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This prospective observational cross\u2010sectional study enrolled 22 eyes of 22 newly\u2010diagnosed patients with PXG in a single center. All of the patients received a fixed combination of dorzolamide\/timolol. Besides routine ophthalmologic examination, the retrobulbar hemodynamic parameters in the ophthalmic artery, central retinal artery, and short posterior ciliary arteries were measured in all participants at baseline and the 3<jats:sup>rd<\/jats:sup> month using color Doppler imaging. The mean intraocular pressure (IOP) was 22.3\u2009\u00b1\u20092.1\u2009mmHg at baseline and reduced to 17.4\u2009\u00b1\u20092.3\u2009mmHg at the 3<jats:sup>rd<\/jats:sup> month (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). None of the retrobulbar parameters, except peak systolic velocity and resistive index in temporal short posterior ciliary arteries, changed significantly on therapy with dorzolamide\/timolol fixed combination when the results were analyzed at Month 3. The drug significantly decreased the peak systolic velocity (<jats:italic>p<\/jats:italic>\u2009=\u20090.044) and reduced the resistive index in 0.04 units, 95% confidence interval 0.03\u20130.05, (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) in the temporal short posterior ciliary arteries. This study reports that the retrobulbar hemodynamics might be affected less than expected by dorzolamide\/timolol fixed combination in patients with PXG although the reduction of IOP was statistically significant.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.kjms.2015.12.004","type":"journal-article","created":{"date-parts":[[2016,1,23]],"date-time":"2016-01-23T05:46:22Z","timestamp":1453527982000},"page":"38-43","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Effects of dorzolamide\/timolol fixed combination on retrobulbar hemodynamics in pseudoexfoliative glaucoma"],"prefix":"10.1002","volume":"32","author":[{"given":"Mustafa","family":"Eliacik","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sevil","family":"Karaman Erdur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inci","family":"Baltepe 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