{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T12:10:40Z","timestamp":1783426240263,"version":"3.54.6"},"reference-count":26,"publisher":"Elsevier BV","issue":"9-10","license":[{"start":{"date-parts":[[2009,2,1]],"date-time":"2009-02-01T00:00:00Z","timestamp":1233446400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2009,2]]},"DOI":"10.1016\/j.lfs.2008.12.009","type":"journal-article","created":{"date-parts":[[2008,12,17]],"date-time":"2008-12-17T12:23:27Z","timestamp":1229516607000},"page":"278-281","source":"Crossref","is-referenced-by-count":5,"title":["Prostaglandin involvement in hyperthermia induced by sleep deprivation: A pharmacological and autoradiographic study"],"prefix":"10.1016","volume":"84","author":[{"given":"B.D.","family":"Palma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.N.","family":"Nobrega","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.L.","family":"Gomes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.A.","family":"Esumi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.L.V.","family":"Seabra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Tufik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.C.","family":"Hipolide","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.lfs.2008.12.009_bib1","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1093\/sleep\/12.1.31","article-title":"Sleep deprivation in the rat: V. Energy use and mediation","volume":"12","author":"Bergmann","year":"1989","journal-title":"Sleep"},{"key":"10.1016\/j.lfs.2008.12.009_bib2","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1093\/sleep\/16.3.221","article-title":"Sleep deprivation in the rat: XVII. Effect of aspirin on elevated body temperature","volume":"16","author":"Bergmann","year":"1993","journal-title":"Sleep"},{"key":"10.1016\/j.lfs.2008.12.009_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.prostaglandins.2005.01.001","article-title":"Cytokines, PGE2 and endotoxic fever: a re-assessment","volume":"76","author":"Blatteis","year":"2005","journal-title":"Prostaglandins and Other Lipid Mediators"},{"key":"10.1016\/j.lfs.2008.12.009_bib4","first-page":"113","article-title":"Inhibitors of cyclooxygenases: mechanisms, selectivity and uses","volume":"57","author":"Botting","year":"2006","journal-title":"Journal of Physiology and Pharmacology"},{"key":"10.1016\/j.lfs.2008.12.009_bib5","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/BF02918594","article-title":"Interleukin 1 as mediator of the acute-phase response","volume":"3","author":"Dinarello","year":"1984","journal-title":"Survey of Immunologic Research"},{"key":"10.1016\/j.lfs.2008.12.009_bib6","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.plefa.2005.05.021","article-title":"Effect of rapid-eye-movement sleep deprivation on rat hypothalamic prostaglandins","volume":"73","author":"Gelir","year":"2005","journal-title":"Prostaglandins, Leukotrienes and Essential Fatty Acids"},{"key":"10.1016\/j.lfs.2008.12.009_bib7","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/0960-5428(95)00010-Y","article-title":"Prostaglandins and sleep","volume":"5","author":"Hayaishi","year":"1995","journal-title":"Advances in Neuroimmunology"},{"key":"10.1016\/j.lfs.2008.12.009_bib8","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1016\/j.bbi.2003.03.001","article-title":"Sleep-deprived mice show altered cytokine production manifest by perturbations in serum IL-1ra, TNFa, and IL-6 levels","volume":"17","author":"Hu","year":"2003","journal-title":"Brain Behavior and Immunity"},{"key":"10.1016\/j.lfs.2008.12.009_bib9","first-page":"756","article-title":"Study of selective deprivation of the paradoxal sleep phase in the cat","volume":"158","author":"Jouvet","year":"1964","journal-title":"Comptes rendus des s\u00e9ances de la Soci\u00e9t\u00e9 de biologie et de ses filiales"},{"key":"10.1016\/j.lfs.2008.12.009_bib10","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1002\/mnfr.200500207","article-title":"The differential role of prostaglandin E2 receptors EP3 and EP4 in regulation of fever","volume":"50","author":"Lazarus","year":"2006","journal-title":"Molecular Nutrition and Food Research"},{"key":"10.1016\/j.lfs.2008.12.009_bib11","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.brainres.2004.01.019","article-title":"Sleep deprivation induced by the modified multiple platform technique: quantification of sleep loss and recovery","volume":"1004","author":"Machado","year":"2004","journal-title":"Brain Research"},{"key":"10.1016\/j.lfs.2008.12.009_bib12","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/0006-8993(89)90800-7","article-title":"Awaking effect of prostaglandin E 2 in freely moving rats","volume":"481","author":"Matsumura","year":"1989","journal-title":"Brain Research"},{"key":"10.1016\/j.lfs.2008.12.009_bib13","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/0006-8993(92)90720-T","article-title":"Mapping of prostaglandin E2 binding sites in rat brain using quantitative autoradiography","volume":"581","author":"Matsumura","year":"1992","journal-title":"Brain Research"},{"key":"10.1016\/j.lfs.2008.12.009_bib14","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/0166-2236(90)90081-K","article-title":"Keeping cool: a hypothesis about the mechanisms and functions of slow-wave sleep","volume":"13","author":"McGinty","year":"1990","journal-title":"Trends in Neuroscience"},{"key":"10.1016\/j.lfs.2008.12.009_bib15","series-title":"Pyretics and Antipyretics","first-page":"259","article-title":"Prostaglandins in fever and the mode of action of antipyretic drugs","author":"Milton","year":"1982"},{"key":"10.1016\/j.lfs.2008.12.009_bib16","first-page":"S26","article-title":"Variations of hypothalamic and cortical prostaglandins and monoamines reveal transitions in arousal states: microdialysis study in the rat","volume":"157","author":"Nicolaidis","year":"2001","journal-title":"Revue Neurologique"},{"key":"10.1016\/j.lfs.2008.12.009_bib17","doi-asserted-by":"crossref","first-page":"2715","DOI":"10.1523\/JNEUROSCI.12-07-02715.1992","article-title":"Prostaglandin E2 exerts an awaking effect in the posterior hypothalamus at a site distinct from that mediating its febrile action in the anterior hypothalamus","volume":"12","author":"Onoe","year":"1992","journal-title":"Journal of Neuroscience"},{"key":"10.1016\/j.lfs.2008.12.009_bib18","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0006-8993(94)91764-7","article-title":"Interleukin-1 is involved in responses to sleep deprivation in the rabbit","volume":"639","author":"Opp","year":"1994","journal-title":"Brain Research"},{"key":"10.1016\/j.lfs.2008.12.009_bib19","series-title":"The Rat Brain in Stereotaxic Coordinates","author":"Paxinos","year":"1997"},{"key":"10.1016\/j.lfs.2008.12.009_bib20","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1093\/sleep\/14.2.109","article-title":"Rechtschaffen. Sleep deprivation in the rat: XII. Effect on ambient temperature choice","volume":"14","author":"Prete","year":"1991","journal-title":"Sleep"},{"key":"10.1016\/j.lfs.2008.12.009_bib21","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0006-8993(96)01401-1","article-title":"CSF levels of prostaglandins, especially the level of prostaglandin D, are 2 correlated with increasing propensity towards sleep in rats","volume":"751","author":"Ram","year":"1997","journal-title":"Brain Research"},{"key":"10.1016\/j.lfs.2008.12.009_bib22","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/0031-9384(93)90303-W","article-title":"Sodium diclofenac inhibits hyperthermia induced by paradoxical sleep deprivation: the possible participation of prostaglandins","volume":"54","author":"Seabra","year":"1993","journal-title":"Physiology and Behavior"},{"key":"10.1016\/j.lfs.2008.12.009_bib23","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.psyneuen.2005.06.009","article-title":"Effects of sleep deprivation on cardiac autonomic and pituitary-adrenocortical stress reactivity in rats","volume":"31","author":"Sgoifo","year":"2006","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.lfs.2008.12.009_bib24","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1046\/j.1365-2869.1998.00122.x","article-title":"Increased ACTH and corticosterone secretion induced by different methods of paradoxical sleep deprivation","volume":"7","author":"Suchecki","year":"1998","journal-title":"Journal of Sleep Research"},{"key":"10.1016\/j.lfs.2008.12.009_bib25","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1089\/jir.1998.18.793","article-title":"Sleep-associated changes in interleukin-1beta mRNA in the brain","volume":"18","author":"Taishi","year":"1998","journal-title":"Journal of Interferon and Cytokine Research"},{"key":"10.1016\/j.lfs.2008.12.009_bib26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1471-4159.1982.tb10847.x","article-title":"Eicosanoids: prostaglandins, thromboxanes, leukotrienes, and other derivatives of carbon-20 unsaturated fatty acids","volume":"38","author":"Wolfe","year":"1982","journal-title":"Journal of Neurochemistry"}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002432050800502X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002432050800502X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,23]],"date-time":"2023-05-23T00:42:22Z","timestamp":1684802542000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002432050800502X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,2]]},"references-count":26,"journal-issue":{"issue":"9-10","published-print":{"date-parts":[[2009,2]]}},"alternative-id":["S002432050800502X"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2008.12.009","relation":{},"ISSN":["0024-3205"],"issn-type":[{"value":"0024-3205","type":"print"}],"subject":[],"published":{"date-parts":[[2009,2]]}}}