{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T12:27:04Z","timestamp":1766579224694},"reference-count":40,"publisher":"Elsevier BV","issue":"26","license":[{"start":{"date-parts":[[2006,5,1]],"date-time":"2006-05-01T00:00:00Z","timestamp":1146441600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2006,5]]},"DOI":"10.1016\/j.lfs.2005.11.030","type":"journal-article","created":{"date-parts":[[2006,2,4]],"date-time":"2006-02-04T15:52:41Z","timestamp":1139068361000},"page":"3018-3026","source":"Crossref","is-referenced-by-count":14,"title":["Involvement of AE3 isoform of Na+-independent Cl\u2212\/HCO3\u2212 exchanger in myocardial pHi recovery from intracellular alkalization"],"prefix":"10.1016","volume":"78","author":[{"given":"Gladys E.","family":"Chiappe de Cingolani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irene L.","family":"Ennis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricio E.","family":"Morgan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bernardo V.","family":"Alvarez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph R.","family":"Casey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda C.","family":"Camili\u00f3n de Hurtado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"Suppl 5","key":"10.1016\/j.lfs.2005.11.030_bib1","first-page":"S41","article-title":"The AE gene family of Cl\u2212\/HCO3\u2212 exchangers","volume":"15","author":"Alper","year":"2002","journal-title":"Journal of Nephrology"},{"key":"10.1016\/j.lfs.2005.11.030_bib2","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1161\/hh2401.101907","article-title":"Molecular basis for angiotensin II-induced increase of chloride\/bicarbonate exchange in the myocardium","volume":"89","author":"Alvarez","year":"2001","journal-title":"Circulation Research"},{"key":"10.1016\/j.lfs.2005.11.030_bib3","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1113\/jphysiol.2004.077339","article-title":"Slc26a6: a cardiac chloride-hydroxyl exchanger and predominant chloride-bicarbonate exchanger of the mouse heart","volume":"561","author":"Alvarez","year":"2004","journal-title":"Journal of Physiology (London)"},{"key":"10.1016\/j.lfs.2005.11.030_bib4","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1113\/jphysiol.1989.sp017833","article-title":"Effect of intracellular and extracellular pH on contraction in isolated, mammalian cardiac muscle","volume":"418","author":"Bountra","year":"1989","journal-title":"Journal of Physiology (London)"},{"key":"10.1016\/j.lfs.2005.11.030_bib5","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/BF01870088","article-title":"Membrane proteins related to anion permeability of human red blood cells. I. Localization of disulfonic stilbene binding sites in proteins involved in permeation","volume":"15","author":"Cabantchik","year":"1974","journal-title":"Journal of Membrane Biology"},{"key":"10.1016\/j.lfs.2005.11.030_bib6","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1161\/01.RES.82.4.473","article-title":"Angiotensin II activates Na+-independent Cl\u2212\/HCO3\u2212 exchange in ventricular myocardium","volume":"82","author":"Camili\u00f3n de Hurtado","year":"1998","journal-title":"Circulation Research"},{"key":"10.1016\/j.lfs.2005.11.030_bib7","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1161\/01.RES.86.6.622","article-title":"Stimulation of myocardial Na+-independent Cl\u2212\/HCO3\u2212 exchanger by angiotensin II is mediated by endogenous endothelin","volume":"86","author":"Camili\u00f3n de Hurtado","year":"2000","journal-title":"Circulation Research"},{"key":"10.1016\/j.lfs.2005.11.030_bib8","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1006\/jmcc.2002.2107","article-title":"Upregulation of myocardial Na+\/H+ exchanger induced by chronic treatment with a selective inhibitor","volume":"34","author":"Camili\u00f3n de Hurtado","year":"2002","journal-title":"Journal of Molecular and Cellular Cardiology"},{"key":"10.1016\/j.lfs.2005.11.030_bib9","doi-asserted-by":"crossref","first-page":"8521","DOI":"10.1074\/jbc.270.15.8521","article-title":"The role of cysteine residues in the erythrocyte plasma membrane anion exchange protein, AE1","volume":"270","author":"Casey","year":"1995","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.lfs.2005.11.030_bib10","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0008-6363(01)00276-0","article-title":"Hyperactivity and altered expression mRNA isoform of the Cl\u2212\/HCO3\u2212 anion exchanger in the hypertrophied myocardium","volume":"51","author":"Chiappe de Cingolani","year":"2001","journal-title":"Cardiovascular Research"},{"key":"10.1016\/j.lfs.2005.11.030_bib11","doi-asserted-by":"crossref","first-page":"1082","DOI":"10.1161\/01.RES.0000102408.25664.01","article-title":"Influence of Na+-independent Cl\u2212\/HCO3\u2212 exchange on the slow force response to myocardial stretch","volume":"93","author":"Cingolani","year":"2003","journal-title":"Circulation Research"},{"key":"10.1016\/j.lfs.2005.11.030_bib12","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1161\/01.RES.75.5.862","article-title":"Chloride dependence of pH modulation by \u03b2-adrenergic agonist in rat cardiomyocytes","volume":"75","author":"Desilets","year":"1994","journal-title":"Circulation Research"},{"key":"10.1016\/j.lfs.2005.11.030_bib13","doi-asserted-by":"crossref","first-page":"1883","DOI":"10.1093\/hmg\/8.10.1883","article-title":"A family of mammalian anion transporters and their involvement in human genetic diseases","volume":"8","author":"Everett","year":"1999","journal-title":"Human Molecular Genetics"},{"key":"10.1016\/j.lfs.2005.11.030_bib14","doi-asserted-by":"crossref","first-page":"2606","DOI":"10.1021\/bi00789a030","article-title":"Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane","volume":"10","author":"Fairbanks","year":"1971","journal-title":"Biochemistry"},{"key":"10.1016\/j.lfs.2005.11.030_bib15","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1042\/bj20030007","article-title":"Transport activity of chimaeric AE2-AE3 chloride\/bicarbonate anion exchange proteins","volume":"371","author":"Fujinaga","year":"2003","journal-title":"Biochemical Journal"},{"key":"10.1016\/j.lfs.2005.11.030_bib16","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1038\/337648a0","article-title":"Arginine vasopressin enhances pHi regulation in the presence of HCO3\u2212 by stimulating three acid-base transport systems","volume":"337","author":"Ganz","year":"1989","journal-title":"Nature"},{"key":"10.1016\/j.lfs.2005.11.030_bib17","doi-asserted-by":"crossref","first-page":"9002","DOI":"10.1016\/S0021-9258(19)84480-0","article-title":"Monoclonal antibodies against human erythrocyte band 3 protein. Localization of proteolytic cleavage sites and stilbene disulfonate-binding lysine residues","volume":"261","author":"Jennings","year":"1986","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.lfs.2005.11.030_bib18","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1172\/JCI113699","article-title":"Acidosis during early reperfusion prevents myocardial stunning in perfused ferret hearts","volume":"82","author":"Kitakaze","year":"1988","journal-title":"Journal of Clinical Investigation"},{"key":"10.1016\/j.lfs.2005.11.030_bib19","doi-asserted-by":"crossref","first-page":"2521","DOI":"10.1006\/jmcc.1995.0239","article-title":"Aldosterone modulates both the Na\/H antiport and Cl\/HCO3 exchanger in cultured neonatal rat cardiac cells","volume":"27","author":"Korichneva","year":"1995","journal-title":"Journal of Molecular and Cellular Cardiology"},{"key":"10.1016\/j.lfs.2005.11.030_bib20","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1161\/01.RES.68.1.269","article-title":"Endothelin and increased contractility in adult rat ventricular myocytes. Role of intracellular alkalosis induced by activation of the protein kinase C-dependent Na+\u2013H+ exchanger","volume":"681","author":"Kramer","year":"1991","journal-title":"Circulation Research"},{"key":"10.1016\/j.lfs.2005.11.030_bib21","doi-asserted-by":"crossref","first-page":"11448","DOI":"10.1016\/S0021-9258(18)98979-9","article-title":"Functional differences among nonerythroid anion exchangers expressed in a transfected human cell line","volume":"266","author":"Lee","year":"1991","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.lfs.2005.11.030_bib22","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1111\/j.1469-7793.1998.471bn.x","article-title":"Out-of-equilibrium pH transients in the guinea pig ventricular myocyte","volume":"509","author":"Leem","year":"1998","journal-title":"Journal of Physiology (London)"},{"key":"10.1016\/j.lfs.2005.11.030_bib23","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1111\/j.1469-7793.1999.0159z.x","article-title":"Characterization of intracellular pH regulation in the guinea-pig ventricular myocyte","volume":"517","author":"Leem","year":"1999","journal-title":"Journal of Physiology (London)"},{"key":"10.1016\/j.lfs.2005.11.030_bib24","doi-asserted-by":"crossref","first-page":"7927","DOI":"10.1016\/S0021-9258(18)42601-4","article-title":"The predicted translation product of a cardiac AE3 mRNA contains an N terminus distinct from that of the brain AE3 Cl\u2212\/HCO3\u2212 exchanger. Cloning of a cardiac AE3 cDNA, organization of the AE gene and identification of an alternative initiation site","volume":"267","author":"Linn","year":"1992","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.lfs.2005.11.030_bib25","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1161\/01.RES.76.4.584","article-title":"Conservation of an AE3 Cl\u2212\/HCO3\u2212 exchanger cardiac specific exon and promoter region and AE3 mRNA expression patterns in murine and human hearts","volume":"76","author":"Linn","year":"1995","journal-title":"Circulation Research"},{"key":"10.1016\/j.lfs.2005.11.030_bib26","doi-asserted-by":"crossref","first-page":"22985","DOI":"10.1074\/jbc.274.33.22985","article-title":"Protein kinase-mediated regulation of the Na+\/H+ exchanger in the rat myocardium by mitogen-activated protein kinase-dependent pathways","volume":"274","author":"Moor","year":"1999","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.lfs.2005.11.030_bib27","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1113\/jphysiol.1991.sp018875","article-title":"Extracellular MgATP activates the Cl\u2212\/HCO3\u2212 exchanger in single rat cardiac cells","volume":"444","author":"Puc\u00e8at","year":"1991","journal-title":"Journal of Physiology (London)"},{"key":"10.1016\/j.lfs.2005.11.030_bib28","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1242\/jcs.112.10.1519","article-title":"A spliced variant of AE1 gene encodes a truncated form of Band 3 in heart: the predominant anion exchanger in ventricular myocytes","volume":"112","author":"Richards","year":"1999","journal-title":"Journal of Cell Science"},{"key":"10.1016\/j.lfs.2005.11.030_bib29","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1007\/s00424-003-1180-2","article-title":"The SLC4 family of HCO3\u2212 transporters","volume":"447","author":"Romero","year":"2004","journal-title":"Pfl\u00fcgers Archiv European Journal of Physiology"},{"key":"10.1016\/j.lfs.2005.11.030_bib30","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1083\/jcb.121.1.37","article-title":"Functional activation of plasma membrane anion exchangers occurs in a pre-Golgi compartment","volume":"121","author":"Ruetz","year":"1993","journal-title":"Journal of Cell Biology"},{"key":"10.1016\/j.lfs.2005.11.030_bib31","doi-asserted-by":"crossref","first-page":"C316","DOI":"10.1152\/ajpcell.1992.262.2.C316","article-title":"Relationship between intracellular pH and tension development in resting ventricular muscle and myocytes","volume":"262","author":"Spitzer","year":"1992","journal-title":"American Journal of Physiology. Cell Physiology"},{"key":"10.1016\/j.lfs.2005.11.030_bib32","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1042\/0264-6021:3440221","article-title":"Transport activity of AE3 chloride\/bicarbonate anion-exchange proteins and their regulation by intracellular pH","volume":"344","author":"Sterling","year":"1999","journal-title":"Biochemical Journal"},{"key":"10.1016\/j.lfs.2005.11.030_bib33","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1139\/o02-152","article-title":"Bicarbonate transport proteins","volume":"80","author":"Sterling","year":"2002","journal-title":"Biochemistry and Cell Biology"},{"key":"10.1016\/j.lfs.2005.11.030_bib34","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1038\/337601a0","article-title":"Bicarbonate and pHi response","volume":"337","author":"Thomas","year":"1989","journal-title":"Nature"},{"key":"10.1016\/j.lfs.2005.11.030_bib35","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1113\/jphysiol.1986.sp016259","article-title":"An investigation of chloride-bicarbonate exchange in the sheep cardiac","volume":"379","author":"Vaughan-Jones","year":"1986","journal-title":"Purkinje fibre Journal of Physiology (London)"},{"key":"10.1016\/j.lfs.2005.11.030_bib36","doi-asserted-by":"crossref","first-page":"C207","DOI":"10.1152\/ajpcell.1989.257.2.C207","article-title":"Na+\/H+ exchange in isolated myocyte from adult rat heart","volume":"257","author":"Wallert","year":"1989","journal-title":"American Journal of Physiology. Cell Physiology"},{"key":"10.1016\/j.lfs.2005.11.030_bib37","first-page":"7838","article-title":"Three N-terminal variants of the AE2 Cl\u2212\/HCO3\u2212 exchanger are encoded by mRNAs transcribed from alternative promoters","volume":"271","author":"Wang","year":"1996","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.lfs.2005.11.030_bib38","doi-asserted-by":"crossref","first-page":"H85","DOI":"10.1152\/ajpheart.1994.267.1.H85","article-title":"Na+-independent Cl\u2212\/HCO3\u2212 exchanges mediates recovery of pHi from alkalosis in guinea pig ventricular myocytes","volume":"267","author":"Xu","year":"1994","journal-title":"American Journal of Physiology. Heart Physiology"},{"key":"10.1016\/j.lfs.2005.11.030_bib39","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1161\/01.RES.75.4.603","article-title":"Molecular cloning, expression, and chromosomal localization of two isoforms of the AE3 anion exchanger from human heart","volume":"75","author":"Yannoukakos","year":"1994","journal-title":"Circulation Research"},{"key":"10.1016\/j.lfs.2005.11.030_bib40","doi-asserted-by":"crossref","first-page":"3112","DOI":"10.1074\/jbc.M207797200","article-title":"Novel topology model in C-terminal region of the human plasma membrane anion exchanger, AE1","volume":"278","author":"Zhu","year":"2003","journal-title":"Journal of Biological Chemistry"}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320505012622?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320505012622?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,7,23]],"date-time":"2021-07-23T14:32:20Z","timestamp":1627050740000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0024320505012622"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,5]]},"references-count":40,"journal-issue":{"issue":"26","published-print":{"date-parts":[[2006,5]]}},"alternative-id":["S0024320505012622"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2005.11.030","relation":{},"ISSN":["0024-3205"],"issn-type":[{"value":"0024-3205","type":"print"}],"subject":[],"published":{"date-parts":[[2006,5]]}}}