{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T17:49:12Z","timestamp":1771955352474,"version":"3.50.1"},"reference-count":8,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,9,2]],"date-time":"2022-09-02T00:00:00Z","timestamp":1662076800000},"content-version":"vor","delay-in-days":1462,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["kidney-international.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1016\/j.kint.2018.05.020","type":"journal-article","created":{"date-parts":[[2018,8,21]],"date-time":"2018-08-21T22:44:38Z","timestamp":1534891478000},"page":"455-457","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Novel role for androgen signaling in pyelonephritis"],"prefix":"10.1016","volume":"94","author":[{"given":"Christina B.","family":"Ching","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brian","family":"Becknell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.kint.2018.05.020_bib1","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/S1047-2797(02)00272-7","article-title":"Acute pyelonephritis in US hospitals in 1997: hospitalization and in-hospital mortality","volume":"13","author":"Foxman","year":"2003","journal-title":"Ann Epidemiol"},{"key":"10.1016\/j.kint.2018.05.020_bib2","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1681\/ASN.2015030327","article-title":"Androgens enhance male urinary tract infection severity in a new model","volume":"27","author":"Olson","year":"2016","journal-title":"J\u00a0Am Soc Nephrol"},{"key":"10.1016\/j.kint.2018.05.020_bib3","first-page":"1371","article-title":"Renal scar formation and kidney function following antibiotic-treated murine pyelonephritis","volume":"10","author":"Olson","year":"2017","journal-title":"Dis Model Mech"},{"key":"10.1016\/j.kint.2018.05.020_bib4","first-page":"502","article-title":"Androgen exposure potentiates formation of intratubular communities and renal abscesses by","volume":"94","author":"Olson","year":"2018","journal-title":"Escherichia coli. Kidney Int"},{"key":"10.1016\/j.kint.2018.05.020_bib5","doi-asserted-by":"crossref","DOI":"10.3390\/pathogens5010002","article-title":"Subversion of host innate immunity by uropathogenic Escherichia coli","volume":"5","author":"Olson","year":"2016","journal-title":"Pathogens"},{"key":"10.1016\/j.kint.2018.05.020_bib6","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1016\/j.cell.2017.07.022","article-title":"Renal sodium gradient orchestrates a dynamic antibacterial defense zone","volume":"170","author":"Berry","year":"2017","journal-title":"Cell"},{"key":"10.1016\/j.kint.2018.05.020_bib7","doi-asserted-by":"crossref","first-page":"2963","DOI":"10.1172\/JCI71630","article-title":"\u03b1-Intercalated cells defend the urinary system from bacterial infection","volume":"124","author":"Paragas","year":"2014","journal-title":"J\u00a0Clin Invest"},{"key":"10.1016\/j.kint.2018.05.020_bib8","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1038\/ki.2012.410","article-title":"Ribonuclease 7, an antimicrobial peptide upregulated during infection, contributes to microbial defense of the human urinary tract","volume":"83","author":"Spencer","year":"2013","journal-title":"Kidney Int"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253818303946?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253818303946?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T00:51:14Z","timestamp":1758761474000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253818303946"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":8,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["S0085253818303946"],"URL":"https:\/\/doi.org\/10.1016\/j.kint.2018.05.020","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Novel role for androgen signaling in pyelonephritis","name":"articletitle","label":"Article Title"},{"value":"Kidney International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.kint.2018.05.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.kint.2018.04.023","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 International Society of Nephrology. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}