{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T19:07:22Z","timestamp":1786993642987,"version":"build-2736575974"},"reference-count":24,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2011,8,18]],"date-time":"2011-08-18T00:00:00Z","timestamp":1313625600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Kaohsiung J of Med Scie"],"published-print":{"date-parts":[[2011,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:label\/>\n                    <jats:p>\n                      In this prospective randomized clinical trial, we aimed to evaluate the safety and efficacy of endourethrotomy with holmium:yttrium\u2010aluminium\u2010garnet (HO:YAG) laser and compare the outcomes with the conventional cold\u2010knife urethrotomy. Fifty\u2010one male patients with single, iatrogenic, annular strictures of the urethra were randomly divided into two groups; 21 patients who underwent direct\u2010vision endoscopic urethrotomy with Ho:YAG laser (15 W; 1,200\u20131,400 mJ; 8\u201312 Hz) at 12 o'clock position (laser group) and 30 patients who underwent direct\u2010vision endoscopic urethrotomy with cold\u2010knife incision at 12 o'clock position (cold\u2010knife group). The results obtained were analyzed and compared at 3 months, 6 months, 9 months, and 12\u2009months postoperatively by clinical evaluation, uroflowmetry, and retrograde urethrographies. Variables were compared among groups using Fisher's exact and Mann Whitney U tests. There were no differences between two groups in terms of patient age, preoperative Qmax value, stricture location, and length. Operative time was shorter in laser group (16.4 \u00b1 8.04 minutes) when compared with cold\u2010knife group (23.8 \u00b1 5.47 minutes) (\n                      <jats:italic>p<\/jats:italic>\n                      &lt; 0.001). Recurrence\u2010free rate at 3\u2009months was similar between two groups (\n                      <jats:italic>p<\/jats:italic>\n                      = 0.122). However, recurrence\u2010free rates at 6\u2009months, 9 months, and 12 months were significantly higher in laser group when compared with cold\u2010knife group (\n                      <jats:italic>p<\/jats:italic>\n                      values were 0.045, 0.027, and 0.04, respectively). No intra\u2010 or postoperative complications were encountered. Use of Ho:YAG laser in the management of urethral stricture disease is a safe and effective method. In addition, it provides shorter operative time and lower recurrence rate when compared with the conventional technique.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.kjms.2011.06.013","type":"journal-article","created":{"date-parts":[[2011,8,18]],"date-time":"2011-08-18T22:39:32Z","timestamp":1313707172000},"page":"503-507","source":"Crossref","is-referenced-by-count":27,"title":["Low\u2010power holmium:YAG laser urethrotomy for urethral stricture disease: Comparison of\u2009outcomes with the cold\u2010knife 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