{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T22:14:56Z","timestamp":1792275296635,"version":"4.4.0"},"reference-count":34,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T00:00:00Z","timestamp":1774310400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000179","name":"Office of the Director","doi-asserted-by":"publisher","award":["3UM1HG008901-03S1"],"award-info":[{"award-number":["3UM1HG008901-03S1"]}],"id":[{"id":"10.13039\/100000179","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000051","name":"National Human Genome Research Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000051","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016477","name":"CareDx","doi-asserted-by":"publisher","award":["U01 AI152585-01"],"award-info":[{"award-number":["U01 AI152585-01"]}],"id":[{"id":"10.13039\/100016477","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["1ZIAHG200362"],"award-info":[{"award-number":["1ZIAHG200362"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000093","name":"Center for Information Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000093","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["U01DK100846"],"award-info":[{"award-number":["U01DK100846"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["U01DK100867"],"award-info":[{"award-number":["U01DK100867"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["U24DK100845"],"award-info":[{"award-number":["U24DK100845"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["U01DK100876 U01DK100866"],"award-info":[{"award-number":["U01DK100876 U01DK100866"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000005","name":"U.S. Department of Defense","doi-asserted-by":"publisher","award":["RC2-DK122397"],"award-info":[{"award-number":["RC2-DK122397"]}],"id":[{"id":"10.13039\/100000005","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000005","name":"U.S. Department of Defense","doi-asserted-by":"publisher","award":["W81XWH-16-1-0451"],"award-info":[{"award-number":["W81XWH-16-1-0451"]}],"id":[{"id":"10.13039\/100000005","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000005","name":"U.S. Department of Defense","doi-asserted-by":"publisher","award":["W81XWH-22-1-0966"],"award-info":[{"award-number":["W81XWH-22-1-0966"]}],"id":[{"id":"10.13039\/100000005","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["kidney-international.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.kint.2026.01.026","type":"journal-article","created":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T16:17:45Z","timestamp":1771949865000},"page":"1256-1268","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Polygenic risk scores and HLA class II variants are biomarkers of corticosteroid response in childhood nephrotic syndrome"],"prefix":"10.1016","volume":"109","author":[{"given":"Tiffany","family":"Tu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro","family":"Ochoa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amika","family":"Sood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley","family":"Dabrik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan","family":"Chryst-Stangl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brandon","family":"Lane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guanghong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Donovan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ursula","family":"Harper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Settara","family":"Chandrasekharappa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Esezobor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adaobi","family":"Solarin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Hooper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Sethna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Amaral","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoud","family":"Kallash","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2494-3970","authenticated-orcid":false,"given":"Michelle","family":"Rheault","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priya","family":"Verghese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8000-1385","authenticated-orcid":false,"given":"Vikas","family":"Dharnidharka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0974-3719","authenticated-orcid":false,"given":"Eloise","family":"Salmon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Weng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarak","family":"Srivastava","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael E.","family":"Seifert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cozumel","family":"Pruette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Selewski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keisha","family":"Gibson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tracy","family":"Hunley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asiri","family":"Abeyagunawardena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shenal","family":"Thalgahagoda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arvind","family":"Bagga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aditi","family":"Sinha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Webb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2490-021X","authenticated-orcid":false,"given":"Larry","family":"Greenbaum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Gharavi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krzysztof","family":"Kiryluk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4064-0582","authenticated-orcid":false,"given":"Matthias","family":"Kretzler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Guay-Woodford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"Sanna-Cherchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnieszka","family":"Bierzynska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ania","family":"Koziell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gavin","family":"Welsh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9808-4518","authenticated-orcid":false,"given":"Moin","family":"Saleem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Rotimi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eileen","family":"Chambers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cliburn","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annette","family":"Jackson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adebowale","family":"Adeyemo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5641-6644","authenticated-orcid":false,"given":"Rasheed","family":"Gbadegesin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.kint.2026.01.026_bib1","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/S0140-6736(23)01051-6","article-title":"Childhood nephrotic syndrome","volume":"402","author":"Vivarelli","year":"2023","journal-title":"Lancet"},{"key":"10.1016\/j.kint.2026.01.026_bib2","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1126\/science.1193032","article-title":"Association of trypanolytic ApoL1 variants with kidney disease in African Americans","volume":"329","author":"Genovese","year":"2010","journal-title":"Science"},{"key":"10.1016\/j.kint.2026.01.026_bib3","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1038\/s41572-020-0196-7","article-title":"Podocytopathies","volume":"6","author":"Kopp","year":"2020","journal-title":"Nat Rev Dis Primers"},{"key":"10.1016\/j.kint.2026.01.026_bib4","doi-asserted-by":"crossref","first-page":"1957","DOI":"10.1007\/s00467-021-05401-4","article-title":"An updated view of the pathogenesis of steroid-sensitive nephrotic syndrome","volume":"37","author":"Horinouchi","year":"2022","journal-title":"Pediatr Nephrol"},{"key":"10.1016\/j.kint.2026.01.026_bib5","doi-asserted-by":"crossref","first-page":"1701","DOI":"10.1681\/ASN.2014030247","article-title":"HLA-DQA1 and PLCG2 are candidate risk loci for childhood-onset steroid-sensitive nephrotic syndrome","volume":"26","author":"Gbadegesin","year":"2015","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.kint.2026.01.026_bib6","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1681\/ASN.2018101054","article-title":"Genetic identification of two novel loci associated with steroid-sensitive nephrotic syndrome","volume":"30","author":"Dufek","year":"2019","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.kint.2026.01.026_bib7","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1016\/j.kint.2020.05.029","article-title":"Common risk variants in NPHS1 and TNFSF15 are associated with childhood steroid-sensitive nephrotic syndrome","volume":"98","author":"Jia","year":"2020","journal-title":"Kidney Int"},{"key":"10.1016\/j.kint.2026.01.026_bib8","doi-asserted-by":"crossref","first-page":"2481","DOI":"10.1038\/s41467-023-37985-w","article-title":"Multi-population genome-wide association study implicates immune and non-immune factors in pediatric steroid-sensitive nephrotic syndrome","volume":"14","author":"Barry","year":"2023","journal-title":"Nat Commun"},{"key":"10.1016\/j.kint.2026.01.026_bib9","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/j.kint.2021.05.015","article-title":"Executive summary of the KDIGO 2021 Guideline for the Management of Glomerular Diseases","volume":"100","author":"Rovin","year":"2021","journal-title":"Kidney Int"},{"key":"10.1016\/j.kint.2026.01.026_bib10","doi-asserted-by":"crossref","first-page":"D941","DOI":"10.1093\/nar\/gkz836","article-title":"The International Genome Sample Resource (IGSR) collection of open human genomic variation resources","volume":"48","author":"Fairley","year":"2020","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.kint.2026.01.026_bib11","doi-asserted-by":"crossref","first-page":"1284","DOI":"10.1038\/ng.3656","article-title":"Next-generation genotype imputation service and methods","volume":"48","author":"Das","year":"2016","journal-title":"Nat Genet"},{"key":"10.1016\/j.kint.2026.01.026_bib12","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1038\/s41586-021-03205-y","article-title":"Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program","volume":"590","author":"Taliun","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.kint.2026.01.026_bib13","article-title":"Whole-genome sequencing of half-a-million UK Biobank participants. Preprint","author":"Li","year":"2023","journal-title":"medRxiv"},{"key":"10.1016\/j.kint.2026.01.026_bib14","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1053\/j.ajkd.2018.07.020","article-title":"CureGN study rationale, design, and methods: establishing a large prospective observational study of glomerular disease","volume":"73","author":"Mariani","year":"2019","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.kint.2026.01.026_bib15","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/s41586-023-06045-0","article-title":"A genomic mutational constraint map using variation in 76,156 human genomes","volume":"625","author":"Chen","year":"2024","journal-title":"Nature"},{"key":"10.1016\/j.kint.2026.01.026_bib16","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1038\/s41588-018-0184-y","article-title":"Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies","volume":"50","author":"Zhou","year":"2018","journal-title":"Nat Genet"},{"key":"10.1016\/j.kint.2026.01.026_bib17","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/j.ajhg.2015.09.001","article-title":"Modeling linkage disequilibrium increases accuracy of polygenic risk scores","volume":"97","author":"Vilhj\u00e1lmsson","year":"2015","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.kint.2026.01.026_bib18","doi-asserted-by":"crossref","first-page":"5424","DOI":"10.1093\/bioinformatics\/btaa1029","article-title":"LDpred2: better, faster, stronger","volume":"36","author":"Priv\u00e9","year":"2020","journal-title":"Bioinformatics"},{"key":"10.1016\/j.kint.2026.01.026_bib19","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1038\/s41588-021-00935-7","article-title":"A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response","volume":"53","author":"Luo","year":"2021","journal-title":"Nat Genet"},{"key":"10.1016\/j.kint.2026.01.026_bib20","doi-asserted-by":"crossref","first-page":"2625","DOI":"10.1038\/s41596-023-00853-4","article-title":"Tutorial: a statistical genetics guide to identifying HLA alleles driving complex disease","volume":"18","author":"Sakaue","year":"2023","journal-title":"Nat Protoc"},{"key":"10.1016\/j.kint.2026.01.026_bib21","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1053\/j.ajkd.2017.10.013","article-title":"HLA-DQA1 and APOL1 as risk loci for childhood-onset steroid-sensitive and steroid-resistant nephrotic syndrome","volume":"71","author":"Adeyemo","year":"2018","journal-title":"Am J Kidney Dis"},{"key":"10.1016\/j.kint.2026.01.026_bib22","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1007\/s00251-007-0224-8","article-title":"The spectrum of HLA-DQ and HLA-DR alleles, 2006: a listing correlating sequence and structure with function","volume":"59","author":"Bondinas","year":"2007","journal-title":"Immunogenetics"},{"key":"10.1016\/j.kint.2026.01.026_bib23","article-title":"Net benefit approaches to the evaluation of prediction models, molecular markers, and diagnostic tests","volume":"352","author":"Vickers","year":"2016","journal-title":"BMJ"},{"key":"10.1016\/j.kint.2026.01.026_bib24","doi-asserted-by":"crossref","DOI":"10.1111\/sji.13050","article-title":"Exploring the role of the multiple sclerosis susceptibility gene CLEC16A in T cells","volume":"94","author":"Eriksson","year":"2021","journal-title":"Scand J Immunol"},{"key":"10.1016\/j.kint.2026.01.026_bib25","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2021.618213","article-title":"Type 1 diabetes and autoimmune thyroid disease-the genetic link","volume":"12","author":"Frommer","year":"2021","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.1016\/j.kint.2026.01.026_bib26","doi-asserted-by":"crossref","first-page":"945","DOI":"10.4049\/jimmunol.1901409","article-title":"The role of autoimmunity-related gene CLEC16A in the B cell receptor-mediated HLA class II pathway","volume":"205","author":"Rijvers","year":"2020","journal-title":"J Immunol"},{"key":"10.1016\/j.kint.2026.01.026_bib27","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.msard.2019.01.033","article-title":"Genetic differences between primary progressive and relapsing-remitting multiple sclerosis: the impact of immune-related genes variability","volume":"29","author":"Kiselev","year":"2019","journal-title":"Mult Scler Relat Disord"},{"key":"10.1016\/j.kint.2026.01.026_bib28","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0132957","article-title":"Multiple sclerosis risk allele in CLEC16A acts as an expression quantitative trait locus for CLEC16A and SOCS1 in CD4+ T cells","volume":"10","author":"Leikfoss","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.kint.2026.01.026_bib29","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1016\/j.immuni.2015.04.011","article-title":"The autoimmunity-associated gene CLEC16A modulates thymic epithelial cell autophagy and alters T cell selection","volume":"42","author":"Schuster","year":"2015","journal-title":"Immunity"},{"key":"10.1016\/j.kint.2026.01.026_bib30","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1136\/ard.2009.114934","article-title":"A CLEC16A variant confers risk for juvenile idiopathic arthritis and anti-cyclic citrullinated peptide antibody negative rheumatoid arthritis","volume":"69","author":"Skinningsrud","year":"2010","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.kint.2026.01.026_bib31","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1038\/s10038-024-01272-3","article-title":"Genomic variants associated with age at diagnosis of childhood-onset type 1 diabetes","volume":"69","author":"Bougn\u00e8res","year":"2024","journal-title":"J Hum Genet"},{"key":"10.1016\/j.kint.2026.01.026_bib32","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1016\/j.diabet.2018.01.016","article-title":"No prognostic role of a GWAS-derived genetic risk score in renal outcomes for patients from French cohorts with type 1 and type 2 diabetes","volume":"45","author":"Barbieux","year":"2019","journal-title":"Diabetes Metab"},{"key":"10.1016\/j.kint.2026.01.026_bib33","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1038\/s41591-024-02796-z","article-title":"Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations","volume":"30","author":"Lennon","year":"2024","journal-title":"Nat Med"},{"key":"10.1016\/j.kint.2026.01.026_bib34","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1038\/s41588-023-01422-x","article-title":"Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy","volume":"55","author":"Kiryluk","year":"2023","journal-title":"Nat Genet"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253826001341?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253826001341?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T09:52:27Z","timestamp":1779270747000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253826001341"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":34,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["S0085253826001341"],"URL":"https:\/\/doi.org\/10.1016\/j.kint.2026.01.026","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Polygenic risk scores and HLA class II variants are biomarkers of corticosteroid response in childhood nephrotic syndrome","name":"articletitle","label":"Article Title"},{"value":"Kidney International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.kint.2026.01.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.kint.2026.04.003","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 International Society of Nephrology. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}