{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T12:31:12Z","timestamp":1790857872049,"version":"4.1.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"15-16","license":[{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"Chinese National Natural Science Foundation Project","doi-asserted-by":"crossref","award":["81072686"],"award-info":[{"award-number":["81072686"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"Chinese National Natural Science Foundation Project","doi-asserted-by":"crossref","award":["30873081"],"award-info":[{"award-number":["30873081"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"Chinese National Natural Science Foundation Project","doi-asserted-by":"crossref","award":["81102493"],"award-info":[{"award-number":["81102493"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100013286","name":"Specialized Research Fund for the Doctoral Program of Higher Education of China","doi-asserted-by":"crossref","award":["20103420120001"],"award-info":[{"award-number":["20103420120001"]}],"id":[{"id":"10.13039\/501100013286","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2012,4]]},"DOI":"10.1016\/j.lfs.2012.02.012","type":"journal-article","created":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T09:00:42Z","timestamp":1330592442000},"page":"612-618","source":"Crossref","is-referenced-by-count":30,"title":["Inhibition of transient receptor potential melastain 7 channel increases HSCs apoptosis induced by TRAIL"],"prefix":"10.1016","volume":"90","author":[{"given":"Hong","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.lfs.2012.02.012_bb0005","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1111\/j.1365-2184.2007.00476.x","article-title":"Importance of melastatin-like transient receptor potential 7 and cations [magnesium, calcium] in human osteoblast-like cell proliferation","volume":"40","author":"Abed","year":"2007","journal-title":"Cell Prolif"},{"key":"10.1016\/j.lfs.2012.02.012_bb0010","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1152\/ajpcell.00614.2008","article-title":"Importance of melastatin-like transient receptor potential 7 and magnesium in the stimulation of osteoblast proliferation and migration by platelet-derived growth factor","volume":"297","author":"Abed","year":"2009","journal-title":"Am J Physiol Cell Physiol"},{"key":"10.1016\/j.lfs.2012.02.012_bb0015","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/978-94-007-0265-3_9","article-title":"TRPM7, the Mg(2+) inhibited channel and kinase","volume":"704","author":"Bates-Withers","year":"2011","journal-title":"Adv Exp Med Biol"},{"issue":"9","key":"10.1016\/j.lfs.2012.02.012_bb0020","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1089\/scd.2009.0262","article-title":"Transient receptor potential melastatin type 7 channel is critical for the survival of bone marrow derived mesenchymal stem cells","volume":"19","author":"Cheng","year":"2010","journal-title":"Stem Cells Dev"},{"key":"10.1016\/j.lfs.2012.02.012_bb0025","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1038\/sj.emboj.7600931","article-title":"TRPM7, a novel regulator of actomyosin contractility and cell adhesion","volume":"25","author":"Clark","year":"2006","journal-title":"EMBO J"},{"key":"10.1016\/j.lfs.2012.02.012_bb0030","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1016\/j.jmb.2008.02.057","article-title":"TRPM7 regulates myosin IIA filament stability and protein localization by heavy chain phosphorylation","volume":"378","author":"Clark","year":"2008","journal-title":"J Mol Biol"},{"key":"10.1016\/j.lfs.2012.02.012_bb0035","doi-asserted-by":"crossref","first-page":"1781","DOI":"10.1002\/hep.24276","article-title":"Methods and interest of noninvasive assessment of liver fibrosis are still in debate","volume":"53","author":"Degos","year":"2011","journal-title":"Hepatology"},{"key":"10.1016\/j.lfs.2012.02.012_bb0040","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1161\/CIRCRESAHA.109.206771","article-title":"TRPM7-mediated Ca2+ signals confer fibrogenesis in human atrial fibrillation","volume":"106","author":"Du","year":"2010","journal-title":"Circ Res"},{"issue":"5","key":"10.1016\/j.lfs.2012.02.012_bb0045","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1152\/ajpgi.00451.2010","article-title":"Therapeutic targets in liver fibrosis","volume":"300","author":"Fallowfield","year":"2011","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1016\/j.lfs.2012.02.012_bb0050","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1152\/ajpcell.00624.2008","article-title":"Evidence that TRPM7 is required for breast cancer cell proliferation","volume":"297","author":"Guilbert","year":"2009","journal-title":"Am J Physiol Cell Physiol"},{"key":"10.1016\/j.lfs.2012.02.012_bb0055","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1254\/jphs.FP0040273","article-title":"Involvement of TRPM7 in cell growth as a spontaneously activated Ca2+ entry pathway in human retinoblastoma cells","volume":"95","author":"Hanano","year":"2004","journal-title":"J Pharmacol Sci"},{"key":"10.1016\/j.lfs.2012.02.012_bb0060","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.ejphar.2009.06.066","article-title":"TNF-related apoptosis-inducing ligand [TRAIL]: a new path to anti-cancer therapies","volume":"625","author":"Holoch","year":"2009","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.lfs.2012.02.012_bb0065","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1161\/01.RES.0000233356.10630.8a","article-title":"Transient receptor potential channels in cardiovascular function and disease","volume":"99","author":"Inoue","year":"2006","journal-title":"Circ Res"},{"key":"10.1016\/j.lfs.2012.02.012_bb0070","doi-asserted-by":"crossref","first-page":"10929","DOI":"10.1158\/0008-5472.CAN-07-1121","article-title":"Transient receptor potential melastatin 7-like current in human head and neck carcinoma cells: role in cell proliferation","volume":"67","author":"Jiang","year":"2007","journal-title":"Cancer Res"},{"issue":"5","key":"10.1016\/j.lfs.2012.02.012_bb0075","doi-asserted-by":"crossref","first-page":"E225","DOI":"10.1073\/pnas.1120033109","article-title":"The channel kinase, TRPM7, is required for early embryonic development","volume":"109","author":"Jin","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.lfs.2012.02.012_bb0080","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1038\/nrc2465","article-title":"The TRAIL apoptotic pathway in cancer onset, progression and therapy","volume":"8","author":"Johnstone","year":"2008","journal-title":"Nat Rev Cancer"},{"issue":"3","key":"10.1016\/j.lfs.2012.02.012_bb0085","first-page":"48","article-title":"TRP channels as novel cellular sensors","volume":"102","author":"Karashima","year":"2011","journal-title":"Fukuoka Igaku Zasshi"},{"key":"10.1016\/j.lfs.2012.02.012_bb0090","doi-asserted-by":"crossref","first-page":"2502","DOI":"10.1111\/j.1349-7006.2008.00982.x","article-title":"Suppression of transient receptor potential melastatin 7 channel induces cell death in gastric cancer","volume":"99","author":"Kim","year":"2008","journal-title":"Cancer Sci"},{"issue":"2","key":"10.1016\/j.lfs.2012.02.012_bb0095","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.bpg.2011.02.005","article-title":"Mechanisms of hepatic fibrogenesis","volume":"25","author":"Lee","year":"2011","journal-title":"Best Pract Res Clin Gastroenterol"},{"issue":"2","key":"10.1016\/j.lfs.2012.02.012_bb0100","first-page":"156","article-title":"Ion channels as targets for cancer therapy","volume":"3","author":"Li","year":"2011","journal-title":"Int J Physiol Pathophysiol Pharmacol."},{"key":"10.1016\/j.lfs.2012.02.012_bb0105","doi-asserted-by":"crossref","first-page":"1299","DOI":"10.1517\/14728222.11.10.1299","article-title":"TRAIL in cancer therapy: present and future challenges","volume":"11","author":"Merino","year":"2007","journal-title":"Expert Opin Ther Targets"},{"key":"10.1016\/j.lfs.2012.02.012_bb0110","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1085\/jgp.20028740","article-title":"TRPM7 provides an ion channel mechanism for cellular entry of trace metal ions","volume":"121","author":"Monteilh-Zoller","year":"2003","journal-title":"J Gen Physiol"},{"key":"10.1016\/j.lfs.2012.02.012_bb0115","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1038\/cdd.2010.144","article-title":"Chemotherapy overcomes TRAIL-R4-mediated TRAIL resistance at the DISC level","volume":"18","author":"Morizot","year":"2011","journal-title":"Cell Death Differ"},{"key":"10.1016\/j.lfs.2012.02.012_bb0120","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1161\/01.RES.0000200179.29375.cc","article-title":"Functional TRPM7 channels accumulate at the plasma membrane in response to fluid flow","volume":"98","author":"Oancea","year":"2006","journal-title":"Circ Res"},{"issue":"3","key":"10.1016\/j.lfs.2012.02.012_bb0125","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.mehy.2010.02.037","article-title":"Does a higher ratio of serum calcium to magnesium increase the risk for postmenopausal breast cancer?","volume":"75","author":"Sahmoun","year":"2010","journal-title":"Med Hypotheses"},{"key":"10.1016\/j.lfs.2012.02.012_bb0130","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S0092-8674(03)00556-7","article-title":"Regulation of vertebrate cellular Mg2+ homeostasis by TRPM7","volume":"114","author":"Schmitz","year":"2003","journal-title":"Cell"},{"key":"10.1016\/j.lfs.2012.02.012_bb0135","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.cyto.2008.01.017","article-title":"Suppressive effect of leflunomide on rat hepatic stellate cell proliferation involves on PDGF-BB-elicited activation of three mitogen-activated protein kinases","volume":"42","author":"Si","year":"2008","journal-title":"Cytokine"},{"key":"10.1016\/j.lfs.2012.02.012_bb0140","doi-asserted-by":"crossref","first-page":"11260","DOI":"10.1074\/jbc.M512885200","article-title":"TRPM7 regulates cell adhesion by controlling the calcium-dependent protease calpain","volume":"281","author":"Su","year":"2006","journal-title":"J Biol Chem"},{"key":"10.1016\/j.lfs.2012.02.012_bb0145","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/j.lfs.2009.01.017","article-title":"Accelerative effect of leflunomide on recovery from hepatic fibrosis involves TRAIL-mediated hepatic stellate cell apoptosis","volume":"84","author":"Tang","year":"2009","journal-title":"Life Sci"},{"key":"10.1016\/j.lfs.2012.02.012_bb0150","first-page":"3760","article-title":"Trp-p8, a novel prostate-specific gene, is up-regulated in prostate cancer and other malignancies and shares high homology with transient receptor potential calcium channel proteins","volume":"61","author":"Tsavaler","year":"2001","journal-title":"Cancer Res"},{"key":"10.1016\/j.lfs.2012.02.012_bb0155","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1002\/hep.21846","article-title":"Increased hepatotoxicity of tumor necrosis factor-related apoptosis-inducing ligand in diseased human liver","volume":"46","author":"Volkmann","year":"2007","journal-title":"Hepatology"},{"issue":"4","key":"10.1016\/j.lfs.2012.02.012_bb0160","first-page":"228","article-title":"Liver fibrosis and cirrhosis-selected cytokines, growth factors and proteins","volume":"68","author":"Wirkowska","year":"2011","journal-title":"Przegl Lek"},{"key":"10.1016\/j.lfs.2012.02.012_bb0165","doi-asserted-by":"crossref","first-page":"4045","DOI":"10.4049\/jimmunol.179.6.4045","article-title":"Functional transient receptor potential melastatin 7 channels are critical for human mast cell survival","volume":"179","author":"Wykes","year":"2007","journal-title":"J Immunol"},{"issue":"4","key":"10.1016\/j.lfs.2012.02.012_bb0170","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1002\/micr.20697","article-title":"A critical role of TRAIL expressed on cotransplanted hepatic stellate cells in prevention of islet allograft rejection","volume":"30","author":"Yang","year":"2010","journal-title":"Microsurgery"},{"issue":"2","key":"10.1016\/j.lfs.2012.02.012_bb0175","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1242\/dmm.004564","article-title":"Transient receptor potential ion channel Trpm7 regulates exocrine pancreatic epithelial proliferation by Mg2+-sensitive Socs3a signaling in development and cancer","volume":"4","author":"Yee","year":"2011","journal-title":"Dis Model Mech"}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320512000835?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320512000835?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,5,7]],"date-time":"2020-05-07T02:23:52Z","timestamp":1588818232000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0024320512000835"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4]]},"references-count":35,"journal-issue":{"issue":"15-16","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["S0024320512000835"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2012.02.012","relation":{},"ISSN":["0024-3205"],"issn-type":[{"value":"0024-3205","type":"print"}],"subject":[],"published":{"date-parts":[[2012,4]]}}}