{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T22:14:57Z","timestamp":1768688097918,"version":"3.49.0"},"reference-count":31,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2011,3,1]],"date-time":"2011-03-01T00:00:00Z","timestamp":1298937600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Leukemia Research"],"published-print":{"date-parts":[[2011,3]]},"DOI":"10.1016\/j.leukres.2010.08.006","type":"journal-article","created":{"date-parts":[[2010,9,16]],"date-time":"2010-09-16T09:09:27Z","timestamp":1284628167000},"page":"334-339","source":"Crossref","is-referenced-by-count":21,"title":["Different prognostic factors for survival in acute and lymphomatous adult T-cell leukemia\/lymphoma"],"prefix":"10.1016","volume":"35","author":[{"given":"Brady","family":"Beltran","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pilar","family":"Qui\u00f1ones","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Domingo","family":"Morales","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esther","family":"Cotrina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge J.","family":"Castillo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.leukres.2010.08.006_bib0005","series-title":"WHO classification of tumours of haematopoietic and lymphoid tissues","article-title":"Adult T-cell leukaemia\/lymphoma","author":"Ohshima","year":"2008"},{"issue":"4","key":"10.1016\/j.leukres.2010.08.006_bib0010","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1080\/02841860802657235","article-title":"Adult T-cell leukemia\/lymphoma (ATL) presenting in the skin: clinical, histological and immunohistochemical features of 52 cases","volume":"48","author":"Bittencourt","year":"2009","journal-title":"Acta Oncol"},{"issue":"2","key":"10.1016\/j.leukres.2010.08.006_bib0015","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0268-960X(97)90015-1","article-title":"Human T-cell leukemia viruses: epidemiology, biology, and pathogenesis","volume":"11","author":"Ferreira","year":"1997","journal-title":"Blood Rev"},{"issue":"5","key":"10.1016\/j.leukres.2010.08.006_bib0020","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1097\/01.qai.0000221680.52563.d5","article-title":"High endemicity of human T-cell lymphotropic virus type 1 among pregnant women in Peru","volume":"42","author":"Alarcon","year":"2006","journal-title":"J Acquir Immune Defic Syndr"},{"issue":"2","key":"10.1016\/j.leukres.2010.08.006_bib0025","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/S1201-9712(03)90009-9","article-title":"Seroprevalence and risk factors for human T-cell lymphotropic virus (HTLV-I) infection among ethnically and geographically diverse Peruvian women","volume":"7","author":"Sanchez-Palacios","year":"2003","journal-title":"Int J Infect Dis"},{"issue":"5","key":"10.1016\/j.leukres.2010.08.006_bib0030","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1309\/2YGD1P0QCVCWBLDX","article-title":"Adult T-cell leukemia\/lymphoma in Bahia, Brazil: analysis of prognostic factors in a group of 70 patients","volume":"128","author":"Bittencourt","year":"2007","journal-title":"Am J Clin Pathol"},{"issue":"12","key":"10.1016\/j.leukres.2010.08.006_bib0035","doi-asserted-by":"crossref","first-page":"3054","DOI":"10.1002\/ijc.21688","article-title":"Clinical significance of serum Th1\u2013Th2- and regulatory T-cells-associated cytokines in adult T-cell leukemia\/lymphoma: high interleukin-5 and -10 levels are significant unfavorable prognostic factors","volume":"118","author":"Inagaki","year":"2006","journal-title":"Int J Cancer"},{"issue":"10 Pt 1","key":"10.1016\/j.leukres.2010.08.006_bib0040","first-page":"3625","article-title":"Clinical significance of CCR4 expression in adult T-cell leukemia\/lymphoma: its close association with skin involvement and unfavorable outcome","volume":"9","author":"Ishida","year":"2003","journal-title":"Clin Cancer Res"},{"issue":"4","key":"10.1016\/j.leukres.2010.08.006_bib0045","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1182\/blood.V98.4.1160","article-title":"Expression of functional lung resistance-related protein predicts poor outcome in adult T-cell leukemia","volume":"98","author":"Ohno","year":"2001","journal-title":"Blood"},{"issue":"5\u20136","key":"10.1016\/j.leukres.2010.08.006_bib0050","doi-asserted-by":"crossref","first-page":"415","DOI":"10.3109\/10428199609054779","article-title":"Clinical and biological significance of serum tumor markers in adult T-cell leukemia","volume":"22","author":"Sadamori","year":"1996","journal-title":"Leuk Lymphoma"},{"issue":"2","key":"10.1016\/j.leukres.2010.08.006_bib0055","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/1097-0142(19890115)63:2<289::AID-CNCR2820630214>3.0.CO;2-U","article-title":"Differences in prognostic factors between leukemia and lymphoma type of adult T-cell leukemia","volume":"63","author":"Shimamoto","year":"1989","journal-title":"Cancer"},{"issue":"7","key":"10.1016\/j.leukres.2010.08.006_bib0060","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1200\/JCO.1988.6.7.1088","article-title":"Major prognostic factors of adult patients with advanced T-cell lymphoma\/leukemia","volume":"6","author":"Shimoyama","year":"1988","journal-title":"J Clin Oncol"},{"issue":"4","key":"10.1016\/j.leukres.2010.08.006_bib0065","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1093\/annonc\/mdn696","article-title":"The International Prognostic Index predicts outcome in aggressive adult T-cell leukemia\/lymphoma: analysis of 126 patients from the International Peripheral T-Cell Lymphoma Project","volume":"20","author":"Suzumiya","year":"2009","journal-title":"Ann Oncol"},{"issue":"6","key":"10.1016\/j.leukres.2010.08.006_bib0070","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/j.leukres.2006.11.013","article-title":"Impact of visceral involvements and blood cell count abnormalities on survival in adult T-cell leukemia\/lymphoma (ATLL)","volume":"31","author":"Takasaki","year":"2007","journal-title":"Leuk Res"},{"issue":"2","key":"10.1016\/j.leukres.2010.08.006_bib0075","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.canlet.2005.03.039","article-title":"Impact of p53 aberration on the progression of adult T-cell leukemia\/lymphoma","volume":"234","author":"Tawara","year":"2006","journal-title":"Cancer Lett"},{"issue":"3","key":"10.1016\/j.leukres.2010.08.006_bib0080","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1200\/JCO.2008.18.2428","article-title":"Definition, prognostic factors, treatment, and response criteria of adult T-cell leukemia\/lymphoma: a proposal from an international consensus meeting","volume":"27","author":"Tsukasaki","year":"2009","journal-title":"J Clin Oncol"},{"issue":"7","key":"10.1016\/j.leukres.2010.08.006_bib0085","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/j.leukres.2006.10.017","article-title":"Clinical significance of a blood eosinophilia in adult T-cell leukemia\/lymphoma: a blood eosinophilia is a significant unfavorable prognostic factor","volume":"31","author":"Utsunomiya","year":"2007","journal-title":"Leuk Res"},{"issue":"5","key":"10.1016\/j.leukres.2010.08.006_bib0090","doi-asserted-by":"crossref","first-page":"1778","DOI":"10.1200\/JCO.1997.15.5.1778","article-title":"Deletions of p15 and\/or p16 genes as a poor-prognosis factor in adult T-cell leukemia","volume":"15","author":"Yamada","year":"1997","journal-title":"J Clin Oncol"},{"issue":"2\u20133","key":"10.1016\/j.leukres.2010.08.006_bib0095","first-page":"81","article-title":"Major prognostic factors of patients with adult T-cell leukemia\/lymphoma: a cooperative study. Lymphoma Study Group (1984\u20131987)","volume":"15","year":"1991","journal-title":"Leuk Res"},{"issue":"3","key":"10.1016\/j.leukres.2010.08.006_bib0100","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1111\/j.1365-2141.1991.tb08051.x","article-title":"Diagnostic criteria and classification of clinical subtypes of adult T-cell leukaemia-lymphoma. A report from the Lymphoma Study Group (1984\u20131987)","volume":"79","author":"Shimoyama","year":"1991","journal-title":"Br J Haematol"},{"issue":"14","key":"10.1016\/j.leukres.2010.08.006_bib0105","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1056\/NEJM199309303291402","article-title":"A predictive model for aggressive non-Hodgkin's lymphoma. The international non-Hodgkin's lymphoma prognostic factors project","volume":"329","year":"1993","journal-title":"N Engl J Med"},{"issue":"7","key":"10.1016\/j.leukres.2010.08.006_bib0110","doi-asserted-by":"crossref","first-page":"2474","DOI":"10.1182\/blood-2003-09-3080","article-title":"Peripheral T-cell lymphoma unspecified (PTCL-U): a new prognostic model from a retrospective multicentric clinical study","volume":"103","author":"Gallamini","year":"2004","journal-title":"Blood"},{"issue":"12","key":"10.1016\/j.leukres.2010.08.006_bib0115","doi-asserted-by":"crossref","first-page":"7415","DOI":"10.1073\/pnas.77.12.7415","article-title":"Detection and isolation of type C retrovirus particles from fresh and cultured lymphocytes of a patient with cutaneous T-cell lymphoma","volume":"77","author":"Poiesz","year":"1980","journal-title":"Proc Natl Acad Sci USA"},{"issue":"3","key":"10.1016\/j.leukres.2010.08.006_bib0120","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1182\/blood.V50.3.481.481","article-title":"Adult T-cell leukemia: clinical and hematologic features of 16 cases","volume":"50","author":"Uchiyama","year":"1977","journal-title":"Blood"},{"issue":"6","key":"10.1016\/j.leukres.2010.08.006_bib0125","doi-asserted-by":"crossref","first-page":"2031","DOI":"10.1073\/pnas.79.6.2031","article-title":"Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease","volume":"79","author":"Yoshida","year":"1982","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.leukres.2010.08.006_bib0130","series-title":"A nation-wide survey of HTLV-1-associated adult T-cell leukemia\/lymphoma (ATLL) in Japan","author":"Yamada","year":"2010"},{"issue":"11","key":"10.1016\/j.leukres.2010.08.006_bib0135","doi-asserted-by":"crossref","first-page":"4500","DOI":"10.1182\/blood-2005-09-3801","article-title":"Identification of subtype-specific genomic alterations in aggressive adult T-cell leukemia\/lymphoma","volume":"107","author":"Oshiro","year":"2006","journal-title":"Blood"},{"issue":"3\u20134","key":"10.1016\/j.leukres.2010.08.006_bib0140","doi-asserted-by":"crossref","first-page":"327","DOI":"10.3109\/10428199709051782","article-title":"Frequent hepatic involvement in adult T cell leukemia: comparison with non-Hodgkin's lymphoma","volume":"26","author":"Yamada","year":"1997","journal-title":"Leuk Lymphoma"},{"issue":"34","key":"10.1016\/j.leukres.2010.08.006_bib0145","doi-asserted-by":"crossref","first-page":"5458","DOI":"10.1200\/JCO.2007.11.9958","article-title":"VCAP-AMP-VECP compared with biweekly CHOP for adult T-cell leukemia\/lymphoma: Japan Clinical Oncology Group Study JCOG9801","volume":"25","author":"Tsukasaki","year":"2007","journal-title":"J Clin Oncol"},{"issue":"5","key":"10.1016\/j.leukres.2010.08.006_bib0150","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1038\/sj.leu.2403682","article-title":"Allogeneic hematopoietic stem cell transplantation provides sustained long-term survival for patients with adult T-cell leukemia\/lymphoma","volume":"19","author":"Fukushima","year":"2005","journal-title":"Leukemia"},{"issue":"1","key":"10.1016\/j.leukres.2010.08.006_bib0155","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1038\/sj.bmt.1702731","article-title":"Improved outcome of adult T cell leukemia\/lymphoma with allogeneic hematopoietic stem cell transplantation","volume":"27","author":"Utsunomiya","year":"2001","journal-title":"Bone Marrow Transplant"}],"container-title":["Leukemia Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145212610004078?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145212610004078?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,6,11]],"date-time":"2020-06-11T20:20:13Z","timestamp":1591906813000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0145212610004078"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3]]},"references-count":31,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011,3]]}},"alternative-id":["S0145212610004078"],"URL":"https:\/\/doi.org\/10.1016\/j.leukres.2010.08.006","relation":{},"ISSN":["0145-2126"],"issn-type":[{"value":"0145-2126","type":"print"}],"subject":[],"published":{"date-parts":[[2011,3]]}}}