{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T05:53:38Z","timestamp":1793253218353,"version":"4.5.0"},"reference-count":22,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T00:00:00Z","timestamp":1694390400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000272","name":"NIHR","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["thelancet.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Lancet Regional Health - Southeast Asia"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.1016\/j.lansea.2023.100284","type":"journal-article","created":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T07:15:50Z","timestamp":1696403750000},"page":"100284","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Duration of birth depression and neurodevelopmental outcomes after whole-body hypothermia for hypoxic ischemic encephalopathy in India, Sri Lanka and Bangladesh \u2013 an exploratory analysis of the HELIX trial"],"prefix":"10.1016","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7789-1003","authenticated-orcid":false,"given":"Constance","family":"Burgod","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Munirah","family":"Mazlan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stuti","family":"Pant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vaisakh","family":"Krishnan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reema","family":"Garegrat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Montaldo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pallavi","family":"Muraleedharan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prathik","family":"Bandiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chinnathambi N.","family":"Kamalaratnam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rema","family":"Chandramohan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swati","family":"Manerkar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ismat","family":"Jahan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sadeka C.","family":"Moni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammod","family":"Shahidullah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ranmali","family":"Rodrigo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samanmali","family":"Sumanasena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radhika","family":"Sujatha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Babu Peter","family":"Sathyanathan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2494-8512","authenticated-orcid":false,"given":"Anagha R.","family":"Joshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronit R.","family":"Pressler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Bassett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seetha","family":"Shankaran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8795-5165","authenticated-orcid":false,"given":"Sudhin","family":"Thayyil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"12","key":"10.1016\/j.lansea.2023.100284_bib1","doi-asserted-by":"crossref","DOI":"10.1136\/bmjgh-2022-010294","article-title":"Incidence and outcomes of intrapartum-related neonatal encephalopathy in low-income and middle-income countries: a systematic review and meta-analysis","volume":"7","author":"Kukka","year":"2022","journal-title":"BMJ Glob Health"},{"issue":"6","key":"10.1016\/j.lansea.2023.100284_bib2","first-page":"409","article-title":"No cry at birth: global estimates of intrapartum stillbirths and intrapartum-related neonatal deaths","volume":"83","author":"Lawn","year":"2005","journal-title":"Bull World Health Organ"},{"issue":"6","key":"10.1016\/j.lansea.2023.100284_bib3","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.earlhumdev.2010.05.010","article-title":"Epidemiology of neonatal encephalopathy and hypoxic-ischaemic encephalopathy","volume":"86","author":"Kurinczuk","year":"2010","journal-title":"Early Hum Dev"},{"issue":"15","key":"10.1016\/j.lansea.2023.100284_bib4","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1056\/NEJMcps050929","article-title":"Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy","volume":"353","author":"Shankaran","year":"2005","journal-title":"N\u00a0Engl J Med"},{"issue":"14","key":"10.1016\/j.lansea.2023.100284_bib5","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1056\/NEJMoa0900854","article-title":"Moderate hypothermia to treat perinatal asphyxial encephalopathy","volume":"361","author":"Azzopardi","year":"2009","journal-title":"N\u00a0Engl J Med"},{"issue":"9460","key":"10.1016\/j.lansea.2023.100284_bib6","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/S0140-6736(05)17946-X","article-title":"Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial","volume":"365","author":"Gluckman","year":"2005","journal-title":"Lancet"},{"issue":"8","key":"10.1016\/j.lansea.2023.100284_bib7","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1001\/archpediatrics.2011.43","article-title":"Whole-body hypothermia for term and near-term newborns with hypoxic-ischemic encephalopathy: a randomized controlled trial","volume":"165","author":"Jacobs","year":"2011","journal-title":"Arch Pediatr Adolesc Med"},{"issue":"9","key":"10.1016\/j.lansea.2023.100284_bib8","doi-asserted-by":"crossref","first-page":"e1273","DOI":"10.1016\/S2214-109X(21)00264-3","article-title":"Hypothermia for moderate or severe neonatal encephalopathy in low-income and middle-income countries (HELIX): a randomised controlled trial in India, Sri Lanka, and Bangladesh","volume":"9","author":"Thayyil","year":"2021","journal-title":"Lancet Glob Health"},{"issue":"1","key":"10.1016\/j.lansea.2023.100284_bib9","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S1474-4422(18)30325-9","article-title":"Magnetic resonance spectroscopy assessment of brain injury after moderate hypothermia in neonatal encephalopathy: a prospective multicentre cohort study","volume":"18","author":"Lally","year":"2019","journal-title":"Lancet Neurol"},{"issue":"2","key":"10.1016\/j.lansea.2023.100284_bib10","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1177\/0734282906297199","article-title":"Test review: Bayley, N. (2006). Bayley Scales of infant and toddler development\u2013 third edition. San antonio, TX: harcourt assessment","volume":"25","author":"Albers","year":"2007","journal-title":"J\u00a0Psychoeduc Assess"},{"issue":"4","key":"10.1016\/j.lansea.2023.100284_bib11","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1111\/j.1469-8749.2008.02045.x","article-title":"Development of the gross motor function classification system for cerebral palsy","volume":"50","author":"Rosenbaum","year":"2008","journal-title":"Dev Med Child Neurol"},{"key":"10.1016\/j.lansea.2023.100284_bib12","series-title":"Child growth standards","year":"2009"},{"issue":"5","key":"10.1016\/j.lansea.2023.100284_bib13","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2023.12152","article-title":"Whole-body hypothermia, cerebral magnetic resonance biomarkers, and outcomes in neonates with moderate or severe hypoxic-ischemic encephalopathy born at tertiary care centers vs other facilities: a nested study within a randomized clinical trial","volume":"6","author":"Thayyil","year":"2023","journal-title":"JAMA Netw Open"},{"key":"10.1016\/j.lansea.2023.100284_bib14","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.seizure.2015.10.007","article-title":"The temporal characteristics of seizures in neonatal hypoxic ischemic encephalopathy treated with hypothermia","volume":"33","author":"Lynch","year":"2015","journal-title":"Seizure"},{"key":"10.1016\/j.lansea.2023.100284_bib15","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1172\/JCI119153","article-title":"Dramatic neuronal rescue with prolonged selective head cooling after ischemia in fetal lambs","volume":"99 2","author":"Gunn","year":"1997","journal-title":"J\u00a0Clin Invest"},{"issue":"8399","key":"10.1016\/j.lansea.2023.100284_bib16","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/S0140-6736(84)90539-7","article-title":"Cerebral energy metabolism studied with phosphorus NMR spectroscopy in normal and birth-asphyxiated infants","volume":"2","author":"Hope","year":"1984","journal-title":"Lancet"},{"issue":"5","key":"10.1016\/j.lansea.2023.100284_bib17","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1203\/00006450-199505000-00019","article-title":"Mild hypothermia after severe transient hypoxia-ischemia ameliorates delayed cerebral energy failure in the newborn piglet","volume":"37","author":"Thoresen","year":"1995","journal-title":"Pediatr Res"},{"issue":"6","key":"10.1016\/j.lansea.2023.100284_bib18","doi-asserted-by":"crossref","first-page":"F473","DOI":"10.1136\/archdischild-2013-303692","article-title":"Apgar scores at 10 min and outcomes at 6-7 years following hypoxic-ischaemic encephalopathy","volume":"98","author":"Natarajan","year":"2013","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"issue":"4","key":"10.1016\/j.lansea.2023.100284_bib19","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2021-054992","article-title":"Predictive ability of 10-minute apgar scores for mortality and neurodevelopmental disability","volume":"149","author":"Shukla","year":"2022","journal-title":"Pediatrics"},{"issue":"16_suppl_1","key":"10.1016\/j.lansea.2023.100284_bib20","doi-asserted-by":"crossref","first-page":"S185","DOI":"10.1161\/CIR.0000000000000895","article-title":"Neonatal life support: 2020 international consensus on cardiopulmonary resuscitation and emergency cardiovascular care science with treatment recommendations","volume":"142","author":"Wyckoff","year":"2020","journal-title":"Circulation"},{"key":"10.1016\/j.lansea.2023.100284_bib21","series-title":"Valuing disease burden due to neonatal encephalopathy and birth trauma: a health economic evaluation","author":"Vidavalur","year":"2023"},{"issue":"8","key":"10.1016\/j.lansea.2023.100284_bib22","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0073895","article-title":"Pre-existing hypoxia is associated with greater EEG suppression and early onset of evolving seizure activity during brief repeated asphyxia in near-term fetal sheep","volume":"8","author":"Wassink","year":"2013","journal-title":"PLoS One"}],"container-title":["The Lancet Regional Health - Southeast Asia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772368223001440?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772368223001440?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T09:52:17Z","timestamp":1757411537000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2772368223001440"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":22,"alternative-id":["S2772368223001440"],"URL":"https:\/\/doi.org\/10.1016\/j.lansea.2023.100284","relation":{},"ISSN":["2772-3682"],"issn-type":[{"value":"2772-3682","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Duration of birth depression and neurodevelopmental outcomes after whole-body hypothermia for hypoxic ischemic encephalopathy in India, Sri Lanka and Bangladesh \u2013 an exploratory analysis of the HELIX trial","name":"articletitle","label":"Article Title"},{"value":"The Lancet Regional Health - Southeast Asia","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lansea.2023.100284","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"100284"}}