{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T16:21:23Z","timestamp":1793118083180,"version":"4.5.0"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T00:00:00Z","timestamp":1716508800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100002015","name":"Chicago Baseball Cancer Charities","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100002015","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","thekneejournal.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Knee"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1016\/j.knee.2024.05.006","type":"journal-article","created":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T21:48:18Z","timestamp":1718228898000},"page":"70-78","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Outcomes following gel-based autologous chondrocyte implantation for articular cartilage defects of the knee"],"prefix":"10.1016","volume":"49","author":[{"given":"Dinshaw N.","family":"Pardiwala","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sachin","family":"Tapasvi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepak","family":"Chaudhary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashish","family":"Babhulkar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob","family":"Varghese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Rajan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhay","family":"Narvekar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parag","family":"Sancheti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.knee.2024.05.006_b0005","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.ijsu.2019.06.007","article-title":"Is implantation of autologous chondrocytes superior to microfracture for articular-cartilage defects of the knee? A systematic review of 5-year follow-up data","volume":"68","author":"Na","year":"2019","journal-title":"Int J Surg"},{"issue":"3","key":"10.1016\/j.knee.2024.05.006_b0010","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1177\/1947603518756463","article-title":"Long-term clinical and MRI results of matrix-assisted autologous chondrocyte implantation for articular cartilage defects of the knee","volume":"10","author":"Kreuz","year":"2019","journal-title":"Cartilage"},{"issue":"4","key":"10.1016\/j.knee.2024.05.006_b0015","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1007\/s00167-020-06148-5","article-title":"Third generation autologous chondrocyte implantation is a good treatment option for athletic persons","volume":"29","author":"Niethammer","year":"2021","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"issue":"2","key":"10.1016\/j.knee.2024.05.006_b0020","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1177\/1941738115611350","article-title":"Knee articular cartilage repair and restoration techniques: a review of the literature","volume":"8","author":"Richter","year":"2016","journal-title":"Sports Health"},{"key":"10.1016\/j.knee.2024.05.006_b0025","doi-asserted-by":"crossref","first-page":"1085S","DOI":"10.1177\/1947603520921433","article-title":"Biomechanical changes of repair tissue after autologous chondrocyte implantation at long-term follow-up","volume":"13","author":"Paatela","year":"2021","journal-title":"Cartilage"},{"key":"10.1016\/j.knee.2024.05.006_b0030","series-title":"Knee arthroscopy","article-title":"Cartilage repair with autogenous cells","author":"Ra","year":"2021"},{"issue":"6","key":"10.1016\/j.knee.2024.05.006_b0035","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1177\/0363546509346395","article-title":"Cell carriers as the next generation of cell therapy for cartilage repair: a review of the matrix-induced autologous chondrocyte implantation procedure","volume":"38","author":"Brittberg","year":"2010","journal-title":"Am J Sports Med"},{"key":"10.1016\/j.knee.2024.05.006_b0040","doi-asserted-by":"crossref","first-page":"7912975","DOI":"10.1155\/2018\/7912975","article-title":"Sustained results in long-term follow-up of autologous chondrocyte implantation (ACI) for distal femur juvenile osteochondritis Dissecans (JOCD)","volume":"2018","author":"Beck","year":"2018","journal-title":"Adv Orthop"},{"issue":"4","key":"10.1016\/j.knee.2024.05.006_b0045","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1177\/1947603516630786","article-title":"Long-term outcomes after autologous chondrocyte implantation: A systematic review at mean follow-up of 11.4 years","volume":"7","author":"Pareek","year":"2016","journal-title":"Cartilage"},{"issue":"1","key":"10.1016\/j.knee.2024.05.006_b0050","doi-asserted-by":"crossref","first-page":"159","DOI":"10.25259\/JASSM_11_2020","article-title":"Recent advances and future trends in articular cartilage repair","volume":"1","author":"Goyal","year":"2020","journal-title":"J Arthrosc Surg Sport Med"},{"issue":"2","key":"10.1016\/j.knee.2024.05.006_b0055","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.knee.2015.08.015","article-title":"Gel-type autologous chondrocyte implantation for cartilage repair in patients with prior ACL reconstruction: a retrospective two year follow-up","volume":"23","author":"van Duijvenbode","year":"2016","journal-title":"Knee"},{"issue":"6","key":"10.1016\/j.knee.2024.05.006_b0060","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1007\/s00167-012-2096-1","article-title":"The use of fibrin matrix-mixed gel-type autologous chondrocyte implantation in the treatment for osteochondral lesions of the talus","volume":"21","author":"Lee","year":"2013","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"10.1016\/j.knee.2024.05.006_b0065","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1186\/1471-2474-11-103","article-title":"Gel-type autologous chondrocyte (Chondron) implantation for treatment of articular cartilage defects of the knee","volume":"11","author":"Choi","year":"2010","journal-title":"BMC Musculoskelet Disord"},{"issue":"1","key":"10.1016\/j.knee.2024.05.006_b0070","first-page":"27","article-title":"Gel based autologous chondrocyte implantation: the surgical technique","volume":"4","author":"Goyal","year":"2019","journal-title":"Asian J Arthrosc"},{"issue":"4","key":"10.1016\/j.knee.2024.05.006_b0075","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1007\/s00167-009-0905-y","article-title":"Autologous chondrocyte implantation in the knee using fibrin","volume":"18","author":"Kim","year":"2010","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"issue":"11","key":"10.1016\/j.knee.2024.05.006_b0080","doi-asserted-by":"crossref","first-page":"2263","DOI":"10.1007\/s00167-012-1891-z","article-title":"Treatment of severe osteochondral defects of the knee by combined autologous bone grafting and autologous chondrocyte implantation using fibrin gel","volume":"20","author":"K\u00f6nst","year":"2012","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"key":"10.1016\/j.knee.2024.05.006_b0085","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/685690","article-title":"Fibrin gel as an injectable biodegradable scaffold and cell carrier for tissue engineering","volume":"2015","author":"Li","year":"2015","journal-title":"Sci World J"},{"issue":"11\u201312","key":"10.1016\/j.knee.2024.05.006_b0090","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1089\/ten.tea.2011.0272","article-title":"Fibrin-based model for cartilage regeneration: tissue maturation from in vitro to in vivo","volume":"18","author":"Deponti","year":"2012","journal-title":"Tissue Eng Part A"},{"issue":"12","key":"10.1016\/j.knee.2024.05.006_b0095","first-page":"883","article-title":"Gel-based autologous chondrocyte implantation (GACI) in the knee: multicentric short term study","volume":"9","author":"Dalal","year":"2016","journal-title":"Int J Health Sci"},{"issue":"10","key":"10.1016\/j.knee.2024.05.006_b0100","article-title":"Autologous chondrocyte implantation for full thickness articular cartilage defects of the knee","volume":"2010","author":"Vasiliadis","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"issue":"3","key":"10.1016\/j.knee.2024.05.006_b0105","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/j.knee.2016.02.001","article-title":"Autologous chondrocyte implantation (ACI) for cartilage defects of the knee: a guideline by the working group \u201cClinical Tissue Regeneration\u201d of the German Society of Orthopaedics and Trauma (DGOU)","volume":"23","author":"Niemeyer","year":"2016","journal-title":"Knee"},{"issue":"2","key":"10.1016\/j.knee.2024.05.006_b0110","doi-asserted-by":"crossref","first-page":"e5","DOI":"10.2106\/JBJS.RVW.17.00078","article-title":"Autologous chondrocyte implantation (ACI) for knee cartilage defects: a review of indications, technique, and outcomes","volume":"6","author":"Krill","year":"2018","journal-title":"JBJS Rev"},{"issue":"1","key":"10.1016\/j.knee.2024.05.006_b0115","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.ejrad.2005.08.009","article-title":"Cartilage repair: generations of autologous chondrocyte transplantation","volume":"57","author":"Marlovits","year":"2006","journal-title":"Eur J Radiol"},{"issue":"11","key":"10.1016\/j.knee.2024.05.006_b0120","doi-asserted-by":"crossref","first-page":"2091","DOI":"10.1177\/0363546508322131","article-title":"Characteristic complications after autologous chondrocyte implantation for cartilage defects of the knee joint","volume":"36","author":"Niemeyer","year":"2008","journal-title":"Am J Sports Med"},{"issue":"2","key":"10.1016\/j.knee.2024.05.006_b0125","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.arthro.2008.10.009","article-title":"New technique for cell-seeded collagen-matrix-supported autologous chondrocyte transplantation","volume":"25","author":"Steinwachs","year":"2009","journal-title":"Arthroscopy"},{"issue":"6","key":"10.1016\/j.knee.2024.05.006_b0130","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1007\/s00264-022-05369-2","article-title":"Efficacy and safety of CARTIGROW\u00ae in patients with articular cartilage defects of the knee joint: a four year prospective studys","volume":"46","author":"Pathak","year":"2022","journal-title":"Int Orthop"},{"issue":"2","key":"10.1016\/j.knee.2024.05.006_b0135","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1177\/230949900601400202","article-title":"Effectiveness of autologous fibrin tissue adhesive in reducing postoperative blood loss during total hip arthroplasty: a prospective randomised study of 100 cases","volume":"14","author":"Mawatari","year":"2006","journal-title":"J Orthop Surg (Hong Kong)"},{"issue":"2","key":"10.1016\/j.knee.2024.05.006_b0140","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1177\/0363546507311095","article-title":"Characterized chondrocyte implantation results in better structural repair when treating symptomatic cartilage defects of the knee in a randomized controlled trial versus microfracture","volume":"36","author":"Saris","year":"2008","journal-title":"Am J Sports Med"},{"key":"10.1016\/j.knee.2024.05.006_b0145","doi-asserted-by":"crossref","first-page":"10S","DOI":"10.1177\/0363546509350694","article-title":"Treatment of symptomatic cartilage defects of the knee: characterized chondrocyte implantation results in better clinical outcome at 36 months in a randomized trial compared to microfracture","volume":"37","author":"Saris","year":"2009","journal-title":"Am J Sports Med"},{"issue":"10","key":"10.1016\/j.knee.2024.05.006_b0150","doi-asserted-by":"crossref","first-page":"3186","DOI":"10.1007\/s00167-016-4262-3","article-title":"Return to sport after the surgical management of articular cartilage lesions in the knee: a meta-analysis","volume":"25","author":"Krych","year":"2017","journal-title":"Knee Surg Sports Traumatol Arthrosc"},{"issue":"374","key":"10.1016\/j.knee.2024.05.006_b0155","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1097\/00003086-200005000-00020","article-title":"Two- to 9-year outcome after autologous chondrocyte transplantation of the knee","volume":"374","author":"Peterson","year":"2000","journal-title":"Clin Orthop Relat Res"},{"issue":"1","key":"10.1016\/j.knee.2024.05.006_b0160","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1177\/0363546513506593","article-title":"Long-term outcomes after first-generation autologous chondrocyte implantation for cartilage defects of the knee","volume":"42","author":"Niemeyer","year":"2014","journal-title":"Am J Sports Med"},{"issue":"1_suppl","key":"10.1016\/j.knee.2024.05.006_b0165","doi-asserted-by":"crossref","first-page":"829S","DOI":"10.1177\/1947603519888001","article-title":"Return to work after autologous chondrocyte implantation of the knee in patients with workers compensation insurance","volume":"13","author":"Lane","year":"2021","journal-title":"Cartilage"}],"container-title":["The Knee"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968016024000747?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0968016024000747?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,8,23]],"date-time":"2024-08-23T22:31:17Z","timestamp":1724452277000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0968016024000747"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":33,"alternative-id":["S0968016024000747"],"URL":"https:\/\/doi.org\/10.1016\/j.knee.2024.05.006","relation":{},"ISSN":["0968-0160"],"issn-type":[{"value":"0968-0160","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Outcomes following gel-based autologous chondrocyte implantation for articular cartilage defects of the knee","name":"articletitle","label":"Article Title"},{"value":"The Knee","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.knee.2024.05.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}