{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T00:32:14Z","timestamp":1789000334860,"version":"build-2803163510"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T00:00:00Z","timestamp":1714521600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,3,26]],"date-time":"2024-03-26T00:00:00Z","timestamp":1711411200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["thelancet.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Lancet Regional Health - Americas"],"published-print":{"date-parts":[[2024,5]]},"DOI":"10.1016\/j.lana.2024.100733","type":"journal-article","created":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T03:54:03Z","timestamp":1713326043000},"page":"100733","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Post-COVID-19 respiratory sequelae two years after hospitalization: an ambidirectional study"],"prefix":"10.1016","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1618-8509","authenticated-orcid":false,"given":"Carlos Roberto","family":"Ribeiro Carvalho","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Celina de Almeida","family":"Lamas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis Augusto","family":"Visani de Luna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo Caruso","family":"Chate","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o Marcos","family":"Salge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcio Valente","family":"Yamada Sawamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Toufen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle Louvaes","family":"Garcia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula Gobi","family":"Scudeller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cesar Higa","family":"Nomura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0964-6222","authenticated-orcid":false,"given":"Marco Antonio","family":"Gutierrez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno Guedes","family":"Baldi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.lana.2024.100733_bib1","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.ejim.2021.06.009","article-title":"Prevalence of post-COVID-19 symptoms in hospitalized and non-hospitalized COVID-19 survivors: a systematic review and meta-analysis","volume":"92","author":"Fern\u00e1ndez-de-Las-Pe\u00f1as","year":"2021","journal-title":"Eur J Intern Med"},{"key":"10.1016\/j.lana.2024.100733_bib2","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1038\/s41591-021-01283-z","article-title":"Post-acute COVID-19 syndrome","volume":"27","author":"Nalbandian","year":"2021","journal-title":"Nat Med"},{"key":"10.1016\/j.lana.2024.100733_bib3","doi-asserted-by":"crossref","first-page":"e074425","DOI":"10.1136\/bmj-2022-074425","article-title":"Recovery and symptom trajectories up to two years after SARS-CoV-2 infection: population based, longitudinal cohort study","volume":"381","author":"Ballouz","year":"2023","journal-title":"BMJ"},{"key":"10.1016\/j.lana.2024.100733_bib4","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/S2213-2600(23)00239-4","article-title":"Post-acute sequelae of COVID-19: understanding and addressing the burden of multisystem manifestations","volume":"11","author":"Parotto","year":"2023","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.lana.2024.100733_bib5","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1186\/s12931-020-01429-6","article-title":"Impact of coronavirus disease 2019 on pulmonary function in early convalescence phase","volume":"21","author":"Huang","year":"2020","journal-title":"Respir Res"},{"key":"10.1016\/j.lana.2024.100733_bib6","doi-asserted-by":"crossref","first-page":"e222888","DOI":"10.1148\/radiol.222888","article-title":"Longitudinal assessment of chest CT findings and pulmonary function after COVID-19 infection","volume":"307","author":"Han","year":"2023","journal-title":"Radiology"},{"key":"10.1016\/j.lana.2024.100733_bib7","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1080\/17476348.2021.1916472","article-title":"Pulmonary fibrosis secondary to COVID-19: a narrative review","volume":"15","author":"Tanni","year":"2021","journal-title":"Expert Rev Respir Med"},{"key":"10.1016\/j.lana.2024.100733_bib8","doi-asserted-by":"crossref","first-page":"e222379","DOI":"10.1148\/radiol.222379","article-title":"Chronic pulmonary manifestations of COVID-19 infection: imaging evaluation","volume":"307","author":"Murphy","year":"2023","journal-title":"Radiology"},{"key":"10.1016\/j.lana.2024.100733_bib9","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1038\/s41590-021-01104-y","article-title":"Pathological sequelae of long-haul COVID","volume":"23","author":"Mehandru","year":"2022","journal-title":"Nat Immunol"},{"key":"10.1016\/j.lana.2024.100733_bib10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12931-021-01628-9","article-title":"Tracking the time course of pathological patterns of lung injury in severe COVID-19","volume":"22","author":"Mauad","year":"2021","journal-title":"Respir Res"},{"key":"10.1016\/j.lana.2024.100733_bib11","doi-asserted-by":"crossref","first-page":"e059110","DOI":"10.1136\/bmjopen-2021-059110","article-title":"Chronic lung lesions in COVID-19 survivors: predictive clinical model","volume":"12","author":"Carvalho","year":"2022","journal-title":"BMJ Open"},{"key":"10.1016\/j.lana.2024.100733_bib12","doi-asserted-by":"crossref","first-page":"E177","DOI":"10.1148\/radiol.2021203153","article-title":"Six-month follow-up chest CT findings after severe COVID-19 pneumonia","volume":"299","author":"Han","year":"2021","journal-title":"Radiology"},{"key":"10.1016\/j.lana.2024.100733_bib13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12931-022-02166-8","article-title":"Lung function and radiological findings 1 year after COVID-19: a prospective follow-up","volume":"23","author":"Tarraso","year":"2022","journal-title":"Respir Res"},{"key":"10.1016\/j.lana.2024.100733_bib14","first-page":"e280567","article-title":"Long-term respiratory follow-up of ICU hospitalized COVID-19 patients: prospective cohort study","volume":"18","author":"Carvalho","year":"2023","journal-title":"PLoS One"},{"key":"10.1016\/j.lana.2024.100733_bib15","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/S0140-6736(21)01755-4","article-title":"1-year outcomes in hospital survivors with COVID-19: a longitudinal cohort study","volume":"398","author":"Huang","year":"2021","journal-title":"Lancet"},{"key":"10.1016\/j.lana.2024.100733_bib16","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/S2213-2600(21)00174-0","article-title":"3-month, 6-month, 9-month, and 12-month respiratory outcomes in patients following COVID-19-related hospitalisation: a prospective study","volume":"9","author":"Wu","year":"2021","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.lana.2024.100733_bib17","doi-asserted-by":"crossref","first-page":"101668","DOI":"10.1016\/j.eclinm.2022.101668","article-title":"Lung-function trajectories in COVID-19 survivors after discharge: a two-year longitudinal cohort study","volume":"54","author":"Zhang","year":"2022","journal-title":"eClinicalMedicine"},{"key":"10.1016\/j.lana.2024.100733_bib18","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/S2213-2600(22)00126-6","article-title":"Health outcomes in people 2 years after surviving hospitalisation with COVID-19: a longitudinal cohort study","volume":"10","author":"Huang","year":"2022","journal-title":"Lancet Respir Med"},{"key":"10.1016\/j.lana.2024.100733_bib19","doi-asserted-by":"crossref","first-page":"e051706","DOI":"10.1136\/bmjopen-2021-051706","article-title":"Post-acute sequelae of SARS-CoV-2 infection (PASC): a protocol for a multidisciplinary prospective observational evaluation of a cohort of patients surviving hospitalisation in Sao Paulo, Brazil","volume":"11","author":"Busatto","year":"2021","journal-title":"BMJ Open"},{"key":"10.1016\/j.lana.2024.100733_bib20","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1164\/ajrccm\/144.5.1202","article-title":"Lung function testing: selection of reference values and interpretative strategies","volume":"144","year":"1991","journal-title":"Am Rev Respir Dis"},{"key":"10.1016\/j.lana.2024.100733_bib21","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1590\/S0100-879X1999000600006","article-title":"Reference values for lung function tests: I. Static volumes","volume":"32","author":"Neder","year":"1999","journal-title":"Braz J Med Biol Res"},{"key":"10.1016\/j.lana.2024.100733_bib22","first-page":"397","article-title":"Novos valores de refer\u00eancia para espirometria for\u00e7ada em brasileiros adultos de ra\u00e7a branca","volume":"33","author":"Pereira","year":"2007","journal-title":"J\u00a0Bras Pneumol"},{"key":"10.1016\/j.lana.2024.100733_bib23","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1590\/S0100-879X1999000600008","article-title":"Reference values for lung function tests: III. Carbon monoxide diffusing capacity (transfer factor)","volume":"32","author":"Neder","year":"1999","journal-title":"Braz J Med Biol Res"},{"key":"10.1016\/j.lana.2024.100733_bib24","doi-asserted-by":"crossref","first-page":"2680","DOI":"10.1080\/22221751.2022.2133639","article-title":"Healthy outcomes of patients with COVID-19 two years after the infection: a prospective cohort study","volume":"11","author":"Li","year":"2022","journal-title":"Emerg Microbes Infect"},{"key":"10.1016\/j.lana.2024.100733_bib25","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1016\/j.arbres.2023.08.006","article-title":"Long-term outcomes in critical COVID-19 survivors: a 2-year longitudinal cohort","volume":"59","author":"Gonz\u00e1lez","year":"2023","journal-title":"Arch Bronconeumol"},{"key":"10.1016\/j.lana.2024.100733_bib26","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1148\/radiol.212170","article-title":"Quantitative chest CT assessment of small airways disease in post-acute SARS-CoV-2 infection","volume":"304","author":"Cho","year":"2022","journal-title":"Radiology"},{"key":"10.1016\/j.lana.2024.100733_bib27","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.1038\/s41380-023-01951-1","article-title":"The phenotype and prediction of long-term physical, mental and cognitive COVID-19 sequelae 20 months after recovery, a community-based cohort study in China","volume":"28","author":"Zhao","year":"2023","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.lana.2024.100733_bib28","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.865845","article-title":"Identifying immunological and clinical predictors of COVID-19 severity and sequelae by mathematical modeling","volume":"13","author":"Elemam","year":"2022","journal-title":"Front Immunol"},{"key":"10.1016\/j.lana.2024.100733_bib29","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1038\/s41591-022-02156-9","article-title":"Comorbidities, multimorbidity and COVID-19","volume":"29","author":"Russell","year":"2023","journal-title":"Nat Med"},{"key":"10.1016\/j.lana.2024.100733_bib30","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1590\/S1807-59322011000600002","article-title":"Follow-up after acute respiratory distress syndrome caused by influenza a (H1N1) virus infection","volume":"66","author":"Toufen","year":"2011","journal-title":"Clinics"}],"container-title":["The Lancet Regional Health - Americas"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2667193X24000607?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2667193X24000607?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T05:17:23Z","timestamp":1715750243000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2667193X24000607"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":30,"alternative-id":["S2667193X24000607"],"URL":"https:\/\/doi.org\/10.1016\/j.lana.2024.100733","relation":{},"ISSN":["2667-193X"],"issn-type":[{"value":"2667-193X","type":"print"}],"subject":[],"published":{"date-parts":[[2024,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Post-COVID-19 respiratory sequelae two years after hospitalization: an ambidirectional study","name":"articletitle","label":"Article Title"},{"value":"The Lancet Regional Health - Americas","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lana.2024.100733","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"100733"}}