{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T21:42:01Z","timestamp":1778276521809,"version":"3.51.4"},"reference-count":28,"publisher":"Elsevier BV","issue":"20","license":[{"start":{"date-parts":[[2006,4,1]],"date-time":"2006-04-01T00:00:00Z","timestamp":1143849600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2006,4]]},"DOI":"10.1016\/j.lfs.2005.09.052","type":"journal-article","created":{"date-parts":[[2005,12,8]],"date-time":"2005-12-08T12:14:25Z","timestamp":1134044065000},"page":"2295-2301","source":"Crossref","is-referenced-by-count":73,"title":["Expression of FGF23 is correlated with serum phosphate level in isolated fibrous dysplasia"],"prefix":"10.1016","volume":"78","author":[{"given":"Keisuke","family":"Kobayashi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuo","family":"Imanishi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Koshiyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akimitsu","family":"Miyauchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenichi","family":"Wakasa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takehisa","family":"Kawata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hitoshi","family":"Goto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirotsugu","family":"Ohashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hajime M.","family":"Koyano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryuichi","family":"Mochizuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takami","family":"Miki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaaki","family":"Inaba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiki","family":"Nishizawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.lfs.2005.09.052_bib1","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1172\/JCI2361","article-title":"Reproduction of human fibrous dysplasia of bone in immunocompromised mice by transplanted mosaics of normal and Gs alpha-mutated skeletal progenitor cells","volume":"101","author":"Bianco","year":"1998","journal-title":"Journal of Clinical Investigation"},{"key":"10.1016\/j.lfs.2005.09.052_bib2","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1359\/jbmr.2000.15.1.120","article-title":"Mutations of the GNAS1 gene, stromal cell dysfunction, and osteomalacic changes in non-McCune\u2013Albright fibrous dysplasia of bone","volume":"15","author":"Bianco","year":"2000","journal-title":"Journal of Bone and Mineral Research"},{"key":"10.1016\/j.lfs.2005.09.052_bib3","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1359\/jbmr.2001.16.5.806","article-title":"Renal phosphate wasting in fibrous dysplasia of bone is part of a generalized renal tubular dysfunction similar to that seen in tumor-induced osteomalacia","volume":"16","author":"Collins","year":"2001","journal-title":"Journal of Bone and Mineral Research"},{"key":"10.1016\/j.lfs.2005.09.052_bib4","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1359\/jbmr.2003.18.7.1235","article-title":"Osteomalacic and hyperparathyroid changes in fibrous dysplasia of bone: core biopsy studies and clinical correlations","volume":"18","author":"Corsi","year":"2003","journal-title":"Journal of Bone and Mineral Research"},{"key":"10.1016\/j.lfs.2005.09.052_bib5","first-page":"411","article-title":"Hypophosphataemic osteomalacia in fibrous dysplasia","volume":"45","author":"Dent","year":"1976","journal-title":"Quarterly Journal of Medicine"},{"key":"10.1016\/j.lfs.2005.09.052_bib6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00000478-200401000-00001","article-title":"Most osteomalacia-associated mesenchymal tumors are a single histopathologic entity: an analysis of 32 cases and a comprehensive review of the literature","volume":"28","author":"Folpe","year":"2004","journal-title":"American Journal of Surgical Pathology"},{"key":"10.1016\/j.lfs.2005.09.052_bib7","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1111\/j.1399-0004.1986.tb01261.x","article-title":"The McCune\u2013Albright syndrome: a lethal gene surviving by mosaicism","volume":"29","author":"Happle","year":"1986","journal-title":"Clinical Genetics"},{"key":"10.1016\/j.lfs.2005.09.052_bib8","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.1097\/01.ASN.0000018148.50109.C0","article-title":"Clonal chromosomal defects in the molecular pathogenesis of refractory hyperparathyroidism of uremia","volume":"13","author":"Imanishi","year":"2002","journal-title":"Journal of the American Society of Nephrology"},{"key":"10.1016\/j.lfs.2005.09.052_bib9","doi-asserted-by":"crossref","first-page":"1943","DOI":"10.1111\/j.1523-1755.2004.00604.x","article-title":"FGF-23 in patients with end-stage renal disease on hemodialysis","volume":"65","author":"Imanishi","year":"2004","journal-title":"Kidney International"},{"key":"10.1016\/j.lfs.2005.09.052_bib10","doi-asserted-by":"crossref","first-page":"1656","DOI":"10.1056\/NEJMoa020881","article-title":"Fibroblast growth factor 23 in oncogenic osteomalacia and X-linked hypophosphatemia","volume":"348","author":"Jonsson","year":"2003","journal-title":"New England Journal of Medicine"},{"key":"10.1016\/j.lfs.2005.09.052_bib11","doi-asserted-by":"crossref","unstructured":"Kobayashi, K., Imanishi, Y., Miyauchi, A., Onoda, N., Kawata, T., Tahara, H., Goto, H., Miki, T., Ishimura, E., Sugimoto, T., Ishikawa, T., Inaba M., Nishizawa, Y., in press. Regulation of plasma fibroblast growth factor 23 by calcium in primary hyperparathyroidism. European Journal of Endocrinology.","DOI":"10.1530\/eje.1.02053"},{"key":"10.1016\/j.lfs.2005.09.052_bib12","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1038\/340692a0","article-title":"GTPase inhibiting mutations activate the alpha chain of Gs and stimulate adenylyl cyclase in human pituitary tumours","volume":"340","author":"Landis","year":"1989","journal-title":"Nature"},{"key":"10.1016\/j.lfs.2005.09.052_bib13","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1530\/eje.0.1480269","article-title":"Immunohistochemical detection of FGF-23 protein in tumors that cause oncogenic osteomalacia","volume":"148","author":"Larsson","year":"2003","journal-title":"European Journal of Endocrinology"},{"key":"10.1016\/j.lfs.2005.09.052_bib14","doi-asserted-by":"crossref","first-page":"2980","DOI":"10.1001\/jama.256.21.2980","article-title":"McCune\u2013Albright syndrome. Long-term follow-up","volume":"256","author":"Lee","year":"1986","journal-title":"JAMA"},{"key":"10.1016\/j.lfs.2005.09.052_bib15","first-page":"1059","article-title":"Increased proliferation of osteoblastic cells expressing the activating Gs alpha mutation in monostotic and polyostotic fibrous dysplasia","volume":"150","author":"Marie","year":"1997","journal-title":"American Journal of Pathology"},{"key":"10.1016\/j.lfs.2005.09.052_bib16","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1210\/jcem-67-1-46","article-title":"Hemangiopericytoma-induced osteomalacia: tumor transplantation in nude mice causes hypophosphatemia and tumor extracts inhibit renal 25-hydroxyvitamin D 1-hydroxylase activity","volume":"67","author":"Miyauchi","year":"1988","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"10.1016\/j.lfs.2005.09.052_bib17","first-page":"1587","article-title":"Fibrous dysplasia of bone in the McCune\u2013Albright syndrome: abnormalities in bone formation","volume":"151","author":"Riminucci","year":"1997","journal-title":"American Journal of Pathology"},{"key":"10.1016\/j.lfs.2005.09.052_bib18","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1002\/(SICI)1096-9896(199901)187:2<249::AID-PATH222>3.0.CO;2-J","article-title":"The histopathology of fibrous dysplasia of bone in patients with activating mutations of the Gs alpha gene: site-specific patterns and recurrent histological hallmarks","volume":"187","author":"Riminucci","year":"1999","journal-title":"Journal of Pathology"},{"key":"10.1016\/j.lfs.2005.09.052_bib19","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1172\/JCI18399","article-title":"FGF-23 in fibrous dysplasia of bone and its relationship to renal phosphate wasting","volume":"112","author":"Riminucci","year":"2003","journal-title":"Journal of Clinical Investigation"},{"key":"10.1016\/j.lfs.2005.09.052_bib20","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1016\/0026-0495(68)90004-8","article-title":"Fibrous dysplasia of bone with vitamin D resistant rickets: a case study.","volume":"17","author":"Ryan","year":"1968","journal-title":"Metabolism"},{"key":"10.1016\/j.lfs.2005.09.052_bib21","doi-asserted-by":"crossref","first-page":"6500","DOI":"10.1073\/pnas.101545198","article-title":"Cloning and characterization of FGF23 as a causative factor of tumor-induced osteomalacia","volume":"98","author":"Shimada","year":"2001","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1016\/j.lfs.2005.09.052_bib22","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1146\/annurev.ph.58.030196.001043","article-title":"Defects in G protein-coupled signal transduction in human disease","volume":"58","author":"Spiegel","year":"1996","journal-title":"Annual Review of Physiology"},{"key":"10.1016\/j.lfs.2005.09.052_bib23","doi-asserted-by":"crossref","first-page":"2434","DOI":"10.1210\/jc.81.7.2434","article-title":"Mutations in G proteins and G protein-coupled receptors in endocrine disease","volume":"81","author":"Spiegel","year":"1996","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"10.1016\/j.lfs.2005.09.052_bib24","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1038\/81664","article-title":"Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23","volume":"26","author":"The ADHR Consortium","year":"2000","journal-title":"Nature Genetics"},{"key":"10.1016\/j.lfs.2005.09.052_bib25","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.1056\/NEJM199112123252403","article-title":"Activating mutations of the stimulatory G protein in the McCune\u2013Albright syndrome","volume":"325","author":"Weinstein","year":"1991","journal-title":"New England Journal of Medicine"},{"key":"10.1016\/j.lfs.2005.09.052_bib26","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1046\/j.1523-1755.2001.00064.x","article-title":"Autosomal-dominant hypophosphatemic rickets (ADHR) mutations stabilize FGF-23","volume":"60","author":"White","year":"2001","journal-title":"Kidney International"},{"key":"10.1016\/j.lfs.2005.09.052_bib27","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1210\/jc.86.2.497","article-title":"The autosomal dominant hypophosphatemic rickets (ADHR) gene is a secreted polypeptide overexpressed by tumors that cause phosphate wasting","volume":"86","author":"White","year":"2001","journal-title":"Journal of Clinical Endocrinology and Metabolism"},{"key":"10.1016\/j.lfs.2005.09.052_bib28","doi-asserted-by":"crossref","first-page":"4957","DOI":"10.1210\/jc.2002-021105","article-title":"Increased circulatory level of biologically active full-length FGF-23 in patients with hypophosphatemic rickets\/osteomalacia","volume":"87","author":"Yamazaki","year":"2002","journal-title":"Journal of Clinical Endocrinology and Metabolism"}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320505011586?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320505011586?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,9]],"date-time":"2019-04-09T19:26:45Z","timestamp":1554838005000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0024320505011586"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,4]]},"references-count":28,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2006,4]]}},"alternative-id":["S0024320505011586"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2005.09.052","relation":{},"ISSN":["0024-3205"],"issn-type":[{"value":"0024-3205","type":"print"}],"subject":[],"published":{"date-parts":[[2006,4]]}}}