{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T07:06:33Z","timestamp":1775027193771,"version":"3.50.1"},"reference-count":32,"publisher":"Elsevier BV","issue":"18","license":[{"start":{"date-parts":[[2004,3,1]],"date-time":"2004-03-01T00:00:00Z","timestamp":1078099200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2004,3]]},"DOI":"10.1016\/j.lfs.2003.10.005","type":"journal-article","created":{"date-parts":[[2004,1,28]],"date-time":"2004-01-28T17:47:27Z","timestamp":1075312047000},"page":"2327-2337","source":"Crossref","is-referenced-by-count":26,"title":["Estrogen-producing steroidogenic pathways in parietal cells of the rat gastric mucosa"],"prefix":"10.1016","volume":"74","author":[{"given":"Takashi","family":"Ueyama","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuyuki","family":"Shirasawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takao","family":"Ito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshihiro","family":"Tsuruo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1\u20132","key":"10.1016\/j.lfs.2003.10.005_BIB1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0303-7207(00)00383-X","article-title":"A guide to 17\u03b2-hydroxysteroid dehydrogenases","volume":"171","author":"Adamski","year":"2001","journal-title":"Molecular and Cellular Endocrinology"},{"issue":"5","key":"10.1016\/j.lfs.2003.10.005_BIB2","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1210\/en.137.5.1572","article-title":"Cloning of rat 17\u03b2-hydroxysteroid dehydrogenase type 2 and characterization of tissue distribution and catalytic activity of rat type 1 and type 2 enzymes","volume":"137","author":"Akinola","year":"1996","journal-title":"Endocrinology"},{"issue":"27","key":"10.1016\/j.lfs.2003.10.005_BIB3","doi-asserted-by":"crossref","first-page":"16249","DOI":"10.1016\/S0021-9258(18)71614-1","article-title":"Expression cloning and regulation of steroid 5\u03b1-reductase, an enzyme essential for male sexual differentiation","volume":"264","author":"Andersson","year":"1989","journal-title":"Journal of Biological Chemistry"},{"issue":"25","key":"10.1016\/j.lfs.2003.10.005_BIB4","doi-asserted-by":"crossref","first-page":"15959","DOI":"10.1074\/jbc.272.25.15959","article-title":"Expression cloning and characterization of oxidative 17\u03b2- and 3\u03b1-hydroxysteroid dehydrogenases from rat and human prostate","volume":"272","author":"Biswas","year":"1997","journal-title":"Journal of Biological Chemistry"},{"issue":"18","key":"10.1016\/j.lfs.2003.10.005_BIB5","doi-asserted-by":"crossref","first-page":"10461","DOI":"10.1074\/jbc.270.18.10461","article-title":"Molecular cloning and characterization of mouse estradiol 17\u03b2-dehydrogenase (A-specific), a member of the aldoketoreductase family","volume":"270","author":"Deyashiki","year":"1995","journal-title":"Journal of Biological Chemistry"},{"issue":"1","key":"10.1016\/j.lfs.2003.10.005_BIB6","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1172\/JCI113299","article-title":"Source of raised serum estrogens in male rats with portal bypass","volume":"81","author":"Farrell","year":"1988","journal-title":"Journal of Clinical Investigation"},{"issue":"3","key":"10.1016\/j.lfs.2003.10.005_BIB7","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1136\/gut.23.3.226","article-title":"Testosterone metabolism by the rat gastrointestinal tract, in vitro and in vivo","volume":"23","author":"Farthing","year":"1982","journal-title":"Gut"},{"issue":"1","key":"10.1016\/j.lfs.2003.10.005_BIB8","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1038\/ng0594-34","article-title":"Male pseudohermaphroditism caused by mutations of testicular 17\u03b2-hydroxysteroid dehydrogenase 3","volume":"7","author":"Geissler","year":"1994","journal-title":"Nature Genetics"},{"issue":"4","key":"10.1016\/j.lfs.2003.10.005_BIB9","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1210\/en.135.4.1477","article-title":"Rat 17\u03b2-hydroxysteroid dehydrogenase type 1: primary structure and regulation of enzyme expression in rat ovary by diethylstilbestrol and gonadotropins in vivo","volume":"135","author":"Ghersevich","year":"1994","journal-title":"Endocrinology"},{"issue":"1","key":"10.1016\/j.lfs.2003.10.005_BIB10","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1210\/mend-4-1-3","article-title":"Aromatase cytochrome P450 in rat ovarian granulosa cells before and after luteinization: adenosine 3\u2032, 5\u2032-monophosphate-dependent and independent regulation. Cloning and sequencing of rat aromatase cDNA and 5\u2032 genomic DNA","volume":"4","author":"Hickey","year":"1990","journal-title":"Molecular Endocrinology"},{"issue":"2","key":"10.1016\/j.lfs.2003.10.005_BIB11","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/0014-5793(90)81398-8","article-title":"Molecular cloning of a cDNA encoding aldosterone synthase cytochrome P-450 in rat adrenal cortex","volume":"263","author":"Imai","year":"1990","journal-title":"FEBS Letter"},{"issue":"3","key":"10.1016\/j.lfs.2003.10.005_BIB12","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1210\/endo-124-3-1417","article-title":"An enzyme-linked immunosorbent assay for quantitation of aromatase cytochrome P-450","volume":"124","author":"Kitawaki","year":"1989","journal-title":"Endocrinology"},{"issue":"4","key":"10.1016\/j.lfs.2003.10.005_BIB13","doi-asserted-by":"crossref","first-page":"1744","DOI":"10.1210\/en.136.4.1744","article-title":"Androgen biosynthesis in the stomach: expression of cytochrome P450 17\u03b1-hydroxylase\/17,20-lyase messenger ribonucleic acid and protein, and metabolism of pregnenolone and progesterone by parietal cells of the rat gastric mucosa","volume":"136","author":"Le Goascogne","year":"1995","journal-title":"Endocrinology"},{"issue":"3","key":"10.1016\/j.lfs.2003.10.005_BIB14","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1507\/endocrine1927.49.3_629","article-title":"Radioimmunoassay of sex steroids","volume":"49","author":"Makino","year":"1973","journal-title":"Folia Endocrinologica Japonica (in Japanese)"},{"issue":"4","key":"10.1016\/j.lfs.2003.10.005_BIB15","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1074\/jbc.270.4.1643","article-title":"P450c11B3 mRNA, transcribed from a third P450c11 gene, is expressed in a tissue-specific, developmentally, and hormonally regulated fashion in the rodent adrenal and encodes a protein with both 11-hydroxylase and 18-hydroxylase activities","volume":"270","author":"Mellon","year":"1995","journal-title":"Journal of Biological Chemistry"},{"issue":"2","key":"10.1016\/j.lfs.2003.10.005_BIB16","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1016\/S0006-291X(88)80307-3","article-title":"Rat testis P-450 17\u03b1 cDNA: the deduced amino acid sequence, expression and secondary structural configuration","volume":"157","author":"Namiki","year":"1988","journal-title":"Biochemical Biophysical Research Communications"},{"issue":"7","key":"10.1016\/j.lfs.2003.10.005_BIB17","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1210\/me.12.7.1048","article-title":"Expression cloning of a novel estrogenic mouse 17\u03b2-hydroxysteroid dehydrogenase\/17-ketosteroid reductase (m17HSD7), previously described as a prolactin receptor-associated protein (PRAP) in rat","volume":"12","author":"Nokelainen","year":"1998","journal-title":"Molecular Endocrinology"},{"issue":"6","key":"10.1016\/j.lfs.2003.10.005_BIB18","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1093\/nar\/11.6.1759","article-title":"The nucleotide sequence of the rat cytoplasmic \u03b2-actin gene","volume":"11","author":"Nudel","year":"1983","journal-title":"Nucleic Acids Research"},{"issue":"36","key":"10.1016\/j.lfs.2003.10.005_BIB19","doi-asserted-by":"crossref","first-page":"21934","DOI":"10.1016\/S0021-9258(20)88275-1","article-title":"Cyclic AMP-dependent and -independent regulation of cholesterol side chain cleavage cytochrome P-450 (P-450scc) in rat ovarian granulosa cells and corpora lutea. cDNA and deduced amino acid sequence of rat P-450scc","volume":"264","author":"Oonk","year":"1989","journal-title":"Journal of Biological Chemistry"},{"issue":"1\u20133","key":"10.1016\/j.lfs.2003.10.005_BIB20","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0039-128X(83)90058-2","article-title":"Immunoaffinity purification of aromatase cytochrome P-450 from human placental microsomes, metabolic switching from aromatization to 1\u03b2 and 2\u03b2-monohydroxylation, and recognition of aromatase isozymes","volume":"50","author":"Osawa","year":"1987","journal-title":"Steroids"},{"issue":"1","key":"10.1016\/j.lfs.2003.10.005_BIB21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1677\/jme.0.0230001","article-title":"17\u03b2-hydroxysteroid dehydrogenase (HSD)\/17-ketosteroid reductase (KSR) family; nomenclature and main characteristics of the 17HSD\/KSR enzymes","volume":"23","author":"Peltoketo","year":"1999","journal-title":"Journal of Molecular Endocrinology"},{"issue":"3","key":"10.1016\/j.lfs.2003.10.005_BIB22","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1210\/er.18.3.281","article-title":"Molecular endocrinology of hydroxysteroid dehydrogenases","volume":"18","author":"Penning","year":"1997","journal-title":"Endocrine Reviews"},{"issue":"3","key":"10.1016\/j.lfs.2003.10.005_BIB23","first-page":"342","article-title":"Aromatase cytochrome P450, the enzyme responsible for estrogen biosynthesis","volume":"15","author":"Simpson","year":"1994","journal-title":"Endocrine Reviews"},{"issue":"1","key":"10.1016\/j.lfs.2003.10.005_BIB24","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/0016-5085(91)90597-E","article-title":"The effect of portal-systemic shunting on hepatic sex hormone receptors in male rats","volume":"100","author":"Stauber","year":"1991","journal-title":"Gastroenterology"},{"issue":"23","key":"10.1016\/j.lfs.2003.10.005_BIB25","doi-asserted-by":"crossref","first-page":"15253","DOI":"10.1016\/S0021-9258(18)98610-2","article-title":"Molecular structure of rat hepatic 3\u03b1-hydroxysteroid dehydrogenase. A member of the oxidoreductase gene family","volume":"266","author":"Stolz","year":"1991","journal-title":"Journal of Biological Chemistry"},{"issue":"11","key":"10.1016\/j.lfs.2003.10.005_BIB26","doi-asserted-by":"crossref","first-page":"5275","DOI":"10.1210\/en.140.11.5275","article-title":"Complementary deoxyribonucleic acid cloning and enzymatic characterization of a novel 17\u03b2\/3\u03b1-hydroxysteroid\/retinoid short chain dehydrogenase\/reductase","volume":"140","author":"Su","year":"1999","journal-title":"Endocrinology"},{"issue":"1","key":"10.1016\/j.lfs.2003.10.005_BIB27","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/BF00305775","article-title":"Immunocytochemical localization of aromatase-containing neurons in the rat brain during pre- and postnatal development","volume":"278","author":"Tsuruo","year":"1994","journal-title":"Cell and Tissue Research"},{"issue":"8","key":"10.1016\/j.lfs.2003.10.005_BIB28","doi-asserted-by":"crossref","first-page":"3534","DOI":"10.1210\/en.140.8.3534","article-title":"The rat 17\u03b2-hydroxysteroid dehydrogenase type III: molecular cloning and gonadotropin regulation","volume":"140","author":"Tsai-Morris","year":"1999","journal-title":"Endocrinology"},{"issue":"8","key":"10.1016\/j.lfs.2003.10.005_BIB29","doi-asserted-by":"crossref","first-page":"3162","DOI":"10.1210\/en.143.8.3162","article-title":"Gastric parietal cells: potent endocrine role in secreting estrogen as a possible regulator of gastro-hepatic axis","volume":"143","author":"Ueyama","year":"2002","journal-title":"Endocrinology"},{"issue":"5","key":"10.1016\/j.lfs.2003.10.005_BIB30","first-page":"671","article-title":"Radioimmunoassay of androstenedione","volume":"22","author":"Yoshida","year":"1974","journal-title":"Clinical Endocrinology (in Japanese)"},{"issue":"1","key":"10.1016\/j.lfs.2003.10.005_BIB31","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/S0021-9258(18)52475-3","article-title":"Characterization of rat 3\u03b2-hydroxysteroid dehydrogenase\/\u03945-\u03944 isomerase cDNAs and differential tissue-specific expression of the corresponding mRNAs in steroidogenic and peripheral tissues","volume":"266","author":"Zhao","year":"1991","journal-title":"Journal of Biological Chemistry"},{"issue":"4","key":"10.1016\/j.lfs.2003.10.005_BIB32","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0960-0760(97)00040-X","article-title":"Cloning of two alternatively spliced 21-hydroxylase cDNAs from rat adrenal","volume":"62","author":"Zhou","year":"1997","journal-title":"Journal of Steroid Biochemistry Molecular Biology"}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002432050301186X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002432050301186X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,6,14]],"date-time":"2021-06-14T04:47:03Z","timestamp":1623646023000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002432050301186X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,3]]},"references-count":32,"journal-issue":{"issue":"18","published-print":{"date-parts":[[2004,3]]}},"alternative-id":["S002432050301186X"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2003.10.005","relation":{},"ISSN":["0024-3205"],"issn-type":[{"value":"0024-3205","type":"print"}],"subject":[],"published":{"date-parts":[[2004,3]]}}}