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Viruses, particularly enteroviruses, are major environmental candidates in the pathogenesis of type 1 diabetes, even though the mechanisms of pathogenicity of these viruses and their effects on the immune system have not been understood very well yet. Previous studies show that any imbalance in the population of different lymphocyte subsets could develop autoimmune diseases. Our theory is that enteroviral infection causes an impairment in the distribution of lymphocyte subtypes and consequently results in the diabetes onset in some individuals. Therefore, in this project, we evaluated the distribution of T CD8+ lymphocytes and their subsets in type 1 diabetes patients. This study was conducted to investigate the relationship between enteroviral infection and type 1 diabetes mellitus in an Iranian population, and suggestion a predicting approach for susceptible subjects.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.kjms.2017.12.010","type":"journal-article","created":{"date-parts":[[2018,1,20]],"date-time":"2018-01-20T07:55:36Z","timestamp":1516434936000},"page":"274-280","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Alteration in CD8\n                    <sup>+<\/sup>\n                    T cell subsets in enterovirus\u2010infected patients: An alarming factor for type 1 diabetes mellitus"],"prefix":"10.1002","volume":"34","author":[{"given":"Omid","family":"Zargari 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