{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T20:26:56Z","timestamp":1793046416454,"version":"4.5.0"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,1,18]],"date-time":"2023-01-18T00:00:00Z","timestamp":1674000000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["thelancet.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Lancet Regional Health - Southeast Asia"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.lansea.2023.100154","type":"journal-article","created":{"date-parts":[[2023,1,25]],"date-time":"2023-01-25T09:27:30Z","timestamp":1674638850000},"page":"100154","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Safety and efficacy of mycophenolate in COVID-19: a nonrandomised prospective study in western India"],"prefix":"10.1016","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1746-9801","authenticated-orcid":false,"given":"Atul","family":"Sajgure","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajit","family":"Kulkarni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atul","family":"Joshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4885-4649","authenticated-orcid":false,"given":"Vasanti","family":"Sajgure","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vaishali","family":"Pathak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0518-0787","authenticated-orcid":false,"given":"Rashida","family":"Melinkeri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shilpa","family":"Pathak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumit","family":"Agrawal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manoj","family":"Naik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milind","family":"Rajurkar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4695-5817","authenticated-orcid":false,"given":"Ameya","family":"Sajgure","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Girish","family":"Date","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.lansea.2023.100154_bib1","unstructured":"WHO Coronavirus (COVID-19) Dashboard. https:\/\/covid19.who.int\/. Date accessed: Jan 12, 2023."},{"key":"10.1016\/j.lansea.2023.100154_bib2","unstructured":"Estimating mortality from COVID-19. https:\/\/www.who.int\/publications\/i\/item\/WHO-2019-nCoV-Sci-Brief-Mortality-2020.1. Date accessed: April 26,\u00a02022."},{"key":"10.1016\/j.lansea.2023.100154_bib3","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.annepidem.2021.02.012","article-title":"COVID-19 fatality rates in hospitalized patients: systematic review and meta-analysis","volume":"57","author":"Macedo","year":"2021","journal-title":"Ann Epidemiol"},{"key":"10.1016\/j.lansea.2023.100154_bib4","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1002\/jmv.26232","article-title":"The cytokine storm and COVID-19","volume":"93","author":"Hu","year":"2021","journal-title":"J\u00a0Med Virol"},{"issue":"4","key":"10.1016\/j.lansea.2023.100154_bib5","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/j.chom.2021.02.020","article-title":"The variant gambit: COVID-19's next move","volume":"29","author":"Plante","year":"2021","journal-title":"Cell Host Microbe"},{"issue":"4","key":"10.1016\/j.lansea.2023.100154_bib6","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1080\/14787210.2021.1823832","article-title":"The effect of antivirals on COVID-19: a systematic review","volume":"19","author":"Hussain","year":"2021","journal-title":"Expert Rev Anti Infect Ther"},{"key":"10.1016\/j.lansea.2023.100154_bib7","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1016\/S0140-6736(20)32013-4","article-title":"Lopinavir\u2013ritonavir in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial","volume":"396","year":"2020","journal-title":"Lancet"},{"key":"10.1016\/j.lansea.2023.100154_bib8","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.ijid.2020.10.069","article-title":"Role of favipiravir in the treatment of COVID-19","volume":"102","author":"Joshi","year":"2021","journal-title":"Int J Infect Dis"},{"key":"10.1016\/j.lansea.2023.100154_bib9","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1056\/NEJMoa2007764","article-title":"Remdesivir for the treatment of covid-19 \u2014 final report","volume":"383","author":"Beigel","year":"2020","journal-title":"N\u00a0Engl J Med"},{"issue":"10","key":"10.1016\/j.lansea.2023.100154_bib10","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1001\/jama.2021.1225","article-title":"Monoclonal antibodies for COVID-19","volume":"325","author":"Lloyd","year":"2021","journal-title":"JAMA"},{"key":"10.1016\/j.lansea.2023.100154_bib11","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1002\/jmv.25801","article-title":"Tocilizumab treatment in COVID-19: a single center experience","volume":"92","author":"Luo","year":"2020","journal-title":"J\u00a0Med Virol"},{"key":"10.1016\/j.lansea.2023.100154_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2021.174579","article-title":"Use of steroids in COVID-19 patients: a meta-analysis","volume":"914","author":"Thakur","year":"2022","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.lansea.2023.100154_bib13","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1038\/s41392-020-0158-2","article-title":"A\u00a0retrospective cohort study of methylprednisolone therapy in severe patients with COVID-19 pneumonia","volume":"5","author":"Wang","year":"2020","journal-title":"Signal Transduct Target Ther"},{"key":"10.1016\/j.lansea.2023.100154_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2020.106560","article-title":"Towards treatment planning of COVID-19: rationale and hypothesis for the use of multiple immunosuppressive agents: anti-antibodies, immunoglobulins, and corticosteroids","volume":"84","author":"Saghazadeh","year":"2020","journal-title":"Int Immunopharmacol"},{"issue":"6","key":"10.1016\/j.lansea.2023.100154_bib15","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1016\/j.kint.2020.03.018","article-title":"COVID-19 in kidney transplant recipients","volume":"97","author":"Banerjee","year":"2020","journal-title":"Kidney Int"},{"issue":"6","key":"10.1016\/j.lansea.2023.100154_bib16","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1016\/j.kint.2020.04.002","article-title":"A\u00a0single center observational study of the clinical characteristics and short-term outcome of 20 kidney transplant patients admitted for SARS-CoV2 pneumonia","volume":"97","author":"Alberici","year":"2020","journal-title":"Kidney Int"},{"issue":"4","key":"10.1016\/j.lansea.2023.100154_bib17","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1097\/TP.0000000000003593","article-title":"Clinical profile and outcome of COVID-19 in 250 kidney transplant recipients","volume":"105","author":"Kute","year":"2020","journal-title":"Transplantation"},{"issue":"2","key":"10.1016\/j.lansea.2023.100154_bib18","first-page":"53","article-title":"Safety of mycophenolate in COVID-19: a case series","volume":"4","author":"Sajgure","year":"2021","journal-title":"J\u00a0Urol Nephrol Hepatol Sci"},{"key":"10.1016\/j.lansea.2023.100154_bib19","doi-asserted-by":"crossref","first-page":"S180","DOI":"10.1097\/01.tp.0000186390.10150.66","article-title":"Mechanisms of action of mycophenolate mofetil in preventing acute and chronic allograft rejection","volume":"80","author":"Allison","year":"2005","journal-title":"Transplantation"},{"issue":"4","key":"10.1016\/j.lansea.2023.100154_bib20","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1111\/j.1399-3062.2009.00407.x","article-title":"Mycophenolate mofetil: effects on cellular immune subsets, infectious complications, and antimicrobial activity","volume":"11","author":"Ritter","year":"2009","journal-title":"Transpl Infect Dis"},{"issue":"2","key":"10.1016\/j.lansea.2023.100154_bib21","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1006\/viro.2002.1685","article-title":"Mycophenolic acid inhibits dengue virus infection by preventing replication of viral RNA","volume":"304","author":"Diamond","year":"2002","journal-title":"Virology"},{"issue":"Pt 7","key":"10.1016\/j.lansea.2023.100154_bib22","doi-asserted-by":"crossref","first-page":"1947","DOI":"10.1099\/vir.0.81655-0","article-title":"Inhibition of dengue virus replication by mycophenolic acid and ribavirin","volume":"87","author":"Takhampuriya","year":"2006","journal-title":"J\u00a0Gen Virol"},{"key":"10.1016\/j.lansea.2023.100154_bib23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2180-3-25","article-title":"Mycophenolate mofetil inhibits the development of Coxsackie -B3-virus induced myocarditis in mice","volume":"3","author":"Padalko","year":"2003","journal-title":"BMC Microbiol"},{"issue":"1","key":"10.1016\/j.lansea.2023.100154_bib24","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0166-3542(02)00013-X","article-title":"Identification of active antiviral compounds against a New York isolate of West Nile virus","volume":"55","author":"Morrey","year":"2002","journal-title":"Antiviral Res"},{"issue":"2\u20133","key":"10.1016\/j.lansea.2023.100154_bib25","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/0166-3542(96)89697-5","article-title":"Use of the yellow fever virus vaccine strain 17D for the study of strategies for the treatment of yellow fever virus infections","volume":"30","author":"Neyts","year":"1996","journal-title":"Antiviral Res"},{"key":"10.1016\/j.lansea.2023.100154_bib26","first-page":"2025","article-title":"Highly active antiretroviral therapy with or without mycophenolate mofetil in treatment na\u00efve HIV-1 patients","volume":"21","author":"Sankatsingh","year":"2007","journal-title":"AIDS"},{"key":"10.1016\/j.lansea.2023.100154_bib27","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1111\/1348-0421.12828","article-title":"Antiviral activities of mycophenolic acid and IMD-0354 against SARS-CoV-2","volume":"64","author":"Kato","year":"2020","journal-title":"Microbiol Immunol"},{"key":"10.1016\/j.lansea.2023.100154_bib28","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.antiviral.2014.12.011","article-title":"Thiopurine analogs and mycophenolic acid synergistically inhibit the papain-like protease of Middle East respiratory syndrome coronavirus","volume":"115","author":"Cheng","year":"2015","journal-title":"Antiviral Res"},{"key":"10.1016\/j.lansea.2023.100154_bib29","unstructured":"NEWS (or NEWS2) Score When Assessing Possible COVID-19 Patients in Primary Care? [Internet]. CEBM. [cited 2020 Aug 8]. Available from: https:\/\/www.cebm.net\/covid-19\/should-we-use-the-news-or-news2-score-when-assessing-patients-with-possible-covid-19-in-primary-care\/. Date accessed: October 28,\u00a02022."},{"issue":"1","key":"10.1016\/j.lansea.2023.100154_bib30","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1016\/j.jhep.2020.07.040","article-title":"Epidemiological pattern, incidence, and outcomes of COVID-19 in liver transplant patients","volume":"74","author":"Colmenero","year":"2021","journal-title":"J\u00a0Hepatol"},{"key":"10.1016\/j.lansea.2023.100154_bib31","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.1365-3083.1991.tb03746.x","article-title":"Lymphocyte selective cytostatic and immunosuppressive effects of mycophenolic acid in-vitro: role of deoyguanosine depletion","volume":"33","author":"Eugui","year":"1991","journal-title":"Scand J Immunol"},{"key":"10.1016\/j.lansea.2023.100154_bib32","doi-asserted-by":"crossref","first-page":"27286","DOI":"10.1016\/S0021-9258(19)74247-1","article-title":"Characterization of human type I and type II IMP dehydrogenases","volume":"268","author":"Carr","year":"1993","journal-title":"J\u00a0Biol Chem"},{"issue":"Suppl 17","key":"10.1016\/j.lansea.2023.100154_bib33","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/j.1399-0012.2006.00597.x","article-title":"Antifibrotic actions of mycophenolic acid","volume":"20","author":"Morath","year":"2006","journal-title":"Clin Transplant"}],"container-title":["The Lancet Regional Health - Southeast Asia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772368223000148?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772368223000148?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T09:50:19Z","timestamp":1757411419000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2772368223000148"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":33,"alternative-id":["S2772368223000148"],"URL":"https:\/\/doi.org\/10.1016\/j.lansea.2023.100154","relation":{},"ISSN":["2772-3682"],"issn-type":[{"value":"2772-3682","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Safety and efficacy of mycophenolate in COVID-19: a nonrandomised prospective study in western India","name":"articletitle","label":"Article Title"},{"value":"The Lancet Regional Health - Southeast Asia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lansea.2023.100154","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"100154"}}