{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T12:52:08Z","timestamp":1761310328230},"reference-count":16,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2006,8,1]],"date-time":"2006-08-01T00:00:00Z","timestamp":1154390400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2006,8]]},"DOI":"10.1016\/j.lfs.2006.03.005","type":"journal-article","created":{"date-parts":[[2006,4,20]],"date-time":"2006-04-20T08:05:47Z","timestamp":1145520347000},"page":"1034-1039","source":"Crossref","is-referenced-by-count":5,"title":["Cytoprotective effect of two synthetic enhancer substances, (\u2212)-BPAP and (\u2212)-deprenyl, on human brain capillary endothelial cells and rat PC12 cells"],"prefix":"10.1016","volume":"79","author":[{"given":"Laszlo","family":"Denes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00e9za","family":"Szil\u00e1gyi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anik\u00f3","family":"G\u00e1l","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zolt\u00e1n","family":"Bori","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zolt\u00e1n","family":"Nagy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.lfs.2006.03.005_bib1","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1023\/A:1007050808754","article-title":"(\u2212)-1-(Benzofuran-2-yl)-2-propylaminopentane shows survival effect on cortical neurons under serum-free condition through sigma receptor","volume":"20","author":"Hamabe","year":"2000","journal-title":"Cellular and Molecular Neurobiology"},{"issue":"2","key":"10.1016\/j.lfs.2006.03.005_bib2","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1111\/j.1600-0773.1994.tb00326.x","article-title":"Memories of my 45 years in research","volume":"75","author":"Knoll","year":"1994","journal-title":"Pharmacology and Toxicology"},{"issue":"8","key":"10.1016\/j.lfs.2006.03.005_bib3","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1023\/A:1024224311289","article-title":"Enhancer regulation\/endogenous and synthetic enhancer compounds: a neurochemical concept of the innate and acquired drives","volume":"28","author":"Knoll","year":"2003","journal-title":"Neurochemical Research"},{"key":"10.1016\/j.lfs.2006.03.005_bib4","series-title":"The Brain and Its Self. A Neurochemical Concept of the Innate and Acquired Drives","first-page":"1","author":"Knoll","year":"2005"},{"key":"10.1016\/j.lfs.2006.03.005_bib5","first-page":"393","article-title":"Some puzzling pharmacological effects of monoamine oxidase inhibitors","volume":"5","author":"Knoll","year":"1972","journal-title":"Advances in Biochemistry and Psychopharmacology"},{"issue":"8","key":"10.1016\/j.lfs.2006.03.005_bib6","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1038\/sj.bjp.0702995","article-title":"(\u2212)-1-(Benzfuran-2yl)-2-propylaminopentane, [(\u2212)-BPAP], a selective enhancer of the impulse propagation mediated release of catecholamine and serotonin in the brain","volume":"128","author":"Knoll","year":"1999","journal-title":"British Journal of Pharmacology"},{"issue":"18","key":"10.1016\/j.lfs.2006.03.005_bib7","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.1016\/S0024-3205(02)01969-0","article-title":"Stimulation of the catecholaminergic and serotonergic neurons in the rat brain by R-(\u2212)-1-(benzofuran-2-yl)-2-propylaminopentane, (\u2212)-BPAP","volume":"71","author":"Knoll","year":"2002","journal-title":"Life Sciences"},{"issue":"1","key":"10.1016\/j.lfs.2006.03.005_bib8","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/0014-4827(87)90243-6","article-title":"Restimulation of cell cycle progression by hypoxic tumour cells with deoxynucleosides requires ppm oxygen tension","volume":"169","author":"L\u00f6ffler","year":"1987","journal-title":"Experimental Cell Research"},{"issue":"1\u20132","key":"10.1016\/j.lfs.2006.03.005_bib9","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0161-813X(03)00102-5","article-title":"(\u2212)-Deprenyl, a selective MAO-B inhibitor, with apoptotic and anti-apoptotic properties","volume":"25","author":"Magyar","year":"2004","journal-title":"Neurotoxicology"},{"issue":"1","key":"10.1016\/j.lfs.2006.03.005_bib10","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.lfs.2003.12.001","article-title":"Neuroprotective function of R-(\u2212)-1-(benzofuran-2-yl)-2-propylaminopentane, [R-(\u2212)-BPAP], against apoptosis induced by N-methyl(R) salsolinol, an endogenous dopaminergic neurotoxin, in human dopaminergic neuroblastoma SH-SY5Y cells","volume":"75","author":"Maruyama","year":"2004","journal-title":"Life Sciences"},{"issue":"3","key":"10.1016\/j.lfs.2006.03.005_bib11","doi-asserted-by":"crossref","first-page":"200","DOI":"10.2302\/kjm.45.200","article-title":"Human brain microvessel endothelial cell culture as a model system to study vascular factors of ischemic brain","volume":"45","author":"Nagy","year":"1996","journal-title":"Keio Journal of Medicine"},{"issue":"3","key":"10.1016\/j.lfs.2006.03.005_bib12","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/S0304-3940(02)00461-5","article-title":"Novel catecholaminergic and serotonergic activity enhancer R-(\u2212)-1-(benzofuran-2-yl)-2-propylaminopentane up-regulates neurotic factor synthesis in mouse astrocytes","volume":"328","author":"Ohta","year":"2002","journal-title":"Neuroscience Letter"},{"key":"10.1016\/j.lfs.2006.03.005_bib13","series-title":"Physiology and Surgical Implications","first-page":"4","article-title":"Vasoactive factors produced by the endothelium","author":"Seccombe","year":"1994"},{"issue":"24","key":"10.1016\/j.lfs.2006.03.005_bib14","doi-asserted-by":"crossref","first-page":"2785","DOI":"10.1016\/S0024-3205(03)00191-7","article-title":"Enhancer substances: Selegiline and R-(\u2212)-1-(benzofuran-2-yl)-2-propylaminopentane [(\u2212)-BPAP] enhance the neurotrophic factor synthesis on cultured mouse astrocytes","volume":"72","author":"Shimazu","year":"2003","journal-title":"Life Sciences"},{"issue":"2\u20133","key":"10.1016\/j.lfs.2006.03.005_bib15","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/S0014-2999(01)01375-9","article-title":"(\u2212)-Deprenyl attenuates apoptosis in experimental brain ischemia","volume":"430","author":"Simon","year":"2001","journal-title":"European Journal of Pharmacology"},{"issue":"4","key":"10.1016\/j.lfs.2006.03.005_bib16","doi-asserted-by":"crossref","first-page":"1572","DOI":"10.1046\/j.1471-4159.1994.63041572.x","article-title":"(\u2212)-Deprenyl reduces PC12 cell apoptosis by inducing new protein synthesis","volume":"63","author":"Tatton","year":"1994","journal-title":"Journal of Neurochemistry"}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320506002219?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320506002219?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,16]],"date-time":"2019-01-16T20:59:00Z","timestamp":1547672340000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0024320506002219"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,8]]},"references-count":16,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2006,8]]}},"alternative-id":["S0024320506002219"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2006.03.005","relation":{},"ISSN":["0024-3205"],"issn-type":[{"value":"0024-3205","type":"print"}],"subject":[],"published":{"date-parts":[[2006,8]]}}}