{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T06:56:52Z","timestamp":1789541812926,"version":"build-2803163510"},"reference-count":45,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,9,1]],"date-time":"2021-09-01T00:00:00Z","timestamp":1630454400000},"content-version":"vor","delay-in-days":1461,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["kidney-international.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[2017,9]]},"DOI":"10.1016\/j.kint.2017.02.016","type":"journal-article","created":{"date-parts":[[2017,4,13]],"date-time":"2017-04-13T00:32:13Z","timestamp":1492043533000},"page":"743-750","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":39,"title":["Acute kidney injury is associated with microvascular myocardial damage following myocardial infarction"],"prefix":"10.1016","volume":"92","author":[{"given":"Sebastian Johannes","family":"Reinstadler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andreas","family":"Kronbichler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Reindl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans-Josef","family":"Feistritzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronika","family":"Innerhofer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnes","family":"Mayr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gert","family":"Klug","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Tiefenthaler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gert","family":"Mayer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard","family":"Metzler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.kint.2017.02.016_bib1","doi-asserted-by":"crossref","first-page":"3365","DOI":"10.1681\/ASN.2004090740","article-title":"Acute kidney injury, mortality, length of stay, and costs in hospitalized patients","volume":"16","author":"Chertow","year":"2005","journal-title":"J\u00a0Am Soc Nephrol"},{"key":"10.1016\/j.kint.2017.02.016_bib2","doi-asserted-by":"crossref","first-page":"448","DOI":"10.2215\/CJN.02440213","article-title":"Association between AKI and long-term renal and cardiovascular outcomes in United States veterans","volume":"9","author":"Chawla","year":"2014","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.kint.2017.02.016_bib3","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1681\/ASN.2016010105","article-title":"AKI and long-term risk for cardiovascular events and mortality","volume":"28","author":"Odutayo","year":"2017","journal-title":"J\u00a0Am Soc Nephrol"},{"key":"10.1016\/j.kint.2017.02.016_bib4","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1001\/archinte.168.9.987","article-title":"Long-term prognosis of acute kidney injury after acute myocardial infarction","volume":"168","author":"Parikh","year":"2008","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.kint.2017.02.016_bib5","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.ijcard.2014.03.146","article-title":"Association of contrast-induced acute kidney injury with long-term cardiovascular events in acute coronary syndrome patients with chronic kidney disease undergoing emergent percutaneous coronary intervention","volume":"174","author":"Watabe","year":"2014","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.kint.2017.02.016_bib6","doi-asserted-by":"crossref","first-page":"e002475","DOI":"10.1161\/CIRCINTERVENTIONS.114.002475","article-title":"Impact of contrast-induced acute kidney injury after percutaneous coronary intervention on short- and long-term outcomes: pooled analysis from the HORIZONS-AMI and ACUITY Trials","volume":"8","author":"Giacoppo","year":"2015","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.kint.2017.02.016_bib7","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.amjcard.2014.11.002","article-title":"Association of left ventricular function and acute kidney injury among ST-elevation myocardial infarction patients treated by primary percutaneous intervention","volume":"115","author":"Shacham","year":"2015","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.kint.2017.02.016_bib8","first-page":"169","article-title":"Acute kidney injury among ST elevation myocardial infarction patients treated by primary percutaneous coronary intervention: a multifactorial entity","volume":"29","author":"Shacham","year":"2016","journal-title":"J\u00a0Nephrol"},{"key":"10.1016\/j.kint.2017.02.016_bib9","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1253\/circj.CJ-14-0438","article-title":"Acute kidney injury and acute myocardial infarction","volume":"78","author":"Ebina","year":"2014","journal-title":"Circ J"},{"key":"10.1016\/j.kint.2017.02.016_bib10","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1007\/s11255-010-9798-4","article-title":"Impact of heart failure on the incidence of contrast-induced nephropathy in patients with chronic kidney disease","volume":"42","author":"Rosenstock","year":"2010","journal-title":"Int Urol Nephrol"},{"key":"10.1016\/j.kint.2017.02.016_bib11","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1681\/ASN.2006010017","article-title":"Update on mechanisms of ischemic acute kidney injury","volume":"17","author":"Devarajan","year":"2006","journal-title":"J\u00a0Am Soc Nephrol"},{"key":"10.1016\/j.kint.2017.02.016_bib12","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/1532-429X-14-46","article-title":"Prognostic value at 5 years of microvascular obstruction after acute myocardial infarction assessed by cardiovascular magnetic resonance","volume":"14","author":"Klug","year":"2012","journal-title":"J\u00a0Cardiovasc Magn Reson"},{"key":"10.1016\/j.kint.2017.02.016_bib13","article-title":"Relation of inflammatory markers with myocardial and microvascular injury in patients with reperfused ST-elevation myocardial infarction","author":"Reindl","year":"2016","journal-title":"Eur Heart J Acute Cardiovasc Care"},{"key":"10.1016\/j.kint.2017.02.016_bib14","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1097\/HCO.0000000000000227","article-title":"Risk stratification by cardiac magnetic resonance imaging after ST-elevation myocardial infarction","volume":"30","author":"Reinstadler","year":"2015","journal-title":"Curr Opin Cardiol"},{"key":"10.1016\/j.kint.2017.02.016_bib15","doi-asserted-by":"crossref","first-page":"1780","DOI":"10.1016\/j.jacc.2004.07.043","article-title":"Contrast-induced nephropathy in patients undergoing primary angioplasty for acute myocardial infarction","volume":"44","author":"Marenzi","year":"2004","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.kint.2017.02.016_bib16","doi-asserted-by":"crossref","first-page":"170","DOI":"10.7326\/0003-4819-150-3-200902030-00006","article-title":"Contrast volume during primary percutaneous coronary intervention and subsequent contrast-induced nephropathy and mortality","volume":"150","author":"Marenzi","year":"2009","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.kint.2017.02.016_bib17","article-title":"Echocardiographic correlates of left ventricular filling pressures and acute cardio-renal syndrome in ST segment elevation myocardial infarction patients","author":"Flint","year":"2016","journal-title":"Clin Res Cardiol"},{"key":"10.1016\/j.kint.2017.02.016_bib18","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1056\/NEJMoa021833","article-title":"Nephrotoxic effects in high-risk patients undergoing angiography","volume":"348","author":"Aspelin","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.kint.2017.02.016_bib19","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1016\/j.ahj.2010.09.022","article-title":"Acute hyperglycemia and contrast-induced nephropathy in primary percutaneous coronary intervention","volume":"160","author":"Marenzi","year":"2010","journal-title":"Am Heart J"},{"key":"10.1016\/j.kint.2017.02.016_bib20","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1002\/clc.22290","article-title":"Hyperglycemia in patients referred for cardiac catheterization is associated with preexisting diabetes rather than a stress-related phenomenon: a prospective cross-sectional study","volume":"37","author":"Arbel","year":"2014","journal-title":"Clin Cardiol"},{"key":"10.1016\/j.kint.2017.02.016_bib21","first-page":"305","article-title":"Systemic inflammatory response following acute myocardial infarction","volume":"12","author":"Fang","year":"2015","journal-title":"J\u00a0Geriatr Cardiol"},{"key":"10.1016\/j.kint.2017.02.016_bib22","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1007\/s10157-014-1071-1","article-title":"High sensitive C-reactive protein and the risk of acute kidney injury among ST elevation myocardial infarction patients undergoing primary percutaneous intervention","volume":"19","author":"Shacham","year":"2015","journal-title":"Clin Exp Nephrol"},{"key":"10.1016\/j.kint.2017.02.016_bib23","doi-asserted-by":"crossref","first-page":"1778","DOI":"10.1136\/heartjnl-2015-307773","article-title":"Acute kidney injury in patients with acute coronary syndromes","volume":"101","author":"Marenzi","year":"2015","journal-title":"Heart"},{"key":"10.1016\/j.kint.2017.02.016_bib24","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/j.ahj.2014.11.019","article-title":"Prognostic significance of serum creatinine and its change patterns in patients with acute coronary syndromes","volume":"169","author":"Marenzi","year":"2015","journal-title":"Am Heart J"},{"key":"10.1016\/j.kint.2017.02.016_bib25","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1038\/ki.2012.118","article-title":"Composition and plaque patterns of coronary culprit lesions and clinical characteristics of patients with chronic kidney disease","volume":"82","author":"Kono","year":"2012","journal-title":"Kidney Int"},{"key":"10.1016\/j.kint.2017.02.016_bib26","first-page":"1240","article-title":"Acute cardio-renal syndrome as a cause for renal deterioration among myocardial infarction patients treated with primary percutaneous intervention","volume":"31","author":"Shacham","year":"2015","journal-title":"Can J Cardiol"},{"key":"10.1016\/j.kint.2017.02.016_bib27","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1111\/echo.13206","article-title":"Relation of pulmonary artery pressure and renal impairment in ST segment elevation myocardial infarction patients","volume":"33","author":"Shacham","year":"2016","journal-title":"Echocardiography"},{"key":"10.1016\/j.kint.2017.02.016_bib28","doi-asserted-by":"crossref","first-page":"1814","DOI":"10.1016\/S0140-6736(14)60689-9","article-title":"Haemodynamic-guided fluid administration for the prevention of contrast-induced acute kidney injury: the POSEIDON randomised controlled trial","volume":"383","author":"Brar","year":"2014","journal-title":"Lancet"},{"key":"10.1016\/j.kint.2017.02.016_bib29","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1159\/000443621","article-title":"Prognostic implications of acute renal impairment among ST elevation myocardial infarction patients with preserved left ventricular function","volume":"6","author":"Shacham","year":"2016","journal-title":"Cardiorenal Med"},{"key":"10.1016\/j.kint.2017.02.016_bib30","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.ijcard.2015.09.001","article-title":"High-sensitivity troponin T for prediction of left ventricular function and infarct size one year following ST-elevation myocardial infarction","volume":"202","author":"Reinstadler","year":"2016","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.kint.2017.02.016_bib31","doi-asserted-by":"crossref","first-page":"79","DOI":"10.3121\/cmr.4.1.79","article-title":"Cardiac enzymes, renal failure and renal transplantation","volume":"4","author":"Bozbas","year":"2006","journal-title":"Clin Med Res"},{"key":"10.1016\/j.kint.2017.02.016_bib32","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1093\/eurheartj\/ehv484","article-title":"Coronary microvascular obstruction in acute myocardial infarction","volume":"37","author":"Niccoli","year":"2016","journal-title":"Eur Heart J"},{"key":"10.1016\/j.kint.2017.02.016_bib33","first-page":"1393","article-title":"A\u00a0simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: development and initial validation","volume":"44","author":"Mehran","year":"2004","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.kint.2017.02.016_bib34","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1161\/CIRCINTERVENTIONS.110.955310","article-title":"Mehran contrast-induced nephropathy risk score predicts short- and long-term clinical outcomes in patients with ST-elevation-myocardial infarction","volume":"3","author":"Sgura","year":"2010","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.kint.2017.02.016_bib35","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1093\/eurheartj\/ehu063","article-title":"Contrast-induced acute kidney injury after primary percutaneous coronary intervention: results from the HORIZONS-AMI substudy","volume":"35","author":"Narula","year":"2014","journal-title":"Eur Heart J"},{"key":"10.1016\/j.kint.2017.02.016_bib36","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.1016\/j.jacc.2014.06.1194","article-title":"Comprehensive prognosis assessment by CMR imaging after ST-segment elevation myocardial infarction","volume":"64","author":"Eitel","year":"2014","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.kint.2017.02.016_bib37","doi-asserted-by":"crossref","first-page":"R31","DOI":"10.1186\/cc5713","article-title":"Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury","volume":"11","author":"Mehta","year":"2007","journal-title":"Critical Care"},{"key":"10.1016\/j.kint.2017.02.016_bib38","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.ijcard.2016.02.086","article-title":"A\u00a0comparison between two different definitions of contrast-induced acute kidney injury in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention","volume":"210","author":"Centola","year":"2016","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.kint.2017.02.016_bib39","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1161\/CIRCIMAGING.111.963421","article-title":"Dynamic changes of edema and late gadolinium enhancement after acute myocardial infarction and their relationship to functional recovery and salvage index","volume":"4","author":"Dall'Armellina","year":"2011","journal-title":"Circ Cardiovasc Imaging"},{"key":"10.1016\/j.kint.2017.02.016_bib40","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1016\/j.jcmg.2014.05.010","article-title":"Prognostic value of microvascular obstruction and infarct size, as measured by CMR in STEMI patients","volume":"7","author":"van Kranenburg","year":"2014","journal-title":"JACC Cardiovasc Imaging"},{"key":"10.1016\/j.kint.2017.02.016_bib41","doi-asserted-by":"crossref","first-page":"2551","DOI":"10.1093\/eurheartj\/ehs184","article-title":"Third universal definition of myocardial infarction","volume":"33","author":"Thygesen","year":"2012","journal-title":"Eur Heart J"},{"key":"10.1016\/j.kint.2017.02.016_bib42","doi-asserted-by":"crossref","first-page":"1970","DOI":"10.1097\/HJH.0000000000000644","article-title":"Aortic stiffness is associated with elevated high-sensitivity cardiac troponin T concentrations at a chronic stage after ST-segment elevation myocardial infarction","volume":"33","author":"Feistritzer","year":"2015","journal-title":"J\u00a0Hypertens"},{"key":"10.1016\/j.kint.2017.02.016_bib43","doi-asserted-by":"crossref","first-page":"2569","DOI":"10.1093\/eurheartj\/ehs215","article-title":"ESC guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation","volume":"33","author":"Steg","year":"2012","journal-title":"Eur Heart J"},{"key":"10.1016\/j.kint.2017.02.016_bib44","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.1016\/j.jacc.2006.01.059","article-title":"Effects of time, dose, and inversion time for acute myocardial infarct size measurements based on magnetic resonance imaging-delayed contrast enhancement","volume":"47","author":"Wagner","year":"2006","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.kint.2017.02.016_bib45","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1080\/10976640601105614","article-title":"Mechanism of late gadolinium enhancement in patients with acute myocardial infarction","volume":"9","author":"Klein","year":"2007","journal-title":"J\u00a0Cardiovasc Magn Reson"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253817301497?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253817301497?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T00:50:39Z","timestamp":1758761439000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253817301497"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9]]},"references-count":45,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,9]]}},"alternative-id":["S0085253817301497"],"URL":"https:\/\/doi.org\/10.1016\/j.kint.2017.02.016","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[2017,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Acute kidney injury is associated with microvascular myocardial damage following myocardial infarction","name":"articletitle","label":"Article Title"},{"value":"Kidney International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.kint.2017.02.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 International Society of Nephrology. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}