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A total of 99 patients with non\u2010obstructive azoospermia were divided into subgroups [19 patientsin hypospermatogenesis group (S1), 40 patients in maturation arrest group (S2), 20 patients in a Sertoli cell\u2010only syndrome (S3), and 20 patients in a testicular atrophy and fibrosis group (S4)], and 20 patients with obstructive azoospermia group (S0). Sections stained with a c\u2010kit antibody were studied by light microscopy to determine the number and distribution of Cajal\u2010like cells in peritubular and perivascular areas of testis. The number of Cajal\u2010like cells were higher in all the non\u2010obstructive groups than in the obstructive group (S0: 2.43 cells\/mm<jats:sup>2<\/jats:sup>, S1: 3.14 cells\/mm<jats:sup>2<\/jats:sup>, S2: 4.00 cells\/mm<jats:sup>2<\/jats:sup>, S3: 4.57 cells\/mm<jats:sup>2<\/jats:sup>, S4: 3.86 cells\/mm<jats:sup>2<\/jats:sup>) but statistically significantly different (<jats:italic>p<\/jats:italic> &lt; 0.05) in the S2 and S3 subgroups only. Distribution of Cajal\u2010like cells were similar in all groups. The number and distribution of Cajal\u2010like cells in non\u2010obstructive groups suggest that these cells may affect spermatogenesis. This cellular type can be responsible for the regulation of cellular motility or spermatogenesis. Electrophysiological and electron microscopic studies are needed to better define morphology and function of Cajal\u2010like cells in the testis, especially totally the normal testis tissue.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.kjms.2017.01.006","type":"journal-article","created":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T03:16:30Z","timestamp":1488338190000},"page":"181-186","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["Distribution and number of Cajal\u2010like cells in testis tissue with azoospermia"],"prefix":"10.1002","volume":"33","author":[{"given":"Eray","family":"Hasirci","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tahsin","family":"Turunc","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nebil","family":"Bal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehmet Resit","family":"Goren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huseyin","family":"Celik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enis","family":"Kervancioglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayhan","family":"Dirim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa 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