{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T18:52:03Z","timestamp":1791139923852,"version":"4.1.0"},"reference-count":39,"publisher":"Elsevier BV","issue":"23","content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2013,6]]},"DOI":"10.1016\/j.lfs.2013.04.011","type":"journal-article","created":{"date-parts":[[2013,5,2]],"date-time":"2013-05-02T10:55:22Z","timestamp":1367492122000},"page":"1131-1137","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Angiotensin II Type 1 receptor blockade protects endothelium-derived hyperpolarising factor-mediated relaxation in a rat model of monoarthritis"],"prefix":"10.1016","volume":"92","author":[{"given":"Andrew","family":"MacKenzie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynette","family":"Dunning","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William R.","family":"Ferrell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John C.","family":"Lockhart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.lfs.2013.04.011_bb0005","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1111\/j.1472-8206.2008.00610.x","article-title":"Contribution of endothelium-derived hyperpolarizing factors to the regulation of vascular tone in humans","volume":"22","author":"Bellien","year":"2008","journal-title":"Fundam Clin Pharmacol"},{"key":"10.1016\/j.lfs.2013.04.011_bb0010","first-page":"603","article-title":"A clinical and biochemical assessment of a nonthiol ACE inhibitor (pentopril; CGS-13945) in active rheumatoid arthritis","volume":"17","author":"Bird","year":"1990","journal-title":"J Rheumatol"},{"key":"10.1016\/j.lfs.2013.04.011_bb0015","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1124\/jpet.108.145326","article-title":"Angiotensin II-induced hypertension is associated with a selective inhibition of endothelium-derived hyperpolarizing factor-mediated responses in the rat mesenteric artery","volume":"328","author":"Dal-Ros","year":"2009","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.lfs.2013.04.011_bb0020","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1053\/j.gastro.2009.10.040","article-title":"Losartan prevents portal hypertension-induced, redox-mediated endothelial dysfunction in the mesenteric artery in rats","volume":"138","author":"Dal-Ros","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1016\/j.lfs.2013.04.011_bb0025","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1136\/ard.2003.017269","article-title":"Divergent roles of nitrergic and prostanoid pathways in chronic joint inflammation","volume":"63","author":"Day","year":"2004","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.lfs.2013.04.011_bb0030","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1007\/s00424-010-0830-4","article-title":"Connexins and gap junctions in the EDHF phenomenon and conducted vasomotor responses","volume":"459","author":"de Wit","year":"2010","journal-title":"Pflugers Arch"},{"key":"10.1016\/j.lfs.2013.04.011_bb0035","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/s00210-009-0473-1","article-title":"Improving cardiac gap junction communication as a new antiarrhythmic mechanism: the action of antiarrhythmic peptides","volume":"381","author":"Dhein","year":"2010","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"key":"10.1016\/j.lfs.2013.04.011_bb0040","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1038\/sj.bjp.0703412","article-title":"Potassium does not mimic EDHF in rat mesenteric arteries","volume":"130","author":"Doughty","year":"2000","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.lfs.2013.04.011_bb0045","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1113\/jphysiol.2004.062984","article-title":"Pathophysiology of vascular dysfunction in a rat model of chronic joint inflammation","volume":"557","author":"Egan","year":"2004","journal-title":"J Physiol"},{"key":"10.1016\/j.lfs.2013.04.011_bb0050","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/S0735-1097(02)01689-3","article-title":"Gradual reactivation over time of vascular tissue angiotensin I to angiotensin II conversion during chronic lisinopril therapy in chronic heart failure","volume":"39","author":"Farquharson","year":"2002","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.lfs.2013.04.011_bb0055","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1042\/CS20090096","article-title":"EDHF: an update","volume":"117","author":"Feletou","year":"2009","journal-title":"Clin Sci (Lond)"},{"key":"10.1016\/j.lfs.2013.04.011_bb0060","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1172\/JCI22651","article-title":"The T, cell cometh: interplay between adaptive immunity and cytokine networks in rheumatoid arthritis","volume":"114","author":"Firestein","year":"2004","journal-title":"J Clin Invest"},{"key":"10.1016\/j.lfs.2013.04.011_bb0065","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0014-2999(00)00643-9","article-title":"Role of phospholipase A(2) and myoendothelial gap junctions in melittin-induced arterial relaxation","volume":"406","author":"Hutcheson","year":"2000","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.lfs.2013.04.011_bb0070","doi-asserted-by":"crossref","first-page":"H216","DOI":"10.1152\/ajpheart.00915.2003","article-title":"Angiotensin II receptor blockade corrects altered expression of gap junctions in vascular endothelial cells from hypertensive rats","volume":"287","author":"Kansui","year":"2004","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.lfs.2013.04.011_bb0075","doi-asserted-by":"crossref","first-page":"1878","DOI":"10.1161\/01.CIR.99.14.1878","article-title":"Proinflammatory mediators chronically downregulate the formation of the endothelium-derived hyperpolarizing factor in arteries via a nitric oxide\/cyclic GMP-dependent mechanism","volume":"99","author":"Kessler","year":"1999","journal-title":"Circulation"},{"key":"10.1016\/j.lfs.2013.04.011_bb0080","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1038\/sj.bjp.0706194","article-title":"Two distinct pathways account for EDHF-dependent dilatation in the gracilis artery of dyslipidaemic hApoB+\/+ mice","volume":"145","author":"Krummen","year":"2005","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.lfs.2013.04.011_bb0085","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1253\/circj.CJ-09-0274","article-title":"Rheumatoid arthritis: model of systemic inflammation driving atherosclerosis","volume":"73","author":"Ku","year":"2009","journal-title":"Circ J"},{"key":"10.1016\/j.lfs.2013.04.011_bb0090","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.atherosclerosis.2008.06.008","article-title":"Endothelium-derived hyperpolarizing factor in vascular physiology and cardiovascular disease","volume":"202","author":"Luksha","year":"2009","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.lfs.2013.04.011_bb0095","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.pharmthera.2010.11.001","article-title":"Endothelium-derived vasoactive agents, AT1 receptors and inflammation","volume":"131","author":"MacKenzie","year":"2011","journal-title":"Pharmacol Ther"},{"key":"10.1016\/j.lfs.2013.04.011_bb0100","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1002\/art.20878","article-title":"Cardiovascular death in rheumatoid arthritis: a population-based study","volume":"52","author":"Maradit-Kremers","year":"2005","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.lfs.2013.04.011_bb0105","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1161\/01.STR.0000169929.66497.73","article-title":"Possible role for K+in endothelium-derived hyperpolarizing factor-linked dilatation in rat middle cerebral artery","volume":"36","author":"McNeish","year":"2005","journal-title":"Stroke"},{"key":"10.1016\/j.lfs.2013.04.011_bb0110","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.ejphar.2008.10.032","article-title":"Des-acyl ghrelin fragments evoke endothelium-dependent vasodilatation of rat mesenteric vascular bed via activation of potassium channels","volume":"604","author":"Moazed","year":"2009","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.lfs.2013.04.011_bb0115","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1161\/01.RES.41.1.19","article-title":"Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats","volume":"41","author":"Mulvany","year":"1977","journal-title":"Circ Res"},{"key":"10.1016\/j.lfs.2013.04.011_bb0120","doi-asserted-by":"crossref","first-page":"1646","DOI":"10.1136\/ard.2007.082917","article-title":"Angiotensin receptor blockers reduce erythrocyte sedimentation rate levels in patients with rheumatoid arthritis","volume":"67","author":"Perry","year":"2008","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.lfs.2013.04.011_bb0125","doi-asserted-by":"crossref","first-page":"R130","DOI":"10.1186\/ar3860","article-title":"Treatment with the arginase inhibitor Nw-hydroxy-nor-l-arginine restores endothelial function in rat adjuvant-induced arthritis","volume":"14","author":"Prati","year":"2012","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.lfs.2013.04.011_bb0130","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1002\/art.22335","article-title":"Angiotensin II type 1 receptor as a novel therapeutic target in rheumatoid arthritis: in vivo analyses in rodent models of arthritis and ex vivo analyses in human inflammatory synovitis","volume":"56","author":"Price","year":"2007","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.lfs.2013.04.011_bb0135","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1161\/hc3201.094971","article-title":"Functional evidence for a role of vascular chymase in the production of angiotensin II in isolated human arteries","volume":"104","author":"Richard","year":"2001","journal-title":"Circulation"},{"key":"10.1016\/j.lfs.2013.04.011_bb0140","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1097\/00041552-200105000-00005","article-title":"Proinflammatory actions of angiotensins","volume":"10","author":"Ruiz-Ortega","year":"2001","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"10.1016\/j.lfs.2013.04.011_bb0150","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1161\/01.RES.0000019756.88731.83","article-title":"Involvement of myoendothelial gap junctions in the actions of endothelium-derived hyperpolarizing factor","volume":"90","author":"Sandow","year":"2002","journal-title":"Circ Res"},{"key":"10.1016\/j.lfs.2013.04.011_bb0145","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1113\/jphysiol.2003.058669","article-title":"Developmental changes in myoendothelial gap junction mediated vasodilator activity in the rat saphenous artery","volume":"556","author":"Sandow","year":"2004","journal-title":"J Physiol"},{"key":"10.1016\/j.lfs.2013.04.011_bb0155","doi-asserted-by":"crossref","first-page":"2957","DOI":"10.1161\/01.CIR.0000099844.31524.05","article-title":"Explaining how \u201chigh-grade\u201d systemic inflammation accelerates vascular risk in rheumatoid arthritis","volume":"108","author":"Sattar","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.lfs.2013.04.011_bb0160","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/s003950050156","article-title":"Endothelial cell functions. Relationship to atherogenesis","volume":"94","author":"Toborek","year":"1999","journal-title":"Basic Res Cardiol"},{"key":"10.1016\/j.lfs.2013.04.011_bb0165","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/j.1748-1716.2009.01964.x","article-title":"Endothelial dysfunction and vascular disease","volume":"196","author":"Vanhoutte","year":"2009","journal-title":"Acta Physiol (Oxf)"},{"key":"10.1016\/j.lfs.2013.04.011_bb0170","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1136\/ard.2003.007740","article-title":"Endothelial dysfunction in young patients with rheumatoid arthritis and low disease activity","volume":"63","author":"Vaudo","year":"2004","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.lfs.2013.04.011_bb0175","first-page":"445","article-title":"Cardiovascular morbidity and mortality in patients with seropositive rheumatoid arthritis in Northern Sweden","volume":"24","author":"Wallberg-Jonsson","year":"1997","journal-title":"J Rheumatol"},{"key":"10.1016\/j.lfs.2013.04.011_bb0180","first-page":"1610","article-title":"Neuropeptide degrading enzymes in normal and inflamed human synovium","volume":"142","author":"Walsh","year":"1993","journal-title":"Am J Pathol"},{"key":"10.1016\/j.lfs.2013.04.011_bb0185","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1111\/j.1476-5381.1994.tb13091.x","article-title":"AT1 receptor characteristics of angiotensin analogue binding in human synovium","volume":"112","author":"Walsh","year":"1994","journal-title":"Br J Pharmacol"},{"key":"10.1016\/j.lfs.2013.04.011_bb0190","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1002\/art.1780370408","article-title":"The mortality of rheumatoid arthritis","volume":"37","author":"Wolfe","year":"1994","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.lfs.2013.04.011_bb0195","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1161\/01.RES.73.1.205","article-title":"Tumor necrosis factor downregulates an endothelial nitric oxide synthase mRNA by shortening its half-life","volume":"73","author":"Yoshizumi","year":"1993","journal-title":"Circ Res"}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320513002361?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320513002361?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,7,26]],"date-time":"2020-07-26T05:28:56Z","timestamp":1595741336000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0024320513002361"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6]]},"references-count":39,"journal-issue":{"issue":"23","published-print":{"date-parts":[[2013,6]]}},"alternative-id":["S0024320513002361"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2013.04.011","relation":{},"ISSN":["0024-3205"],"issn-type":[{"value":"0024-3205","type":"print"}],"subject":[],"published":{"date-parts":[[2013,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Angiotensin II Type 1 receptor blockade protects endothelium-derived hyperpolarising factor-mediated relaxation in a rat model of monoarthritis","name":"articletitle","label":"Article Title"},{"value":"Life Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lfs.2013.04.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}