{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T21:28:57Z","timestamp":1787174937313,"version":"build-2736575974"},"reference-count":60,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2027,6,18]],"date-time":"2027-06-18T00:00:00Z","timestamp":1813276800000},"content-version":"am","delay-in-days":352,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01DK083345"],"award-info":[{"award-number":["R01DK083345"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["2020860\/Z\/16\/Z"],"award-info":[{"award-number":["2020860\/Z\/16\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research","doi-asserted-by":"publisher","award":["201503MOP-341962"],"award-info":[{"award-number":["201503MOP-341962"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004440","name":"Wellcome","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001804","name":"Canada Research Chairs Program","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001804","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100015150","name":"St Michael's Hospital Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100015150","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000062","name":"National Institute of Diabetes and Digestive and Kidney Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000062","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003579","name":"University of Toronto","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003579","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["kidney-international.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Kidney International"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.kint.2026.02.028","type":"journal-article","created":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T00:10:25Z","timestamp":1774311025000},"page":"145-160","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Reduced podocyte stiffness is a feature of proteinuric kidney disease"],"prefix":"10.1016","volume":"110","author":[{"given":"Luisa Ulloa","family":"Severino","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolin","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aditya","family":"Mandapati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianzhou","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sri Nagarjun","family":"Batchu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vatsal","family":"Sachan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian","family":"Kennedy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kendrix","family":"Kek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana","family":"Krizova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franziska","family":"Lausecker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Yip","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Advani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6400-0227","authenticated-orcid":false,"given":"Rachel","family":"Lennon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon E.","family":"Chase","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mira","family":"Krendel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0054-6607","authenticated-orcid":false,"given":"Darren A.","family":"Yuen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.kint.2026.02.028_bib1","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.lab.2005.08.011","article-title":"Reduced podocyte expression of alpha3beta1 integrins and podocyte depletion in patients with primary focal segmental glomerulosclerosis and chronic PAN-treated rats","volume":"147","author":"Chen","year":"2006","journal-title":"J Lab Clin Med"},{"key":"10.1016\/j.kint.2026.02.028_bib2","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.ydbio.2007.10.047","article-title":"Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus","volume":"313","author":"Kanasaki","year":"2008","journal-title":"Dev Biol"},{"key":"10.1016\/j.kint.2026.02.028_bib3","doi-asserted-by":"crossref","first-page":"3537","DOI":"10.1242\/dev.122.11.3537","article-title":"Alpha 3 beta 1 integrin has a crucial role in kidney and lung organogenesis","volume":"122","author":"Kreidberg","year":"1996","journal-title":"Development"},{"key":"10.1016\/j.kint.2026.02.028_bib4","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.ydbio.2008.01.022","article-title":"Beta1 integrin expression by podocytes is required to maintain glomerular structural integrity","volume":"316","author":"Pozzi","year":"2008","journal-title":"Dev Biol"},{"key":"10.1016\/j.kint.2026.02.028_bib5","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1038\/nrneph.2016.127","article-title":"Podocyte-actin dynamics in health and disease","volume":"12","author":"Perico","year":"2016","journal-title":"Nat Rev Nephrol"},{"key":"10.1016\/j.kint.2026.02.028_bib6","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1038\/nrneph.2011.151","article-title":"The podocyte cytoskeleton\u2013key to a functioning glomerulus in health and disease","volume":"8","author":"Welsh","year":"2011","journal-title":"Nat Rev Nephrol"},{"key":"10.1016\/j.kint.2026.02.028_bib7","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1681\/ASN.V123413","article-title":"Podocytes respond to mechanical stress in vitro","volume":"12","author":"Endlich","year":"2001","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.kint.2026.02.028_bib8","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.biomaterials.2018.07.033","article-title":"Activation of human aortic valve interstitial cells by local stiffness involves YAP-dependent transcriptional signaling","volume":"181","author":"Santoro","year":"2018","journal-title":"Biomaterials"},{"key":"10.1016\/j.kint.2026.02.028_bib9","doi-asserted-by":"crossref","first-page":"2553","DOI":"10.1016\/S0024-3205(03)00165-6","article-title":"Feeling the forces: atomic force microscopy in cell biology","volume":"72","author":"Alonso","year":"2003","journal-title":"Life Sci"},{"key":"10.1016\/j.kint.2026.02.028_bib10","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.146243","article-title":"Myofibroblast YAP\/TAZ activation is a key step in organ fibrogenesis","volume":"7","author":"He","year":"2022","journal-title":"JCI Insight"},{"key":"10.1016\/j.kint.2026.02.028_bib11","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.yexcr.2015.10.034","article-title":"Role of YAP\/TAZ in cell-matrix adhesion-mediated signalling and mechanotransduction","volume":"343","author":"Dupont","year":"2016","journal-title":"Exp Cell Res"},{"key":"10.1016\/j.kint.2026.02.028_bib12","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1038\/nature10137","article-title":"Role of YAP\/TAZ in mechanotransduction","volume":"474","author":"Dupont","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.kint.2026.02.028_bib13","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms15321","article-title":"YAP regulates cell mechanics by controlling focal adhesion assembly","volume":"8","author":"Nardone","year":"2017","journal-title":"Nat Commun"},{"key":"10.1016\/j.kint.2026.02.028_bib14","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1038\/s41419-018-0878-1","article-title":"Nuclear YAP localization as a key regulator of podocyte function","volume":"9","author":"Bonse","year":"2018","journal-title":"Cell Death Dis"},{"key":"10.1016\/j.kint.2026.02.028_bib15","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1681\/ASN.2014090916","article-title":"Podocyte-specific deletion of yes-associated protein causes FSGS and progressive renal failure","volume":"27","author":"Schwartzman","year":"2016","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.kint.2026.02.028_bib16","doi-asserted-by":"crossref","first-page":"F419","DOI":"10.1152\/ajprenal.00426.2021","article-title":"TAZ is important for maintenance of the integrity of podocytes","volume":"322","author":"Chen","year":"2022","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1016\/j.kint.2026.02.028_bib17","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1016\/j.kint.2024.01.038","article-title":"Inhibition of transcriptional coactivator YAP Impairs the expression and function of transcription factor WT1 in diabetic podocyte injury","volume":"105","author":"Chen","year":"2024","journal-title":"Kidney Int"},{"key":"10.1016\/j.kint.2026.02.028_bib18","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1681\/ASN.0000000000000107","article-title":"Activation of hippo pathway damages slit diaphragm by deprivation of ajuba proteins","volume":"34","author":"Gilhaus","year":"2023","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.kint.2026.02.028_bib19","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-019-49012-4","article-title":"A new, easily generated mouse model of diabetic kidney fibrosis","volume":"9","author":"He","year":"2019","journal-title":"Sci Rep"},{"key":"10.1016\/j.kint.2026.02.028_bib20","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.1097\/01.ASN.0000130562.90255.8F","article-title":"Mouse model of X-linked Alport syndrome","volume":"15","author":"Rheault","year":"2004","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.kint.2026.02.028_bib21","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1681\/ASN.2007111172","article-title":"Disruption of myosin 1e promotes podocyte injury","volume":"20","author":"Krendel","year":"2009","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.kint.2026.02.028_bib22","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.136995","article-title":"Photoacoustic imaging of kidney fibrosis for assessing pre-transplant organ quality","volume":"5","author":"Hysi","year":"2020","journal-title":"JCI Insight"},{"key":"10.1016\/j.kint.2026.02.028_bib23","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1097\/01.ASN.0000078803.53165.C9","article-title":"Expression of podocyte-associated molecules in acquired human kidney diseases","volume":"14","author":"Koop","year":"2003","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.kint.2026.02.028_bib24","doi-asserted-by":"crossref","first-page":"1602","DOI":"10.1007\/s10439-023-03168-3","article-title":"Pancreatic cancer presents distinct nanomechanical properties during progression","volume":"51","author":"Stylianou","year":"2023","journal-title":"Ann Biomed Eng"},{"issue":"54","key":"10.1016\/j.kint.2026.02.028_bib25","first-page":"2911","article-title":"Micro-mechanical characterization of lung tissue using atomic force microscopy","author":"Liu","year":"2011","journal-title":"J Vis Exp"},{"key":"10.1016\/j.kint.2026.02.028_bib26","doi-asserted-by":"crossref","first-page":"L344","DOI":"10.1152\/ajplung.00300.2014","article-title":"Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis","volume":"308","author":"Liu","year":"2015","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"10.1016\/j.kint.2026.02.028_bib27","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1083\/jcb.201004082","article-title":"Feedback amplification of fibrosis through matrix stiffening and COX-2 suppression","volume":"190","author":"Liu","year":"2010","journal-title":"J. Cell Biol"},{"key":"10.1016\/j.kint.2026.02.028_bib28","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1056\/NEJMoa1101273","article-title":"MYO1E mutations and childhood familial focal segmental glomerulosclerosis","volume":"365","author":"Mele","year":"2011","journal-title":"N Engl J Med"},{"key":"10.1016\/j.kint.2026.02.028_bib29","doi-asserted-by":"crossref","first-page":"F1099","DOI":"10.1152\/ajprenal.00251.2012","article-title":"Podocyte-specific knockout of myosin 1e disrupts glomerular filtration","volume":"303","author":"Chase","year":"2012","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1016\/j.kint.2026.02.028_bib30","doi-asserted-by":"crossref","first-page":"11972","DOI":"10.1073\/pnas.0901641106","article-title":"Control of cell membrane tension by myosin-I","volume":"106","author":"Nambiar","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.kint.2026.02.028_bib31","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1038\/s41467-019-09104-1","article-title":"Membrane-cytoskeletal crosstalk mediated by myosin-I regulates adhesion turnover during phagocytosis","volume":"10","author":"Barger","year":"2019","journal-title":"Nat Commun"},{"key":"10.1016\/j.kint.2026.02.028_bib32","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1126\/science.1116995","article-title":"Tissue cells feel and respond to the stiffness of their substrate","volume":"310","author":"Discher","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.kint.2026.02.028_bib33","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1038\/nrneph.2012.291","article-title":"Cell-matrix adhesion of podocytes in physiology and disease","volume":"9","author":"Sachs","year":"2013","journal-title":"Nat Rev Nephrol"},{"key":"10.1016\/j.kint.2026.02.028_bib34","doi-asserted-by":"crossref","first-page":"2061","DOI":"10.1038\/s41467-019-09936-x","article-title":"Disruption of podocyte cytoskeletal biomechanics by dasatinib leads to nephrotoxicity","volume":"10","author":"Calizo","year":"2019","journal-title":"Nat Commun"},{"key":"10.1016\/j.kint.2026.02.028_bib35","doi-asserted-by":"crossref","first-page":"160","DOI":"10.3389\/fendo.2014.00160","article-title":"The importance of podocyte adhesion for a healthy glomerulus","volume":"5","author":"Lennon","year":"2014","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.1016\/j.kint.2026.02.028_bib36","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1158\/1535-7163.MCT-20-0717","article-title":"Small molecule inhibitors of TEAD auto-palmitoylation selectively inhibit proliferation and tumor growth of NF2-deficient mesothelioma","volume":"20","author":"Tang","year":"2021","journal-title":"Mol Cancer Ther"},{"key":"10.1016\/j.kint.2026.02.028_bib37","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.adq3852","article-title":"Podocyte YAP and TAZ hyperactivation drives glomerular epithelial proliferative diseases in mice and humans","volume":"17","author":"He","year":"2025","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.kint.2026.02.028_bib38","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aaz4028","article-title":"NUAK1 promotes organ fibrosis via YAP and TGF-beta\/SMAD signaling","volume":"14","author":"Zhang","year":"2022","journal-title":"Sci Transl Med"},{"key":"10.1016\/j.kint.2026.02.028_bib39","doi-asserted-by":"crossref","first-page":"C397","DOI":"10.1152\/ajpcell.00438.2010","article-title":"Biophysical properties of normal and diseased renal glomeruli","volume":"300","author":"Wyss","year":"2011","journal-title":"Am J Physiol Cell Physiol"},{"key":"10.1016\/j.kint.2026.02.028_bib40","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1681\/ASN.2017050475","article-title":"Similar biophysical abnormalities in glomeruli and podocytes from two distinct models","volume":"29","author":"Embry","year":"2018","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.kint.2026.02.028_bib41","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0167924","article-title":"Biochemical and cellular determinants of renal glomerular elasticity","volume":"11","author":"Embry","year":"2016","journal-title":"PloS one"},{"key":"10.1016\/j.kint.2026.02.028_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2023.122389","article-title":"Atomic force microscopy-mediated mechanobiological profiling of complex human tissues","volume":"303","author":"Cho","year":"2023","journal-title":"Biomaterials"},{"key":"10.1016\/j.kint.2026.02.028_bib43","doi-asserted-by":"crossref","first-page":"12817","DOI":"10.1073\/pnas.1917555117","article-title":"Cell response to substrate rigidity is regulated by active and passive cytoskeletal stress","volume":"117","author":"Doss","year":"2020","journal-title":"Proc Natl Acad Sc U S A"},{"key":"10.1016\/j.kint.2026.02.028_bib44","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0092-8674(00)81856-5","article-title":"Extracellular matrix rigidity causes strengthening of integrin-cytoskeleton linkages","volume":"88","author":"Choquet","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.kint.2026.02.028_bib45","doi-asserted-by":"crossref","first-page":"3901","DOI":"10.1242\/jcs.03098","article-title":"Integrin ligands at a glance","volume":"119","author":"Humphries","year":"2006","journal-title":"J Cell Sci"},{"key":"10.1016\/j.kint.2026.02.028_bib46","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1056\/NEJMoa1110813","article-title":"Integrin alpha3 mutations with kidney, lung, and skin disease","volume":"366","author":"Has","year":"2012","journal-title":"N Engl J Med"},{"key":"10.1016\/j.kint.2026.02.028_bib47","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1159\/000507997","article-title":"Mechanisms of podocyte detachment, podocyturia, and risk of progression of glomerulopathies","volume":"6","author":"Trimarchi","year":"2020","journal-title":"Kidney Dis (Basel)"},{"key":"10.1016\/j.kint.2026.02.028_bib48","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1016\/j.kint.2016.01.012","article-title":"Podocyte injury and its consequences","volume":"89","author":"Nagata","year":"2016","journal-title":"Kidney Int"},{"key":"10.1016\/j.kint.2026.02.028_bib49","doi-asserted-by":"crossref","first-page":"302","DOI":"10.3389\/fendo.2018.00302","article-title":"Nephrin signaling in the podocyte: an updated view of signal regulation at the slit diaphragm and beyond","volume":"9","author":"Martin","year":"2018","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.1016\/j.kint.2026.02.028_bib50","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1038\/nrneph.2013.169","article-title":"The podocyte slit diaphragm\u2013from a thin grey line to a complex signalling hub","volume":"9","author":"Grahammer","year":"2013","journal-title":"Nature Rev Nephrol"},{"key":"10.1016\/j.kint.2026.02.028_bib51","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1172\/JCI27414","article-title":"Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization","volume":"116","author":"Verma","year":"2006","journal-title":"J Clin Invest"},{"key":"10.1016\/j.kint.2026.02.028_bib52","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1038\/nature04662","article-title":"Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes","volume":"440","author":"Jones","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.kint.2026.02.028_bib53","doi-asserted-by":"crossref","first-page":"12799","DOI":"10.1074\/jbc.M116.724245","article-title":"Nephrin suppresses hippo signaling through the adaptor proteins Nck and WTIP","volume":"291","author":"Keyvani Chahi","year":"2016","journal-title":"J Biol Chem"},{"key":"10.1016\/j.kint.2026.02.028_bib54","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms12502","article-title":"PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver fibrosis","volume":"7","author":"Martin","year":"2016","journal-title":"Nat Commun"},{"key":"10.1016\/j.kint.2026.02.028_bib55","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1101\/gad.253682.114","article-title":"A laminin 511 matrix is regulated by TAZ and functions as the ligand for the alpha6Bbeta1 integrin to sustain breast cancer stem cells","volume":"29","author":"Chang","year":"2015","journal-title":"Genes Dev"},{"key":"10.1016\/j.kint.2026.02.028_bib56","first-page":"1674","article-title":"Integrin signalling regulates YAP and TAZ to control skin homeostasis","volume":"143","author":"Elbediwy","year":"2016","journal-title":"Development"},{"key":"10.1016\/j.kint.2026.02.028_bib57","doi-asserted-by":"crossref","first-page":"19179","DOI":"10.1074\/jbc.M117.808063","article-title":"\u03b21 integrin-dependent Rac\/group I PAK signaling mediates YAP activation of Yes-associated protein 1 (YAP1) via NF2\/merlin","volume":"292","author":"Sabra","year":"2017","journal-title":"J Biol Chem"},{"key":"10.1016\/j.kint.2026.02.028_bib58","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1083\/jcb.201501025","article-title":"Adhesion to fibronectin regulates Hippo signaling via the FAK-Src-PI3K pathway","volume":"210","author":"Kim","year":"2015","journal-title":"J Cell Biol"},{"key":"10.1016\/j.kint.2026.02.028_bib59","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-020-72564-9","article-title":"Spatial mapping of the collagen distribution in human and mouse tissues by force volume atomic force microscopy","volume":"10","author":"Calo","year":"2020","journal-title":"Sci Rep"},{"key":"10.1016\/j.kint.2026.02.028_bib60","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.94137","article-title":"Injury-induced actin cytoskeleton reorganization in podocytes revealed by super-resolution microscopy","volume":"2","author":"Suleiman","year":"2017","journal-title":"JCI Insight"}],"container-title":["Kidney International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253826002255?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0085253826002255?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:55:39Z","timestamp":1787172939000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0085253826002255"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":60,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["S0085253826002255"],"URL":"https:\/\/doi.org\/10.1016\/j.kint.2026.02.028","relation":{},"ISSN":["0085-2538"],"issn-type":[{"value":"0085-2538","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Reduced podocyte stiffness is a feature of proteinuric kidney disease","name":"articletitle","label":"Article Title"},{"value":"Kidney International","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.kint.2026.02.028","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 International Society of Nephrology. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}