{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T21:23:59Z","timestamp":1771881839692,"version":"3.50.1"},"reference-count":39,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2012,7,1]],"date-time":"2012-07-01T00:00:00Z","timestamp":1341100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Ministry of Sciences and Higher Education","award":["0059\/B\/P01\/2008\/35"],"award-info":[{"award-number":["0059\/B\/P01\/2008\/35"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Leukemia Research"],"published-print":{"date-parts":[[2012,7]]},"DOI":"10.1016\/j.leukres.2012.03.017","type":"journal-article","created":{"date-parts":[[2012,4,10]],"date-time":"2012-04-10T13:07:09Z","timestamp":1334063229000},"page":"846-851","source":"Crossref","is-referenced-by-count":1,"title":["CD105 and placental growth factor \u2013 Potent prognostic factors in childhood acute lymphoblastic leukaemia"],"prefix":"10.1016","volume":"36","author":[{"given":"Patrycja","family":"Sujka-Kordowska","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agnieszka","family":"Malinska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danuta","family":"Ostalska-Nowicka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maciej","family":"Zabel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michal","family":"Nowicki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.leukres.2012.03.017_bib0005","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0065-230X(08)60946-X","article-title":"Tumour angiogenesis","volume":"43","author":"Folkman","year":"1985","journal-title":"Adv Cancer Res"},{"key":"10.1016\/j.leukres.2012.03.017_bib0010","doi-asserted-by":"crossref","first-page":"2239","DOI":"10.1002\/(SICI)1097-0142(20000515)88:10<2239::AID-CNCR6>3.0.CO;2-V","article-title":"High expression of vascular endothelial growth factor is associated with liver metastasis and a poor prognosis for patients with ductal pancreatic adenocarcinoma","volume":"88","author":"Seo","year":"2000","journal-title":"Cancer"},{"key":"10.1016\/j.leukres.2012.03.017_bib0015","first-page":"5736","article-title":"Vascular endothelial growth factor is an autocrine survival factor for neuropilin-expressing breast carcinoma cells","volume":"61","author":"Bachelder","year":"2001","journal-title":"Cancer Res"},{"key":"10.1016\/j.leukres.2012.03.017_bib0020","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.ejim.2009.07.009","article-title":"The role of angiogenesis in solid tumours: an overview","volume":"20","author":"Makrilia","year":"2009","journal-title":"Eur J Intern Med"},{"key":"10.1016\/j.leukres.2012.03.017_bib0025","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1111\/j.1365-2141.1994.tb08304.x","article-title":"Bone marrow angiogenesis and progression in multiple myeloma","volume":"87","author":"Vacca","year":"1994","journal-title":"Br J Haematol"},{"key":"10.1016\/j.leukres.2012.03.017_bib0030","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1016\/S0022-3468(03)00385-3","article-title":"Significance of heparin-binding growth factor expression on cells of solid pediatric tumours","volume":"38","author":"Barthlen","year":"2003","journal-title":"J Pediatr Surg"},{"key":"10.1016\/j.leukres.2012.03.017_bib0035","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1097\/01.moh.0000168521.76120.7b","article-title":"Angiogenesis in lymphoproliferative disorders: a therapeutic target","volume":"12","author":"Aboudola","year":"2005","journal-title":"Curr Opin Hematol"},{"key":"10.1016\/j.leukres.2012.03.017_bib0040","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1002\/path.1900","article-title":"The expression of fibroblast growth factors and their receptors in Hodgkin's lymphoma","volume":"208","author":"Khnykin","year":"2006","journal-title":"J Pathol"},{"key":"10.1016\/j.leukres.2012.03.017_bib0045","first-page":"815","article-title":"Spectrum of tumour angiogenesis in the bone marrow of children with acute lymphoblastic leukaemia","volume":"150","author":"Perez-Atayde","year":"1997","journal-title":"Am J Pathol"},{"key":"10.1016\/j.leukres.2012.03.017_bib0050","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1046\/j.1365-2141.2002.03761.x","article-title":"Increased angiogenesis in bone marrow of children with acute lymphoblastic leukaemia has no prognostic significance","volume":"118","author":"Pul\u00e8","year":"2002","journal-title":"Br J Haematol"},{"key":"10.1016\/j.leukres.2012.03.017_bib0055","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1111\/j.1365-2141.2009.07796.x","article-title":"Vascular density in childhood acute lymphoblastic leukaemia correlates to biological factors and outcome","volume":"146","author":"Nor\u00e9n-Nystr\u00f6m","year":"2009","journal-title":"Br J Haematol"},{"key":"10.1016\/j.leukres.2012.03.017_bib0060","doi-asserted-by":"crossref","first-page":"171","DOI":"10.3349\/ymj.2007.48.2.171","article-title":"Clinical role of bone marrow angiogenesis in childhood acute lymphocytic leukaemia","volume":"48","author":"Lyu","year":"2007","journal-title":"Yonsei Med J"},{"key":"10.1016\/j.leukres.2012.03.017_bib0065","doi-asserted-by":"crossref","first-page":"83","DOI":"10.3109\/10428190109097679","article-title":"Clinical importance of serum vascular endothelial and basic fibroblast growth factors in children with acute lymphoblastic leukaemia","volume":"42","author":"Yetgin","year":"2001","journal-title":"Leuk Lymphoma"},{"key":"10.1016\/j.leukres.2012.03.017_bib0070","first-page":"147","article-title":"Expression of angiogenic factors in childhood B-cell precursor acute lymphoblastic leukaemia","volume":"17","author":"Stachel","year":"2007","journal-title":"Oncol Rep"},{"key":"10.1016\/j.leukres.2012.03.017_bib0075","first-page":"3381","article-title":"Vascular endothelial growth factor in newly diagnosed and recurrent childhood acute lymphoblastic leukaemia as measured by real-time quantitative polymerase chain reaction","volume":"7","author":"Koomagi","year":"2001","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.leukres.2012.03.017_bib0080","doi-asserted-by":"crossref","first-page":"6978","DOI":"10.1158\/1078-0432.CCR-06-1140","article-title":"Correlation between high vascular endothelial growth factor-A serum levels and treatment outcome in patients with standard-risk acute lymphoblastic leukaemia: a report from Children's Oncology Group Study CCG-1962","volume":"12","author":"Avramis","year":"2006","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.leukres.2012.03.017_bib0085","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1002\/pbc.20857","article-title":"Expression of vascular endothelial growth factor receptor 3 and Tie1 tyrosine kinase receptor on acute leukaemia cells","volume":"48","author":"Kivivuori","year":"2007","journal-title":"Pediatr Blood Cancer"},{"key":"10.1016\/j.leukres.2012.03.017_bib0090","series-title":"Multizentrische Therapiestudie ALL-BFM 90 zur Behandlung von Kindern und Jugendlichen mit akuter lymphoblastischer Leuk\u00e4mie (Non-B-ALL)","author":"Riehm","year":"1991"},{"key":"10.1016\/j.leukres.2012.03.017_bib0095","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1200\/JCO.1986.4.5.744","article-title":"Improved disease-free survival of children with acute lymphoblastic leukaemia at high risk for early relapse with New York regimen \u2013 a new intensive therapy protocol: a report from the Children's Cancer Study Group","volume":"4","author":"Steinherz","year":"1986","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.leukres.2012.03.017_bib0100","series-title":"ALL-REZ BFM 96 \u2013 studie zur Behandlung von Kindern mit Rezidivi einer akuten lymphoblastischen Leuk\u00e4mie","author":"Henze","year":"1997"},{"key":"10.1016\/j.leukres.2012.03.017_bib0105","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1038\/leu.2008.22","article-title":"Minimal residual disease (MRD) analysis in the non-MRD-based ALL IC-BFM 2002 protocol for childhood ALL: is it possible to avoid MRD testing","volume":"22","author":"Fronkova","year":"2008","journal-title":"Leukaemia"},{"key":"10.1016\/j.leukres.2012.03.017_bib0110","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1111\/j.1365-2559.2006.02465.x","article-title":"Vascular endothelial growth factor C \u2013 a potent risk factor in childhood acute lymphoblastic leukaemia: an immunocytochemical approach","volume":"49","author":"Nowicki","year":"2006","journal-title":"Histopathology"},{"key":"10.1016\/j.leukres.2012.03.017_bib0115","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1182\/blood.V95.1.309","article-title":"Evidence of increased angiogenesis in patients with acute myeloid leukaemia","volume":"95","author":"Hussong","year":"2000","journal-title":"Blood"},{"key":"10.1016\/j.leukres.2012.03.017_bib0120","doi-asserted-by":"crossref","first-page":"1369","DOI":"10.1038\/sj.leu.2402220","article-title":"Prognostic evaluation of the microvascular network in myelodysplastic syndromes","volume":"15","author":"Korkolopoulou","year":"2001","journal-title":"Leukaemia"},{"key":"10.1016\/j.leukres.2012.03.017_bib0125","doi-asserted-by":"crossref","first-page":"2240","DOI":"10.1182\/blood.V96.6.2240","article-title":"Angiogenesis in acute and chronic leukaemias and myelodysplastic syndromes","volume":"96","author":"Aguayo","year":"2000","journal-title":"Blood"},{"key":"10.1016\/j.leukres.2012.03.017_bib0130","doi-asserted-by":"crossref","first-page":"4303","DOI":"10.1182\/blood-2005-03-1010","article-title":"Angiogenic factors may have a different prognostic role in adult acute lymphoblastic leukaemia","volume":"106","author":"Faderl","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.leukres.2012.03.017_bib0135","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1002\/jcp.10200","article-title":"Differential levels of soluble endoglin [CD105] in myeloid malignancies","volume":"194","author":"Calabr\u00f2","year":"2003","journal-title":"J Cell Physiol"},{"key":"10.1016\/j.leukres.2012.03.017_bib0140","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1016\/j.leukres.2007.04.021","article-title":"Gene expression profiles that segregate patients with childhood acute lymphoblastic leukaemia: an independent validation study identifies that endoglin associates with patient outcome","volume":"31","author":"Catchpoole","year":"2007","journal-title":"Leuk Res"},{"key":"10.1016\/j.leukres.2012.03.017_bib0145","first-page":"537","article-title":"PGF isoforms, PLGF-1 and PGF-2 and the PGF receptor, neuropilin, in human breast cancer: prognostic significance","volume":"23","author":"Escudero-Esparza","year":"2010","journal-title":"Oncol Rep"},{"key":"10.1016\/j.leukres.2012.03.017_bib0150","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1182\/blood-2005-06-2530","article-title":"VEGFR-1 (FLT-1) activation modulates acute lymphoblastic leukaemia localization and survival within the bone marrow, determining the onset of extramedullary disease","volume":"107","author":"Fragoso","year":"2006","journal-title":"Blood"},{"key":"10.1016\/j.leukres.2012.03.017_bib0155","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1002\/hed.21335","article-title":"Expression of placenta growth factor: an independent factor for prediction of progression and prognosis of oral cancer","volume":"32","author":"Cheng","year":"2010","journal-title":"Head Neck"},{"key":"10.1016\/j.leukres.2012.03.017_bib0160","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1002\/ijc.25492","article-title":"Expression and prognostic significance of placental growth factor in hepatocellular carcinoma and peritumoural liver tissue","volume":"128","author":"Xu","year":"2011","journal-title":"Int J Cancer"},{"key":"10.1016\/j.leukres.2012.03.017_bib0165","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1038\/sj.bjc.6603966","article-title":"Marrow angiogenesis-associated factors as prognostic biomarkers in patients with acute myelogenous leukaemia","volume":"97","author":"Lee","year":"2007","journal-title":"Br J Cancer"},{"key":"10.1016\/j.leukres.2012.03.017_bib0170","first-page":"CR359","article-title":"Leukemia markers of peripheral blood vs bone marrow blasts Rusing flow cytometry","volume":"9","author":"Rezaei","year":"2003","journal-title":"Med Sci Monit"},{"key":"10.1016\/j.leukres.2012.03.017_bib0175","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/S0301-472X(01)00766-4","article-title":"Heparanase expression in human leukemias is restricted to acute myeloid leukemias","volume":"30","author":"Bitan","year":"2002","journal-title":"Exp Hematol"},{"key":"10.1016\/j.leukres.2012.03.017_bib0180","first-page":"1824","article-title":"Identification of B94 (TNFAIP2) as a potential retinoic acid target gene in acute promyelocytic leukemia","volume":"60","author":"Rusiniak","year":"2000","journal-title":"Cancer Res"},{"key":"10.1016\/j.leukres.2012.03.017_bib0185","first-page":"1090","article-title":"Behavior of activities of thymidine metabolizing enzymes in human leukemia\u2013lymphoma cells","volume":"49","author":"Shiotani","year":"1989","journal-title":"Cancer Res"},{"key":"10.1016\/j.leukres.2012.03.017_bib0190","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/S0092-8674(00)81433-6","article-title":"Cyclooxygenase regulates angiogenesis induced by colon cancer cells","volume":"93","author":"Tsujii","year":"1998","journal-title":"Cell"},{"key":"10.1016\/j.leukres.2012.03.017_bib0195","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1016\/j.leukres.2007.01.015","article-title":"Expression of matrix metalloproteinase (MMP) and tissue inhibitor of MMP (TIMP) genes in blasts of infant acute lymphoblastic leukemia with organ involvement","volume":"31","author":"Suminoe","year":"2007","journal-title":"Leuk Res"}],"container-title":["Leukemia Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145212612001403?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145212612001403?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,7,5]],"date-time":"2020-07-05T17:49:21Z","timestamp":1593971361000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0145212612001403"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7]]},"references-count":39,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2012,7]]}},"alternative-id":["S0145212612001403"],"URL":"https:\/\/doi.org\/10.1016\/j.leukres.2012.03.017","relation":{},"ISSN":["0145-2126"],"issn-type":[{"value":"0145-2126","type":"print"}],"subject":[],"published":{"date-parts":[[2012,7]]}}}