{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T05:25:29Z","timestamp":1786685129068,"version":"build-2736575974"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,12,1]],"date-time":"2019-12-01T00:00:00Z","timestamp":1575158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"Thai Society of Hematology"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Leukemia Research"],"published-print":{"date-parts":[[2019,12]]},"DOI":"10.1016\/j.leukres.2019.106235","type":"journal-article","created":{"date-parts":[[2019,10,15]],"date-time":"2019-10-15T11:37:54Z","timestamp":1571139474000},"page":"106235","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Better survivals in adolescent and Young adults, compared to adults with acute lymphoblastic leukemia \u2013 A multicenter prospective registry in Thai population"],"prefix":"10.1016","volume":"87","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1451-7636","authenticated-orcid":false,"given":"Wasithep","family":"Limvorapitak","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1262-2005","authenticated-orcid":false,"given":"Weerapat","family":"Owattanapanich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eakkapol","family":"Utchariyaprasit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pimjai","family":"Niparuck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teeraya","family":"Puavilai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2381-9292","authenticated-orcid":false,"given":"Adisak","family":"Tantiworawit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thanawat","family":"Rattanathammethee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Supawee","family":"Saengboon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chantarapa","family":"Sriswasdi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakrawadee","family":"Julamanee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3900-460X","authenticated-orcid":false,"given":"Piroon","family":"Saelue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chantana","family":"Polprasert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kitsada","family":"Wudhikarn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chinadol","family":"Wanitpongpun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kannadit","family":"Prayongratana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.leukres.2019.106235_bib0005","series-title":"WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues","first-page":"167","article-title":"Precursor lymphoid neoplasms","author":"Borowitz","year":"2008"},{"issue":"20","key":"10.1016\/j.leukres.2019.106235_bib0010","doi-asserted-by":"crossref","first-page":"2391","DOI":"10.1182\/blood-2016-03-643544","article-title":"The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia","volume":"127","author":"Arber","year":"2016","journal-title":"Blood"},{"key":"10.1016\/j.leukres.2019.106235_bib0015","series-title":"SEER Cancer Statistics Review, 1975-2015","author":"Noone","year":"2018"},{"issue":"3","key":"10.1016\/j.leukres.2019.106235_bib0020","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1002\/ajh.24987","article-title":"Outcome of patients with relapsed\/refractory acute lymphoblastic leukemia after blinatumomab failure: No change in the level of CD19 expression","volume":"93","author":"Jabbour","year":"2018","journal-title":"Am. J. Hematol."},{"issue":"9","key":"10.1016\/j.leukres.2019.106235_bib0025","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1056\/NEJMoa1609783","article-title":"Blinatumomab versus chemotherapy for advanced acute lymphoblastic leukemia","volume":"376","author":"Kantarjian","year":"2017","journal-title":"N. Engl. J. Med."},{"issue":"12","key":"10.1016\/j.leukres.2019.106235_bib0030","doi-asserted-by":"crossref","first-page":"2788","DOI":"10.1002\/cncr.20668","article-title":"Long-term follow-up results of hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone (Hyper-CVAD), a dose-intensive regimen, in adult acute lymphocytic leukemia","volume":"101","author":"Kantarjian","year":"2004","journal-title":"Cancer"},{"issue":"7","key":"10.1016\/j.leukres.2019.106235_bib0035","first-page":"809","article-title":"Allogeneic stem cell transplantation in acute lymphoblastic leukemia and non-Hodgkin\u2019s lymphoma for patients <or=50 years old in first complete remission: results of the EORTC ALL-3 trial","volume":"89","author":"Labar","year":"2004","journal-title":"Haematologica"},{"issue":"23","key":"10.1016\/j.leukres.2019.106235_bib0040","doi-asserted-by":"crossref","first-page":"4158","DOI":"10.1002\/cncr.29646","article-title":"Long-term follow-up of a phase 2 study of chemotherapy plus dasatinib for the initial treatment of patients with Philadelphia chromosome-positive acute lymphoblastic leukemia","volume":"121","author":"Ravandi","year":"2015","journal-title":"Cancer"},{"issue":"4","key":"10.1016\/j.leukres.2019.106235_bib0045","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1111\/j.1365-2141.2010.08246.x","article-title":"Prognostic factors in adult acute lymphoblastic leukaemia","volume":"150","author":"Rowe","year":"2010","journal-title":"Br. J. Haematol."},{"issue":"12","key":"10.1016\/j.leukres.2019.106235_bib0050","doi-asserted-by":"crossref","first-page":"3760","DOI":"10.1182\/blood-2005-04-1623","article-title":"Induction therapy for adults with acute lymphoblastic leukemia: results of more than 1500 patients from the international ALL trial: MRC UKALL XII\/ECOG E2993","volume":"106","author":"Rowe","year":"2005","journal-title":"Blood"},{"issue":"4","key":"10.1016\/j.leukres.2019.106235_bib0055","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1586\/14737140.2015.1025256","article-title":"The role of ponatinib in Philadelphia chromosome-positive acute lymphoblastic leukemia","volume":"15","author":"Sanford","year":"2015","journal-title":"Expert Rev. Anticancer Ther."},{"issue":"6","key":"10.1016\/j.leukres.2019.106235_bib0060","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1016\/j.leukres.2007.10.019","article-title":"Outcome of treatment with Hyper-CVAD regimen in Chinese patients with acute lymphocytic leukemia","volume":"32","author":"Xu","year":"2008","journal-title":"Leuk. Res."},{"issue":"6","key":"10.1016\/j.leukres.2019.106235_bib0065","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1080\/10428190701343255","article-title":"Outcome of adult acute lymphoblastic leukemia with BFM protocol in a resource-constrained setting","volume":"48","author":"Malhotra","year":"2007","journal-title":"Leuk. Lymphoma"},{"issue":"3","key":"10.1016\/j.leukres.2019.106235_bib0070","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1159\/000351172","article-title":"Hyper-CVAD regimen in routine management of adult acute lymphoblastic leukemia: a retrospective multicenter study","volume":"130","author":"Buyukasik","year":"2013","journal-title":"Acta Haematol."},{"issue":"7","key":"10.1016\/j.leukres.2019.106235_bib0075","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1093\/jjco\/29.7.340","article-title":"Long-term follow-up results of adult patients with acute lymphocytic leukemia or lymphoblastic lymphoma treated with short-term, alternating non-cross-resistant chemotherapy: Japan Clinical Oncology Group Study 8702. Lymphoma Study Group","volume":"29","author":"Kobayashi","year":"1999","journal-title":"Jpn. J. Clin. Oncol."},{"issue":"suppl 5","key":"10.1016\/j.leukres.2019.106235_bib0080","doi-asserted-by":"crossref","first-page":"v69","DOI":"10.1093\/annonc\/mdw025","article-title":"Acute lymphoblastic leukaemia in adult patients: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up","volume":"27","author":"Hoelzer","year":"2016","journal-title":"Ann. Oncol."},{"issue":"5","key":"10.1016\/j.leukres.2019.106235_bib0085","doi-asserted-by":"crossref","first-page":"1646","DOI":"10.1182\/blood-2008-01-130237","article-title":"What determines the outcomes for adolescents and young adults with acute lymphoblastic leukemia treated on cooperative group protocols? A comparison of Children\u2019s Cancer Group and Cancer and Leukemia Group B studies","volume":"112","author":"Stock","year":"2008","journal-title":"Blood"},{"issue":"3","key":"10.1016\/j.leukres.2019.106235_bib0090","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1200\/JCO.2000.18.3.547","article-title":"Results of treatment with hyper-CVAD, a dose-intensive regimen, in adult acute lymphocytic leukemia","volume":"18","author":"Kantarjian","year":"2000","journal-title":"J. Clin. Oncol."},{"issue":"20","key":"10.1016\/j.leukres.2019.106235_bib0095","doi-asserted-by":"crossref","first-page":"4075","DOI":"10.1200\/JCO.2004.10.050","article-title":"Outcome of treatment in adults with acute lymphoblastic leukemia: analysis of the LALA-94 trial","volume":"22","author":"Thomas","year":"2004","journal-title":"J. Clin. Oncol."},{"issue":"7","key":"10.1016\/j.leukres.2019.106235_bib0100","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1038\/nrclinonc.2011.77","article-title":"Optimal therapy for acute lymphoblastic leukemia in adolescents and young adults","volume":"8","author":"Schafer","year":"2011","journal-title":"Nat. Rev. Clin. Oncol."},{"issue":"4","key":"10.1016\/j.leukres.2019.106235_bib0105","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1007\/BF02983559","article-title":"Immunophenotypes and outcome of Philadelphia chromosome-positive and -negative Thai adult acute lymphoblastic leukemia","volume":"78","author":"Udomsakdi-Auewarakul","year":"2003","journal-title":"Int. J. Hematol."},{"issue":"6","key":"10.1016\/j.leukres.2019.106235_bib0110","doi-asserted-by":"crossref","first-page":"e577","DOI":"10.1038\/bcj.2017.53","article-title":"Acute lymphoblastic leukemia: a comprehensive review and 2017 update","volume":"7","author":"Terwilliger","year":"2017","journal-title":"Blood Cancer J."},{"issue":"11","key":"10.1016\/j.leukres.2019.106235_bib0115","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.4065\/80.11.1517","article-title":"Adult acute lymphoblastic leukemia","volume":"80","author":"Jabbour","year":"2005","journal-title":"Mayo Clin. Proc."},{"issue":"15","key":"10.1016\/j.leukres.2019.106235_bib0120","doi-asserted-by":"crossref","first-page":"2517","DOI":"10.1002\/cncr.29383","article-title":"New insights into the pathophysiology and therapy of adult acute lymphoblastic leukemia","volume":"121","author":"Jabbour","year":"2015","journal-title":"Cancer."},{"issue":"2","key":"10.1016\/j.leukres.2019.106235_bib0125","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1182\/blood-2005-11-4666","article-title":"Central nervous system involvement in adult acute lymphoblastic leukemia at diagnosis: results from the international ALL trial MRC UKALL XII\/ECOG E2993","volume":"108","author":"Lazarus","year":"2006","journal-title":"Blood"},{"issue":"8","key":"10.1016\/j.leukres.2019.106235_bib0130","first-page":"3135","article-title":"Cytogenetic abnormalities in adult acute lymphoblastic leukemia: correlations with hematologic findings outcome. A Collaborative Study of the Group Francais de Cytogenetique Hematologique","volume":"87","year":"1996","journal-title":"Blood"},{"issue":"4","key":"10.1016\/j.leukres.2019.106235_bib0135","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1038\/sj.leu.2400959","article-title":"The impact of age on outcome in lymphoblastic leukaemia; MRC UKALL X and XA compared: a report from the MRC Paediatric and Adult Working Parties","volume":"12","author":"Chessells","year":"1998","journal-title":"Leukemia."},{"issue":"13","key":"10.1016\/j.leukres.2019.106235_bib0140","doi-asserted-by":"crossref","first-page":"2398","DOI":"10.1002\/cncr.30624","article-title":"Acute lymphoblastic leukemia in adolescents and young adults","volume":"123","author":"Rytting","year":"2017","journal-title":"Cancer"},{"key":"10.1016\/j.leukres.2019.106235_bib0145","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1182\/asheducation-2010.1.21","article-title":"Adolescents and young adults with acute lymphoblastic leukemia","volume":"2010","author":"Stock","year":"2010","journal-title":"Hematology Am. Soc. Hematol. Educ. Program"},{"issue":"4","key":"10.1016\/j.leukres.2019.106235_bib0150","doi-asserted-by":"crossref","first-page":"1827","DOI":"10.1182\/blood-2007-10-116582","volume":"111","author":"Goldstone","year":"2008","journal-title":"Blood"}],"container-title":["Leukemia Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145212619306800?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145212619306800?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T00:59:47Z","timestamp":1758934787000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0145212619306800"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":30,"alternative-id":["S0145212619306800"],"URL":"https:\/\/doi.org\/10.1016\/j.leukres.2019.106235","relation":{},"ISSN":["0145-2126"],"issn-type":[{"value":"0145-2126","type":"print"}],"subject":[],"published":{"date-parts":[[2019,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Better survivals in adolescent and Young adults, compared to adults with acute lymphoblastic leukemia \u2013 A multicenter prospective registry in Thai population","name":"articletitle","label":"Article Title"},{"value":"Leukemia Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.leukres.2019.106235","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"106235"}}