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The materials for this study were 32 Wistar albino female rats. The study groups were formed as follows: the cystitis group (Group 1), the cystitis\u2009+\u2009HCG protection group (Group 2), the cystitis\u2009+\u2009HCG treatment group (Group 3), and the control group (Group 4), with eight rats in each group. In this study, blood and urine samples were taken from the rats, they were euthanized, and their bladders were removed for glutathione, malondialdehyde, tumor necrosis factor alpha, and interferon gamma measurements. It was observed that tissue damage in Group 2 was lower than that in the other two groups. Glutathione levels in Groups 2 and 4 were significantly higher than in Groups 1 and 3 (<jats:italic>p<\/jats:italic>\u2009=\u20090.01). Malondialdehyde levels of Groups 2 and 4 were significantly lower than the values in Groups 1 and 3 (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). When the cystitis groups were compared in terms of their interferon gamma and tumor necrosis factor alpha levels, the lowest interferon gamma and tumor necrosis factor alpha levels were detected in Group 3. It was found that HCG has positive effects on experimental cystitis in rats. This study revealed that HCG should be researched as a therapeutic agent and formed a step for studies to be carried out on this subject.<\/jats:p><\/jats:sec>","DOI":"10.1016\/j.kjms.2017.02.003","type":"journal-article","created":{"date-parts":[[2017,3,27]],"date-time":"2017-03-27T19:40:15Z","timestamp":1490643615000},"page":"229-235","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Assessment of therapeutic effect of human choriogonadotropin in a chemical cystitis model"],"prefix":"10.1002","volume":"33","author":[{"given":"Serhat","family":"Tanik","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K\u00fcrsad","family":"Zengin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebahattin","family":"Albayrak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdullah","family":"Gurel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhittin","family":"Atar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sevinc","family":"Sahin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nevin","family":"Tuzcu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet","family":"Tuzcu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammet Abdurrahim","family":"Imamoglu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mesut","family":"Gurdal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,3,27]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2490-12-17"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tjog.2012.10.002"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-2042.2008.02208.x"},{"issue":"3","key":"e_1_2_7_5_2","doi-asserted-by":"crossref","first-page":"S54","DOI":"10.3949\/ccjm.74.Suppl_3.S54","article-title":"Interstitial cystitis\/painful bladder syndrome: symptom recognition is key to early identification, treatment","volume":"74","author":"Rosenberg M.T.","year":"2007","journal-title":"Cleve Clin J Med"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/1756287211398255"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11934-006-0051-8"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2006.08.016"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.7314\/APJCP.2014.15.18.7781"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1096\/fj.06-5885fje"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1021207014429"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.167.8.814"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2002-020642"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-011-0755-3"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(99)01936-8"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.4103\/0366-6999.154316"},{"key":"e_1_2_7_17_2","doi-asserted-by":"crossref","first-page":"319","DOI":"10.5505\/tjtes.2014.39586","article-title":"The effects of sildenafil in liver and kidney injury in a rat model of severe scald burn: a biochemical and histopathological study","volume":"20","author":"Gokakin A.K.","year":"2014","journal-title":"Ulus Travma Acil Cerrahi Derg"},{"key":"e_1_2_7_18_2","first-page":"882","article-title":"Improved method for the determination of blood glutathione","volume":"61","author":"Beutler E.","year":"1963","journal-title":"J Lab Clin Med"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(79)90708-7"},{"key":"e_1_2_7_20_2","doi-asserted-by":"publisher","DOI":"10.4103\/0253-7613.108283"},{"key":"e_1_2_7_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/cbf.1347"},{"key":"e_1_2_7_22_2","first-page":"76","article-title":"Chronic ulcerating interstitial cystitis (Hunner's ulcer). 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