{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T19:53:26Z","timestamp":1792180406079,"version":"4.4.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,5,1]],"date-time":"2020-05-01T00:00:00Z","timestamp":1588291200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,3,20]],"date-time":"2020-03-20T00:00:00Z","timestamp":1584662400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81670633"],"award-info":[{"award-number":["81670633"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81470948"],"award-info":[{"award-number":["81470948"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81570667"],"award-info":[{"award-number":["81570667"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["91742204"],"award-info":[{"award-number":["91742204"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100015640","name":"Tongji Hospital","doi-asserted-by":"publisher","award":["TJ-C20200132"],"award-info":[{"award-number":["TJ-C20200132"]}],"id":[{"id":"10.13039\/501100015640","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2016YFC0906103"],"award-info":[{"award-number":["2016YFC0906103"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2015BAI12B07"],"award-info":[{"award-number":["2015BAI12B07"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2018YFC1314003-1"],"award-info":[{"award-number":["2018YFC1314003-1"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["kidney-international.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[2020,5]]},"DOI":"10.1016\/j.kint.2020.03.005","type":"journal-article","created":{"date-parts":[[2020,3,19]],"date-time":"2020-03-19T21:02:56Z","timestamp":1584651776000},"page":"829-838","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2125,"title":["Kidney disease is associated with in-hospital death of patients with COVID-19"],"prefix":"10.1016","volume":"97","author":[{"given":"Yichun","family":"Cheng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ran","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhixiang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junhua","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuwang","family":"Ge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.kint.2020.03.005_bib1","doi-asserted-by":"crossref","unstructured":"Li Q, Guan X, Wu P, et\u00a0al. Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. N Engl J Med. 2020;382:1199\u20131207.","DOI":"10.1056\/NEJMoa2001316"},{"key":"10.1016\/j.kint.2020.03.005_bib2","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1056\/NEJMoa2001017","article-title":"A\u00a0novel coronavirus from patients with pneumonia in China, 2019","volume":"382","author":"Zhu","year":"2020","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.kint.2020.03.005_bib3","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/S0140-6736(20)30251-8","article-title":"Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding","volume":"395","author":"Lu","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.kint.2020.03.005_bib4","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0140-6736(20)30183-5","article-title":"Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China","volume":"395","author":"Huang","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.kint.2020.03.005_bib5","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1111\/j.1523-1755.2005.67130.x","article-title":"Acute renal impairment in coronavirus-associated severe acute respiratory syndrome","volume":"67","author":"Chu","year":"2005","journal-title":"Kidney Int"},{"key":"10.1016\/j.kint.2020.03.005_bib6","doi-asserted-by":"crossref","first-page":"1977","DOI":"10.1056\/NEJMoa030666","article-title":"A\u00a0cluster of cases of severe acute respiratory syndrome in Hong Kong","volume":"48","author":"Tsang","year":"2003","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.kint.2020.03.005_bib7","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/S0140-6736(20)30211-7","article-title":"Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study","volume":"395","author":"Chen","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.kint.2020.03.005_bib8","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1038\/nrneph.2013.44","article-title":"Immune cell dysfunction and inflammation in end-stage renal disease","volume":"9","author":"Betjes","year":"2013","journal-title":"Nat Rev Nephrol"},{"key":"10.1016\/j.kint.2020.03.005_bib9","first-page":"557","article-title":"Upper respiratory tract infection among dialysis patients","volume":"18","author":"Cohen-Hagai","year":"2016","journal-title":"Isr Med Assoc J"},{"key":"10.1016\/j.kint.2020.03.005_bib10","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1186\/s12882-016-0412-6","article-title":"The clinical and economic burden of pneumonia in patients enrolled in Medicare receiving dialysis: a retrospective, observational cohort study","volume":"17","author":"Sibbel","year":"2016","journal-title":"BMC Nephrol"},{"key":"10.1016\/j.kint.2020.03.005_bib11","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/j.jcrc.2011.02.012","article-title":"Acute kidney injury in critically ill patients with pandemic influenza A pneumonia 2009 in Korea: a multicenter study","volume":"26","author":"Jung","year":"2011","journal-title":"J\u00a0Crit Care"},{"key":"10.1016\/j.kint.2020.03.005_bib12","doi-asserted-by":"crossref","first-page":"2139","DOI":"10.1016\/S0140-6736(17)31329-6","article-title":"Management of patients at risk of acute kidney injury","volume":"389","author":"Vanmassenhove","year":"2017","journal-title":"Lancet"},{"key":"10.1016\/j.kint.2020.03.005_bib13","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1001\/jama.2020.1585","article-title":"Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China","volume":"323","author":"Wang","year":"2020","journal-title":"JAMA"},{"key":"10.1016\/j.kint.2020.03.005_bib14","doi-asserted-by":"crossref","unstructured":"Guan W-J, Ni Z-Y, Hu Y, et\u00a0al. Clinical characteristics of coronavirus disease 2019 in China [e-pub ahead of print]. N Engl J Med. https:\/\/doi.org\/10.1056\/NEJMoa2002032. Accessed March 14, 2020.","DOI":"10.1056\/NEJMoa2002032"},{"key":"10.1016\/j.kint.2020.03.005_bib15","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1186\/s12882-016-0351-2","article-title":"Epidemiology and outcomes of acute kidney injury in elderly Chinese patients: a subgroup analysis from the EACH study","volume":"17","author":"Ge","year":"2016","journal-title":"BMC Nephrol"},{"key":"10.1016\/j.kint.2020.03.005_bib16","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1016\/S0140-6736(15)00344-X","article-title":"Acute kidney injury in China: a cross-sectional survey","volume":"386","author":"Yang","year":"2015","journal-title":"Lancet"},{"key":"10.1016\/j.kint.2020.03.005_bib17","doi-asserted-by":"crossref","first-page":"1510","DOI":"10.2215\/CJN.02140215","article-title":"Epidemiology and clinical correlates of AKI in Chinese hospitalized adults","volume":"10","author":"Xu","year":"2015","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.kint.2020.03.005_bib18","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1016\/S0140-6736(03)13412-5","article-title":"Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study","volume":"361","author":"Peiris","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.kint.2020.03.005_bib19","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1038\/s41586-020-2012-7","article-title":"A\u00a0pneumonia outbreak associated with a new coronavirus of\u00a0probable bat origin","volume":"579","author":"Zhou","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.kint.2020.03.005_bib20","author":"Li"},{"key":"10.1016\/j.kint.2020.03.005_bib21","doi-asserted-by":"crossref","first-page":"1872","DOI":"10.1001\/jama.2009.1496","article-title":"Critically ill patients with 2009 influenza A(H1N1) infection in Canada","volume":"302","author":"Kumar","year":"2009","journal-title":"JAMA"},{"key":"10.1016\/j.kint.2020.03.005_bib22","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/S0140-6736(20)30317-2","article-title":"Clinical evidence does not support corticosteroid treatment for 2019-nCoV lung injury","volume":"395","author":"Russell","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.kint.2020.03.005_bib23","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/S0140-6736(20)30361-5","article-title":"On the use of corticosteroids for 2019-nCoV pneumonia","volume":"395","author":"Shang","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.kint.2020.03.005_bib24","doi-asserted-by":"crossref","unstructured":"Zheng YY, Ma YT, Zhang JY, Xie X. COVID-19 and the cardiovascular system [e-pub ahead of print]. Nat Rev Cardiol. https:\/\/doi.org\/10.1038\/s41569-020-0360-5. Accessed March 14, 2020.","DOI":"10.1038\/s41569-020-0360-5"},{"key":"10.1016\/j.kint.2020.03.005_bib25","doi-asserted-by":"crossref","first-page":"604","DOI":"10.7326\/0003-4819-150-9-200905050-00006","article-title":"CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration): a new equation to estimate glomerular filtration rate","volume":"150","author":"Levey","year":"2009","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.kint.2020.03.005_bib26","first-page":"1","article-title":"KDIGO clinical practice guideline for Acute Kidney Injury","volume":"2","year":"2012","journal-title":"Kidney Int Suppl"},{"key":"10.1016\/j.kint.2020.03.005_bib27","author":"Guan"},{"key":"10.1016\/j.kint.2020.03.005_bib28","author":"Tan"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253820302556?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253820302556?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T14:54:25Z","timestamp":1777474465000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253820302556"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5]]},"references-count":28,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,5]]}},"alternative-id":["S0085253820302556"],"URL":"https:\/\/doi.org\/10.1016\/j.kint.2020.03.005","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2020.02.18.20023242","asserted-by":"object"}]},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[2020,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Kidney disease is associated with in-hospital death of patients with COVID-19","name":"articletitle","label":"Article Title"},{"value":"Kidney International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.kint.2020.03.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 International Society of Nephrology. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}