{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T09:39:19Z","timestamp":1789724359103,"version":"4.0.1"},"reference-count":42,"publisher":"Elsevier BV","issue":"13","license":[{"start":{"date-parts":[[2004,8,1]],"date-time":"2004-08-01T00:00:00Z","timestamp":1091318400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2004,8]]},"DOI":"10.1016\/j.lfs.2004.02.030","type":"journal-article","created":{"date-parts":[[2004,6,17]],"date-time":"2004-06-17T17:06:22Z","timestamp":1087491982000},"page":"1539-1549","source":"Crossref","is-referenced-by-count":96,"title":["Molecular process in acute liver injury and regeneration induced by carbon tetrachloride"],"prefix":"10.1016","volume":"75","author":[{"given":"Makoto","family":"Taniguchi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiyuki","family":"Takeuchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryusuke","family":"Nakatsuka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsuo","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenzo","family":"Sato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.lfs.2004.02.030_BIB1","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/0092-8674(91)90098-J","article-title":"ERKs: a family of protein-serine\/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF","volume":"65","author":"Boulton","year":"1991","journal-title":"Cell"},{"key":"10.1016\/j.lfs.2004.02.030_BIB2","first-page":"253","article-title":"DNA bases attack by reactive metabolites produced during carbon tetrachloride biotransformation and promotion of liver microsomal lipid peroxidation","volume":"95","author":"Castro","year":"1997","journal-title":"Research Communications in Molecular Pathology and Pharmacology"},{"key":"10.1016\/j.lfs.2004.02.030_BIB3","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1126\/science.2981433","article-title":"Prooxidant states and tumor promotion","volume":"227","author":"Cerutti","year":"1985","journal-title":"Science"},{"key":"10.1016\/j.lfs.2004.02.030_BIB4","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1006\/abio.1987.9999","article-title":"Single-step method of RNA isolation by acid guanidinium thiocynate-phenolchloroform extraction","volume":"162","author":"Chomzynski","year":"1987","journal-title":"Analytical Biochemistry"},{"key":"10.1016\/j.lfs.2004.02.030_BIB5","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1016\/S0076-6879(02)49345-7","article-title":"Transcription regulation of manganese superoxide dismutase gene","volume":"349","author":"Clair","year":"2002","journal-title":"Methods in Enzymology"},{"key":"10.1016\/j.lfs.2004.02.030_BIB6","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1210\/en.141.1.153","article-title":"NF-\u03baB is required for cytokine-induced manganese superoxide dismutase expression in insulin-producing cells","volume":"141","author":"Darville","year":"2000","journal-title":"Endocrinology"},{"key":"10.1016\/j.lfs.2004.02.030_BIB7","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1034\/j.1600-0528.2002.017411.x","article-title":"Cytokine regulation of liver injury and repair","volume":"174","author":"Diehl","year":"2000","journal-title":"Immunological Reviews"},{"key":"10.1016\/j.lfs.2004.02.030_BIB8","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1006\/taap.1993.1069","article-title":"The involvement of Kupffer cells in carbon tetrachloride toxicity","volume":"119","author":"Edwards","year":"1993","journal-title":"Toxicology and Applied Pharmacology"},{"key":"10.1016\/j.lfs.2004.02.030_BIB9","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1096\/fasebj.9.15.8529831","article-title":"Liver regeneration 2. Role of growth factors and cytokines in hepatic regeneration","volume":"9","author":"Fausto","year":"1995","journal-title":"FASEB Journal"},{"key":"10.1016\/j.lfs.2004.02.030_BIB10","doi-asserted-by":"crossref","first-page":"1419","DOI":"10.1056\/NEJM199711133372003","article-title":"Pathophysiology of premature skin aging induced by ultraviolet light","volume":"337","author":"Fisher","year":"1997","journal-title":"New England Journal of Medicine"},{"key":"10.1016\/j.lfs.2004.02.030_BIB11","doi-asserted-by":"crossref","first-page":"4571","DOI":"10.1128\/MCB.12.10.4571","article-title":"In vivo transcriptional analysis of TATA-less promoter of Drosophila melanogaster vermilion gene","volume":"12","author":"Fridell","year":"1992","journal-title":"Molecular and Cellular Biology"},{"key":"10.1016\/j.lfs.2004.02.030_BIB12","doi-asserted-by":"crossref","first-page":"23142","DOI":"10.1016\/S0021-9258(18)54474-4","article-title":"Phorbol ester induces manganese-superoxide dismutase in tumor necrosis factor-resistant cells","volume":"266","author":"Fujii","year":"1991","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.lfs.2004.02.030_BIB13","series-title":"Free Radical Damage and its control","author":"Fruchart","year":"1994"},{"key":"10.1016\/j.lfs.2004.02.030_BIB14","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/S0168-8278(02)00108-3","article-title":"Hepatobiliary organic anion transporters are differentially regulated in acute toxic liver injury induced by carbon tetrachloride","volume":"37","author":"Geier","year":"2002","journal-title":"Journal of Hepatology"},{"key":"10.1016\/j.lfs.2004.02.030_BIB15","doi-asserted-by":"crossref","first-page":"5794","DOI":"10.1073\/pnas.77.10.5794","article-title":"Isolation and characterization of the Drosophila alchol dehydrogenase gene","volume":"77","author":"Goldberg","year":"1980","journal-title":"Proceedings of the National Academy of Sciences USA"},{"key":"10.1016\/j.lfs.2004.02.030_BIB16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0898-6568(98)00037-0","article-title":"Redox regulation of cellular signaling","volume":"11","author":"Kamata","year":"1999","journal-title":"Cellular Signaling"},{"key":"10.1016\/j.lfs.2004.02.030_BIB17","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1016\/0006-291X(89)92733-2","article-title":"Marked increase of HGF mRNA in non-parenchymal liver cells of rats treated with hepatotoxins","volume":"165","author":"Kinoshita","year":"1989","journal-title":"Biochemical and Biophysical Research Communications"},{"key":"10.1016\/j.lfs.2004.02.030_BIB18","first-page":"819","article-title":"Tumor necrosis factor induces DNA replication in hepatic cells through nuclear factor \u03baB activation","volume":"10","author":"Kirillova","year":"1999","journal-title":"Cell Growth and Differentiation"},{"key":"10.1016\/j.lfs.2004.02.030_BIB19","doi-asserted-by":"crossref","first-page":"4683","DOI":"10.1073\/pnas.89.10.4683","article-title":"Expression of interleukin 1-inducible genes and production of interleukin 1 by aging human fibroblasts","volume":"89","author":"Kumar","year":"1992","journal-title":"Proceedings of the National Academy of Sciences USA"},{"key":"10.1016\/j.lfs.2004.02.030_BIB20","first-page":"27","article-title":"Hepatocyte growth factor: molecular structure, roles in liver regeneration, and other biological functions","volume":"3","author":"Matsumoto","year":"1992","journal-title":"Critical Reviews in Oncogenesis"},{"key":"10.1016\/j.lfs.2004.02.030_BIB21","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1056\/NEJM198501173120305","article-title":"Oxygen-derived free radicals in postischemic tissue injury","volume":"312","author":"McCord","year":"1985","journal-title":"New England Journal of Medicine"},{"key":"10.1016\/j.lfs.2004.02.030_BIB22","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1016\/0006-291X(89)92316-4","article-title":"Molecular cloning and sequence analysis of cDNA for human hepatocyte growth factor","volume":"163","author":"Miyazawa","year":"1989","journal-title":"Biochemical and Biophysical Research Communications"},{"key":"10.1016\/j.lfs.2004.02.030_BIB23","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1128\/MCB.22.4.1060-1072.2002","article-title":"Activation of NF-\u03baB is essential for hepatocyte growth factor-mediated proliferation and tubulogenesis","volume":"22","author":"M\u00fcller","year":"2003","journal-title":"Molecular and Cellular Biology"},{"key":"10.1016\/j.lfs.2004.02.030_BIB24","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0304-3940(99)00532-7","article-title":"Age-related decrease in brain-derived neurotrophic factor gene expression in the brain of the zitter rat with genetic spondiform encephalopathy","volume":"271","author":"Muto","year":"1999","journal-title":"Neuroscience Letters"},{"key":"10.1016\/j.lfs.2004.02.030_BIB25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0014-5793(99)01202-8","article-title":"Hepatoprotective action of adenovirus-transferred HNF-3\u03b3 gene in acute liver injury caused by CCl4","volume":"459","author":"Nakamura","year":"1999","journal-title":"FEBS Letters"},{"key":"10.1016\/j.lfs.2004.02.030_BIB26","first-page":"1241","article-title":"Protective action of hepatocyte growth factor for acute liver injury caused by D-galactosamine in transgenic mice","volume":"26","author":"Okano","year":"1997","journal-title":"Hepatology"},{"key":"10.1016\/j.lfs.2004.02.030_BIB27","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1046\/j.1523-1747.1999.00465.x","article-title":"Adaptive antioxidant response of manganese-superoxide dismutase following repetitive UVA irradiation","volume":"112","author":"Poswig","year":"1999","journal-title":"Journal of Investigative Dermatology"},{"key":"10.1016\/j.lfs.2004.02.030_BIB28","doi-asserted-by":"crossref","first-page":"14264","DOI":"10.1074\/jbc.M100199200","article-title":"Manganese superoxide dismutase signals matrix metalloproteinase expression via H2O2-dependent ERK1\/2 activation","volume":"276","author":"Ranganathan","year":"2001","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.lfs.2004.02.030_BIB29","doi-asserted-by":"crossref","first-page":"3898","DOI":"10.1093\/emboj\/cdg379","article-title":"NF-\u03baB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death","volume":"22","author":"Sakon","year":"2003","journal-title":"EMBO Journal"},{"key":"10.1016\/j.lfs.2004.02.030_BIB30","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1111\/j.1751-1097.1997.tb01914.x","article-title":"Effects of a single exposure to UVB radiation on the activities and protein levels of copper-zinc and manganese superoxide dismutase in cultured human keratinocytes","volume":"65","author":"Sasaki","year":"1997","journal-title":"Photochemistry and Photobiology"},{"key":"10.1016\/j.lfs.2004.02.030_BIB31","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1007\/s007950050026","article-title":"The protective effect of hepatocyte growth-promoting factor (pHGF) against carbon tetrachloride-induced acute liver injury in rats: an ultrastructural study","volume":"32","author":"Sato","year":"1999","journal-title":"Medical Electron Microscopy"},{"key":"10.1016\/j.lfs.2004.02.030_BIB32","first-page":"363","volume":"vol. 13","author":"Schoenbaum","year":"1976"},{"key":"10.1016\/j.lfs.2004.02.030_BIB33","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0300-483X(99)00087-6","article-title":"Pathophysiological mechanisms of TNF during intoxication with natural or man-made toxins","volume":"138","author":"Schumann","year":"1999","journal-title":"Toxicology"},{"key":"10.1016\/j.lfs.2004.02.030_BIB34","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1021\/tx9900371","article-title":"Metabolism of carbon tetrachloride to trichloromethyl radical: An ESR and HPLC-EC study","volume":"12","author":"Stoyanovsky","year":"1999","journal-title":"Chemical Research in Toxicology"},{"key":"10.1016\/j.lfs.2004.02.030_BIB35","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1093\/oxfordjournals.jbchem.a022830","article-title":"Multiple elements for negative regulation of the rat catalase gene expression in dedifferentiated hepatoma cells","volume":"128","author":"Takeuchi","year":"2000","journal-title":"Journal of Biochemistry (Tokyo)"},{"key":"10.1016\/j.lfs.2004.02.030_BIB36","doi-asserted-by":"crossref","first-page":"3122","DOI":"10.1128\/MCB.9.7.3122","article-title":"Tissue-specific in vitro transcription from the mouse myelin basic protein promoter","volume":"9","author":"Tamura","year":"1989","journal-title":"Molecular and Cellular Biology"},{"key":"10.1016\/j.lfs.2004.02.030_BIB37","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1093\/oxfordjournals.jbchem.a021691","article-title":"Inverted repeats in the TATA-less promoter of the rat catalase gene","volume":"121","author":"Toda","year":"1997","journal-title":"Journal of Biochemistry (Tokyo)"},{"key":"10.1016\/j.lfs.2004.02.030_BIB38","doi-asserted-by":"crossref","first-page":"4350","DOI":"10.1073\/pnas.76.9.4350","article-title":"Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose lose sheets: procedure and some applications","volume":"76","author":"Towbin","year":"1979","journal-title":"Proceedings of the National Academy of Sciences USA"},{"key":"10.1016\/j.lfs.2004.02.030_BIB39","doi-asserted-by":"crossref","first-page":"2008","DOI":"10.1126\/science.270.5244.2008","article-title":"Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction","volume":"270","author":"Yamaguchi","year":"1995","journal-title":"Science"},{"key":"10.1016\/j.lfs.2004.02.030_BIB40","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1016\/0006-291X(92)92315-O","article-title":"Depression of catalase gene expression in the liver of tumor bearing nude mice","volume":"189","author":"Yamaguchi","year":"1992","journal-title":"Biochemical and Biophysical Research Communications"},{"key":"10.1016\/j.lfs.2004.02.030_BIB41","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0306-9877(94)90070-1","article-title":"The pathophysiology of reactive oxygen intermediates in the central nervous system","volume":"43","author":"Weber","year":"1994","journal-title":"Medical Hypotheses"},{"key":"10.1016\/j.lfs.2004.02.030_BIB42","doi-asserted-by":"crossref","first-page":"6768","DOI":"10.1073\/pnas.92.15.6768","article-title":"Competence for collagenase gene expression by tissue fibroblasts requires activation of an interleukin 1 alpha autocrine loop","volume":"92","author":"West-Mays","year":"1995","journal-title":"Proceedings of the National Academy of Sciences USA"}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002432050400462X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002432050400462X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,6,23]],"date-time":"2021-06-23T12:17:01Z","timestamp":1624450621000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002432050400462X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,8]]},"references-count":42,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2004,8]]}},"alternative-id":["S002432050400462X"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2004.02.030","relation":{},"ISSN":["0024-3205"],"issn-type":[{"value":"0024-3205","type":"print"}],"subject":[],"published":{"date-parts":[[2004,8]]}}}