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The purpose of this study was to determine the influence of the two commonly used intravenous anesthetics (propofol and thiamylal) on EMG amplitude evoked from the recurrent laryngeal nerve (RLN) during thyroid surgery. A total of 40 patients were randomized to receive a bolus of propofol (0.5\u2009mg\/kg; <jats:italic>n<\/jats:italic>\u2009=\u200920) or thiamylal (1.5\u2009mg\/kg; <jats:italic>n<\/jats:italic>\u2009=\u200920) to increase anesthetic depth when the surgeon found patient movement intraoperatively. Evoked potentials were obtained before and every 1\u2009minute after the administration of each agent for up to 5\u2009minutes by stimulating the RLN. The magnitude of evoked potentials at each time point and hemodynamic response were compared within groups. The mean amplitude of evoked potentials did not change significantly after administration of either propofol or thiamylal (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05 within groups). Mean arterial pressure measured from 1\u2009minute to 5\u2009minutes was significantly lower in the propofol group than in the thiamylal group (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). Heart rate measured within 5\u2009minutes did not differ significantly within groups. Low dose of propofol (0.5\u2009mg\/kg) or thiamylal (1.5\u2009mg\/kg) did not affect EMG readings during neuromonitoring of the RLN in thyroid surgery. Our results show that thiamylal provides better hemodynamic stability than propofol, and is therefore a preferable agent to increase anesthesia depth and prevent further patient movement during intraoperative neuromonitoring.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.kjms.2014.05.009","type":"journal-article","created":{"date-parts":[[2014,7,4]],"date-time":"2014-07-04T02:15:12Z","timestamp":1404440112000},"page":"499-503","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Influence of intravenous anesthetics on neuromonitoring of the recurrent laryngeal nerve during thyroid 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