{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T08:50:11Z","timestamp":1790844611267,"version":"4.1.0"},"reference-count":32,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"vor","delay-in-days":1461,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["kidney-international.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1016\/j.kint.2016.06.020","type":"journal-article","created":{"date-parts":[[2016,8,14]],"date-time":"2016-08-14T19:01:22Z","timestamp":1471201282000},"page":"1080-1089","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":71,"title":["The relatively poor correlation between random and\u00a024-hour urine protein excretion in patients with\u00a0biopsy-proven glomerular diseases"],"prefix":"10.1016","volume":"90","author":[{"given":"Marie C.","family":"Hogan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heather N.","family":"Reich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter J.","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon G.","family":"Adler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel C.","family":"Cattran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerald B.","family":"Appel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debbie S.","family":"Gipson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Kretzler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan P.","family":"Troost","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John C.","family":"Lieske","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.kint.2016.06.020_bib1","doi-asserted-by":"crossref","first-page":"3177","DOI":"10.1681\/ASN.2007050526","article-title":"Remission of proteinuria improves prognosis in IgA nephropathy","volume":"18","author":"Reich","year":"2007","journal-title":"J\u00a0Am Soc Nephrol"},{"key":"10.1016\/j.kint.2016.06.020_bib2","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1053\/j.ajkd.2012.02.326","article-title":"Risk stratification of patients with IgA nephropathy","volume":"59","author":"Barbour","year":"2012","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.kint.2016.06.020_bib3","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1111\/j.1523-1755.2004.00873.x","article-title":"Idiopathic membranous nephropathy: definition and relevance of a partial remission","volume":"66","author":"Troyanov","year":"2004","journal-title":"Kidney Int"},{"key":"10.1016\/j.kint.2016.06.020_bib4","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1681\/ASN.2004070593","article-title":"Focal and segmental glomerulosclerosis: definition and relevance of a partial remission","volume":"16","author":"Troyanov","year":"2005","journal-title":"J\u00a0Am Soc Nephrol"},{"key":"10.1016\/j.kint.2016.06.020_bib5","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1053\/ajkd.1998.v32.pm9669427","article-title":"Long-term outcome in children and adults with classic focal segmental glomerulosclerosis","volume":"32","author":"Cattran","year":"1998","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.kint.2016.06.020_bib6","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1038\/ki.2012.280","article-title":"The KDIGO practice guideline on glomerulonephritis: reading between the (guide)lines\u2014application to the individual patient","volume":"82","author":"Radhakrishnan","year":"2012","journal-title":"Kidney Int"},{"key":"10.1016\/j.kint.2016.06.020_bib7","doi-asserted-by":"crossref","first-page":"1122","DOI":"10.1093\/aje\/kwh326","article-title":"Evaluation of measures of urinary albumin excretion in epidemiologic studies","volume":"160","author":"Dyer","year":"2004","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.kint.2016.06.020_bib8","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1046\/j.1464-5491.2000.00200.x","article-title":"Freezing method affects the concentration and variability of urine proteins and the interpretation of data on microalbuminuria","volume":"17","author":"Schultz","year":"2000","journal-title":"Diabet Med"},{"key":"10.1016\/j.kint.2016.06.020_bib9","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1093\/aje\/kwj271","article-title":"Evaluation of measures of urinary albumin excretion","volume":"164","author":"Gansevoort","year":"2006","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.kint.2016.06.020_bib10","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1136\/bmj.316.7130.504","article-title":"Cross sectional longitudinal study of spot morning urine protein:creatinine ratio, 24 hour urine protein excretion rate, glomerular filtration rate, and end stage renal failure in chronic renal disease in patients without diabetes","volume":"316","author":"Ruggenenti","year":"1998","journal-title":"BMJ"},{"key":"10.1016\/j.kint.2016.06.020_bib11","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1016\/S0272-6386(03)00023-4","article-title":"Validity of protein-osmolality versus protein-creatinine ratios in the estimation of quantitative proteinuria from random samples of urine in children","volume":"41","author":"Morgenstern","year":"2003","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.kint.2016.06.020_bib12","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1093\/ajcp\/100.4.419","article-title":"Protein-osmolality ratio for the quantitative assessment of proteinuria from a random urinalysis sample","volume":"100","author":"Wilson","year":"1993","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.kint.2016.06.020_bib13","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.cccn.2004.02.007","article-title":"Determination of reference intervals for serum creatinine, creatinine excretion and creatinine clearance with an enzymatic and a modified Jaffe method","volume":"344","author":"Junge","year":"2004","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.kint.2016.06.020_bib14","doi-asserted-by":"crossref","first-page":"184","DOI":"10.2215\/CJN.05030610","article-title":"Equations to estimate creatinine excretion rate: the CKD epidemiology collaboration","volume":"6","author":"Ix","year":"2011","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.kint.2016.06.020_bib15","doi-asserted-by":"crossref","first-page":"943","DOI":"10.2215\/CJN.08210813","article-title":"Heritability of urinary traits that\u00a0contribute to nephrolithiasis","volume":"9","author":"Lieske","year":"2014","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.kint.2016.06.020_bib16","doi-asserted-by":"crossref","first-page":"e4342","DOI":"10.1136\/bmj.e4342","article-title":"Diagnostic accuracy of spot urinary protein and albumin to creatinine ratios for detection of significant proteinuria or adverse pregnancy outcome in patients with suspected pre-eclampsia: systematic review and meta-analysis","volume":"345","author":"Morris","year":"2012","journal-title":"BMJ"},{"key":"10.1016\/j.kint.2016.06.020_bib17","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.semnephrol.2007.10.001","article-title":"Natural history of primary IgA nephropathy","volume":"28","author":"Berthoux","year":"2008","journal-title":"Semin Nephrol"},{"key":"10.1016\/j.kint.2016.06.020_bib18","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1056\/NEJM198312223092503","article-title":"Use of single voided urine samples to estimate quantitative proteinuria","volume":"309","author":"Ginsberg","year":"1983","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.kint.2016.06.020_bib19","doi-asserted-by":"crossref","first-page":"1577","DOI":"10.1373\/clinchem.2005.049742","article-title":"Use of protein:creatinine ratio measurements on random urine samples for prediction of significant proteinuria: a systematic review","volume":"51","author":"Price","year":"2005","journal-title":"Clin Chem"},{"key":"10.1016\/j.kint.2016.06.020_bib20","first-page":"450","article-title":"Use of the urinary protein creatinine index to assess proteinuria in renal transplant patients","volume":"7","author":"Dyson","year":"1992","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.kint.2016.06.020_bib21","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1097\/00007890-200110270-00021","article-title":"The urine protein to creatinine ratio (P\/C) as a predictor of 24-hour urine protein excretion in renal transplant patients","volume":"72","author":"Torng","year":"2001","journal-title":"Transplantation"},{"key":"10.1016\/j.kint.2016.06.020_bib22","doi-asserted-by":"crossref","first-page":"428","DOI":"10.4103\/0971-4065.120340","article-title":"Accuracy of spot urine protein creatinine ratio in measuring proteinuria in chronic kidney disease stage 3 and 4","volume":"23","author":"Nayak","year":"2013","journal-title":"Indian J Nephrol"},{"key":"10.1016\/j.kint.2016.06.020_bib23","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1016\/0272-6386(95)90054-3","article-title":"The urine protein to creatinine ratio as a predictor of 24-hour urine protein excretion in type 1 diabetic patients with nephropathy","volume":"26","author":"Rodby","year":"1995","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.kint.2016.06.020_bib24","first-page":"211","article-title":"The protein-to-creatinine ratio for the prediction of significant proteinuria in patients at risk for preeclampsia: a meta-analysis","volume":"43","author":"Sanchez-Ramos","year":"2013","journal-title":"Ann Clin Lab Sci"},{"key":"10.1016\/j.kint.2016.06.020_bib25","first-page":"228","article-title":"Muscle protein synthesis is impaired in nephrotic rats","volume":"18","author":"Kaysen","year":"1992","journal-title":"Miner Electrolyte Metab"},{"key":"10.1016\/j.kint.2016.06.020_bib26","doi-asserted-by":"crossref","first-page":"e0137460","DOI":"10.1371\/journal.pone.0137460","article-title":"Diagnostic accuracy of urine protein\/creatinine ratio is influenced by urine concentration","volume":"10","author":"Yang","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.kint.2016.06.020_bib27","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1289\/ehp.7337","article-title":"Urinary creatinine concentrations in the U.S. population: implications for urinary biologic monitoring measurements","volume":"113","author":"Barr","year":"2005","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.kint.2016.06.020_bib28","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1038\/ki.2012.428","article-title":"Design of the Nephrotic Syndrome Study Network (NEPTUNE) to evaluate primary glomerular nephropathy by a multidisciplinary approach","volume":"83","author":"Gadegbeku","year":"2013","journal-title":"Kidney Int"},{"key":"10.1016\/j.kint.2016.06.020_bib29","doi-asserted-by":"crossref","first-page":"81","DOI":"10.2215\/CJN.02560315","article-title":"Complete remission in the nephrotic syndrome study network","volume":"11","author":"Gipson","year":"2016","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.kint.2016.06.020_bib30","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1186\/s12882-015-0185-3","article-title":"Strategy and rationale for urine collection protocols employed in the NEPTUNE study","volume":"16","author":"Hogan","year":"2015","journal-title":"BMC Nephrol"},{"key":"10.1016\/j.kint.2016.06.020_bib31","first-page":"1","article-title":"Estimating the area under a receiver operating characteristic curve for repeated measures design","volume":"8","author":"Liu","year":"2003","journal-title":"J\u00a0Stat Softw"},{"key":"10.1016\/j.kint.2016.06.020_bib32","doi-asserted-by":"crossref","first-page":"2209","DOI":"10.1002\/sim.5654","article-title":"Nonparametric ROC summary statistics for correlated diagnostic marker data","volume":"32","author":"Tang","year":"2013","journal-title":"Stat Med"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S008525381630309X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S008525381630309X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T06:37:20Z","timestamp":1604212640000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S008525381630309X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":32,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["S008525381630309X"],"URL":"https:\/\/doi.org\/10.1016\/j.kint.2016.06.020","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[2016,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The relatively poor correlation between random and\u00a024-hour urine protein excretion in patients with\u00a0biopsy-proven glomerular diseases","name":"articletitle","label":"Article Title"},{"value":"Kidney International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.kint.2016.06.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016, International Society of Nephrology. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}