{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T05:03:13Z","timestamp":1780462993065,"version":"3.54.1"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,10,25]],"date-time":"2023-10-25T00:00:00Z","timestamp":1698192000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004826","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004826","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005088","name":"Beijing Municipal Health Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005088","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["thelancet.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Lancet Regional Health - Western Pacific"],"published-print":{"date-parts":[[2024,1]]},"DOI":"10.1016\/j.lanwpc.2023.100962","type":"journal-article","created":{"date-parts":[[2023,11,17]],"date-time":"2023-11-17T06:17:05Z","timestamp":1700201825000},"page":"100962","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Cost-effectiveness of treatment in adults with blood pressure of 130\u2013139\/80\u201389\u00a0mmHg and high cardiovascular risk in China: a modelling study"],"prefix":"10.1016","volume":"42","author":[{"given":"Jiangtao","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3239-3449","authenticated-orcid":false,"given":"Dong","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuohua","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7095-6022","authenticated-orcid":false,"given":"Shouling","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6709-7041","authenticated-orcid":false,"given":"Yue","family":"Qi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10060","key":"10.1016\/j.lanwpc.2023.100962_bib1","doi-asserted-by":"crossref","first-page":"2665","DOI":"10.1016\/S0140-6736(16)31134-5","article-title":"A\u00a0call to action and a lifecourse strategy to address the global burden of raised blood pressure on current and future generations: the Lancet Commission on hypertension","volume":"388","author":"Olsen","year":"2016","journal-title":"Lancet"},{"issue":"5","key":"10.1016\/j.lanwpc.2023.100962_bib2","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1111\/jch.14225","article-title":"Blood pressure and long-term subclinical cardiovascular outcomes in low-risk young adults: Insights from Hanzhong adolescent hypertension cohort","volume":"23","author":"Yan","year":"2021","journal-title":"J\u00a0Clin Hypertens (Greenwich)"},{"key":"10.1016\/j.lanwpc.2023.100962_bib3","article-title":"Association between high blood pressure and long term cardiovascular events in young adults: systematic review and meta-analysis","volume":"370","author":"Luo","year":"2020","journal-title":"BMJ"},{"issue":"4","key":"10.1016\/j.lanwpc.2023.100962_bib4","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1097\/HJH.0000000000002321","volume":"38","author":"Han","year":"2020","journal-title":"J\u00a0Hypertens"},{"issue":"3","key":"10.1016\/j.lanwpc.2023.100962_bib5","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1177\/2047487313516563","article-title":"Lifetime risk for cardiovascular disease in a Chinese population: the Chinese Multi-Provincial Cohort Study","volume":"22","author":"Wang","year":"2015","journal-title":"Eur J Prev Cardiol"},{"issue":"11","key":"10.1016\/j.lanwpc.2023.100962_bib6","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1016\/j.jacc.2018.06.056","article-title":"Long-term cardiovascular risk associated with stage 1 hypertension defined by the 2017 ACC\/AHA hypertension guideline","volume":"72","author":"Qi","year":"2018","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"10285","key":"10.1016\/j.lanwpc.2023.100962_bib7","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1016\/S0140-6736(21)00590-0","article-title":"Pharmacological blood pressure lowering for primary and secondary prevention of cardiovascular disease across different levels of blood pressure: an individual participant-level data meta-analysis","volume":"397","year":"2021","journal-title":"Lancet"},{"issue":"25","key":"10.1016\/j.lanwpc.2023.100962_bib8","doi-asserted-by":"crossref","first-page":"2429","DOI":"10.1056\/NEJMoa1804492","article-title":"Global, Regional, and country-specific lifetime risks of stroke, 1990 and 2016","volume":"379","author":"Feigin","year":"2018","journal-title":"N\u00a0Engl J Med"},{"issue":"8","key":"10.1016\/j.lanwpc.2023.100962_bib9","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1111\/jch.13609","article-title":"Clinical outcomes and economic impact of the 2017 ACC\/AHA guidelines on hypertension in China","volume":"21","author":"Wang","year":"2019","journal-title":"J\u00a0Clin Hypertens (Greenwich)"},{"issue":"19","key":"10.1016\/j.lanwpc.2023.100962_bib10","doi-asserted-by":"crossref","first-page":"2199","DOI":"10.1016\/j.jacc.2017.11.005","volume":"71","author":"Whelton","year":"2018","journal-title":"J\u00a0Am Coll Cardiol"},{"issue":"33","key":"10.1016\/j.lanwpc.2023.100962_bib11","doi-asserted-by":"crossref","first-page":"3021","DOI":"10.1093\/eurheartj\/ehy339","article-title":"2018 ESC\/ESH Guidelines for the management of arterial hypertension","volume":"39","author":"Williams","year":"2018","journal-title":"Eur Heart J"},{"key":"10.1016\/j.lanwpc.2023.100962_bib13","first-page":"579","article-title":"Writing group of Chinese guidelines for the management of hypertension. 2018 Chinese guidelines for the management of hypertension","volume":"19","year":"2019","journal-title":"Prevent Treatment Cardiovasc Cerebrovasc Dis"},{"issue":"3","key":"10.1016\/j.lanwpc.2023.100962_bib14","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1161\/HYPERTENSIONAHA.119.14533","article-title":"Cost-effectiveness of drug treatment for Chinese patients with stage I hypertension according to the 2017 hypertension clinical practice guidelines","volume":"76","author":"Zhou","year":"2020","journal-title":"Hypertension"},{"key":"10.1016\/j.lanwpc.2023.100962_bib15","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.ijcard.2017.05.003","article-title":"Potential health impact and cost-effectiveness of drug therapy for prehypertension","volume":"240","author":"Chen","year":"2017","journal-title":"Int J Cardiol"},{"issue":"8","key":"10.1016\/j.lanwpc.2023.100962_bib16","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1001860","article-title":"The cost-effectiveness of low-cost essential antihypertensive medicines for hypertension control in China: a modelling study","volume":"12","author":"Gu","year":"2015","journal-title":"PLoS Med"},{"issue":"5","key":"10.1016\/j.lanwpc.2023.100962_bib17","first-page":"330","article-title":"Hypertension screening and follow-up management by primary health care system among Chinese population aged 35 Years and above","volume":"28","author":"Feng","year":"2015","journal-title":"Biomed Environ Sci"},{"issue":"3","key":"10.1016\/j.lanwpc.2023.100962_bib18","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1038\/s41440-021-00774-3","article-title":"Cost-effectiveness analysis of intensive blood pressure control in Korea","volume":"45","author":"Lee","year":"2022","journal-title":"Hypertens Res"},{"key":"10.1016\/j.lanwpc.2023.100962_bib19","series-title":"China health Statistics Yearbook 2022","year":"2022"},{"issue":"2","key":"10.1016\/j.lanwpc.2023.100962_bib20","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.jval.2013.02.010","article-title":"Consolidated health economic evaluation reporting standards (CHEERS) statement","volume":"16","author":"Husereau","year":"2013","journal-title":"Value Health"},{"issue":"7","key":"10.1016\/j.lanwpc.2023.100962_bib21","article-title":"Stage 1 hypertension and the 10-year and lifetime risk of cardiovascular disease: a prospective Real-world study","volume":"12","author":"Peng","year":"2023","journal-title":"J\u00a0Am Heart Assoc"},{"issue":"12","key":"10.1016\/j.lanwpc.2023.100962_bib22","first-page":"1000","article-title":"[Chinese guideline on the primary prevention of cardiovascular diseases]","volume":"48","year":"2020","journal-title":"Zhonghua Xin Xue Guan Bing Za Zhi"},{"issue":"11\u201312","key":"10.1016\/j.lanwpc.2023.100962_bib23","doi-asserted-by":"crossref","first-page":"1495","DOI":"10.1002\/(SICI)1097-0258(20000615\/30)19:11\/12<1495::AID-SIM441>3.0.CO;2-E","article-title":"Computing estimates of incidence, including lifetime risk: Alzheimer's disease in the Framingham Study. The Practical Incidence Estimators (PIE) macro","volume":"19","author":"Beiser","year":"2000","journal-title":"Stat Med"},{"issue":"12","key":"10.1016\/j.lanwpc.2023.100962_bib24","doi-asserted-by":"crossref","first-page":"2434","DOI":"10.1097\/HJH.0000000000001084","article-title":"Lifetime risk of stroke in young-aged and middle-aged Chinese population: the Chinese Multi-Provincial Cohort Study","volume":"34","author":"Wang","year":"2016","journal-title":"J\u00a0Hypertens"},{"issue":"10","key":"10.1016\/j.lanwpc.2023.100962_bib25","doi-asserted-by":"crossref","first-page":"2361","DOI":"10.1161\/01.STR.0000089017.90037.7A","article-title":"Long-term mortality and recurrent stroke risk among Chinese stroke patients with predominant intracranial atherosclerosis","volume":"34","author":"Wong","year":"2003","journal-title":"Stroke"},{"issue":"5","key":"10.1016\/j.lanwpc.2023.100962_bib26","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1161\/STROKEAHA.111.000302","article-title":"Association of hypertension with stroke recurrence depends on ischemic stroke subtype","volume":"44","author":"Wang","year":"2013","journal-title":"Stroke"},{"issue":"2","key":"10.1016\/j.lanwpc.2023.100962_bib27","first-page":"247","article-title":"Self-rated health status and risk of incident stroke in 0.5 million Chinese adults: the China Kadoorie Biobank study","volume":"20","author":"Dong","year":"2018","journal-title":"J\u00a0Stroke"},{"key":"10.1016\/j.lanwpc.2023.100962_bib28","first-page":"580","article-title":"Rrisk factors associated with increased end points of patients with non-ST elevation acute coronary syndromes in China: 2 years follow up results of China-OASIS registry","volume":"37","author":"Liang","year":"2009","journal-title":"Zhonghua Xin Xue Guan Bing Za Zhi"},{"issue":"9","key":"10.1016\/j.lanwpc.2023.100962_bib29","article-title":"Association between medication adherence and 1-year major cardiovascular adverse events after acute myocardial infarction in China","volume":"8","author":"Shang","year":"2019","journal-title":"J\u00a0Am Heart Assoc"},{"issue":"7","key":"10.1016\/j.lanwpc.2023.100962_bib30","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1111\/j.1532-5415.2007.01230.x","article-title":"Effect of xuezhikang on cardiovascular events and mortality in elderly patients with a history of myocardial infarction: a subgroup analysis of elderly subjects from the China Coronary Secondary Prevention Study","volume":"55","author":"Ye","year":"2007","journal-title":"J\u00a0Am Geriatr Soc"},{"issue":"16","key":"10.1016\/j.lanwpc.2023.100962_bib31","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1056\/NEJMoa060838","article-title":"Feasibility of treating prehypertension with an angiotensin-receptor blocker","volume":"354","author":"Julius","year":"2006","journal-title":"N\u00a0Engl J Med"},{"issue":"2","key":"10.1016\/j.lanwpc.2023.100962_bib32","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1097\/HJH.0b013e328333b009","article-title":"Perindopril-based blood pressure lowering reduces major vascular events in Asian and Western participants with cerebrovascular disease: the PROGRESS trial","volume":"28","author":"Arima","year":"2010","journal-title":"J\u00a0Hypertens"},{"issue":"10022","key":"10.1016\/j.lanwpc.2023.100962_bib33","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1016\/S0140-6736(15)01225-8","article-title":"Blood pressure lowering for prevention of cardiovascular disease and death: a systematic review and meta-analysis","volume":"387","author":"Ettehad","year":"2016","journal-title":"Lancet"},{"issue":"9","key":"10.1016\/j.lanwpc.2023.100962_bib34","doi-asserted-by":"crossref","first-page":"768","DOI":"10.5603\/KP.a2015.0089","article-title":"Economic evaluation of single-pill combination of indapamide and amlodipine in the treatment of arterial hypertension in the Polish setting","volume":"73","author":"Kawalec","year":"2015","journal-title":"Kardiol Pol"},{"issue":"15","key":"10.1016\/j.lanwpc.2023.100962_bib35","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1001\/jama.1996.03540150055031","article-title":"Recommendations of the panel on cost-effectiveness in health and medicine","volume":"276","author":"Weinstein","year":"1996","journal-title":"JAMA"},{"issue":"10112","key":"10.1016\/j.lanwpc.2023.100962_bib36","doi-asserted-by":"crossref","first-page":"2559","DOI":"10.1016\/S0140-6736(17)32476-5","article-title":"Availability, cost, and prescription patterns of antihypertensive medications in primary health care in China: a nationwide cross-sectional survey","volume":"390","author":"Su","year":"2017","journal-title":"Lancet"},{"issue":"7404","key":"10.1016\/j.lanwpc.2023.100962_bib38","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1136\/bmj.326.7404.1427","article-title":"Value of low dose combination treatment with blood pressure lowering drugs: analysis of 354 randomised trials","volume":"326","author":"Law","year":"2003","journal-title":"BMJ"},{"key":"10.1016\/j.lanwpc.2023.100962_bib39","author":"Department of Primary Health of National Health Commission"},{"issue":"5","key":"10.1016\/j.lanwpc.2023.100962_bib41","first-page":"75","article-title":"Economic burden among cardiovascular patients of middle-aged and elderly: an empirical analysis based on China Health and Retirement Longitudinal Survey data","volume":"10","author":"Li","year":"2017","journal-title":"Chinese J Health Policy"},{"key":"10.1016\/j.lanwpc.2023.100962_bib42","series-title":"The study on the economic burden of stroke patients and its influencing factors in Henan province [MPH thesis]","author":"Wang","year":"2017"},{"issue":"9798","key":"10.1016\/j.lanwpc.2023.100962_bib46","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1016\/S0140-6736(11)61215-4","article-title":"Use of secondary prevention drugs for cardiovascular disease in the community in high-income, middle-income, and low-income countries (the PURE Study): a prospective epidemiological survey","volume":"378","author":"Yusuf","year":"2011","journal-title":"Lancet"},{"issue":"12","key":"10.1016\/j.lanwpc.2023.100962_bib47","doi-asserted-by":"crossref","first-page":"e897","DOI":"10.1016\/S2468-2667(21)00228-0","article-title":"Temporal trend and attributable risk factors of stroke burden in China, 1990-2019: an analysis for the Global Burden of Disease Study 2019","volume":"6","author":"Ma","year":"2021","journal-title":"Lancet Public Health"},{"issue":"7","key":"10.1016\/j.lanwpc.2023.100962_bib49","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1097\/HJH.0000000000002073","article-title":"Blood pressure levels and risk of cardiovascular disease mortality among Japanese men and women: the Japan Collaborative Cohort Study for Evaluation of Cancer Risk (JACC Study)","volume":"37","author":"Yamagishi","year":"2019","journal-title":"J\u00a0Hypertens"},{"issue":"1","key":"10.1016\/j.lanwpc.2023.100962_bib50","doi-asserted-by":"crossref","first-page":"43","DOI":"10.5334\/gh.830","article-title":"Impact of China's low centralized medicine procurement prices on the cost-effectiveness of statins for the primary prevention of atherosclerotic cardiovascular disease","volume":"15","author":"Wang","year":"2020","journal-title":"Glob Heart"},{"key":"10.1016\/j.lanwpc.2023.100962_bib51","article-title":"Association between antihypertensive treatment and adverse events: systematic review and meta-analysis","volume":"372","author":"Albasri","year":"2021","journal-title":"BMJ"},{"issue":"10305","key":"10.1016\/j.lanwpc.2023.100962_bib52","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1016\/S0140-6736(21)01921-8","article-title":"Age-stratified and blood-pressure-stratified effects of blood-pressure-lowering pharmacotherapy for the prevention of cardiovascular disease and death: an individual participant-level data meta-analysis","volume":"398","year":"2021","journal-title":"Lancet"}],"container-title":["The Lancet Regional Health - Western Pacific"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666606523002808?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666606523002808?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T02:43:04Z","timestamp":1763001784000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666606523002808"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":45,"alternative-id":["S2666606523002808"],"URL":"https:\/\/doi.org\/10.1016\/j.lanwpc.2023.100962","relation":{},"ISSN":["2666-6065"],"issn-type":[{"value":"2666-6065","type":"print"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cost-effectiveness of treatment in adults with blood pressure of 130\u2013139\/80\u201389\u00a0mmHg and high cardiovascular risk in China: a modelling study","name":"articletitle","label":"Article Title"},{"value":"The Lancet Regional Health - Western Pacific","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lanwpc.2023.100962","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"100962"}}