{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T19:34:45Z","timestamp":1769628885806,"version":"3.49.0"},"reference-count":24,"publisher":"Elsevier BV","issue":"24-25","license":[{"start":{"date-parts":[[2007,5,1]],"date-time":"2007-05-01T00:00:00Z","timestamp":1177977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2007,5]]},"DOI":"10.1016\/j.lfs.2007.01.028","type":"journal-article","created":{"date-parts":[[2007,1,26]],"date-time":"2007-01-26T17:43:38Z","timestamp":1169833418000},"page":"2221-2226","source":"Crossref","is-referenced-by-count":55,"title":["Hydrogen peroxide regulates the cholinergic signal in a concentration dependent manner"],"prefix":"10.1016","volume":"80","author":[{"given":"Karin U.","family":"Schallreuter","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Souna","family":"Elwary","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2-3","key":"10.1016\/j.lfs.2007.01.028_bb0005","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.mrrev.2003.06.016","article-title":"Oestrogenic compounds and oxidative stress (in human sperm and lymphocytes in the Comet assay)","volume":"544","author":"Anderson","year":"2003","journal-title":"Mutation Research"},{"issue":"692","key":"10.1016\/j.lfs.2007.01.028_bb0010","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1126\/science.150.3692.72","article-title":"Catalase: kinetics of photooxidation","volume":"150","author":"Aronoff","year":"1965","journal-title":"Science"},{"issue":"5","key":"10.1016\/j.lfs.2007.01.028_bb0015","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1093\/hmg\/7.5.933","article-title":"Analysis of the butyrylcholinesterase gene and nearby chromosome 3 markers in Alzheimer disease","volume":"7","author":"Brindle","year":"1998","journal-title":"Human Molecular Genetics"},{"issue":"Suppl 3","key":"10.1016\/j.lfs.2007.01.028_bb0020","first-page":"403","article-title":"Functional and structural index of cellular impairment during vitiligo","volume":"126","author":"Dell'Anna","year":"2006","journal-title":"Journal of Investigative Dermatology"},{"issue":"1","key":"10.1016\/j.lfs.2007.01.028_bb0025","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1111\/j.1365-2133.1997.tb03704.x","article-title":"Calcium homeostasis influences epidermal sweating in patients with vitiligo","volume":"137","author":"Elwary","year":"1997","journal-title":"British Journal of Dermatology"},{"issue":"8","key":"10.1016\/j.lfs.2007.01.028_bb0030","doi-asserted-by":"crossref","first-page":"1879","DOI":"10.1038\/sj.jid.5700268","article-title":"The vesicular acetylcholine transporter is present in melanocytes and keratinocytes in the human epidermis","volume":"126","author":"Elwary","year":"2006","journal-title":"Journal of Investigative Dermatology"},{"key":"10.1016\/j.lfs.2007.01.028_bb0035","series-title":"Enzyme Structure and Mechanism","author":"Fersht","year":"1985"},{"issue":"12","key":"10.1016\/j.lfs.2007.01.028_bb0040","doi-asserted-by":"crossref","first-page":"2576","DOI":"10.1038\/sj.jid.5700612","article-title":"Computer simulation of native epidermal enzyme structures in the presence and absence of hydrogen peroxide (H2O2): potential and pitfalls","volume":"126","author":"Gibbons","year":"2006","journal-title":"Journal of Investigative Dermatology"},{"issue":"9","key":"10.1016\/j.lfs.2007.01.028_bb0045","doi-asserted-by":"crossref","first-page":"1948","DOI":"10.1038\/sj.jid.5700151","article-title":"Adrenergic and cholinergic control in the biology of epidermis: physiological and clinical significance","volume":"126","author":"Grando","year":"2006","journal-title":"Journal of Investigative Dermatology"},{"issue":"2","key":"10.1016\/j.lfs.2007.01.028_bb0050","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1046\/j.0022-202X.2004.22230.x","article-title":"Perturbed 6-tetrahydrobiopterin recycling via decreased dihydropteridine reductase in vitiligo: more evidence for H2O2 stress","volume":"122","author":"Hasse","year":"2004","journal-title":"Journal of Investigative Dermatology"},{"issue":"2","key":"10.1016\/j.lfs.2007.01.028_bb0055","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1159\/000146813","article-title":"Modulation of melanocytic activity by acetylcholine","volume":"136","author":"Iyengar","year":"1989","journal-title":"Acta Anatomica"},{"issue":"3","key":"10.1016\/j.lfs.2007.01.028_bb0060","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1111\/1523-1747.ep12335801","article-title":"Increased sensitivity to peroxidative agents as a possible pathogenic factor of melanocyte damage in vitiligo","volume":"109","author":"Maresca","year":"1997","journal-title":"Journal of Investigative Dermatology"},{"issue":"1","key":"10.1016\/j.lfs.2007.01.028_bb0065","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1038\/sj.jid.5700021","article-title":"UVA-induced modification of catalase charge properties in the epidermis is correlated with the skin phototype","volume":"126","author":"Maresca","year":"2006","journal-title":"Journal of Investigative Dermatology"},{"issue":"42","key":"10.1016\/j.lfs.2007.01.028_bb0070","doi-asserted-by":"crossref","first-page":"41141","DOI":"10.1074\/jbc.M210241200","article-title":"Crystal structure of human butyrylcholinesterase and of its complexes with substrate and products","volume":"278","author":"Nicolet","year":"2003","journal-title":"Journal of Biological Chemistry"},{"issue":"5782","key":"10.1016\/j.lfs.2007.01.028_bb0075","doi-asserted-by":"crossref","first-page":"1882","DOI":"10.1126\/science.1130481","article-title":"Cell signaling. H2O2, a necessary evil for cell signaling","volume":"312","author":"Rhee","year":"2006","journal-title":"Science"},{"issue":"5","key":"10.1016\/j.lfs.2007.01.028_bb0080","first-page":"505","article-title":"Oxidative stress in the human epidermis","volume":"140","author":"Schallreuter","year":"2005","journal-title":"Giornale Italiano Dermatologia Venereologia"},{"key":"10.1016\/j.lfs.2007.01.028_bb0085","series-title":"Autoimmune Diseases of the Skin. Pathogenesis, Diagnosis, Management","first-page":"367","article-title":"Vitiligo","author":"Schallreuter","year":"2005"},{"issue":"1","key":"10.1016\/j.lfs.2007.01.028_bb0090","doi-asserted-by":"crossref","first-page":"57","DOI":"10.4103\/0378-6323.19722","article-title":"Turmeric (curcumin): a widely used curry ingredient, can contribute to oxidative stress in Asian patients with acute vitiligo","volume":"72","author":"Schallreuter","year":"2006","journal-title":"Indian Journal of Dermatology, Venereology and Leprology"},{"issue":"6","key":"10.1016\/j.lfs.2007.01.028_bb0095","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1111\/1523-1747.ep12492612","article-title":"Low catalase levels in the epidermis of patients with vitiligo","volume":"97","author":"Schallreuter","year":"1991","journal-title":"Journal of Investigative Dermatology"},{"issue":"1","key":"10.1016\/j.lfs.2007.01.028_bb0100","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1038\/sj.jidsp.5640189","article-title":"In vivo and in vitro evidence for hydrogen peroxide (H2O2) accumulation in the epidermis of patients with vitiligo and its successful removal by a UVB-activated pseudocatalase","volume":"4","author":"Schallreuter","year":"1999","journal-title":"Journal of Investigative Dermatology Symposium Proceedings"},{"issue":"1","key":"10.1016\/j.lfs.2007.01.028_bb0105","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1046\/j.1523-1747.2001.00220.x","article-title":"Epidermal H2O2 accumulation alters tetrahydrobiopterin (6BH4) recycling in vitiligo: identification of a general mechanism in regulation of all 6BH4-dependent processes?","volume":"116","author":"Schallreuter","year":"2001","journal-title":"Journal of Investigative Dermatology"},{"issue":"2","key":"10.1016\/j.lfs.2007.01.028_bb0110","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.bbrc.2004.01.082","article-title":"Activation\/deactivation of acetylcholinesterase by H2O2: more evidence for oxidative stress in vitiligo","volume":"315","author":"Schallreuter","year":"2004","journal-title":"Biochemical and Biophysical Research Communication"},{"issue":"3","key":"10.1016\/j.lfs.2007.01.028_bb0115","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1016\/j.bbrc.2006.08.138","article-title":"Butyrylcholinesterase is present in the human epidermis and is regulated by H2O2: more evidence for oxidative stress in vitiligo","volume":"349","author":"Schallreuter","year":"2006","journal-title":"Biochemical and Biophysical Research Communication"},{"issue":"5","key":"10.1016\/j.lfs.2007.01.028_bb0120","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1038\/sj.jid.5700257","article-title":"Estrogens can contribute to hydrogen peroxide generation and quinone-mediated DNA damage in peripheral blood lymphocytes from patients with vitiligo","volume":"126","author":"Schallreuter","year":"2006","journal-title":"Journal of Investigative Dermatology"}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002432050700077X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002432050700077X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,9]],"date-time":"2019-01-09T16:59:40Z","timestamp":1547053180000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002432050700077X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5]]},"references-count":24,"journal-issue":{"issue":"24-25","published-print":{"date-parts":[[2007,5]]}},"alternative-id":["S002432050700077X"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2007.01.028","relation":{},"ISSN":["0024-3205"],"issn-type":[{"value":"0024-3205","type":"print"}],"subject":[],"published":{"date-parts":[[2007,5]]}}}