{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T11:59:28Z","timestamp":1784116768866,"version":"3.55.0"},"reference-count":15,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["kidney-international.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[2025,5]]},"DOI":"10.1016\/j.kint.2024.10.029","type":"journal-article","created":{"date-parts":[[2025,4,18]],"date-time":"2025-04-18T05:06:15Z","timestamp":1744952775000},"page":"796-799","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Using donor-derived cell-free DNA in kidney transplant patients: this jury needs more evidence"],"prefix":"10.1016","volume":"107","author":[{"given":"Nay","family":"Seif","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4783-7775","authenticated-orcid":false,"given":"Roy D.","family":"Bloom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.kint.2024.10.029_bib1","doi-asserted-by":"crossref","first-page":"2652","DOI":"10.1111\/ajt.15937","article-title":"Sensitization in transplantation: assessment of risk (STAR) 2019 Working Group Meeting Report","volume":"20","author":"Tambur","year":"2020","journal-title":"Am J Transplant"},{"key":"10.1016\/j.kint.2024.10.029_bib2","doi-asserted-by":"crossref","first-page":"2221","DOI":"10.1681\/ASN.2016091034","article-title":"Cell-free DNA and active rejection in kidney allografts","volume":"28","author":"Bloom","year":"2017","journal-title":"J\u00a0Am Soc Nephrol"},{"key":"10.1016\/j.kint.2024.10.029_bib3","doi-asserted-by":"crossref","first-page":"e379","DOI":"10.1097\/TXD.0000000000000821","article-title":"Donor-derived cell-free DNA identifies antibody-mediated rejection in donor specific antibody positive kidney transplant recipients","volume":"4","author":"Jordan","year":"2018","journal-title":"Transplant Direct"},{"key":"10.1016\/j.kint.2024.10.029_bib4","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1016\/j.kint.2021.11.034","article-title":"Clinical outcomes from the Assessing Donor-derived cell-free DNA Monitoring Insights of kidney Allografts with Longitudinal surveillance (ADMIRAL) study","volume":"101","author":"Bu","year":"2022","journal-title":"Kidney Int"},{"key":"10.1016\/j.kint.2024.10.029_bib5","doi-asserted-by":"crossref","first-page":"1994","DOI":"10.1097\/TP.0000000000005007","article-title":"Elevation of donor-derived cell-free DNA before biopsy-proven rejection in kidney transplant","volume":"108","author":"Bromberg","year":"2024","journal-title":"Transplantation"},{"key":"10.1016\/j.kint.2024.10.029_bib6","doi-asserted-by":"crossref","first-page":"2320","DOI":"10.1038\/s41591-024-03087-3","article-title":"Cell-free DNA for the detection of kidney allograft rejection","volume":"30","author":"Aubert","year":"2024","journal-title":"Nat Med"},{"key":"10.1016\/j.kint.2024.10.029_bib7","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1681\/ASN.2021091191","article-title":"The Trifecta Study: comparing plasma levels of donor-derived cell-free DNA with the molecular phenotype of kidney transplant biopsies","volume":"33","author":"Halloran","year":"2022","journal-title":"J\u00a0Am Soc Nephrol"},{"key":"10.1016\/j.kint.2024.10.029_bib8","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1097\/TP.0000000000004482","article-title":"Understanding donor-derived cell-free DNA in kidney transplantation: an overview and case-based guide for clinicians","volume":"107","author":"Graver","year":"2023","journal-title":"Transplantation"},{"key":"10.1016\/j.kint.2024.10.029_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.healun.2023.02.529","article-title":"(514) Clinical utility of donor derived cell-free DNA in the multiorgan transplantation","volume":"42","author":"Moeller","year":"2023","journal-title":"J\u00a0Heart Lung Transplant"},{"key":"10.1016\/j.kint.2024.10.029_bib10","doi-asserted-by":"crossref","DOI":"10.1111\/ctr.14101","article-title":"Impact of body mass index and recipient age on baseline donor-derived cell free DNA (dd-cfDNA) in kidney transplant recipients","volume":"34","author":"Sureshkumar","year":"2020","journal-title":"Clin Transplant"},{"key":"10.1016\/j.kint.2024.10.029_bib11","first-page":"1700","article-title":"The current state of donor-derived cell-free DNA use in allograft monitoring in kidney transplantation","volume":"12","author":"Kueht","year":"2022","journal-title":"J\u00a0Pers Med"},{"key":"10.1016\/j.kint.2024.10.029_bib12","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1097\/TP.0000000000005122","article-title":"Biomarkers in kidney transplantation: a rapidly evolving landscape","volume":"109","author":"Gupta","year":"2025","journal-title":"Transplantation"},{"key":"10.1016\/j.kint.2024.10.029_bib13","doi-asserted-by":"crossref","first-page":"e568","DOI":"10.1097\/TXD.0000000000001019","article-title":"Donor-derived cell-free DNA in infections in kidney transplant recipients: case series","volume":"6","author":"Goussous","year":"2020","journal-title":"Transplant Direct"},{"key":"10.1016\/j.kint.2024.10.029_bib14","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1111\/ajt.16150","article-title":"Economic analysis of screening for subclinical rejection in kidney transplantation using protocol biopsies and noninvasive biomarkers","volume":"21","author":"Puttarajappa","year":"2021","journal-title":"Am J Transplant"},{"key":"10.1016\/j.kint.2024.10.029_bib15","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1056\/NEJMoa2400763","article-title":"A\u00a0randomized phase 2 trial of felzartamab in antibody-mediated rejection","volume":"391","author":"Mayer","year":"2024","journal-title":"N\u00a0Engl J Med"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S008525382400807X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S008525382400807X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T04:24:58Z","timestamp":1777695898000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S008525382400807X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5]]},"references-count":15,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,5]]}},"alternative-id":["S008525382400807X"],"URL":"https:\/\/doi.org\/10.1016\/j.kint.2024.10.029","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[2025,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Using donor-derived cell-free DNA in kidney transplant patients: this jury needs more evidence","name":"articletitle","label":"Article Title"},{"value":"Kidney International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.kint.2024.10.029","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.kint.2025.01.039","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"https:\/\/doi.org\/10.1016\/j.kint.2024.09.023","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 International Society of Nephrology. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}