{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T01:40:12Z","timestamp":1758937212347,"version":"3.44.0"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Leukemia Research"],"published-print":{"date-parts":[[2024,3]]},"DOI":"10.1016\/j.leukres.2024.107457","type":"journal-article","created":{"date-parts":[[2024,2,15]],"date-time":"2024-02-15T00:17:42Z","timestamp":1707956262000},"page":"107457","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Adipose tissue indices predict prognosis in hodgkin lymphoma"],"prefix":"10.1016","volume":"138","author":[{"given":"Demircan","family":"\u00d6zbalc\u0131","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet","family":"Erdo\u011fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emine G\u00fc\u00e7han","family":"Alano\u011flu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sevim S\u00fcreyya","family":"\u015eeng\u00fcl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kamuran","family":"Y\u00fcceer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hande Nur","family":"Ero\u011flu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samet","family":"Ya\u011fc\u0131","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.leukres.2024.107457_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.blre.2022.100949","article-title":"A review of pathobiology and therapies for classic Hodgkin lymphoma","author":"Khan","year":"2022","journal-title":"Blood Rev."},{"key":"10.1016\/j.leukres.2024.107457_bib2","doi-asserted-by":"crossref","unstructured":"Connors J.M., Cozen W., Steidl C., Carbone A., Hoppe R.T., Flechtner H.H., et al. Hodgkin lymphoma. Nat Rev Dis Primers. 2020 Jul 23;6(1):61. doi:10.1038\/s41572-020-0189-6. Erratum in: Nat Rev Dis Primers. 2021 Oct 20;7(1):79. PMID: 32703953.","DOI":"10.1038\/s41572-020-0189-6"},{"issue":"12","key":"10.1016\/j.leukres.2024.107457_bib3","doi-asserted-by":"crossref","first-page":"e590","DOI":"10.3324\/haematol.2018.196782","article-title":"Interim PET-directed therapy in limited-stage Hodgkin lymphoma initially treated with ABVD","volume":"103","author":"Villa","year":"2018","journal-title":"Haematologica"},{"issue":"10","key":"10.1016\/j.leukres.2024.107457_bib4","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1182\/blood-2018-01-827246","article-title":"CALGB 50604: risk-adapted treatment of nonbulky early-stage Hodgkin lymphoma based on interim PET","volume":"132","author":"Straus","year":"2018","journal-title":"Blood"},{"issue":"3","key":"10.1016\/j.leukres.2024.107457_bib5","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1038\/s41375-021-01442-8","article-title":"Clinical outcomes of relapsed and refractory Hodgkin lymphoma patients after contemporary first-line treatment: a German Hodgkin Study Group analysis","volume":"36","author":"Br\u00f6ckelmann","year":"2022","journal-title":"Leukemia"},{"issue":"4","key":"10.1016\/j.leukres.2024.107457_bib6","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1111\/bjh.13634","article-title":"Evaluation of the International Prognostic Score (IPS-7) and a Simpler Prognostic Score (IPS-3) for advanced Hodgkin lymphoma in the modern era","volume":"171","author":"Diefenbach","year":"2015","journal-title":"Br. J. Haematol."},{"issue":"1","key":"10.1016\/j.leukres.2024.107457_bib7","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1111\/bjh.16293","article-title":"Validation of a simplified international prognostic score (IPS-3) in patients with advanced-stage classic Hodgkin lymphoma","volume":"189","author":"Hayden","year":"2020","journal-title":"Br. J. Haematol."},{"issue":"10","key":"10.1016\/j.leukres.2024.107457_bib8","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1016\/j.bbalip.2013.02.008","article-title":"Mechanisms linking obesity and cancer","volume":"1831","author":"Louie","year":"2013","journal-title":"Biochim Biophys. Acta"},{"issue":"10","key":"10.1016\/j.leukres.2024.107457_bib9","doi-asserted-by":"crossref","first-page":"13005","DOI":"10.1007\/s13277-016-5198-4","article-title":"Mechanisms underlying the association between obesity and Hodgkin lymphoma","volume":"37","author":"Matos","year":"2016","journal-title":"Tumour Biol."},{"issue":"1","key":"10.1016\/j.leukres.2024.107457_bib10","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.canlet.2016.06.010","article-title":"Adipocytes contribute to the growth and progression of multiple myeloma: Unraveling obesity related differences in adipocyte signalling","volume":"380","author":"Bullwinkle","year":"2016","journal-title":"Cancer Lett."},{"issue":"3","key":"10.1016\/j.leukres.2024.107457_bib11","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1002\/path.2711","article-title":"The classical Hodgkin's lymphoma microenvironment and its role in promoting tumour growth and immune escape","volume":"221","author":"Aldinucci","year":"2010","journal-title":"J. Pathol."},{"issue":"1","key":"10.1016\/j.leukres.2024.107457_bib12","first-page":"57","article-title":"Adipose tissue, obesity and adipokines: role in cancer promotion","volume":"21","author":"Booth","year":"2015","journal-title":"Horm. Mol. Biol. Clin. Invest."},{"issue":"21","key":"10.1016\/j.leukres.2024.107457_bib13","doi-asserted-by":"crossref","first-page":"6974","DOI":"10.1158\/1078-0432.CCR-08-1026","article-title":"Serum YKL-40 and interleukin 6 levels in Hodgkin lymphoma","volume":"14","author":"Biggar","year":"2008","journal-title":"Clin. Cancer Res"},{"issue":"10","key":"10.1016\/j.leukres.2024.107457_bib14","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1016\/j.leukres.2009.01.009","article-title":"Clinical significance of interleukin-10 gene polymorphisms and plasma levels in Hodgkin lymphoma","volume":"33","author":"Hohaus","year":"2009","journal-title":"Leuk. Res"},{"issue":"2","key":"10.1016\/j.leukres.2024.107457_bib15","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1200\/JCO.1995.13.2.403","article-title":"Bone marrow involvement in Hodgkin's disease: an analysis of 135 consecutive cases. German Hodgkin's Lymphoma study group","volume":"13","author":"Munker","year":"1995","journal-title":"J. Clin. Oncol."},{"issue":"11","key":"10.1016\/j.leukres.2024.107457_bib16","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1038\/nm.2492","article-title":"Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth","volume":"17","author":"Nieman","year":"2011","journal-title":"Nat. Med"},{"issue":"Pt 16","key":"10.1016\/j.leukres.2024.107457_bib17","doi-asserted-by":"crossref","first-page":"2681","DOI":"10.1242\/jcs.079699","article-title":"Adipogenesis at a glance","volume":"124","author":"Lowe","year":"2011","journal-title":"J. Cell Sci."},{"issue":"Pt 4","key":"10.1016\/j.leukres.2024.107457_bib18","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1042\/BST0350701","article-title":"Cathepsin K in the bone microenvironment: link between obesity and prostate cancer?","volume":"35","author":"Podgorski","year":"2007","journal-title":"Biochem Soc. Trans."},{"issue":"1123","key":"10.1016\/j.leukres.2024.107457_bib19","doi-asserted-by":"crossref","first-page":"20200672","DOI":"10.1259\/bjr.20200672","article-title":"Comparison between skeletal muscle and adipose tissue measurements with high-dose CT and low-dose attenuation correction CT of 18F-FDG PET\/CT in elderly Hodgkin lymphoma patients: a two-centre validation","volume":"94","author":"Albano","year":"2021","journal-title":"Br. J. Radio."},{"issue":"7","key":"10.1016\/j.leukres.2024.107457_bib20","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1038\/s41416-019-0401-1","article-title":"Body mass index and Hodgkin's lymphoma: UK population-based cohort study of 5.8 million individuals","volume":"120","author":"Strongman","year":"2019","journal-title":"Br. J. Cancer"},{"issue":"8","key":"10.1016\/j.leukres.2024.107457_bib21","first-page":"1103","article-title":"Obesity and the risk of Hodgkin lymphoma (United Kingdom)","volume":"17","author":"Willett","year":"2006","journal-title":"Cancer Causes Control"},{"issue":"1","key":"10.1016\/j.leukres.2024.107457_bib22","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1186\/s12967-021-03134-4","article-title":"Body mass index is not associated with survival outcomes and immune-related adverse events in patients with Hodgkin lymphoma treated with the immune checkpoint inhibitor nivolumab","volume":"19","author":"De Filippi","year":"2021","journal-title":"J. Transl. Med"},{"issue":"5","key":"10.1016\/j.leukres.2024.107457_bib23","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.trecan.2018.03.004","article-title":"Cancer as a Matter of Fat: The Crosstalk between Adipose Tissue and Tumors","volume":"4","author":"Lengyel","year":"2018","journal-title":"Trends Cancer"},{"issue":"3","key":"10.1016\/j.leukres.2024.107457_bib24","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1038\/s41574-018-0126-x","article-title":"The obese adipose tissue microenvironment in cancer development and progression","volume":"15","author":"Quail","year":"2019","journal-title":"Nat. Rev. Endocrinol."},{"issue":"11","key":"10.1016\/j.leukres.2024.107457_bib25","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1016\/j.acra.2013.08.012","article-title":"Accurate detection of metabolically active \"brown\" and \"white\" adipose tissues with computed tomography","volume":"20","author":"Ahmadi","year":"2013","journal-title":"Acad. Radio."},{"issue":"5","key":"10.1016\/j.leukres.2024.107457_bib26","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.tem.2014.03.002","article-title":"Lipolysis in lipid turnover, cancer cachexia, and obesity-induced insulin resistance","volume":"25","author":"Arner","year":"2014","journal-title":"Trends Endocrinol. Metab."},{"issue":"5","key":"10.1016\/j.leukres.2024.107457_bib27","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/j.cell.2011.02.013","article-title":"Hallmarks of cancer: the next generation","volume":"144","author":"Hanahan","year":"2011","journal-title":"Cell"},{"issue":"10","key":"10.1016\/j.leukres.2024.107457_bib28","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0140403","article-title":"Skeletal Muscle Depletion and Markers for Cancer Cachexia Are Strong Prognostic Factors in Epithelial Ovarian Cancer","volume":"10","author":"Aust","year":"2015","journal-title":"PLoS One"},{"issue":"21","key":"10.1016\/j.leukres.2024.107457_bib29","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1056\/NEJM199811193392104","article-title":"A prognostic score for advanced Hodgkin's disease. International Prognostic Factors Project on Advanced Hodgkin's Disease","volume":"339","author":"Hasenclever","year":"1998","journal-title":"N. Engl. J. Med"},{"issue":"4","key":"10.1016\/j.leukres.2024.107457_bib30","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1111\/bjh.13634","article-title":"Evaluation of the International Prognostic Score (IPS-7) and a Simpler Prognostic Score (IPS-3) for advanced Hodgkin lymphoma in the modern era","volume":"171","author":"Diefenbach","year":"2015","journal-title":"Br. J. Haematol."},{"issue":"1","key":"10.1016\/j.leukres.2024.107457_bib31","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.cell.2015.02.022","article-title":"Immune regulation of metabolic homeostasis in health and disease","volume":"161","author":"Brestoff","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.leukres.2024.107457_bib32","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.mrfmmm.2015.01.004","article-title":"Gene polymorphisms and increased DNA damage in morbidly obese women","volume":"776","author":"Luperini","year":"2015","journal-title":"Mutat. Res"},{"issue":"7","key":"10.1016\/j.leukres.2024.107457_bib33","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1172\/JCI27544","article-title":"A specific p47phox -serine phosphorylated by convergent MAPKs mediates neutrophil NADPH oxidase priming at inflammatory sites","volume":"116","author":"Dang","year":"2006","journal-title":"J. Clin. Invest"},{"issue":"14","key":"10.1016\/j.leukres.2024.107457_bib34","doi-asserted-by":"crossref","first-page":"1812","DOI":"10.1200\/JCO.2010.32.8401","article-title":"Molecular pathogenesis of Hodgkin's lymphoma: increasing evidence of the importance of the microenvironment","volume":"29","author":"Steidl","year":"2011","journal-title":"J. Clin. Oncol."},{"issue":"8","key":"10.1016\/j.leukres.2024.107457_bib35","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1182\/blood-2018-04-843714","article-title":"Mass cytometry of Hodgkin lymphoma reveals a CD4+ regulatory T-cell-rich and exhausted T-effector microenvironment.","volume":"132","author":"Cader","year":"2018","journal-title":"Blood"},{"issue":"8","key":"10.1016\/j.leukres.2024.107457_bib36","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1182\/blood.2019000847","article-title":"The immune landscape and response to immune checkpoint blockade therapy in lymphoma","volume":"135","author":"Kline","year":"2020","journal-title":"Blood"},{"issue":"4","key":"10.1016\/j.leukres.2024.107457_bib37","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1002\/hon.2887","article-title":"Perirenal and subcutaneous fat differently affect outcomes in newly diagnosed classical Hodgkin lymphoma patients","volume":"39","author":"Lucijanic","year":"2021","journal-title":"Hematol. Oncol."}],"container-title":["Leukemia Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145212624000237?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0145212624000237?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T01:04:30Z","timestamp":1758935070000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0145212624000237"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":37,"alternative-id":["S0145212624000237"],"URL":"https:\/\/doi.org\/10.1016\/j.leukres.2024.107457","relation":{},"ISSN":["0145-2126"],"issn-type":[{"type":"print","value":"0145-2126"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Adipose tissue indices predict prognosis in hodgkin lymphoma","name":"articletitle","label":"Article Title"},{"value":"Leukemia Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.leukres.2024.107457","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"107457"}}