{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T17:21:44Z","timestamp":1793380904003,"version":"4.5.0"},"reference-count":52,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"vor","delay-in-days":1461,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["HL116848"],"award-info":[{"award-number":["HL116848"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["HL127240"],"award-info":[{"award-number":["HL127240"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["AG043822"],"award-info":[{"award-number":["AG043822"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["FRN-216927"],"award-info":[{"award-number":["FRN-216927"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["16SFRN31400013"],"award-info":[{"award-number":["16SFRN31400013"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["kidney-international.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[2019,3]]},"DOI":"10.1016\/j.kint.2018.10.020","type":"journal-article","created":{"date-parts":[[2019,1,30]],"date-time":"2019-01-30T01:38:48Z","timestamp":1548812328000},"page":"590-610","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":101,"title":["Metabolomics assessment reveals oxidative stress and altered energy production in the heart after ischemic acute kidney injury in mice"],"prefix":"10.1016","volume":"95","author":[{"given":"Benjamin M.","family":"Fox","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyo-Wook","family":"Gil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lara","family":"Kirkbride-Romeo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rushita A.","family":"Bagchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara A.","family":"Wennersten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Korey R.","family":"Haefner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nataliya I.","family":"Skrypnyk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolyn N.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle E.","family":"Soranno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katja M.","family":"Gist","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin R.","family":"Griffin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Jovanovich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie A.","family":"Reisz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew J.","family":"Wither","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelo","family":"D'Alessandro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles L.","family":"Edelstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan","family":"Clendenen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy A.","family":"McKinsey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Altmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Faubel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.kint.2018.10.020_bib1","doi-asserted-by":"crossref","first-page":"2552","DOI":"10.1097\/CCM.0b013e3181a5906f","article-title":"Incidence and outcomes of acute kidney injury in intensive care units: a Veterans Administration study","volume":"37","author":"Thakar","year":"2009","journal-title":"Crit Care Med"},{"key":"10.1016\/j.kint.2018.10.020_bib2","doi-asserted-by":"crossref","first-page":"844","DOI":"10.2215\/CJN.05191107","article-title":"Diagnosis, epidemiology and outcomes of acute kidney injury","volume":"3","author":"Waikar","year":"2008","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.kint.2018.10.020_bib3","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1681\/ASN.2006050494","article-title":"Acute renal failure after bilateral nephrectomy is associated with cytokine-mediated pulmonary injury","volume":"18","author":"Hoke","year":"2007","journal-title":"J\u00a0Am Soc Nephrol"},{"key":"10.1016\/j.kint.2018.10.020_bib4","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1038\/ki.2011.241","article-title":"The distant organ effects of acute kidney injury","volume":"81","author":"Grams","year":"2012","journal-title":"Kidney Int"},{"key":"10.1016\/j.kint.2018.10.020_bib5","doi-asserted-by":"crossref","first-page":"2337","DOI":"10.1007\/s11255-014-0766-2","article-title":"Organ cross talk and remote organ damage following acute kidney injury","volume":"46","author":"Ologunde","year":"2014","journal-title":"Int Urol Nephrol"},{"key":"10.1016\/j.kint.2018.10.020_bib6","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1016\/j.jacc.2008.07.051","article-title":"Cardiorenal syndrome","volume":"52","author":"Ronco","year":"2008","journal-title":"J\u00a0Am Coll Cardiol"},{"key":"10.1016\/j.kint.2018.10.020_bib7","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1007\/s10741-010-9223-1","article-title":"Epidemiology and outcome of the cardio-renal syndrome","volume":"16","author":"Cruz","year":"2011","journal-title":"Heart Fail Rev"},{"key":"10.1016\/j.kint.2018.10.020_bib8","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1038\/ncpneph0803","article-title":"Cardiorenal and renocardiac syndromes: the need for a comprehensive classification and consensus","volume":"4","author":"Ronco","year":"2008","journal-title":"Nat Clin Pract Nephrol"},{"key":"10.1016\/j.kint.2018.10.020_bib9","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1186\/s13054-014-0492-2","article-title":"Three-year risk of cardiovascular disease among intensive care patients with acute kidney injury: a population-based cohort study","volume":"18","author":"Gammelager","year":"2014","journal-title":"Crit Care"},{"key":"10.1016\/j.kint.2018.10.020_bib10","doi-asserted-by":"crossref","first-page":"2886","DOI":"10.1681\/ASN.2006010063","article-title":"Increase in creatinine and cardiovascular risk in patients with systolic dysfunction after myocardial infarction","volume":"17","author":"Jose","year":"2006","journal-title":"J\u00a0Am Soc Nephrol"},{"key":"10.1016\/j.kint.2018.10.020_bib11","doi-asserted-by":"crossref","first-page":"448","DOI":"10.2215\/CJN.02440213","article-title":"Association between AKI and long-term renal and cardiovascular outcomes in United States Veterans","volume":"9","author":"Chawla","year":"2014","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.kint.2018.10.020_bib12","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1097\/01.ASN.0000130340.93930.DD","article-title":"Minimal changes of serum creatinine predict prognosis in patients after cardiothoracic surgery: a prospective cohort study","volume":"15","author":"Lassnigg","year":"2004","journal-title":"J\u00a0Am Soc Nephrol"},{"key":"10.1016\/j.kint.2018.10.020_bib13","doi-asserted-by":"crossref","first-page":"19","DOI":"10.2215\/CJN.00240605","article-title":"Acute kidney injury associated with cardiac surgery","volume":"1","author":"Rosner","year":"2006","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.kint.2018.10.020_bib14","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1016\/j.athoracsur.2017.01.019","article-title":"Renal failure after cardiac operations: not all acute kidney injury is the same","volume":"104","author":"Crawford","year":"2017","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.kint.2018.10.020_bib15","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/S0002-9343(97)00150-2","article-title":"Acute renal failure after coronary intervention: incidence, risk factors, and relationship to mortality","volume":"103","author":"McCullough","year":"1997","journal-title":"Am J Med"},{"key":"10.1016\/j.kint.2018.10.020_bib16","doi-asserted-by":"crossref","first-page":"2259","DOI":"10.1161\/01.CIR.0000016043.87291.33","article-title":"Incidence and prognostic importance of acute renal failure after percutaneous coronary intervention","volume":"105","author":"Rihal","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.kint.2018.10.020_bib17","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1097\/01.ASN.0000064946.94590.46","article-title":"Distant effects of experimental renal ischemia\/reperfusion injury","volume":"14","author":"Kelly","year":"2003","journal-title":"J\u00a0Am Soc Nephrol"},{"key":"10.1016\/j.kint.2018.10.020_bib18","doi-asserted-by":"crossref","first-page":"2378","DOI":"10.1681\/ASN.2014080750","article-title":"Regulation of mitochondrial dynamics by dynamin-related protein-1 in acute cardiorenal syndrome","volume":"26","author":"Sumida","year":"2015","journal-title":"J\u00a0Am Soc Nephrol"},{"key":"10.1016\/j.kint.2018.10.020_bib19","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.semnephrol.2005.09.003","article-title":"Acute renal failure: much more than a kidney disease","volume":"26","author":"Kelly","year":"2006","journal-title":"Semin Nephrol"},{"key":"10.1016\/j.kint.2018.10.020_bib20","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1161\/CIRCRESAHA.113.300376","article-title":"Cardiac metabolism in heart failure:\u00a0implications beyond ATP production","volume":"113","author":"Doenst","year":"2013","journal-title":"Circ Res"},{"key":"10.1016\/j.kint.2018.10.020_bib21","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1161\/CIRCHEARTFAILURE.114.001151","article-title":"Metabolomic analysis of pressure-overloaded and infarcted mouse hearts","volume":"7","author":"Sansbury","year":"2014","journal-title":"Circ Heart Fail"},{"key":"10.1016\/j.kint.2018.10.020_bib22","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1536\/ihj.16-432","article-title":"Metabolic characterization of myocardial infarction using GC-MS-based tissue metabolomics","volume":"58","author":"Wang","year":"2017","journal-title":"Int Heart J"},{"key":"10.1016\/j.kint.2018.10.020_bib23","doi-asserted-by":"crossref","first-page":"e3337","DOI":"10.1371\/journal.pntd.0003337","article-title":"Global metabolomic profiling of acute myocarditis caused by Trypanosoma cruzi infection","volume":"8","author":"Girones","year":"2014","journal-title":"PLoS Negl Trop Dis"},{"key":"10.1016\/j.kint.2018.10.020_bib24","first-page":"H1063","article-title":"Changes in myocardial concentration of glutamate and aspartate during coronary artery surgery","volume":"272","author":"Suleiman","year":"1997","journal-title":"Am J Physiol"},{"key":"10.1016\/j.kint.2018.10.020_bib25","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1258\/ebm.2012.012025","article-title":"Amino acids as metabolic substrates during cardiac ischemia","volume":"237","author":"Drake","year":"2012","journal-title":"Exp Biol Med (Maywood)"},{"key":"10.1016\/j.kint.2018.10.020_bib26","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/s11010-009-0101-x","article-title":"The importance of myocardial amino acids during ischemia and reperfusion in dilated left ventricle of patients with degenerative mitral valve disease","volume":"330","author":"Venturini","year":"2009","journal-title":"Mol Cell Biochem"},{"key":"10.1016\/j.kint.2018.10.020_bib27","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1038\/nature13909","article-title":"Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS","volume":"515","author":"Chouchani","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.kint.2018.10.020_bib28","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.yjmcc.2013.02.008","article-title":"Global metabolomic analysis of heart tissue in a hamster model for dilated cardiomyopathy","volume":"59","author":"Maekawa","year":"2013","journal-title":"J\u00a0Mol Cell Cardiol"},{"key":"10.1016\/j.kint.2018.10.020_bib29","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/j.yjmcc.2007.06.010","article-title":"Neutral sphingomyelinase inhibition participates to the benefits of N-acetylcysteine treatment in post-myocardial infarction failing heart rats","volume":"43","author":"Adamy","year":"2007","journal-title":"J\u00a0Mol Cell Cardiol"},{"key":"10.1016\/j.kint.2018.10.020_bib30","doi-asserted-by":"crossref","first-page":"e4871","DOI":"10.1371\/journal.pone.0004871","article-title":"Glutathione deficiency in cardiac patients is related to the functional status and structural cardiac abnormalities","volume":"4","author":"Damy","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.kint.2018.10.020_bib31","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1042\/BJ20061645","article-title":"2-aminoadipic acid is a marker of protein carbonyl oxidation in the aging human skin: effects of diabetes, renal failure and sepsis","volume":"404","author":"Sell","year":"2007","journal-title":"Biochem J"},{"key":"10.1016\/j.kint.2018.10.020_bib32","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S1471-4914(03)00031-5","article-title":"Protein carbonylation in human diseases","volume":"9","author":"Dalle-Donne","year":"2003","journal-title":"Trends Mol Med"},{"key":"10.1016\/j.kint.2018.10.020_bib33","doi-asserted-by":"crossref","first-page":"23457","DOI":"10.1074\/jbc.M703211200","article-title":"Structural and functional basis for (S)-allantoin formation in the ureide pathway","volume":"282","author":"Kim","year":"2007","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.kint.2018.10.020_bib34","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.ab.2010.03.033","article-title":"Allantoin in human urine quantified by ultra-performance liquid chromatography-tandem mass spectrometry","volume":"402","author":"Tolun","year":"2010","journal-title":"Anal Biochem"},{"key":"10.1016\/j.kint.2018.10.020_bib35","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1038\/sj.bjp.0705776","article-title":"Measuring reactive species and oxidative damage in\u00a0vivo and in cell culture: how should you do it and what do the results mean?","volume":"142","author":"Halliwell","year":"2004","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.kint.2018.10.020_bib36","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1042\/bj2430803","article-title":"Measurement of allantoin and uric acid in human body fluids. A potential index of free-radical reactions in\u00a0vivo?","volume":"243","author":"Grootveld","year":"1987","journal-title":"Biochem J"},{"key":"10.1016\/j.kint.2018.10.020_bib37","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/0009-2797(90)90006-9","article-title":"Action of biologically-relevant oxidizing species upon uric acid. Identification of uric acid oxidation products","volume":"73","author":"Kaur","year":"1990","journal-title":"Chem Biol Interact"},{"key":"10.1016\/j.kint.2018.10.020_bib38","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1023\/A:1015380609464","article-title":"Energy metabolism in the hypertrophied heart","volume":"7","author":"Sambandam","year":"2002","journal-title":"Heart Fail Rev"},{"key":"10.1016\/j.kint.2018.10.020_bib39","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1002\/j.2040-4603.2016.tb00680.x","article-title":"Glucose transporters in cardiac metabolism and hypertrophy","volume":"6","author":"Shao","year":"2015","journal-title":"Compr Physiol"},{"key":"10.1016\/j.kint.2018.10.020_bib40","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1161\/01.RES.0000137170.41939.d9","article-title":"Is the failing heart energy starved? On using chemical energy to support cardiac function","volume":"95","author":"Ingwall","year":"2004","journal-title":"Circ Res"},{"key":"10.1016\/j.kint.2018.10.020_bib41","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1136\/hrt.64.6.359","article-title":"Excess purine degradation caused by an imbalance in the supply of adenosine triphosphate in patients with congestive heart failure","volume":"64","author":"Hisatome","year":"1990","journal-title":"Br Heart J"},{"key":"10.1016\/j.kint.2018.10.020_bib42","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1016\/S0002-9149(77)80212-9","article-title":"Ischemic contracture of the myocardium: mechanisms and prevention","volume":"39","author":"Hearse","year":"1977","journal-title":"Am J Cardiol"},{"key":"10.1016\/j.kint.2018.10.020_bib43","doi-asserted-by":"crossref","first-page":"e0184764","DOI":"10.1371\/journal.pone.0184764","article-title":"Association between E\/e ratio and fluid overload in patients with predialysis chronic kidney disease","volume":"12","author":"Kim","year":"2017","journal-title":"PLoS One"},{"key":"10.1016\/j.kint.2018.10.020_bib44","doi-asserted-by":"crossref","first-page":"C967","DOI":"10.1152\/ajpcell.1990.258.6.C967","article-title":"Effects of changes of pH on the contractile function of cardiac muscle","volume":"258","author":"Orchard","year":"1990","journal-title":"Am J Physiol"},{"key":"10.1016\/j.kint.2018.10.020_bib45","doi-asserted-by":"crossref","first-page":"2109","DOI":"10.1006\/jmcc.2000.1474","article-title":"Glutamate-loading stimulates metabolic flux and improves cell recovery following chemical hypoxia in isolated cardiomyocytes","volume":"33","author":"Williams","year":"2001","journal-title":"J\u00a0Mol Cell Cardiol"},{"key":"10.1016\/j.kint.2018.10.020_bib46","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1038\/cdd.2009.107","article-title":"Apoptosis and glutathione: beyond an antioxidant","volume":"16","author":"Franco","year":"2009","journal-title":"Cell Death Differ"},{"key":"10.1016\/j.kint.2018.10.020_bib47","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1016\/j.cell.2016.02.006","article-title":"EGLN1 inhibition and rerouting of alpha-ketoglutarate suffice for remote ischemic protection","volume":"164","author":"Olenchock","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.kint.2018.10.020_bib48","doi-asserted-by":"crossref","first-page":"861","DOI":"10.2215\/CJN.12191111","article-title":"Ongoing clinical trials in AKI","volume":"7","author":"Faubel","year":"2012","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.kint.2018.10.020_bib49","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1038\/ki.2008.314","article-title":"Interleukin-6 mediates lung injury following ischemic acute kidney injury or bilateral nephrectomy","volume":"74","author":"Klein","year":"2008","journal-title":"Kidney Int"},{"key":"10.1016\/j.kint.2018.10.020_bib50","doi-asserted-by":"crossref","first-page":"R1034","DOI":"10.1152\/ajpregu.00030.2015","article-title":"Early hemorrhage triggers metabolic responses that build up during prolonged shock","volume":"308","author":"D'Alessandro","year":"2015","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.kint.2018.10.020_bib51","doi-asserted-by":"crossref","DOI":"10.1002\/cpbi.11","article-title":"Using MetaboAnalyst 3.0 for comprehensive metabolomics data analysis","volume":"55","author":"Xia","year":"2016","journal-title":"Curr Protoc Bioinformatics"},{"key":"10.1016\/j.kint.2018.10.020_bib52","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1186\/1471-2164-7-142","article-title":"Centering, scaling, and transformations: improving the biological information content of metabolomics data","volume":"7","author":"van den Berg","year":"2006","journal-title":"BMC Genomics"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253818308214?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253818308214?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T00:51:51Z","timestamp":1758761511000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253818308214"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3]]},"references-count":52,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["S0085253818308214"],"URL":"https:\/\/doi.org\/10.1016\/j.kint.2018.10.020","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[2019,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Metabolomics assessment reveals oxidative stress and altered energy production in the heart after ischemic acute kidney injury in mice","name":"articletitle","label":"Article Title"},{"value":"Kidney International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.kint.2018.10.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 International Society of Nephrology. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}