{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T21:03:50Z","timestamp":1790283830167,"version":"4.1.0"},"reference-count":9,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T00:00:00Z","timestamp":1756252800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100005224","name":"National Center for Immunization and Respiratory Diseases","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005224","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","thelancet.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Lancet Microbe"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.lanmic.2025.101240","type":"journal-article","created":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T19:53:54Z","timestamp":1765828434000},"page":"101240","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["A pandemic toolbox for clade 2.3.4.4b A(H5N1) influenza virus risk assessment"],"prefix":"10.1016","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0755-7368","authenticated-orcid":false,"given":"Jessica A","family":"Belser","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.lanmic.2025.101240_bib2","doi-asserted-by":"crossref","DOI":"10.1128\/jvi.00424-25","article-title":"Clade 2.3.4.4b highly pathogenic avian influenza H5N1 viruses: knowns, unknowns, and challenges","volume":"99","author":"Xie","year":"2025","journal-title":"J Virol"},{"key":"10.1016\/j.lanmic.2025.101240_bib3","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1093\/infdis\/jiae379","article-title":"An update on highly pathogenic avian influenza A(H5N1) virus, clade 2.3.4.4b","volume":"230","author":"Webby","year":"2024","journal-title":"J Infect Dis"},{"key":"10.1016\/j.lanmic.2025.101240_bib4","doi-asserted-by":"crossref","DOI":"10.1038\/s41591-025-03905-2","article-title":"Human infections with highly pathogenic avian influenza A(H5N1) viruses in the United States from March 2024 to May 2025","author":"Rolfes","year":"2025","journal-title":"Nat Med"},{"key":"10.1016\/j.lanmic.2025.101240_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.lanmic.2024.100973","article-title":"Pandemic risk characterisation of zoonotic influenza A viruses using the Tool for Influenza Pandemic Risk Assessment (TIPRA)","volume":"6","author":"Yamaji","year":"2025","journal-title":"Lancet Microbe"},{"key":"10.1016\/j.lanmic.2025.101240_bib6","first-page":"119","article-title":"Pandemic preparedness and the Influenza Risk Assessment Tool (IRAT)","volume":"385","author":"Cox","year":"2014","journal-title":"Curr Top Microbiol Immunol"},{"key":"10.1016\/j.lanmic.2025.101240_bib7","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.2353\/ajpath.2010.090949","article-title":"Seasonal and pandemic human influenza viruses attach better to human upper respiratory tract epithelium than avian influenza viruses","volume":"176","author":"van Riel","year":"2010","journal-title":"Am J Pathol"},{"key":"10.1016\/j.lanmic.2025.101240_bib8","article-title":"Attachment and replication of clade 2.3.4.4b influenza A(H5N1) viruses in human respiratory epithelium: an in vitro study","volume":"7","author":"Bauer","year":"2025","journal-title":"Lancet Microbe"},{"key":"10.1016\/j.lanmic.2025.101240_bib9","doi-asserted-by":"crossref","first-page":"E21","DOI":"10.1038\/s41586-025-08822-5","article-title":"Receptor-binding specificity of a bovine influenza A virus","volume":"640","author":"Chopra","year":"2025","journal-title":"Nature"},{"key":"10.1016\/j.lanmic.2025.101240_bib10","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.cell.2014.02.040","article-title":"Identification, characterization, and natural selection of mutations driving airborne transmission of A\/H5N1 virus","volume":"157","author":"Linster","year":"2014","journal-title":"Cell"}],"container-title":["The Lancet Microbe"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666524725001685?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666524725001685?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T20:56:38Z","timestamp":1790283398000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666524725001685"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["S2666524725001685"],"URL":"https:\/\/doi.org\/10.1016\/j.lanmic.2025.101240","relation":{},"ISSN":["2666-5247"],"issn-type":[{"value":"2666-5247","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A pandemic toolbox for clade 2.3.4.4b A(H5N1) influenza virus risk assessment","name":"articletitle","label":"Article Title"},{"value":"The Lancet Microbe","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lanmic.2025.101240","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.lanmic.2025.101230","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"101240"}}