{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T02:44:23Z","timestamp":1787798663982,"version":"build-2784847793"},"reference-count":52,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T00:00:00Z","timestamp":1759968000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["431984000 - CRC 1453"],"award-info":[{"award-number":["431984000 - CRC 1453"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["EXC-2189"],"award-info":[{"award-number":["EXC-2189"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["428212052 - SPP 2177"],"award-info":[{"award-number":["428212052 - SPP 2177"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["390939984"],"award-info":[{"award-number":["390939984"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021729","name":"University of Freiburg Faculty of Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100021729","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["R01-DK136765"],"award-info":[{"award-number":["R01-DK136765"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["R01-DK105124"],"award-info":[{"award-number":["R01-DK105124"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["kidney-international.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.kint.2025.08.038","type":"journal-article","created":{"date-parts":[[2025,10,11]],"date-time":"2025-10-11T01:13:41Z","timestamp":1760145221000},"page":"365-378","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Genetic screens of imaging-derived kidney volumes identify genes linked to kidney function"],"prefix":"10.1016","volume":"109","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3341-5638","authenticated-orcid":false,"given":"Sara","family":"Monteiro-Martins","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oleg","family":"Borisov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atlas","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilfried","family":"Reichardt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Haug","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elias","family":"Kellner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Buechert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Ott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maximilian F.","family":"Russe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabian","family":"Bamberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krzysztof","family":"Kiryluk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2263-447X","authenticated-orcid":false,"given":"Peggy","family":"Sekula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Reisert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4671-3714","authenticated-orcid":false,"given":"Anna","family":"K\u00f6ttgen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.kint.2025.08.038_bib1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0158765","article-title":"Global prevalence of chronic kidney disease - a systematic review and meta-analysis","volume":"11","author":"Hill","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.kint.2025.08.038_bib2","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/S0140-6736(20)30045-3","article-title":"Global, regional, and national burden of chronic kidney disease, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017","volume":"395","year":"2020","journal-title":"Lancet"},{"issue":"4S","key":"10.1016\/j.kint.2025.08.038_bib3","first-page":"S117","article-title":"KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease","volume":"105","year":"2024","journal-title":"Kidney Int"},{"key":"10.1016\/j.kint.2025.08.038_bib4","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1038\/s41588-019-0407-x","article-title":"A catalog of genetic loci associated with kidney function from analyses of a million individuals","volume":"51","author":"Wuttke","year":"2019","journal-title":"Nat Genet"},{"key":"10.1016\/j.kint.2025.08.038_bib5","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1038\/s41588-022-01097-w","article-title":"Epigenomic and transcriptomic analyses define core cell types, genes and targetable mechanisms for kidney disease","volume":"54","author":"Liu","year":"2022","journal-title":"Nat Genet"},{"key":"10.1016\/j.kint.2025.08.038_bib6","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1038\/s41588-021-00931-x","article-title":"A cross-population atlas of genetic associations for 220 human phenotypes","volume":"53","author":"Sakaue","year":"2021","journal-title":"Nat Genet"},{"key":"10.1016\/j.kint.2025.08.038_bib7","article-title":"Genome-wide study investigating effector genes and polygenic prediction for kidney function in persons with ancestry from Africa and the Americas","volume":"4","author":"Hughes","year":"2024","journal-title":"Cell Genom"},{"key":"10.1016\/j.kint.2025.08.038_bib8","series-title":"Clinical Methods: The History, Physical, and Laboratory Examinations","year":"1990"},{"key":"10.1016\/j.kint.2025.08.038_bib9","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/s41586-018-0579-z","article-title":"The UK Biobank resource with deep phenotyping and genomic data","volume":"562","author":"Bycroft","year":"2018","journal-title":"Nature"},{"key":"10.1016\/j.kint.2025.08.038_bib10","doi-asserted-by":"crossref","first-page":"2624","DOI":"10.1038\/s41467-020-15948-9","article-title":"The UK Biobank imaging enhancement of 100,000 participants: rationale, data collection, management and future directions","volume":"11","author":"Littlejohns","year":"2020","journal-title":"Nat Commun"},{"key":"10.1016\/j.kint.2025.08.038_bib11","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1007\/s10654-022-00890-5","article-title":"Framework and baseline examination of the German National Cohort (NAKO)","volume":"37","author":"Peters","year":"2022","journal-title":"Eur J Epidemiol"},{"key":"10.1016\/j.kint.2025.08.038_bib12","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1148\/radiol.2015142272","article-title":"Whole-body MR imaging in the German national cohort: rationale, design, and technical background","volume":"277","author":"Bamberg","year":"2015","journal-title":"Radiology"},{"key":"10.1016\/j.kint.2025.08.038_bib13","first-page":"587","article-title":"Baseline MRI examination in the NAKO Health Study\u2014findings on feasibility, participation and dropout rates, comfort, and image quality","volume":"121","author":"Bamberg","year":"2024","journal-title":"Dtsch Arztebl Int"},{"key":"10.1016\/j.kint.2025.08.038_bib14","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.65554","article-title":"Genetic architecture of 11 organ traits derived from abdominal MRI using deep learning","volume":"10","author":"Liu","year":"2021","journal-title":"eLife"},{"key":"10.1016\/j.kint.2025.08.038_bib15","first-page":"284","article-title":"Imaging markers derived from MRI-based automated kidney segmentation","volume":"121","author":"Kellner","year":"2024","journal-title":"Dtsch Arztebl Int"},{"key":"10.1016\/j.kint.2025.08.038_bib16","author":"Reisert"},{"key":"10.1016\/j.kint.2025.08.038_bib17","series-title":"Medical Image Computing and Computer-Assisted Intervention \u2013 MICCAI 2016","first-page":"424","article-title":"3D U-Net: learning dense volumetric segmentation from sparse annotation","author":"\u00c7i\u00e7ek","year":"2016"},{"key":"10.1016\/j.kint.2025.08.038_bib18","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1038\/s41588-021-00870-7","article-title":"Computationally efficient whole-genome regression for quantitative and binary traits","volume":"53","author":"Mbatchou","year":"2021","journal-title":"Nat Genet"},{"key":"10.1016\/j.kint.2025.08.038_bib19","doi-asserted-by":"crossref","first-page":"2408","DOI":"10.1038\/s41588-025-02335-7","article-title":"Pan-UK Biobank genome-wide association analyses enhance discovery and resolution of ancestry-enriched effects","volume":"57","author":"Karczewski","year":"2025","journal-title":"Nat Genet"},{"key":"10.1016\/j.kint.2025.08.038_bib21","doi-asserted-by":"crossref","first-page":"e3","DOI":"10.1093\/nar\/gky837","article-title":"ProGeM: a framework for the prioritization of candidate causal genes at molecular quantitative trait loci","volume":"47","author":"Stacey","year":"2019","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.kint.2025.08.038_bib22","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1186\/s13059-016-0974-4","article-title":"The Ensembl variant effect predictor","volume":"17","author":"McLaren","year":"2016","journal-title":"Genome Biol"},{"key":"10.1016\/j.kint.2025.08.038_bib23","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1038\/ng833","article-title":"The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein","volume":"30","author":"Ward","year":"2002","journal-title":"Nat Genet"},{"key":"10.1016\/j.kint.2025.08.038_bib24","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1002\/humu.21610","article-title":"Two mutations in human BICC1 resulting in Wnt pathway hyperactivity associated with cystic renal dysplasia","volume":"33","author":"Kraus","year":"2012","journal-title":"Hum Mutat"},{"key":"10.1016\/j.kint.2025.08.038_bib25","doi-asserted-by":"crossref","first-page":"2749","DOI":"10.1242\/dev.120.10.2749","article-title":"Function of the retinoic acid receptors (RARs) during development (II): multiple abnormalities at various stages of organogenesis in RAR double mutants","volume":"120","author":"Mendelsohn","year":"1994","journal-title":"Development"},{"key":"10.1016\/j.kint.2025.08.038_bib26","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1038\/ng.3440","article-title":"Mutations in the transcriptional repressor REST predispose to Wilms tumor","volume":"47","author":"Mahamdallie","year":"2015","journal-title":"Nat Genet"},{"key":"10.1016\/j.kint.2025.08.038_bib27","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1126\/science.aaz1776","article-title":"The GTEx Consortium atlas of genetic regulatory effects across human tissues","volume":"369","year":"2020","journal-title":"Science"},{"key":"10.1016\/j.kint.2025.08.038_bib28","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1038\/s41588-021-00913-z","article-title":"Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression","volume":"53","author":"V\u00f5sa","year":"2021","journal-title":"Nat Genet"},{"key":"10.1016\/j.kint.2025.08.038_bib29","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1038\/s41586-023-06592-6","article-title":"Plasma proteomic associations with genetics and health in the UK Biobank","volume":"622","author":"Sun","year":"2023","journal-title":"Nature"},{"key":"10.1016\/j.kint.2025.08.038_bib30","doi-asserted-by":"crossref","first-page":"1712","DOI":"10.1038\/s41588-021-00978-w","article-title":"Large-scale integration of the plasma proteome with genetics and disease","volume":"53","author":"Ferkingstad","year":"2021","journal-title":"Nat Genet"},{"key":"10.1016\/j.kint.2025.08.038_bib31","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1053\/ajkd.2002.34487","article-title":"Serum cystatin C is superior to serum creatinine as a marker of kidney function: a meta-analysis","volume":"40","author":"Dharnidharka","year":"2002","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.kint.2025.08.038_bib32","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1053\/j.ajkd.2018.07.015","article-title":"Effects of intensive blood pressure lowering on kidney tubule injury in CKD: a longitudinal subgroup analysis in SPRINT","volume":"73","author":"Malhotra","year":"2019","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.kint.2025.08.038_bib33","article-title":"Circulating serum trefoil factor 3 (TFF3) is dramatically increased in chronic kidney disease","volume":"8","author":"Du T yi","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.kint.2025.08.038_bib34","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1046\/j.1523-1755.2002.00433.x","article-title":"Kidney injury molecule-1 (KIM-1): a novel biomarker for human renal proximal tubule injury","volume":"62","author":"Han","year":"2002","journal-title":"Kidney Int"},{"key":"10.1016\/j.kint.2025.08.038_bib35","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.kint.2019.10.027","article-title":"The CKDGen Consortium: ten years of insights into the genetic basis of kidney function","volume":"97","author":"K\u00f6ttgen","year":"2020","journal-title":"Kidney Int"},{"key":"10.1016\/j.kint.2025.08.038_bib36","doi-asserted-by":"crossref","first-page":"4130","DOI":"10.1038\/s41467-019-11576-0","article-title":"Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria","volume":"10","author":"Teumer","year":"2019","journal-title":"Nat Commun"},{"key":"10.1016\/j.kint.2025.08.038_bib37","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1038\/s41588-019-0504-x","article-title":"Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels","volume":"51","author":"Tin","year":"2019","journal-title":"Nat Genet"},{"key":"10.1016\/j.kint.2025.08.038_bib38","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1038\/s41586-021-03205-y","article-title":"Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program","volume":"590","author":"Taliun","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.kint.2025.08.038_bib39","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1038\/s41586-022-05473-8","article-title":"FinnGen provides genetic insights from a well-phenotyped isolated population","volume":"613","author":"Kurki","year":"2023","journal-title":"Nature"},{"key":"10.1016\/j.kint.2025.08.038_bib40","doi-asserted-by":"crossref","first-page":"2336","DOI":"10.1093\/bioinformatics\/btq419","article-title":"LocusZoom: regional visualization of genome-wide association scan results","volume":"26","author":"Pruim","year":"2010","journal-title":"Bioinformatics"},{"key":"10.1016\/j.kint.2025.08.038_bib41","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1007\/s00335-002-2241-0","article-title":"Positional cloning of jcpk\/bpk locus of the mouse","volume":"14","author":"Cogswell","year":"2003","journal-title":"Mamm Genome"},{"key":"10.1016\/j.kint.2025.08.038_bib42","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1681\/ASN.0000000000000419","article-title":"Kidney volume and risk of incident kidney outcomes","volume":"35","author":"Wu","year":"2024","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.kint.2025.08.038_bib43","doi-asserted-by":"crossref","first-page":"2027","DOI":"10.1681\/ASN.2007101098","article-title":"A common RET variant is associated with reduced newborn kidney size and function","volume":"19","author":"Zhang","year":"2008","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.kint.2025.08.038_bib44","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1038\/s41581-022-00668-8","article-title":"The impact of intrauterine growth restriction and prematurity on nephron endowment","volume":"19","author":"Sutherland","year":"2023","journal-title":"Nat Rev Nephrol"},{"key":"10.1016\/j.kint.2025.08.038_bib45","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/s10334-019-00773-z","article-title":"Renal sinus fat and renal hemodynamics: a cross-sectional analysis","volume":"33","author":"Spit","year":"2020","journal-title":"MAGMA"},{"key":"10.1016\/j.kint.2025.08.038_bib46","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1007\/s10157-023-02350-0","article-title":"Prognostic impact of renal sinus fat accumulation in patients with chronic kidney disease","volume":"27","author":"Fujioka","year":"2023","journal-title":"Clin Exp Nephrol"},{"key":"10.1016\/j.kint.2025.08.038_bib47","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/S0925-4773(00)00568-2","article-title":"Identification and expression of the mammalian homologue of bicaudal-C","volume":"101","author":"Wessely","year":"2001","journal-title":"Mech Dev"},{"key":"10.1016\/j.kint.2025.08.038_bib48","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1242\/dev.046045","article-title":"The RNA-binding protein bicaudal C regulates polycystin 2 in the kidney by antagonizing miR-17 activity","volume":"137","author":"Tran","year":"2010","journal-title":"Development"},{"key":"10.1016\/j.kint.2025.08.038_bib49","doi-asserted-by":"crossref","first-page":"3019","DOI":"10.1242\/dev.038174","article-title":"Bicaudal C, a novel regulator of Dvl signaling abutting RNA-processing bodies, controls cilia orientation and leftward flow","volume":"136","author":"Maisonneuve","year":"2009","journal-title":"Development"},{"key":"10.1016\/j.kint.2025.08.038_bib50","first-page":"96","article-title":"Knockdown of bicaudal C in zebrafish (Danio rerio) causes cystic kidneys: a nonmammalian model of polycystic kidney disease","volume":"60","author":"Bouvrette","year":"2010","journal-title":"Comp Med"},{"key":"10.1016\/j.kint.2025.08.038_bib51","doi-asserted-by":"crossref","first-page":"eadp4753","DOI":"10.1126\/science.adp4753","article-title":"Kidney multiome-based genetic scorecard reveals convergent coding and regulatory variants","volume":"387","author":"Liu","year":"2025","journal-title":"Science"},{"key":"10.1016\/j.kint.2025.08.038_bib52","doi-asserted-by":"crossref","DOI":"10.1126\/science.adj1182","article-title":"Diversity and scale: genetic architecture of 2068 traits in the VA Million Veteran Program","volume":"385","author":"Verma","year":"2024","journal-title":"Science"},{"key":"10.1016\/j.kint.2025.08.038_bib53","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1038\/s41588-018-0047-6","article-title":"Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases","volume":"50","author":"Kanai","year":"2018","journal-title":"Nat Genet"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253825007811?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253825007811?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,14]],"date-time":"2026-06-14T17:05:03Z","timestamp":1781456703000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253825007811"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":52,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["S0085253825007811"],"URL":"https:\/\/doi.org\/10.1016\/j.kint.2025.08.038","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Genetic screens of imaging-derived kidney volumes identify genes linked to kidney function","name":"articletitle","label":"Article Title"},{"value":"Kidney International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.kint.2025.08.038","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.kint.2025.12.003","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 International Society of Nephrology. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}