{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T10:48:25Z","timestamp":1790246905590,"version":"4.1.0"},"reference-count":49,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2004,7,1]],"date-time":"2004-07-01T00:00:00Z","timestamp":1088640000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Leukemia Research"],"published-print":{"date-parts":[[2004,7]]},"DOI":"10.1016\/j.leukres.2003.11.010","type":"journal-article","created":{"date-parts":[[2004,2,6]],"date-time":"2004-02-06T10:17:37Z","timestamp":1076062657000},"page":"713-724","source":"Crossref","is-referenced-by-count":58,"title":["Population-based study of lymphoma in Germany: rationale, study design and first results"],"prefix":"10.1016","volume":"28","author":[{"given":"Nikolaus","family":"Becker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelin","family":"Deeg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Nieters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.leukres.2003.11.010_BIB1","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1002\/ijc.1440","article-title":"Estimating the world cancer burden: Globocan 2000","volume":"94","author":"Parkin","year":"2001","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.leukres.2003.11.010_BIB2","unstructured":"Scherr PA, Mueller NE. Non-Hodgkin\u2019s lymphomas. In: Schottenfeld D, Fraumeni Jr JF, editors. Cancer epidemiology and prevention. 2nd edition. New York: Oxford University Press; 1996."},{"key":"10.1016\/j.leukres.2003.11.010_BIB3","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1097\/00001622-200009000-00002","article-title":"Epidemiology of lymphomas","volume":"12","author":"Baris","year":"2000","journal-title":"Curr. Opin. Oncol."},{"key":"10.1016\/j.leukres.2003.11.010_BIB4","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1182\/blood.V84.5.1361.1361","article-title":"A revised European\u2013American classification of lymphoid neoplasms: a proposal from the International Lymphoma Study Group","volume":"84","author":"Harris","year":"1994","journal-title":"Blood"},{"key":"10.1016\/j.leukres.2003.11.010_BIB5","unstructured":"Jaffe ES, Harris NL, Stein H, Vardiman JW. Pathology and genetics of tumours of haematopoietic and lymphoid tissues. International Agency for Research on Cancer. Lyon: IARC Press; 2001."},{"issue":"2","key":"10.1016\/j.leukres.2003.11.010_BIB6","first-page":"120","article-title":"Speculations on the cause of childhood acute lymphoblastic leukemia","volume":"2","author":"Greaves","year":"1988","journal-title":"Leukemia"},{"key":"10.1016\/j.leukres.2003.11.010_BIB7","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/S0140-6736(96)09412-3","article-title":"Aetiology of acute leukaemia","volume":"349","author":"Greaves","year":"1997","journal-title":"Lancet"},{"key":"10.1016\/j.leukres.2003.11.010_BIB8","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1136\/bmj.299.6710.1259","article-title":"Hay fever","volume":"299","author":"Strachan","year":"1989","journal-title":"Br. Med. J."},{"key":"10.1016\/j.leukres.2003.11.010_BIB9","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1146\/annurev.iy.12.040194.001303","article-title":"Lymphokine production by human T cells in disease states","volume":"12","author":"Romagnani","year":"1994","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.leukres.2003.11.010_BIB10","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1111\/j.1398-9995.1998.tb04951.x","article-title":"The Th1\/Th2 paradigm and allergic disorders","volume":"53","author":"Romagnani","year":"1998","journal-title":"Allergy"},{"key":"10.1016\/j.leukres.2003.11.010_BIB11","unstructured":"Bolm-Audorff U, Ahrens W, J\u00f6ckel K-H, Molik B, Greiser E, Timm J, et al. Experience with supplementary questionnaires in a lung cancer case-referent study. In: Hemon D, Goldberg M, editors. Proceedings of the Workshop on Methodology of Assessment of Occupational Exposures in the Context of Epidemiological Detection of Cancer Risks, Paris, 18\u201319 February 1988. Luxembourg: Office of the Official Publications of the European Communities; 1989. p. 117\u201368."},{"key":"10.1016\/j.leukres.2003.11.010_BIB12","unstructured":"Breslow NE, Day NE. Statistical methods in cancer research. The analysis of case\u2013control studies, vol. 1. Lyon: IARC Scientific Publication; 1980."},{"key":"10.1016\/j.leukres.2003.11.010_BIB13","doi-asserted-by":"crossref","first-page":"251","DOI":"10.3109\/10428199709051774","article-title":"Interleukin-10 in non-Hodgkin\u2019s lymphoma","volume":"26","author":"Cortes","year":"1997","journal-title":"Leuk Lymphoma"},{"key":"10.1016\/j.leukres.2003.11.010_BIB14","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1007\/s00262-001-0232-8","article-title":"T-helper (Th)1\/Th2 imbalance in patients with previously untreated B-cell diffuse large cell lymphoma","volume":"50","author":"Mori","year":"2001","journal-title":"Cancer Immunol. Immunother."},{"key":"10.1016\/j.leukres.2003.11.010_BIB15","doi-asserted-by":"crossref","first-page":"4283","DOI":"10.1182\/blood-2002-01-0099","article-title":"The role of cytokines in classical Hodgkin lymphoma","volume":"99","author":"Skinnider","year":"2002","journal-title":"Blood"},{"key":"10.1016\/j.leukres.2003.11.010_BIB16","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1016\/S0140-6736(01)06252-3","article-title":"ALEX study team. Exposure to farming in early life and development of asthma and allergy: a cross-sectional survey","volume":"358","author":"Riedler","year":"2001","journal-title":"Lancet"},{"key":"10.1016\/j.leukres.2003.11.010_BIB17","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1126\/science.296.5567.490","article-title":"Allergy, parasites, and the hygiene hypothesis","volume":"296","author":"Yazdanbakhsh","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.leukres.2003.11.010_BIB18","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/S0140-6736(02)09641-1","article-title":"ALEX study group. Expression of CD14 and Toll-like receptor 2 in farmers\u2019 and non-farmers\u2019 children","volume":"360","author":"Lauener","year":"2002","journal-title":"Lancet"},{"key":"10.1016\/j.leukres.2003.11.010_BIB19","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1067\/mai.2002.122157","article-title":"Endotoxin exposure in allergy and asthma: reconciling a paradox","volume":"109","author":"Liu","year":"2002","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.leukres.2003.11.010_BIB20","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1093\/oxfordjournals.aje.a112811","article-title":"Leukemia among Nebraska farmers: a death certificate study","volume":"110","author":"Blair","year":"1979","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.leukres.2003.11.010_BIB21","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1111\/j.1365-2141.1995.tb05261.x","article-title":"Hairy cell leukaemia, occupation, and smoking","volume":"91","author":"Clavel","year":"1995","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.leukres.2003.11.010_BIB22","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1007\/s004200100248","article-title":"Non-Hodgkin\u2019s lymphomas and occupation in Sweden","volume":"74","author":"Cano","year":"2001","journal-title":"Int. Arch. Occup. Environ. Health"},{"key":"10.1016\/j.leukres.2003.11.010_BIB23","unstructured":"Fritschi L, Johnson KC, Kliewer EV, Fry R, The Canadian Cancer Registries Epidemiology Research Group. Animal-related occupations and the risk of leukemia, myeloma, and non-Hodgkin\u2019s lymphoma in Canada. CCC 2002;13:563\u201371."},{"key":"10.1016\/j.leukres.2003.11.010_BIB24","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1001\/jama.275.17.1315","article-title":"Diet and risk of non-Hodgkin lymphoma in older women","volume":"275","author":"Chiu","year":"1996","journal-title":"J. Am. Med. Assoc."},{"key":"10.1016\/j.leukres.2003.11.010_BIB25","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1080\/01635589709514535","article-title":"Diet and risk of lymphoid neoplasms and soft tissue sarcomas","volume":"27","author":"Tavani","year":"1997","journal-title":"Nutr. Cancer"},{"key":"10.1016\/j.leukres.2003.11.010_BIB26","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1038\/bjc.1990.100","article-title":"Milk consumption and cancer incidence: a Norwegian prospective study","volume":"61","author":"Ursin","year":"1990","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.leukres.2003.11.010_BIB27","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1080\/01635588909514034","article-title":"Dietary factors and non-Hodgkin\u2019s lymphoma: a case\u2013control study in the northeastern part of Italy","volume":"12","author":"Franceschi","year":"1989","journal-title":"Nutr. Cancer"},{"key":"10.1016\/j.leukres.2003.11.010_BIB28","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1007\/BF01694756","article-title":"Dietary factors and non-Hodgkin\u2019s lymphoma in Nebraska (United States)","volume":"5","author":"Ward","year":"1994","journal-title":"Cancer Causes Control"},{"key":"10.1016\/j.leukres.2003.11.010_BIB29","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1038\/bjc.1988.118","article-title":"Multiple myeloma\u2014a case\u2013control study","volume":"57","author":"Cuzick","year":"1988","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.leukres.2003.11.010_BIB30","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1093\/oxfordjournals.aje.a010017","article-title":"Case\u2013control study of non-Hodgkin\u2019s lymphoma among women and heterosexual men in the San Francisco Bay Area, California","volume":"150","author":"Holly","year":"1999","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.leukres.2003.11.010_BIB31","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1097\/00008469-200002000-00008","article-title":"Medical history and risk of Hodgkin\u2019s and non-Hodgkin\u2019s lymphomas","volume":"9","author":"Tavani","year":"2000","journal-title":"Eur. J. Cancer Prev."},{"key":"10.1016\/j.leukres.2003.11.010_BIB32","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1136\/jech.54.6.431","article-title":"Haematopoietic cancer and medical history: a multicentre case control study","volume":"54","author":"Vineis","year":"2000","journal-title":"J. Epidemiol. Commun. Health"},{"key":"10.1016\/j.leukres.2003.11.010_BIB33","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1002\/ajim.10041","article-title":"Canadian male farm residents, pesticide safety handling practices, exposure to animals and non-Hodgkin\u2019s lymphoma (NHL)","volume":"2","author":"McDuffie","year":"2002","journal-title":"Am. J. Ind. Med."},{"key":"10.1016\/j.leukres.2003.11.010_BIB34","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1136\/thorax.55.6.449","article-title":"International patterns of tuberculosis and the prevalence of symptoms of asthma, rhinitis, and eczema","volume":"55","author":"Von Mutius","year":"2000","journal-title":"Thorax"},{"key":"10.1016\/j.leukres.2003.11.010_BIB35","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1128\/CMR.9.4.532","article-title":"Type 1 and type 2 cytokine dysregulation in human infectious, neoplastic, and inflammatory diseases","volume":"9","author":"Lucey","year":"1996","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.leukres.2003.11.010_BIB36","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1038\/35095579","article-title":"The germless theory of allergic disease: revisiting the hygiene hypothesis","volume":"1","author":"Wills-Karp","year":"2001","journal-title":"Nat. Rev. Immunol."},{"issue":"3","key":"10.1016\/j.leukres.2003.11.010_BIB37","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1001\/jama.283.3.343","article-title":"Measles history and atopic diseases: a population-based cross-sectional study","volume":"283","author":"Paunio","year":"2000","journal-title":"J. Am. Med. Assoc."},{"key":"10.1016\/j.leukres.2003.11.010_BIB38","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1086\/593682","article-title":"Bordetella pertussis respiratory infection in children is associated with preferential activation of type 1 T helper cells","volume":"175","author":"Ryan","year":"1997","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.leukres.2003.11.010_BIB39","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.4049\/jimmunol.170.3.1504","article-title":"Bordetella pertussis infection in 2-month-old infants promotes type 1 T cell responses","volume":"170","author":"Mascart","year":"2003","journal-title":"J. Immunol."},{"key":"10.1016\/j.leukres.2003.11.010_BIB40","first-page":"431","article-title":"BCG vaccination and the subsequent development of cancer in humans","volume":"66","author":"Kendrick","year":"1981","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1016\/j.leukres.2003.11.010_BIB41","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1093\/aje\/kwg145","article-title":"Population-based study of non-Hodgkin lymphoma, histology, and medical history among human immunodeficiency virus\u2014negative participants in San Francisco","volume":"158","author":"Holly","year":"2003","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.leukres.2003.11.010_BIB42","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1126\/science.275.5296.77","article-title":"The inverse association between tuberculin responses and atopic disorder","volume":"275","author":"Shirakawa","year":"1997","journal-title":"Science"},{"key":"10.1016\/j.leukres.2003.11.010_BIB43","doi-asserted-by":"crossref","first-page":"2740","DOI":"10.1002\/eji.1830231103","article-title":"Number of interleukin-4- and interferon-gamma-secreting human T cells reactive with tetanus toxoid and the mycobacterial antigen PPD or phytohemagglutinin: distinct response profiles depending on the type of antigen used for activation","volume":"23","author":"elGhazali","year":"1993","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.leukres.2003.11.010_BIB44","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1086\/515661","article-title":"Impaired tetanus-specific cellular and humoral responses following tetanus vaccination in human onchocerciasis: a possible role for interleukin-10","volume":"178","author":"Cooper","year":"1998","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.leukres.2003.11.010_BIB45","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0167-5699(97)01204-8","article-title":"Give us this day our daily germs","volume":"19","author":"Rook","year":"1998","journal-title":"Immunol. Today"},{"key":"10.1016\/j.leukres.2003.11.010_BIB46","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1038\/sj.bjc.6690395","article-title":"Association of childhood leukaemia with factors related to the immune system","volume":"80","author":"Sch\u00fcz","year":"1999","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.leukres.2003.11.010_BIB47","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1067\/mai.2002.126658","article-title":"Hay fever and asthma in relation to markers of infection in the United States","volume":"110","author":"Matricardi","year":"2002","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.leukres.2003.11.010_BIB48","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1136\/jech.54.12.907","article-title":"Delayed infection, family size and malignant lymphomas","volume":"54","author":"Vineis","year":"2000","journal-title":"J. Epidemiol. Commun. Health"},{"key":"10.1016\/j.leukres.2003.11.010_BIB49","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1034\/j.1399-3038.2003.00017.x","article-title":"Immune deviation and the hygiene hypothesis: a review of the epidemiological evidence","volume":"14","author":"Kemp","year":"2003","journal-title":"Pediatr. Allergy Immunol."}],"container-title":["Leukemia Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145212603004053?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145212603004053?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,3,30]],"date-time":"2020-03-30T14:17:27Z","timestamp":1585577847000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0145212603004053"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,7]]},"references-count":49,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2004,7]]}},"alternative-id":["S0145212603004053"],"URL":"https:\/\/doi.org\/10.1016\/j.leukres.2003.11.010","relation":{},"ISSN":["0145-2126"],"issn-type":[{"value":"0145-2126","type":"print"}],"subject":[],"published":{"date-parts":[[2004,7]]}}}