{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T20:55:06Z","timestamp":1791752106436,"version":"4.3.4"},"reference-count":29,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Leukemia Research"],"published-print":{"date-parts":[[2012,3]]},"DOI":"10.1016\/j.leukres.2011.08.005","type":"journal-article","created":{"date-parts":[[2011,9,14]],"date-time":"2011-09-14T23:10:59Z","timestamp":1316041859000},"page":"275-280","source":"Crossref","is-referenced-by-count":18,"title":["Elevated Fas\/FasL system and endothelial cell microparticles are involved in endothelial damage in acute graft-versus-host disease: A clinical analysis"],"prefix":"10.1016","volume":"36","author":[{"given":"Qiuling","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huixin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linghui","family":"Xia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.leukres.2011.08.005_bib0005","doi-asserted-by":"crossref","first-page":"3373","DOI":"10.1182\/blood-2002-07-2231","article-title":"Nonmalignant late effects after allogeneic stem cell transplantation","volume":"101","author":"Socie","year":"2003","journal-title":"Blood"},{"issue":"1","key":"10.1016\/j.leukres.2011.08.005_bib0010","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1053\/j.seminhematol.2005.09.001","article-title":"Pathophysiology of graft-versus-host disease","volume":"43","author":"Ferrara","year":"2006","journal-title":"Semin Hematol"},{"issue":"2","key":"10.1016\/j.leukres.2011.08.005_bib0015","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.beha.2008.02.003","article-title":"Vascular endothelium and graft-versus-host disease","volume":"21","author":"Biedermann","year":"2008","journal-title":"Best Pract Res Clin Haematol"},{"issue":"2","key":"10.1016\/j.leukres.2011.08.005_bib0020","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.beha.2008.02.002","article-title":"Vascular endothelium as \u201cnovel\u201d target of graft-versus-host disease","volume":"21","author":"Tichelli","year":"2008","journal-title":"Best Pract Res Clin Haematol"},{"issue":"5","key":"10.1016\/j.leukres.2011.08.005_bib0025","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1038\/labinvest.3700541","article-title":"CD95 ligand-dependant endothelial cell death initiates oral mucosa damage in a murine model of acute graft versus host disease","volume":"87","author":"Deschaumes","year":"2007","journal-title":"Lab Invest"},{"issue":"3","key":"10.1016\/j.leukres.2011.08.005_bib0030","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/S0092-8674(00)81874-7","article-title":"Apoptosis by death factor","volume":"88","author":"Nagata","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.leukres.2011.08.005_bib0035","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1038\/nm0497-409","article-title":"Essential roles of the Fas ligand in the development of hepatitis","volume":"3","author":"Kondo","year":"1997","journal-title":"Nat Med"},{"issue":"9","key":"10.1016\/j.leukres.2011.08.005_bib0040","doi-asserted-by":"crossref","first-page":"2886","DOI":"10.1182\/blood.V97.9.2886","article-title":"Differential use of Fas ligand and perforin cytotoxic pathway by donor T-cells in graft-versus-host disease and graft-versus-leukemia effect","volume":"97","author":"Schmaltz","year":"2001","journal-title":"Blood"},{"issue":"4","key":"10.1016\/j.leukres.2011.08.005_bib0045","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.trsl.2007.06.003","article-title":"Pathophysiology of acute graft-vs-host disease: recent advances","volume":"150","author":"Sun","year":"2007","journal-title":"Transl Res"},{"issue":"3","key":"10.1016\/j.leukres.2011.08.005_bib0050","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1038\/sj.bmt.1703807","article-title":"Increased levels of immune transcript in patients with acute GVHD after allogenic stem cell transplantation","volume":"31","author":"Jaksch","year":"2003","journal-title":"Bone Marrow Transplant"},{"issue":"4","key":"10.1016\/j.leukres.2011.08.005_bib0055","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1097\/01.tp.0000229435.58898.c5","article-title":"Ex vivo soluble fas ligand treatment of donor cells to selectively reduce murine acute graft versus host disease","volume":"82","author":"Georgantas","year":"2006","journal-title":"Transplantation"},{"issue":"1","key":"10.1016\/j.leukres.2011.08.005_bib0060","doi-asserted-by":"crossref","first-page":"696","DOI":"10.4049\/jimmunol.0800561","article-title":"Selective reduction of graft-versus-host disease-mediating human T cells by ex vivo treatment with soluble Fas ligand","volume":"183","author":"Bohana-Kashtan","year":"2009","journal-title":"J Immunol"},{"issue":"3","key":"10.1016\/j.leukres.2011.08.005_bib0065","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1097\/01.moh.0000131441.10020.87","article-title":"Cellular microparticles, a disseminated storage pool of bioactive vascular effectors","volume":"11","author":"Morel","year":"2004","journal-title":"Curr Opin Hematol"},{"issue":"9","key":"10.1016\/j.leukres.2011.08.005_bib0070","doi-asserted-by":"crossref","first-page":"3603","DOI":"10.1182\/blood-2003-10-3479","article-title":"Circulating endothelial cells as a marker of endothelial damage in allogeneic hematopoietic stem cell transplantation","volume":"103","author":"Woywodt","year":"2004","journal-title":"Blood"},{"issue":"10","key":"10.1016\/j.leukres.2011.08.005_bib0075","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1097\/01.tp.0000209218.24916.ba","article-title":"Endothelial cell-derived microparticles in allogeneic hematopoietic stem cell recipients","volume":"81","author":"Pihusch","year":"2006","journal-title":"Transplantation"},{"issue":"6","key":"10.1016\/j.leukres.2011.08.005_bib0080","first-page":"825","article-title":"1994 consensus conference on acute GVHD grading","volume":"15","author":"Przepiorka","year":"1995","journal-title":"Bone Marrow Transplant"},{"issue":"4","key":"10.1016\/j.leukres.2011.08.005_bib0085","doi-asserted-by":"crossref","first-page":"210","DOI":"10.2302\/kjm.53.210","article-title":"New horizons in the analysis of circulating cell-derived microparticles","volume":"53","author":"Horstman","year":"2004","journal-title":"Keio J Med"},{"issue":"4","key":"10.1016\/j.leukres.2011.08.005_bib0090","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.vph.2006.11.005","article-title":"Endothelial injury in the initiation and progression of vascular disorders","volume":"46","author":"Tesfamariam","year":"2007","journal-title":"Vasc Pharmacol"},{"key":"10.1016\/j.leukres.2011.08.005_bib0095","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1038\/sj.bmt.1704258","article-title":"Combining altered levels of effector transcripts in circulating T cells with a marker of endothelial injury is specific for active graft-versus-host disease","volume":"32","author":"Biedermann","year":"2003","journal-title":"Bone Marrow Transpl"},{"issue":"9","key":"10.1016\/j.leukres.2011.08.005_bib0100","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1038\/sj.bmt.1703026","article-title":"Serum levels of soluble adhesion molecules in stem cell transplantation-related complications","volume":"27","author":"Matsuda","year":"2001","journal-title":"Bone Marrow Transpl"},{"issue":"5","key":"10.1016\/j.leukres.2011.08.005_bib0105","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1097\/01.shk.0000228791.10550.36","article-title":"Endothelium-derived microparticles induce endothelial dysfunction and acute lung injury","volume":"26","author":"Densmore","year":"2006","journal-title":"Shock"},{"issue":"3","key":"10.1016\/j.leukres.2011.08.005_bib0110","doi-asserted-by":"crossref","first-page":"H1106","DOI":"10.1152\/ajpheart.00265.2005","article-title":"Endothelial microparticles affect angiogenesis in vitro: role of oxidative stress","volume":"289","author":"Mezentsev","year":"2005","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"5","key":"10.1016\/j.leukres.2011.08.005_bib0115","doi-asserted-by":"crossref","first-page":"H1910","DOI":"10.1152\/ajpheart.01172.2003","article-title":"Endothelium-derived microparticles impair endothelial function in vitro","volume":"286","author":"Brodsky","year":"2004","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"7","key":"10.1016\/j.leukres.2011.08.005_bib0120","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/j.bbmt.2008.04.005","article-title":"Evaluation of angiopoietins and cell-derived microparticles after stem cell transplantation","volume":"14","author":"Nomura","year":"2008","journal-title":"Biol Blood Marrow Transplant"},{"issue":"1","key":"10.1016\/j.leukres.2011.08.005_bib0125","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1093\/molehr\/gah006","article-title":"First trimester trophoblast cells secrete Fas ligand which induces immune cell apoptosis","volume":"10","author":"Abrahams","year":"2004","journal-title":"Mol Hum Reprod"},{"issue":"5","key":"10.1016\/j.leukres.2011.08.005_bib0130","first-page":"1075","article-title":"Membrane vesicles shed by oligodendroglioma cells induce neuronal apoptosis","volume":"29","author":"D\u2019Agostino","year":"2006","journal-title":"Int J Oncol"},{"issue":"10","key":"10.1016\/j.leukres.2011.08.005_bib0135","doi-asserted-by":"crossref","first-page":"3862","DOI":"10.1182\/blood.V91.10.3862","article-title":"Biologically active Fas antigen and its cognate ligand are expressed on plasma membrane-derived extra cellular vesicles","volume":"91","author":"Albanese","year":"1998","journal-title":"Blood"},{"issue":"3","key":"10.1016\/j.leukres.2011.08.005_bib0140","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1111\/j.1365-2249.2007.03499.x","article-title":"Lipopolysaccharide and interferon-gamma enhance Fas-mediated cell death in mouse vascular endothelial cells via augmentation of Fas expression","volume":"150","author":"Koide","year":"2007","journal-title":"Clin Exp Immunol"},{"issue":"11","key":"10.1016\/j.leukres.2011.08.005_bib0145","doi-asserted-by":"crossref","first-page":"6964","DOI":"10.4049\/jimmunol.166.11.6964","article-title":"Fas ligand overexpression on allograft endothelium inhibits inflammatory cell infiltration and transplant-associated intimal hyperplasia","volume":"166","author":"Sata","year":"2001","journal-title":"J Immunol"}],"container-title":["Leukemia Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S014521261100405X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S014521261100405X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,6,23]],"date-time":"2020-06-23T21:13:17Z","timestamp":1592946797000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S014521261100405X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3]]},"references-count":29,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,3]]}},"alternative-id":["S014521261100405X"],"URL":"https:\/\/doi.org\/10.1016\/j.leukres.2011.08.005","relation":{},"ISSN":["0145-2126"],"issn-type":[{"value":"0145-2126","type":"print"}],"subject":[],"published":{"date-parts":[[2012,3]]}}}