{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T11:32:55Z","timestamp":1791113575341,"version":"4.1.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"26","license":[{"start":{"date-parts":[[2006,5,1]],"date-time":"2006-05-01T00:00:00Z","timestamp":1146441600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2006,5]]},"DOI":"10.1016\/j.lfs.2005.12.011","type":"journal-article","created":{"date-parts":[[2006,1,19]],"date-time":"2006-01-19T14:00:46Z","timestamp":1137679246000},"page":"3066-3073","source":"Crossref","is-referenced-by-count":28,"title":["Regulation of cardiac and renal mineralocorticoid receptor expression by captopril following myocardial infarction in rats"],"prefix":"10.1016","volume":"78","author":[{"given":"Micheline Monteiro","family":"de Resende","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katalin","family":"Kauser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Geraldo","family":"Mill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.lfs.2005.12.011_bib1","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1016\/S0002-9149(99)80353-1","article-title":"Effects of adding spironolactone to an angiotensin-converting enzyme inhibitor in chronic congestive heart failure secondary to coronary artery disease","volume":"76","author":"Barr","year":"1995","journal-title":"American Journal of Cardiology"},{"key":"10.1016\/j.lfs.2005.12.011_bib2","doi-asserted-by":"crossref","first-page":"2325","DOI":"10.1161\/01.CIR.102.19.2325","article-title":"Striking increase of natriuresis by low-dose spironolactone in congestive heart failure only in combination with ACE inhibition. Mechanistic evidence to support RALES","volume":"102","author":"Bauersachs","year":"2000","journal-title":"Circulation"},{"key":"10.1016\/j.lfs.2005.12.011_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0008-6363(00)00092-4","article-title":"Renin\u2013angiotensin\u2013aldosterone system and myocardial fibrosis","volume":"47","author":"Brilla","year":"2000","journal-title":"Cardiovascular Research"},{"key":"10.1016\/j.lfs.2005.12.011_bib5","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1006\/jmcc.1994.1098","article-title":"Collagen metabolism in cultured adult rat cardiac fibroblast: response to angiotensin II and aldosterone","volume":"26","author":"Brilla","year":"1994","journal-title":"Journal of Molecular Cell Cardiology"},{"issue":"suppl C","key":"10.1016\/j.lfs.2005.12.011_bib4","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1093\/eurheartj\/16.suppl_C.45","article-title":"Hormonal regulation of cardiac fibroblast function","volume":"16","author":"Brilla","year":"1995","journal-title":"European Heart Journal"},{"key":"10.1016\/j.lfs.2005.12.011_bib6","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1590\/S0100-879X1997000500018","article-title":"Increased angiotensin-converting enzyme activity in the left ventricle after infarction","volume":"30","author":"Busatto","year":"1997","journal-title":"Brazilian Journal of Medical and Biological Research"},{"key":"10.1016\/j.lfs.2005.12.011_bib7","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1056\/NEJM198409273111303","article-title":"Plasma norepinephrine as a guide to prognosis in patients with chronic heart failure","volume":"311","author":"Cohn","year":"1984","journal-title":"New England Journal of Medicine"},{"key":"10.1016\/j.lfs.2005.12.011_bib8","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1097\/00043798-199510000-00002","article-title":"Pathophysiological aspects of the renin\u2013angiotensin system in acute myocardial infarction","volume":"2","author":"Dargie","year":"1995","journal-title":"Journal of Cardiovascular Risk"},{"key":"10.1016\/j.lfs.2005.12.011_bib10","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0008-6363(99)00088-7","article-title":"Aldosterone and the heart: towards a physiological function?","volume":"43","author":"Delcayre","year":"1999","journal-title":"Cardiovascular Research"},{"key":"10.1016\/j.lfs.2005.12.011_bib9","doi-asserted-by":"crossref","first-page":"1346","DOI":"10.1046\/j.1523-1755.2000.00973.x","article-title":"Cardiac aldosterone production and ventricular remodeling","volume":"57","author":"Delcayre","year":"2000","journal-title":"Kidney International"},{"key":"10.1016\/j.lfs.2005.12.011_bib11","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1097\/00043798-199510000-00006","article-title":"Effects of ACE inhibitors on mortality when started in the early phase of myocardial infarction: evidence from the larger randomized trials","volume":"2","author":"Flather","year":"1995","journal-title":"Journal of Cardiovascular Risk"},{"key":"10.1016\/j.lfs.2005.12.011_bib12","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1161\/01.RES.49.3.618","article-title":"Left ventricular diastolic pressure\u2013volume relations in rats with healed myocardial infarction. Effects on systolic function","volume":"49","author":"Fletcher","year":"1981","journal-title":"Circulation Research"},{"issue":"suppl 3","key":"10.1016\/j.lfs.2005.12.011_bib13","first-page":"S13","article-title":"A sensitive fluorimetric assay for angiotensin converting enzyme","volume":"6","author":"Friedland","year":"1976","journal-title":"Journal of Hypertension"},{"key":"10.1016\/j.lfs.2005.12.011_bib14","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1038\/sj.bjp.0704814","article-title":"Renal targeting of captopril selectively enhances the intrarenal over the systemic effects of ACE inhibition in rats","volume":"136","author":"Haverdings","year":"2002","journal-title":"British Journal of Pharmacology"},{"key":"10.1016\/j.lfs.2005.12.011_bib15","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1159\/000168356","article-title":"Aldosterone in congestive heart failure: analysis of determinants and role in sodium retention","volume":"11","author":"Hensen","year":"1991","journal-title":"American Journal of Nephrology"},{"key":"10.1016\/j.lfs.2005.12.011_bib16","first-page":"79","article-title":"Changes in collagen content in the residual myocardium surviving after infarction in rats. Influence of propranolol or hydralazine therapy","volume":"26","author":"Leite","year":"1995","journal-title":"Archives of Medical Research"},{"key":"10.1016\/j.lfs.2005.12.011_bib17","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1161\/01.RES.71.3.503","article-title":"Immunohistochemical and biochemical evidence for a cardiovascular endothelial and mineralocorticoid receptor","volume":"71","author":"Lombe","year":"1992","journal-title":"Circulation Research"},{"key":"10.1016\/j.lfs.2005.12.011_bib18","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","article-title":"Protein measurement with the Folin\u2013Phenol reagents","volume":"193","author":"Lowry","year":"1951","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.lfs.2005.12.011_bib19","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/S0008-6363(97)00091-6","article-title":"Aldosterone blockade reduces vascular collagen turnover, improves heart rate variability and reduces early morning rise in heart rate in heart failure patients","volume":"35","author":"MacFadyen","year":"1997","journal-title":"Cardiovascular Research"},{"key":"10.1016\/j.lfs.2005.12.011_bib20","doi-asserted-by":"crossref","first-page":"112","DOI":"10.2169\/internalmedicine.37.112","article-title":"The treatment of heart failure: the role of neurohumoral activation","volume":"37","author":"Middlekauff","year":"1998","journal-title":"Internal Medicine"},{"key":"10.1016\/j.lfs.2005.12.011_bib21","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S1071-9164(97)90015-4","article-title":"Effects of captopril on interstitial collagen in the myocardium after infarction in rats","volume":"3","author":"Milanez","year":"1997","journal-title":"Journal of Cardiac Failure"},{"key":"10.1016\/j.lfs.2005.12.011_bib22","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1046\/j.1440-1681.2003.03906.x","article-title":"Spironolactone prevents cardiac collagen proliferation after myocardial infarction in rats","volume":"30","author":"Mill","year":"2003","journal-title":"Clinical and Experimental Pharmacology and Physiology"},{"key":"10.1016\/j.lfs.2005.12.011_bib23","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1093\/cvr\/24.9.748","article-title":"Changes in performance of the surviving myocardium after left ventricular infarction in rats","volume":"24","author":"Mill","year":"1990","journal-title":"Cardiovascular Research"},{"key":"10.1016\/j.lfs.2005.12.011_bib24","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1161\/01.CIR.103.1.72","article-title":"Aldosterone production is activated in failing ventricle in humans","volume":"103","author":"Mizumo","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.lfs.2005.12.011_bib25","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.1161\/01.CIR.81.4.1161","article-title":"Ventricular remodeling after myocardial infarction. Experimental observations and clinical implications","volume":"81","author":"Pfeffer","year":"1990","journal-title":"Circulation"},{"key":"10.1016\/j.lfs.2005.12.011_bib26","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1161\/01.CIR.72.2.406","article-title":"Survival after an experimental myocardial infarction: beneficial effects of long-term therapy with captopril","volume":"72","author":"Pfeffer","year":"1985","journal-title":"Circulation"},{"key":"10.1016\/j.lfs.2005.12.011_bib28","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1056\/NEJM199909023411001","article-title":"The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators","volume":"341","author":"Pitt","year":"1999","journal-title":"New England Journal of Medicine"},{"key":"10.1016\/j.lfs.2005.12.011_bib27","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1056\/NEJMoa030207","article-title":"Eplerenone, a selective aldosterone blocker in patients with left ventricular dysfunction after myocardial infarction","volume":"348","author":"Pitt","year":"2003","journal-title":"New England Journal of Medicine"},{"key":"10.1016\/j.lfs.2005.12.011_bib29","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1161\/01.HYP.33.4.981","article-title":"Angiotensin AT1 receptor subtype as a cardiac target of aldosterone: role in aldosterone-salt-induced fibrosis","volume":"33","author":"Robert","year":"1999","journal-title":"Hypertension"},{"issue":"suppl I","key":"10.1016\/j.lfs.2005.12.011_bib30","doi-asserted-by":"crossref","first-page":"I121","DOI":"10.1161\/01.HYP.15.2_Suppl.I121","article-title":"The renin\u2013angiotensin system during acute myocardial ischemia in dogs","volume":"15","author":"Santos","year":"1990","journal-title":"Hypertension"},{"key":"10.1016\/j.lfs.2005.12.011_bib32","doi-asserted-by":"crossref","first-page":"4883","DOI":"10.1074\/jbc.273.9.4883","article-title":"Myocardial production of aldosterone and corticosterone in the rat. Physiological regulation","volume":"273","author":"Silvestre","year":"1998","journal-title":"Journal of Biological Chemistry"},{"key":"10.1016\/j.lfs.2005.12.011_bib31","doi-asserted-by":"crossref","first-page":"2694","DOI":"10.1161\/01.CIR.99.20.2694","article-title":"Activation of the cardiac aldosterone production in rat myocardial infarction: effect of angiotensin II receptor blockade and role in cardiac fibrosis","volume":"99","author":"Silvestre","year":"1999","journal-title":"Circulation"},{"key":"10.1016\/j.lfs.2005.12.011_bib33","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1152\/physrev.1999.79.1.215","article-title":"Molecular mechanisms of myocardial remodeling","volume":"79","author":"Swynghedauw","year":"1999","journal-title":"Physiological Reviews"},{"key":"10.1016\/j.lfs.2005.12.011_bib34","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1161\/01.RES.66.4.883","article-title":"Angiotensin II-forming pathways in normal and failing human hearts","volume":"66","author":"Urata","year":"1990","journal-title":"Circulation Research"},{"key":"10.1016\/j.lfs.2005.12.011_bib35","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1056\/NEJM199909023411009","article-title":"Aldosterone and spironolactone in heart failure","volume":"341","author":"Weber","year":"1999","journal-title":"New England Journal of Medicine"},{"key":"10.1016\/j.lfs.2005.12.011_bib36","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1067\/mhj.2001.119612","article-title":"Changes in vasoconstrictive hormones, natriuretic peptides, and left ventricular remodeling soon after anterior myocardial infarction","volume":"142","author":"White","year":"2001","journal-title":"American Heart Journal"},{"issue":"3A","key":"10.1016\/j.lfs.2005.12.011_bib37","doi-asserted-by":"crossref","first-page":"158A","DOI":"10.1016\/S0002-9149(97)00473-6","article-title":"The kallicrein\u2013kinin system in post-myocardial infarction cardiac remodeling","volume":"80","author":"Wollert","year":"1997","journal-title":"American Journal of Cardiology"}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320505012476?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320505012476?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,7,22]],"date-time":"2021-07-22T17:12:35Z","timestamp":1626973955000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0024320505012476"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,5]]},"references-count":37,"journal-issue":{"issue":"26","published-print":{"date-parts":[[2006,5]]}},"alternative-id":["S0024320505012476"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2005.12.011","relation":{},"ISSN":["0024-3205"],"issn-type":[{"value":"0024-3205","type":"print"}],"subject":[],"published":{"date-parts":[[2006,5]]}}}