{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T21:53:53Z","timestamp":1789422833925,"version":"build-2803163510"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T00:00:00Z","timestamp":1512518400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T00:00:00Z","timestamp":1512518400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T00:00:00Z","timestamp":1512518400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,3,13]],"date-time":"2017-03-13T00:00:00Z","timestamp":1489363200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["kjms-online.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Kaohsiung J of Med Scie"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:label\/>\n                    <jats:p>\n                      The aim of this study is to compare optical coherence tomography (OCT) findings of retinal thickness (RT) and retinal nerve fiber layer thickness (RNFLT) of idiopathic Parkinson's disease (IPD) patients to those of healthy subjects, and to investigate whether there is any relationship between the severity of the disease and the RNFLT values. This prospective study was included 25 IPD patients and 29 healthy controls. In the IPD group, the Hoehn and Yahr (H&amp;Y),\n                      <jats:italic>Unified Parkinson's Disease Rating Scale<\/jats:italic>\n                      (UPDRS), and Mini\u2010Mental State Exam (MMSE) were performed. Intraocular pressure (IOP), visual acuity (VA), spherical equivalent, axial length (AL), and central corneal thickness (CCT) were measured using OCT in both groups. The RT was measured in the central retinal (RTc), nasal (RTn), and temporal (RTt) segments. Nasal (RNFLTn), nasal superior (RNFLTns), nasal inferior (RNFLTni), temporal (RNFLTt), temporal superior (RNFLTts), and temporal inferior (RNFLTti) measurements were made and mean RTFLT was calculated (RNFLTg) for each individual. In the patient group, IOP and VA values were statistically significantly lower The RTn and RNFLTg were significantly thinner in the patient group. There was no statistically significant relationship between the severity of IPD and these findings. In our study, RNFLTg and RTn were found to be thinner in the IPD group, which may have caused lower VA scores. The effects of retinal dopamine depletion on RT and RNFLT, and lower IOP values in the non\u2010glaucomatous IPD patients should be further investigated.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.kjms.2017.11.006","type":"journal-article","created":{"date-parts":[[2017,12,6]],"date-time":"2017-12-06T04:26:16Z","timestamp":1512534376000},"page":"166-171","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":35,"title":["Optical coherence tomography findings in Parkinson's disease"],"prefix":"10.1002","volume":"34","author":[{"given":"Turkoglu Sule","family":"Aydin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dogan","family":"Umit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ogun Muhammed","family":"Nur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulas","family":"Fatih","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keles","family":"Asena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ozturk Yavas","family":"Nefise","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yildiz","family":"Serpil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,12,6]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.59.3.408"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(11)70097-7"},{"key":"e_1_2_6_4_2","first-page":"2473","article-title":"Decreased dopamine in the retinas of patients with Parkinson's disease","volume":"31","author":"Harnois C.","year":"1990","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"e_1_2_6_5_2","first-page":"433","article-title":"Potential role of retina as a biomarker for progression of Parkinson's disease","volume":"4","author":"Tian T.","year":"2011","journal-title":"Int J Ophthalmol"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25741"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25747"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.13-13062"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10633-007-9091-8"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.visres.2004.06.009"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.5301\/EJO.2010.1318"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-012-1125-7"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2013.4"},{"key":"e_1_2_6_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/WNO.0b013e3182701745"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2012.03701.x"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2011.03.004"},{"key":"e_1_2_6_17_2","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S15136"},{"key":"e_1_2_6_18_2","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0034891","article-title":"Optical coherence tomography in Parkinsonian syndromes","volume":"7","author":"Albrecht P.","year":"2012","journal-title":"PLoS One"},{"key":"e_1_2_6_19_2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2415-12-54","article-title":"Perimetric and retinal nerve fiber layer findings in patients with Parkinson's disease","volume":"12","author":"Tsironi E.E.","year":"2012","journal-title":"BMC Ophthalmol"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25896"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1177\/1352458510397414"},{"key":"e_1_2_6_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2012.01.046"},{"key":"e_1_2_6_23_2","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2008.137471"},{"key":"e_1_2_6_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2011.02.014"},{"key":"e_1_2_6_25_2","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-121975"},{"key":"e_1_2_6_26_2","doi-asserted-by":"publisher","DOI":"10.1586\/ern.12.49"},{"key":"e_1_2_6_27_2","article-title":"Retinal nerve fiber layer thickness changes in Parkinson disease: a meta\u2010analysis","volume":"9","author":"Yu J.G.","year":"2014","journal-title":"PLoS One"},{"key":"e_1_2_6_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2015.08.002"},{"key":"e_1_2_6_29_2","doi-asserted-by":"publisher","DOI":"10.1212\/01.WNL.0000103444.45882.D8"},{"key":"e_1_2_6_30_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1444-0938.2007.00211.x"},{"key":"e_1_2_6_31_2","doi-asserted-by":"publisher","DOI":"10.3233\/JPD-150686"}],"container-title":["The Kaohsiung Journal of Medical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1607551X17301158?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1607551X17301158?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.kjms.2017.11.006","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1016\/j.kjms.2017.11.006","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1016\/j.kjms.2017.11.006","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T11:43:55Z","timestamp":1772970235000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1016\/j.kjms.2017.11.006"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,6]]},"references-count":30,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["10.1016\/j.kjms.2017.11.006"],"URL":"https:\/\/doi.org\/10.1016\/j.kjms.2017.11.006","archive":["Portico"],"relation":{},"ISSN":["1607-551X","2410-8650"],"issn-type":[{"value":"1607-551X","type":"print"},{"value":"2410-8650","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,12,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Optical coherence tomography findings in Parkinson's disease","name":"articletitle","label":"Article Title"},{"value":"The Kaohsiung Journal of Medical Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.kjms.2017.11.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Kaohsiung Medical University. Published by Elsevier Taiwan LLC.","name":"copyright","label":"Copyright"}]}}