5152\/eurasianjmed.2019.19291","article-title":"Update on thrombolytic therapy in acute pulmonary thromboembolism","volume":"51","author":"U\u00e7ar","year":"2019","journal-title":"Eurasian J Med"},{"key":"10.1016\/j.jvsv.2026.102634_bib9","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1148\/radiology.211.1.r99ap4739","article-title":"Catheter-directed thrombolysis for lower extremity deep venous thrombosis: report of a national multicenter registry","volume":"211","author":"Mewissen","year":"1999","journal-title":"Radiology"},{"key":"10.1016\/j.jvsv.2026.102634_bib10","doi-asserted-by":"crossref","first-page":"2240","DOI":"10.1056\/NEJMoa1615066","article-title":"Pharmacomechanical catheter-directed thrombolysis for deep-vein thrombosis","volume":"377","author":"Vedantham","year":"2017","journal-title":"N Engl J Med"},{"key":"10.1016\/j.jvsv.2026.102634_bib11","doi-asserted-by":"crossref","first-page":"e40","DOI":"10.1016\/S2352-3026(19)30209-1","article-title":"Ultrasound-accelerated catheter-directed thrombolysis versus anticoagulation for the prevention of post-thrombotic syndrome (CAVA)","volume":"7","author":"Notten","year":"2020","journal-title":"Lancet Haematol"},{"key":"10.1016\/j.jvsv.2026.102634_bib12","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1016\/j.jvsv.2018.08.002","article-title":"Meta-analysis and systematic review of percutaneous mechanical thrombectomy for lower extremity deep vein thrombosis","volume":"6","author":"Wang","year":"2018","journal-title":"J Vasc Surg Venous Lymphat Disord"},{"key":"10.1016\/j.jvsv.2026.102634_bib13","first-page":"1161","article-title":"Outcomes of mechanical thrombectomy for deep vein thrombosis from the all-comer CLOUT registry","volume":"33","author":"Dexter","year":"2022","journal-title":"J Vasc Interv Radiol"},{"key":"10.1016\/j.jvsv.2026.102634_bib14","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1161\/CIRCULATIONAHA.124.072364","article-title":"Large-bore mechanical thrombectomy versus catheter-directed thrombolysis in the management of intermediate-risk pulmonary embolism: primary results of the PEERLESS randomized controlled trial","volume":"151","author":"Jaber","year":"2025","journal-title":"Circulation"},{"key":"10.1016\/j.jvsv.2026.102634_bib15","series-title":"CLEANER vac\u2122 thrombectomy system: instructions for use","year":"2024"},{"key":"10.1016\/j.jvsv.2026.102634_bib16","doi-asserted-by":"crossref","first-page":"75","DOI":"10.4103\/vit.VIT-D-25-00007","article-title":"Real-world multicenter experience with the CLEANER vac\u2122 thrombectomy system: an analysis of the first 30 patients","volume":"8","author":"Stibbs","year":"2025","journal-title":"Vasc Invest Ther"},{"key":"10.1016\/j.jvsv.2026.102634_bib17","doi-asserted-by":"crossref","first-page":"11","DOI":"10.18103\/mra.v13i11.7034","article-title":"Real-world multicenter experience with a novel large-bore thrombectomy system: an analysis of 110 patients","volume":"13","author":"Stibbs","year":"2025","journal-title":"Med Res Arch"},{"key":"10.1016\/j.jvsv.2026.102634_bib18","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.thromres.2017.05.015","article-title":"Venous thromboembolism in the elderly: a narrative review","volume":"155","author":"Tritschler","year":"2017","journal-title":"Thromb Res"},{"key":"10.1016\/j.jvsv.2026.102634_bib19","doi-asserted-by":"crossref","first-page":"S245","DOI":"10.1111\/jth.12940","article-title":"Interventional therapy for venous thromboembolism","volume":"13","author":"Vedantham","year":"2015","journal-title":"J Thromb Haemost"},{"key":"10.1016\/j.jvsv.2026.102634_bib20","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/S0065-3233(05)70008-5","article-title":"Fibrinogen and fibrin","volume":"70","author":"Weisel","year":"2005","journal-title":"Adv Protein Chem"},{"key":"10.1016\/j.jvsv.2026.102634_bib21","series-title":"CLEANER 15\u2122 rotational Thrombectomy System: instructions for use","year":"2024"},{"key":"10.1016\/j.jvsv.2026.102634_bib22","doi-asserted-by":"crossref","DOI":"10.1118\/1.4794493","article-title":"Estimating the viscoelastic modulus of a thrombus using an ultrasonic shear-wave approach","volume":"40","author":"Huang","year":"2013","journal-title":"Med Phys"},{"key":"10.1016\/j.jvsv.2026.102634_bib23","doi-asserted-by":"crossref","first-page":"2510","DOI":"10.1161\/STROKEAHA.120.033527","article-title":"Mechanical characterization of thrombi retrieved with endovascular thrombectomy in acute ischemic stroke","volume":"52","author":"Boodt","year":"2021","journal-title":"Stroke"},{"key":"10.1016\/j.jvsv.2026.102634_bib24","first-page":"565","article-title":"Technical success and short-term results from mechanical thrombectomy for lower extremity iliofemoral deep vein thrombosis using a computer aided mechanical aspiration thrombectomy device","volume":"10","author":"Lichtenberg","year":"2022","journal-title":"J Vasc Surg Venous Lymphat Disord"},{"key":"10.1016\/j.jvsv.2026.102634_bib25","doi-asserted-by":"crossref","first-page":"905","DOI":"10.3174\/ajnr.A5605","article-title":"Under pressure: comparison of aspiration techniques for endovascular mechanical thrombectomy","volume":"39","author":"Nikoubashman","year":"2018","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.1016\/j.jvsv.2026.102634_bib26","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1177\/153100350501700211","article-title":"What is the learning curve for carotid artery stenting with neuroprotection? Analysis of 200 consecutive cases","volume":"17","author":"Lin","year":"2005","journal-title":"Perspect Vasc Surg Endovasc Ther"},{"key":"10.1016\/j.jvsv.2026.102634_bib27","first-page":"158a","article-title":"Assessment of validity and reproducibility of a clinical scale for the post-thrombotic syndrome","volume":"24","author":"Villalta","year":"1994","journal-title":"Haemostasis"},{"key":"10.1016\/j.jvsv.2026.102634_bib28","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.jvsv.2013.06.003","article-title":"Validation of the Villalta score for assessing post-thrombotic syndrome","volume":"2","author":"Lattimer","year":"2014","journal-title":"J Vasc Surg Venous Lymphat Disord"},{"key":"10.1016\/j.jvsv.2026.102634_bib29","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.thromres.2015.11.033","article-title":"The economic burden of incident venous thromboembolism in the United States: a review of estimated attributable healthcare costs","volume":"137","author":"Grosse","year":"2016","journal-title":"Thromb Res"},{"key":"10.1016\/j.jvsv.2026.102634_bib30","first-page":"707","article-title":"Research priorities in venous thromboembolism","volume":"4","author":"Cushman","year":"2020","journal-title":"Res Pract Thromb Haemost"}],"container-title":["Journal of Vascular Surgery: Venous and Lymphatic Disorders"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213333X26001940?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2213333X26001940?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T12:36:52Z","timestamp":1792845412000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2213333X26001940"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2027,1]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2027,1]]}},"alternative-id":["S2213333X26001940"],"URL":"https:\/\/doi.org\/10.1016\/j.jvsv.2026.102634","relation":{},"ISSN":["2213-333X"],"issn-type":[{"value":"2213-333X","type":"print"}],"subject":[],"published":{"date-parts":[[2027,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"ARC-VAC Study (Analysis of real-world multicenter experience with the large-bore CLEANER-Vac Thrombectomy System): An analysis of 200 patients","name":"articletitle","label":"Article Title"},{"value":"Journal of Vascular Surgery: Venous and Lymphatic Disorders","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.jvsv.2026.102634","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Inc. on behalf of the Society for Vascular Surgery.","name":"copyright","label":"Copyright"}],"article-number":"102634"}}