{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T08:14:53Z","timestamp":1788423293508,"version":"build-2803163510"},"reference-count":20,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2007,7,1]],"date-time":"2007-07-01T00:00:00Z","timestamp":1183248000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2007,7,1]],"date-time":"2007-07-01T00:00:00Z","timestamp":1183248000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2007,7,1]],"date-time":"2007-07-01T00:00:00Z","timestamp":1183248000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2007,7,1]],"date-time":"2007-07-01T00:00:00Z","timestamp":1183248000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2007,7,1]],"date-time":"2007-07-01T00:00:00Z","timestamp":1183248000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2007,7,1]],"date-time":"2007-07-01T00:00:00Z","timestamp":1183248000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2007,7,1]],"date-time":"2007-07-01T00:00:00Z","timestamp":1183248000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Leukemia Research"],"published-print":{"date-parts":[[2007,7]]},"DOI":"10.1016\/j.leukres.2006.11.014","type":"journal-article","created":{"date-parts":[[2007,1,4]],"date-time":"2007-01-04T19:02:16Z","timestamp":1167937336000},"page":"1009-1014","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Switch in X-inactivation in a JAK2 V617F-negative case of polycythemia vera with two acquired X-autosome translocations"],"prefix":"10.1016","volume":"31","author":[{"given":"Kalliopi N.","family":"Manola","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chryssa","family":"Stavropoulou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasileios N.","family":"Georgakakos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katerina","family":"Zoi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markos","family":"Fisfis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ilias","family":"Evmorfiadis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Zoi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriel E.","family":"Pantelias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katy","family":"Stefanoudaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Constantina","family":"Sambani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.leukres.2006.11.014_bib1","first-page":"51","article-title":"A polycythemia vera update: diagnosis, pathobiology, and treatment","author":"Pearson","year":"2000","journal-title":"Am Soc Haematol Program"},{"key":"10.1016\/j.leukres.2006.11.014_bib2","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.5858\/2006-130-1126-PV","article-title":"Polycythemia vera. New clinicopathologic perspectives","volume":"130","author":"Cao","year":"2006","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.leukres.2006.11.014_bib3","doi-asserted-by":"crossref","first-page":"4214","DOI":"10.1182\/blood-2005-08-3526","article-title":"Molecular basis of the diagnosis and treatment of polycythemia vera and essential thrombocythemia","volume":"105","author":"Schafer","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.leukres.2006.11.014_bib4","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1034\/j.1399-0004.1999.550511.x","article-title":"Characterization, phenotypic manifestations and X-inactivation pattern in 14 patients with X-autosome translocations","volume":"55","author":"Kalz-Fuller","year":"1999","journal-title":"Clin Genet"},{"key":"10.1016\/j.leukres.2006.11.014_bib5","doi-asserted-by":"crossref","first-page":"3145","DOI":"10.1093\/hmg\/11.25.3145","article-title":"Molecular and cytogenetic analysis of the spreading of X inactivation in X;autosome translocations","volume":"11","author":"Sharp","year":"2002","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.leukres.2006.11.014_bib6","doi-asserted-by":"crossref","first-page":"7706","DOI":"10.1073\/pnas.0602021103","article-title":"Attenuated spread of X-inactivation in an X-autosome translocation","volume":"103","author":"Popova","year":"2006","journal-title":"PNAS"},{"key":"10.1016\/j.leukres.2006.11.014_bib7","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/0165-4608(94)00283-H","article-title":"Characterization by chromosome painting of balanced and unbalanced X chromosome translocations in myelodysplastic syndromes","volume":"82","author":"Michaux","year":"1995","journal-title":"Cancer Genet Cytogenet"},{"key":"10.1016\/j.leukres.2006.11.014_bib8","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0165-4608(02)00764-1","article-title":"Translocation (X;20)(q13.1;q13.3) as a primary chromosomal finding in two patients with myelocytic disorders","volume":"141","author":"Gray","year":"2003","journal-title":"Cancer Genet Cytogenet"},{"key":"10.1016\/j.leukres.2006.11.014_bib9","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.cancergencyto.2004.08.029","article-title":"Translocation (X;20) involving the inactive X chromosome in a patient with myeloproliferative disorder","volume":"158","author":"O\u2019Reilly","year":"2005","journal-title":"Cancer Genet Cytogenet"},{"key":"10.1016\/j.leukres.2006.11.014_bib10","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.cancergencyto.2004.05.014","article-title":"Translocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders","volume":"157","author":"Reddy","year":"2005","journal-title":"Cancer Genet Cytogenet"},{"key":"10.1016\/j.leukres.2006.11.014_bib11","doi-asserted-by":"crossref","first-page":"2162","DOI":"10.1182\/blood-2005-03-1320","article-title":"Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disorders","volume":"106","author":"Jones","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.leukres.2006.11.014_bib12","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1016\/S0140-6736(05)71142-9","article-title":"Aquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders","volume":"365","author":"Baxter","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.leukres.2006.11.014_bib13","doi-asserted-by":"crossref","DOI":"10.1182\/blood-2005-12-013748","article-title":"Mutation of JAK2 in the myeloprilipherative disorders: timing, clonality sydies, cytogenetic associations and role in leukemic transformation","author":"Campbell","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.leukres.2006.11.014_bib14","doi-asserted-by":"crossref","first-page":"0","DOI":"10.1136\/jmg.35.11.932","article-title":"Severe phenotype resulting from an active ring X chromosome in a female with a complex karyotype: characterization and replication study","volume":"35","author":"Stavropoulou","year":"1998","journal-title":"J Med Genet"},{"key":"10.1016\/j.leukres.2006.11.014_bib15","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(\u2212Delta Delta C(T)) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.leukres.2006.11.014_bib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0165-4608(02)00863-4","article-title":"Deletion of chromosome 15 represents a rare but recurrent chromosomal abnormality in myelocytic malignancies","volume":"144","author":"Dierlamm","year":"2003","journal-title":"Cancer Genet Cytogenet"},{"key":"10.1016\/j.leukres.2006.11.014_bib17","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.cancergencyto.2003.09.016","article-title":"Deletion of chromosome arm 15q and hitherto unreported duplication of del(15q) in myeloid disorders","volume":"151","author":"Saunders","year":"2004","journal-title":"Cancer Genet Cytogenet"},{"key":"10.1016\/j.leukres.2006.11.014_bib18","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1006\/geno.2000.6128","article-title":"Characterization of a highly complex region in Xq13 and mapping of three isodicentric breakpoints associated with preleukemia","volume":"64","author":"McDonell","year":"2000","journal-title":"Genomics"},{"key":"10.1016\/j.leukres.2006.11.014_bib19","first-page":"1100","article-title":"An acquired translocation in JAK2 Val617 Phe-negative essential thrombocythemia associated with autosomal spread of X-inactivation","volume":"91","author":"Vassiliou","year":"2006","journal-title":"Haematologica"},{"key":"10.1016\/j.leukres.2006.11.014_bib20","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1056\/NEJMoa051113","article-title":"A gain-of-function mutation of JAK2 in myeloproliferative disorders","volume":"352","author":"Kralovics","year":"2005","journal-title":"N Engl J Med"}],"container-title":["Leukemia Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145212606004541?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145212606004541?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T07:44:55Z","timestamp":1788421495000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0145212606004541"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,7]]},"references-count":20,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2007,7]]}},"alternative-id":["S0145212606004541"],"URL":"https:\/\/doi.org\/10.1016\/j.leukres.2006.11.014","relation":{},"ISSN":["0145-2126"],"issn-type":[{"value":"0145-2126","type":"print"}],"subject":[],"published":{"date-parts":[[2007,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Switch in X-inactivation in a JAK2 V617F-negative case of polycythemia vera with two acquired X-autosome translocations","name":"articletitle","label":"Article Title"},{"value":"Leukemia Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.leukres.2006.11.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2006 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}