{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T23:47:33Z","timestamp":1776124053907,"version":"3.50.1"},"reference-count":24,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100002655","name":"Terry Fox Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002655","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Leukemia Research"],"published-print":{"date-parts":[[2013,10]]},"DOI":"10.1016\/j.leukres.2013.07.020","type":"journal-article","created":{"date-parts":[[2013,8,12]],"date-time":"2013-08-12T16:31:14Z","timestamp":1376325074000},"page":"1216-1221","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":36,"title":["Pregnancies in patients with chronic myeloid leukemia treated with tyrosine kinase inhibitor"],"prefix":"10.1016","volume":"37","author":[{"given":"Li","family":"Zhou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian-Hua","family":"You","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun-Min","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhi-Xiang","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ai-Hua","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.leukres.2013.07.020_bib0005","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/1756-9966-29-20","article-title":"Summary of 615 patients of chronic myeloid leukemia in Shanghai from 2001 to 2006","volume":"29","author":"Wang","year":"2010","journal-title":"J Exp Clin Cancer Res"},{"key":"10.1016\/j.leukres.2013.07.020_bib0010","unstructured":"Novartis Pharmaceuticals Corporation [Internet]. Available from: www.phama.us.novartis.com\/product\/pi\/pdf\/gleevec_tabs.pdf."},{"key":"10.1016\/j.leukres.2013.07.020_bib0015","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1111\/j.1365-2605.2007.00755.x","article-title":"Inhibition of tyrosine kinases PDGFR and c-KIT by imatinib mesylate interferes with postnatal testicular development in the rat","volume":"30","author":"Nurmio","year":"2007","journal-title":"Int J Androl"},{"key":"10.1016\/j.leukres.2013.07.020_bib0020","doi-asserted-by":"crossref","first-page":"6226","DOI":"10.1210\/en.2008-0349","article-title":"Platelet-derived growth factor receptor beta-subtype regulates proliferation and migration of gonocytes","volume":"149","author":"Basciani","year":"2008","journal-title":"Endocrinology"},{"key":"10.1016\/j.leukres.2013.07.020_bib0025","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/j.reprotox.2008.03.004","article-title":"Adult reproductive functions after early postnatal inhibition by imatinib of the two receptor tyrosine kinases, c-kit and PDGFR, in the rat testis","volume":"25","author":"Nurmio","year":"2008","journal-title":"Reprod Toxicol"},{"key":"10.1016\/j.leukres.2013.07.020_bib0030","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1053\/shem.2003.50038","article-title":"Imatinib treatment: Specific issues related to safety, fertility and pregnancy","volume":"40","author":"Hensley","year":"2003","journal-title":"Semin Hematol"},{"key":"10.1016\/j.leukres.2013.07.020_bib0035","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1200\/JCO.2005.04.6557","article-title":"Pregnancy among patients with chronic myeloid leukaemia treated with imatinib","volume":"24","author":"Ault","year":"2006","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.leukres.2013.07.020_bib0040","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.leukres.2007.07.022","article-title":"Male patients with chronic myeloid leukemia treated with imatinib involved in healthy pregnancies: report of five cases","volume":"32","author":"Breccia","year":"2008","journal-title":"Leuk Res"},{"key":"10.1016\/j.leukres.2013.07.020_bib0045","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1111\/j.1365-2141.2007.06542.x","article-title":"Successful pregnancies involving men with chronic myeloid leukaemia on imatinib therapy","volume":"137","author":"Ramasamy","year":"2007","journal-title":"Br J Haematol"},{"key":"10.1016\/j.leukres.2013.07.020_bib0050","first-page":"168","article-title":"Conception of healthy children under imatinib treatment in two men affected by chronic myeloid leukaemia","volume":"94","author":"Pacilli","year":"2009","journal-title":"Hematologica"},{"issue":"5","key":"10.1016\/j.leukres.2013.07.020_bib0055","doi-asserted-by":"crossref","first-page":"734","DOI":"10.3109\/0284186X.2011.577562","article-title":"Fatherhood during imatinib","volume":"50","author":"Shash","year":"2011","journal-title":"Acta Oncol"},{"issue":"3","key":"10.1016\/j.leukres.2013.07.020_bib0060","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.leukres.2011.09.025","article-title":"Imatinib mesylate at therapeutic doses has no impact on folliculogenesis or spermatogenesis in a leukaemic mouse model","volume":"36","author":"Schultheis","year":"2012","journal-title":"Leuk Res"},{"key":"10.1016\/j.leukres.2013.07.020_bib0065","doi-asserted-by":"crossref","first-page":"2134","DOI":"10.1056\/NEJM200411113512024","article-title":"Oligospermia in a patient receiving imatinib therapy for the hypereosinophilic syndrome","volume":"351","author":"Seshadri","year":"2004","journal-title":"New Engl J Med"},{"issue":"3","key":"10.1016\/j.leukres.2013.07.020_bib0070","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1016\/j.fertnstert.2010.08.060","article-title":"Severe oligozoospermia in a young man with chronic myeloid leukemia on long term treatment with imatinib started before puberty","volume":"95","author":"Mariani","year":"2011","journal-title":"Fertil Steril"},{"key":"10.1016\/j.leukres.2013.07.020_bib0075","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/j.cardiores.2006.05.019","article-title":"Platelet-derived growth factor B retention is essential for development of normal structure and function of conduit vessels and capillaries","volume":"71","author":"Nystr\u00f6m","year":"2006","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.leukres.2013.07.020_bib0080","doi-asserted-by":"crossref","first-page":"5505","DOI":"10.1182\/blood-2007-10-114900","article-title":"The effects of imatinib on pregnancy outcome","volume":"111","author":"Pye","year":"2008","journal-title":"Blood"},{"issue":"2","key":"10.1016\/j.leukres.2013.07.020_bib0085","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1007\/s00404-008-0861-7","article-title":"Imatinib use during pregnancy and breast feeding: a case report and review of the literature","volume":"280","author":"Ali","year":"2009","journal-title":"Arch Gynecol Obstet"},{"issue":"4","key":"10.1016\/j.leukres.2013.07.020_bib0090","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1093\/jjco\/hyh038","article-title":"Successful pregnancy and delivery in a patient with chronic myelogenous leukemia, and management of CML with leukapheresis during pregnancy: a case report and review of the literature","volume":"34","author":"Ali","year":"2004","journal-title":"Jpn J Clin Oncol"},{"issue":"4","key":"10.1016\/j.leukres.2013.07.020_bib0095","doi-asserted-by":"crossref","first-page":"324","DOI":"10.3816\/CLM.2009.n.064","article-title":"Successful completion of pregnancy in a patient with chronic myeloid leukemia without active intervention: a case report and review of the literature","volume":"9","author":"Cole","year":"2009","journal-title":"Clin Lymphoma Myeloma"},{"key":"10.1016\/j.leukres.2013.07.020_bib0100","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.ejca.2005.10.014","article-title":"Cancer and pregnancy: poena magna, not anymore","volume":"42","author":"Pentheroudakis","year":"2006","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.leukres.2013.07.020_bib0105","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/S1470-2045(04)01466-4","article-title":"Use of chemotherapy during human pregnancy","volume":"5","author":"Cardonick","year":"2004","journal-title":"Lancet Oncol"},{"issue":"1","key":"10.1016\/j.leukres.2013.07.020_bib0110","doi-asserted-by":"crossref","first-page":"121","DOI":"10.5507\/bp.2008.019","article-title":"Successful childbirth in a patient with chronic myelogenous leukemia treated with imatinib mesylate during early pregnancy","volume":"152","author":"Skoumalova","year":"2008","journal-title":"Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub"},{"issue":"1","key":"10.1016\/j.leukres.2013.07.020_bib0115","first-page":"6","article-title":"Pregnancy outcome among patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors","volume":"33","author":"Jiang","year":"2012","journal-title":"Zhonghua Xue Ye Xue Za Zhi"},{"key":"10.1016\/j.leukres.2013.07.020_bib0120","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1038\/sj.jp.7211665","article-title":"Imatinib mesylate and metabolite concentrations in maternal blood, umbilical cord, placenta and breast milk","volume":"27","author":"Russell","year":"2007","journal-title":"J Perinatol"}],"container-title":["Leukemia Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145212613002476?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145212613002476?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T00:58:18Z","timestamp":1758934698000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0145212613002476"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10]]},"references-count":24,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["S0145212613002476"],"URL":"https:\/\/doi.org\/10.1016\/j.leukres.2013.07.020","relation":{},"ISSN":["0145-2126"],"issn-type":[{"value":"0145-2126","type":"print"}],"subject":[],"published":{"date-parts":[[2013,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pregnancies in patients with chronic myeloid leukemia treated with tyrosine kinase inhibitor","name":"articletitle","label":"Article Title"},{"value":"Leukemia Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.leukres.2013.07.020","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}