{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,2]],"date-time":"2024-08-02T09:53:05Z","timestamp":1722592385784},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001411","name":"Indian Council of Medical Research, Government of India","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100001411","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Terry-Fox Foundation through Institutional Review Board, Tata Memorial Centre, Mumbai"},{"name":"Genotypic Technology Pvt. Ltd., Bengaluru, India,"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","lrjournal.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Leukemia Research"],"published-print":{"date-parts":[[2016,6]]},"DOI":"10.1016\/j.leukres.2016.03.002","type":"journal-article","created":{"date-parts":[[2016,4,3]],"date-time":"2016-04-03T12:53:12Z","timestamp":1459687992000},"page":"33-39","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Risk stratification of T-cell Acute Lymphoblastic Leukemia patients based on gene expression, mutations and copy number variation"],"prefix":"10.1016","volume":"45","author":[{"given":"Gauri","family":"Mirji","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaydeep","family":"Bhat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jyoti","family":"Kode","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shripad","family":"Banavali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manju","family":"Sengar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prashant","family":"Khadke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Osama","family":"Sait","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shubhada","family":"Chiplunkar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.leukres.2016.03.002_bib0005","doi-asserted-by":"crossref","first-page":"3398","DOI":"10.1172\/JCI61269","article-title":"The molecular basis of T cell acute lymphoblastic leukemia","volume":"122","author":"Van Vlierberghe","year":"2012","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.leukres.2016.03.002_bib0010","doi-asserted-by":"crossref","first-page":"310","DOI":"10.3109\/10428194.2012.710330","article-title":"Gene expression pattern contributing to prognostic factors in childhood acute lymphoblastic leukemia","volume":"54","author":"Silveira","year":"2013","journal-title":"Leuk. Lymphoma"},{"key":"10.1016\/j.leukres.2016.03.002_bib0015","first-page":"735","article-title":"Biology and treatment of childhood T-lineage acute lymphoblastic leukemia","volume":"91","author":"Uckun","year":"1998","journal-title":"Blood"},{"key":"10.1016\/j.leukres.2016.03.002_bib0020","doi-asserted-by":"crossref","first-page":"331","DOI":"10.3109\/10428190009148854","article-title":"T-cell receptor gamma and delta gene rearrangements in T-cell acute lymphoblastic leukemia in Indian patients","volume":"36","author":"Kode","year":"2000","journal-title":"Leuk. Lymphoma"},{"key":"10.1016\/j.leukres.2016.03.002_bib0025","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1080\/1042819031000139657","article-title":"Clonal T-cell receptor gamma and delta gene rearrangements in T-cell acute lymphoblastic leukemia at diagnosis: predictor of prognosis and response to chemotherapy","volume":"45","author":"Kode","year":"2004","journal-title":"Leuk. Lymphoma"},{"key":"10.1016\/j.leukres.2016.03.002_bib0030","first-page":"769","article-title":"T-cell receptor gamma and delta junctional gene rearrangements as diagnostic and prognostic biomarker for T-cell acute lymphoblastic leukemia","volume":"47","author":"Kode","year":"2006","journal-title":"Leuk. Lymphoma"},{"key":"10.1016\/j.leukres.2016.03.002_bib0035","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1097\/MOH.0b013e3283623c61","article-title":"Early T-cell precursor acute lymphoblastic leukaemia","volume":"20","author":"Haydu","year":"2013","journal-title":"Curr. Opin. Hematol."},{"key":"10.1016\/j.leukres.2016.03.002_bib0040","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1182\/blood-2014-03-562918","article-title":"A novel integrated cytogenetic and genomic classification refines risk stratification in pediatric acute lymphoblastic leukemia","volume":"124","author":"Moorman","year":"2014","journal-title":"Blood"},{"key":"10.1016\/j.leukres.2016.03.002_bib0045","doi-asserted-by":"crossref","first-page":"e157","DOI":"10.1038\/bcj.2013.54","article-title":"ASXL1, TP53 and IKZF3 mutations are present in the chronic phase and blast crisis of chronic myeloid leukemia","volume":"3","author":"Menezes","year":"2013","journal-title":"Blood Cancer J."},{"key":"10.1016\/j.leukres.2016.03.002_bib0050","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta C(T)) Method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.leukres.2016.03.002_bib0055","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1038\/nm1524","article-title":"Targeting the NF-kappaB signaling pathway in Notch1-induced T-cell leukemia","volume":"13","author":"Vilimas","year":"2007","journal-title":"Nat. Med."},{"key":"10.1016\/j.leukres.2016.03.002_bib0060","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1016\/S1074-7613(00)00067-4","article-title":"activation by the pre-T cell receptor serves as a selective survival signal in T lymphocyte development","volume":"13","author":"Voll","year":"2000","journal-title":"Immunity"},{"key":"10.1016\/j.leukres.2016.03.002_bib0065","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0959-437X(96)90009-X","article-title":"New members of the Bcl-2 family and their protein partners","volume":"6","author":"Farrow","year":"1996","journal-title":"Curr. Opin. Genet. Dev."},{"key":"10.1016\/j.leukres.2016.03.002_bib0070","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1590\/S1415-47572013005000003","article-title":"Enhanced levels of the apoptotic BAX\/BCL-2 ratio in children with acute lymphoblastic leukemia and high-risk features","volume":"36","author":"Kaparou","year":"2013","journal-title":"Genet. Mol. Biol."},{"key":"10.1016\/j.leukres.2016.03.002_bib0075","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1046\/j.1365-2141.2000.02315.x","article-title":"High bax expression is a good prognostic indicator in acute myeloid leukaemia","volume":"111","author":"Ong","year":"2000","journal-title":"Br. J. Haematol."},{"key":"10.1016\/j.leukres.2016.03.002_bib0080","first-page":"903","article-title":"Fas signaling and blockade of Bcr-Abl kinase induce apoptotic Hrk protein via DREAM inhibition in human leukemia cells","volume":"87","author":"Sanz","year":"2002","journal-title":"Haematologica"},{"key":"10.1016\/j.leukres.2016.03.002_bib0085","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/978-1-4615-4811-9_27","article-title":"CD95 (FAS\/APO-1) antigen is a new prognostic marker of blast cells of acute lymphoblastic leukaemia patients","volume":"457","author":"Baryshnikov","year":"1999","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.leukres.2016.03.002_bib0090","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1126\/science.1102160","article-title":"Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia","volume":"306","author":"Weng","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.leukres.2016.03.002_bib0095","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1182\/blood-2013-03-491092","article-title":"Prognostic relevance of integrated genetic profiling in adult T-cell acute lymphoblastic leukemia","volume":"122","author":"Van Vlierberghe","year":"2013","journal-title":"Blood"},{"key":"10.1016\/j.leukres.2016.03.002_bib0100","doi-asserted-by":"crossref","first-page":"3043","DOI":"10.1158\/1078-0432.CCR-05-2832","article-title":"NOTCH1 mutations in T-cell acute lymphoblastic leukemia: prognostic significance and implication in multifactorial leukemogenesis","volume":"12","author":"Zhu","year":"2006","journal-title":"Clin. Cancer Res.: Off. J. Am. Assoc. Cancer Res."},{"key":"10.1016\/j.leukres.2016.03.002_bib0105","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1002\/pbc.24803","article-title":"Prognostic implications of mutations in NOTCH1 and FBXW7 in childhood T-ALL treated according to the NOPHO ALL-1992 and ALL-2000 protocols","volume":"61","author":"Fogelstrand","year":"2014","journal-title":"Pediatric Blood Cancer"},{"key":"10.1016\/j.leukres.2016.03.002_bib0110","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1182\/blood-2014-02-557819","article-title":"Identification of cereblon-binding proteins and relationship with response and survival after IMiDs in multiple myeloma","volume":"124","author":"Zhu","year":"2014","journal-title":"Blood"},{"key":"10.1016\/j.leukres.2016.03.002_bib0115","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1002\/pbc.22996","article-title":"Improving outcomes for high-risk ALL: translating new discoveries into clinical care","volume":"56","author":"Hunger","year":"2011","journal-title":"Pediatric Blood Cancer"},{"key":"10.1016\/j.leukres.2016.03.002_bib0120","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.ccell.2015.07.016","article-title":"Efficacy of retinoids in IKZF1-mutated BCR-ABL1 acute lymphoblastic leukemia","volume":"28","author":"Churchman","year":"2015","journal-title":"Cancer Cell"},{"key":"10.1016\/j.leukres.2016.03.002_bib0125","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1038\/ng.2532","article-title":"The genomic landscape of hypodiploid acute lymphoblastic leukemia","volume":"45","author":"Holmfeldt","year":"2013","journal-title":"Nat. Genet."},{"key":"10.1016\/j.leukres.2016.03.002_bib0130","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.3109\/10428194.2012.733878","article-title":"BRAF V600E mutation in adult acute lymphoblastic leukemia","volume":"54","author":"Alonso","year":"2013","journal-title":"Leuk. Lymphoma"},{"key":"10.1016\/j.leukres.2016.03.002_bib0135","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.1038\/leu.2008.14","article-title":"BRAF mutations are very rare in B- and T-cell pediatric acute lymphoblastic leukemias","volume":"22","author":"Davidsson","year":"2008","journal-title":"Leukemia"},{"key":"10.1016\/j.leukres.2016.03.002_bib0140","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1038\/sj.leu.2403589","article-title":"Mutations in the BRAF and N-ras genes in childhood acute lymphoblastic leukaemia","volume":"19","author":"Gustafsson","year":"2005","journal-title":"Leukemia"},{"key":"10.1016\/j.leukres.2016.03.002_bib0145","first-page":"881","article-title":"The prognostic significance of CDKN2A, CDKN2B and MTAP inactivation in B-lineage acute lymphoblastic leukemia of childhood Results of the EORTC studies 58881 and 58951","volume":"91","author":"Mirebeau","year":"2006","journal-title":"Haematologica"},{"key":"10.1016\/j.leukres.2016.03.002_bib0150","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1016\/j.leukres.2008.01.014","article-title":"CDKN2A deletions in acute lymphoblastic leukemia of adolescents and young adults: an array CGH study","volume":"32","author":"Usvasalo","year":"2008","journal-title":"Leuk. Res."},{"key":"10.1016\/j.leukres.2016.03.002_bib0155","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1158\/1078-0432.CCR-13-2175","article-title":"Inactivation of the CDKN2A tumor-suppressor gene by deletion or methylation is common at diagnosis in follicular lymphoma and associated with poor clinical outcome","volume":"20","author":"Alhejaily","year":"2014","journal-title":"Clin. Cancer Res.: Off. J. Am. Assoc. Cancer Res."},{"key":"10.1016\/j.leukres.2016.03.002_bib0160","doi-asserted-by":"crossref","first-page":"7413","DOI":"10.1158\/1078-0432.CCR-11-1227","article-title":"CDKN2A\/B alterations impair prognosis in adult BCR-ABL1-positive acute lymphoblastic leukemia patients","volume":"17","author":"Iacobucci","year":"2011","journal-title":"Clin. Cancer Res.: Off. J. Am. Assoc. Cancer Res."},{"key":"10.1016\/j.leukres.2016.03.002_bib0165","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.cancergencyto.2009.06.013","article-title":"Homozygous deletion of CDKN2A (p16, p14) and CDKN2B (p15) genes is a poor prognostic factor in adult but not in childhood B-lineage acute lymphoblastic leukemia: a comparative deletion and hypermethylation study","volume":"195","author":"Kim","year":"2009","journal-title":"Cancer Genet. Cytogenet."}],"container-title":["Leukemia Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145212616300297?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145212616300297?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,13]],"date-time":"2018-09-13T18:59:45Z","timestamp":1536865185000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0145212616300297"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6]]},"references-count":33,"alternative-id":["S0145212616300297"],"URL":"https:\/\/doi.org\/10.1016\/j.leukres.2016.03.002","relation":{},"ISSN":["0145-2126"],"issn-type":[{"value":"0145-2126","type":"print"}],"subject":[],"published":{"date-parts":[[2016,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Risk stratification of T-cell Acute Lymphoblastic Leukemia patients based on gene expression, mutations and copy number variation","name":"articletitle","label":"Article Title"},{"value":"Leukemia Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.leukres.2016.03.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}