{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T02:50:50Z","timestamp":1790823050322,"version":"4.1.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,10,7]],"date-time":"2023-10-07T00:00:00Z","timestamp":1696636800000},"content-version":"vor","delay-in-days":1467,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["kidney-international.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[2019,10]]},"DOI":"10.1016\/j.kint.2019.05.027","type":"journal-article","created":{"date-parts":[[2019,6,25]],"date-time":"2019-06-25T12:36:34Z","timestamp":1561466194000},"page":"1005-1009","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":59,"title":["The sensitivity and specificity of the routine kidney biopsy immunofluorescence panel are inferior to diagnosing renal immunoglobulin-derived amyloidosis by mass spectrometry"],"prefix":"10.1016","volume":"96","author":[{"given":"Maria L.","family":"Gonzalez Suarez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pingchuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samih H.","family":"Nasr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Insara Jaffer","family":"Sathick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wonngarm","family":"Kittanamongkolchai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul J.","family":"Kurtin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariam P.","family":"Alexander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn D.","family":"Cornell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary E.","family":"Fidler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph P.","family":"Grande","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loren P.","family":"Herrera Hernandez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samar M.","family":"Said","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjeev","family":"Sethi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Dispenzieri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morie A.","family":"Gertz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nelson","family":"Leung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.kint.2019.05.027_bib1","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1056\/NEJM198006053022305","article-title":"Amyloid deposits and amyloidosis. The beta-fibrilloses (first of two parts)","volume":"302","author":"Glenner","year":"1980","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.kint.2019.05.027_bib2","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1182\/blood.V79.7.1817.1817","article-title":"Incidence and natural history of primary systemic amyloidosis in Olmsted County, Minnesota, 1950 through 1989","volume":"79","author":"Kyle","year":"1992","journal-title":"Blood"},{"key":"10.1016\/j.kint.2019.05.027_bib3","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1056\/NEJM199709253371306","article-title":"The systemic amyloidoses","volume":"337","author":"Falk","year":"1997","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.kint.2019.05.027_bib4","doi-asserted-by":"crossref","first-page":"3458","DOI":"10.1681\/ASN.2006050460","article-title":"Amyloidosis-associated kidney disease","volume":"17","author":"Dember","year":"2006","journal-title":"J\u00a0Am Soc Nephrol"},{"key":"10.1016\/j.kint.2019.05.027_bib5","first-page":"770","article-title":"Systemic amyloidosis: novel therapies and role of biomarkers","volume":"32","author":"Nuvolone","year":"2017","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.kint.2019.05.027_bib6","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/S0889-8588(18)30347-2","article-title":"Mechanisms of disease: monoclonal immunoglobulin deposition. Amyloidosis, light chain deposition disease, and light and heavy chain deposition disease","volume":"6","author":"Buxbaum","year":"1992","journal-title":"Hematol Oncol Clin North Am"},{"key":"10.1016\/j.kint.2019.05.027_bib7","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1080\/13506129.2018.1549825","article-title":"Amyloid nomenclature 2018: recommendations by the International Society of Amyloidosis (ISA) nomenclature committee","volume":"25","author":"Benson","year":"2018","journal-title":"Amyloid"},{"key":"10.1016\/j.kint.2019.05.027_bib8","doi-asserted-by":"crossref","first-page":"1798","DOI":"10.1016\/j.humpath.2007.04.013","article-title":"Clinical and histological characteristics of renal AA amyloidosis: a retrospective study of 68 cases with a special interest to amyloid-associated inflammatory response","volume":"38","author":"Verine","year":"2007","journal-title":"Hum Pathol"},{"key":"10.1016\/j.kint.2019.05.027_bib9","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1093\/ndt\/gfm684","article-title":"Renal involvement in systemic amyloidosis: an Italian collaborative study on survival and renal outcome","volume":"23","author":"Bergesio","year":"2008","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.kint.2019.05.027_bib10","doi-asserted-by":"crossref","first-page":"4957","DOI":"10.1182\/blood-2009-07-230722","article-title":"Classification of amyloidosis by laser microdissection and mass spectrometry-based proteomic analysis in clinical biopsy specimens","volume":"114","author":"Vrana","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.kint.2019.05.027_bib11","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1093\/ndt\/gfv018","article-title":"Disappearance of immunoglobulins from persistent renal amyloid deposits following stem cell transplantation for heavy-and light-chain amyloidosis","volume":"30","author":"Safadi","year":"2015","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.kint.2019.05.027_bib12","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1097\/PAS.0b013e3181abdfa7","article-title":"Prevalence and origin of amyloid in kidney biopsies","volume":"33","author":"von Hutten","year":"2009","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.kint.2019.05.027_bib13","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1038\/ki.2012.108","article-title":"Laser microdissection and mass spectrometry-based proteomics aids the diagnosis and typing of renal amyloidosis","volume":"82","author":"Sethi","year":"2012","journal-title":"Kidney Int"},{"key":"10.1016\/j.kint.2019.05.027_bib14","doi-asserted-by":"crossref","first-page":"917","DOI":"10.5858\/2007-131-917-TOAIRB","article-title":"Typing of amyloidosis in renal biopsies: diagnostic pitfalls","volume":"131","author":"Satoskar","year":"2007","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.kint.2019.05.027_bib15","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1038\/ki.2012.414","article-title":"The diagnosis and characteristics of renal heavy-chain and heavy\/light-chain amyloidosis and their comparison with renal light-chain amyloidosis","volume":"83","author":"Nasr","year":"2013","journal-title":"Kidney Int"},{"key":"10.1016\/j.kint.2019.05.027_bib16","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.2215\/CJN.10491012","article-title":"Renal amyloidosis: origin and clinicopathologic correlations of 474 recent cases","volume":"8","author":"Said","year":"2013","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.kint.2019.05.027_bib17","doi-asserted-by":"crossref","first-page":"3050","DOI":"10.1093\/ndt\/gfh503","article-title":"AL-amyloidosis is underdiagnosed in renal biopsies","volume":"19","author":"Novak","year":"2004","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.kint.2019.05.027_bib18","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1038\/ki.2013.558","article-title":"Characterization and outcomes of renal leukocyte chemotactic factor 2-associated amyloidosis","volume":"86","author":"Said","year":"2014","journal-title":"Kidney Int"},{"key":"10.1016\/j.kint.2019.05.027_bib19","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1159\/000096765","article-title":"Immunoglobulin light and heavy chain amyloidosis AL\/AH: renal pathology and differential diagnosis","volume":"153","author":"Picken","year":"2007","journal-title":"Contrib Nephrol"},{"key":"10.1016\/j.kint.2019.05.027_bib20","doi-asserted-by":"crossref","first-page":"3206","DOI":"10.1182\/blood-2012-03-413682","article-title":"How I treat amyloidosis: the importance of accurate diagnosis and amyloid typing","volume":"120","author":"Leung","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.kint.2019.05.027_bib21","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1111\/bjh.13156","article-title":"Guidelines on the diagnosis and investigation of AL amyloidosis","volume":"168","author":"Gillmore","year":"2015","journal-title":"Br J Haematol"},{"key":"10.1016\/j.kint.2019.05.027_bib22","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1146\/annurev-pathol-052016-100200","article-title":"Amyloidosis: insights from proteomics","volume":"12","author":"Dogan","year":"2017","journal-title":"Annu Rev Pathol"},{"key":"10.1016\/j.kint.2019.05.027_bib23","doi-asserted-by":"crossref","first-page":"2180","DOI":"10.2215\/CJN.02890310","article-title":"Mass spectrometry-based proteomic diagnosis of renal immunoglobulin heavy chain amyloidosis","volume":"5","author":"Sethi","year":"2010","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.kint.2019.05.027_bib24","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/s12014-016-9133-x","article-title":"Implementation and evaluation of amyloidosis subtyping by laser-capture microdissection and tandem mass spectrometry","volume":"13","author":"Mollee","year":"2016","journal-title":"Clin Proteomics"},{"key":"10.1016\/j.kint.2019.05.027_bib25","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1136\/jclinpath-2014-202722","article-title":"A\u00a0comparison of immunohistochemistry and mass spectrometry for determining the amyloid fibril protein from formalin-fixed biopsy tissue","volume":"68","author":"Gilbertson","year":"2015","journal-title":"J\u00a0Clin Pathol"},{"key":"10.1016\/j.kint.2019.05.027_bib26","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1093\/ckj\/sfv087","article-title":"Proteomics and mass spectrometry in the diagnosis of renal amyloidosis","volume":"8","author":"Picken","year":"2015","journal-title":"Clin Kidney J"},{"key":"10.1016\/j.kint.2019.05.027_bib27","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1182\/blood-2011-06-358507","article-title":"Immunohistochemistry in the classification of systemic forms of amyloidosis: a systematic investigation of 117 patients","volume":"119","author":"Schonland","year":"2012","journal-title":"Blood"},{"key":"10.1016\/j.kint.2019.05.027_bib28","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1002\/pmic.200700426","article-title":"A\u00a0label-free quantification method by MS\/MS TIC compared to SILAC and spectral counting in a proteomics screen","volume":"8","author":"Asara","year":"2008","journal-title":"Proteomics"},{"key":"10.1016\/j.kint.2019.05.027_bib29","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/j.kint.2016.04.003","article-title":"Clinical, biopsy, and mass spectrometry characteristics of renal apolipoprotein A-IV amyloidosis","volume":"90","author":"Dasari","year":"2016","journal-title":"Kidney Int"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253819306118?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253819306118?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T00:54:40Z","timestamp":1758761680000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253819306118"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10]]},"references-count":29,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["S0085253819306118"],"URL":"https:\/\/doi.org\/10.1016\/j.kint.2019.05.027","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[2019,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The sensitivity and specificity of the routine kidney biopsy immunofluorescence panel are inferior to diagnosing renal immunoglobulin-derived amyloidosis by mass spectrometry","name":"articletitle","label":"Article Title"},{"value":"Kidney International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.kint.2019.05.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 International Society of Nephrology. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}