{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T17:43:33Z","timestamp":1790358213014,"version":"4.1.0"},"reference-count":19,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T00:00:00Z","timestamp":1414800000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,2,11]],"date-time":"2014-02-11T00:00:00Z","timestamp":1392076800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2014,11]]},"DOI":"10.1016\/j.lfs.2014.01.077","type":"journal-article","created":{"date-parts":[[2014,2,11]],"date-time":"2014-02-11T08:01:23Z","timestamp":1392105683000},"page":"414-419","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":69,"title":["Long-term patient survival with idiopathic\/heritable pulmonary arterial hypertension treated at a single center in Japan"],"prefix":"10.1016","volume":"118","author":[{"given":"Aiko","family":"Ogawa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kentaro","family":"Ejiri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiromi","family":"Matsubara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.lfs.2014.01.077_bb0005","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1016\/S0735-1097(02)02012-0","article-title":"Long-term intravenous epoprostenol infusion in primary pulmonary hypertension: prognostic factors and survival","volume":"40","author":"Sitbon","year":"2002","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.lfs.2014.01.077_bb0010","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1183\/09031936.05.00054804","article-title":"Survival with first-line bosentan in patients with primary pulmonary hypertension","volume":"25","author":"McLaughlin","year":"2005","journal-title":"Eur Respir J"},{"key":"10.1016\/j.lfs.2014.01.077_bb0015","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1378\/chest.10-0969","article-title":"Long-term treatment with sildenafil citrate in pulmonary arterial hypertension: the SUPER-2 Study","volume":"140","author":"Rubin","year":"2011","journal-title":"Chest"},{"key":"10.1016\/j.lfs.2014.01.077_bb0020","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1183\/09031936.00139009","article-title":"Guidelines for the diagnosis and treatment of pulmonary hypertension","volume":"34","author":"Galie","year":"2009","journal-title":"Eur Respir J"},{"key":"10.1016\/j.lfs.2014.01.077_bb0025","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1161\/CIRCULATIONAHA.109.911818","article-title":"Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era","volume":"122","author":"Humbert","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.lfs.2014.01.077_bb0030","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1183\/09031936.00196611","article-title":"Predicting survival in pulmonary arterial hypertension in the UK","volume":"40","author":"Lee","year":"2012","journal-title":"Eur Respir J"},{"key":"10.1016\/j.lfs.2014.01.077_bb0035","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1378\/chest.11-1460","article-title":"An evaluation of long-term survival from time of diagnosis in pulmonary arterial hypertension from the REVEAL Registry","volume":"142","author":"Benza","year":"2012","journal-title":"Chest"},{"key":"10.1016\/j.lfs.2014.01.077_bb0040","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1378\/chest.10-2327","article-title":"Survival of Chinese patients with pulmonary arterial hypertension in the modern treatment era","volume":"140","author":"Zhang","year":"2011","journal-title":"Chest"},{"key":"10.1016\/j.lfs.2014.01.077_bb0045","doi-asserted-by":"crossref","first-page":"343","DOI":"10.7326\/0003-4819-115-5-343","article-title":"Survival in patients with primary pulmonary hypertension. Results from a national prospective registry","volume":"115","author":"D'Alonzo","year":"1991","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.lfs.2014.01.077_bb0050","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1253\/circj.72.1142","article-title":"Additional effects of bosentan in patients with idiopathic pulmonary arterial hypertension already treated with high-dose epoprostenol","volume":"72","author":"Akagi","year":"2008","journal-title":"Circ J"},{"key":"10.1016\/j.lfs.2014.01.077_bb0055","doi-asserted-by":"crossref","first-page":"2200","DOI":"10.1253\/circj.CJ-10-0190","article-title":"Marked hemodynamic improvements by high-dose epoprostenol therapy in patients with idiopathic pulmonary arterial hypertension","volume":"74","author":"Akagi","year":"2010","journal-title":"Circ J"},{"key":"10.1016\/j.lfs.2014.01.077_bb0060","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1378\/chest.09-1140","article-title":"Pulmonary arterial hypertension: baseline characteristics from the REVEAL Registry","volume":"137","author":"Badesch","year":"2010","journal-title":"Chest"},{"key":"10.1016\/j.lfs.2014.01.077_bb0065","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1183\/09031936.00092311","article-title":"The prognostic impact of follow-up assessments in patients with idiopathic pulmonary arterial hypertension","volume":"39","author":"Nickel","year":"2012","journal-title":"Eur Respir J"},{"key":"10.1016\/j.lfs.2014.01.077_bb0070","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1378\/chest.81.2.151","article-title":"Longterm follow-up of patients with pulmonary thromboembolism. Late prognosis and evolution of hemodynamic and respiratory data","volume":"81","author":"Riedel","year":"1982","journal-title":"Chest"},{"key":"10.1016\/j.lfs.2014.01.077_bb0075","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1378\/chest.119.3.818","article-title":"Prognostic factors in medically treated patients with chronic pulmonary embolism","volume":"119","author":"Lewczuk","year":"2001","journal-title":"Chest"},{"key":"10.1016\/j.lfs.2014.01.077_bb0080","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1183\/09059180.00005412","article-title":"Challenges in the diagnosis and treatment of pulmonary arterial hypertension","volume":"21","author":"Vachiery","year":"2012","journal-title":"Eur Respir Rev"},{"key":"10.1016\/j.lfs.2014.01.077_bb0085","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/j.healun.2011.12.011","article-title":"Prognostic factors in severe pulmonary hypertension patients who need parenteral prostanoid therapy: the impact of late referral","volume":"31","author":"Badagliacca","year":"2012","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.lfs.2014.01.077_bb0090","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1016\/j.jacc.2012.01.083","article-title":"Do changes of 6-minute walk distance predict clinical events in patients with pulmonary arterial hypertension? A meta-analysis of 22 randomized trials","volume":"60","author":"Savarese","year":"2012","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.lfs.2014.01.077_bb0095","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/j.ijcard.2012.10.026","article-title":"Elderly patients diagnosed with idiopathic pulmonary arterial hypertension: results from the COMPERA Registry","volume":"168","author":"Hoeper","year":"2013","journal-title":"Int J Cardiol"}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002432051400215X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002432051400215X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,6]],"date-time":"2018-10-06T14:58:09Z","timestamp":1538837889000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002432051400215X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,11]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["S002432051400215X"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2014.01.077","relation":{},"ISSN":["0024-3205"],"issn-type":[{"value":"0024-3205","type":"print"}],"subject":[],"published":{"date-parts":[[2014,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Long-term patient survival with idiopathic\/heritable pulmonary arterial hypertension treated at a single center in Japan","name":"articletitle","label":"Article Title"},{"value":"Life Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lfs.2014.01.077","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 The Authors. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}