{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T22:39:57Z","timestamp":1783463997441,"version":"3.55.0"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,4,1]],"date-time":"2016-04-01T00:00:00Z","timestamp":1459468800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81273835"],"award-info":[{"award-number":["81273835"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81373778"],"award-info":[{"award-number":["81373778"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81403450"],"award-info":[{"award-number":["81403450"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Youth Scientific Project of the Fujian Province Health and Family Planning Commission","award":["2014-1-70"],"award-info":[{"award-number":["2014-1-70"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2016,4]]},"DOI":"10.1016\/j.lfs.2016.01.045","type":"journal-article","created":{"date-parts":[[2016,3,14]],"date-time":"2016-03-14T14:36:33Z","timestamp":1457966193000},"page":"313-322","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":73,"special_numbering":"C","title":["Electroacupunctre improves motor impairment via inhibition of microglia-mediated neuroinflammation in the sensorimotor cortex after ischemic stroke"],"prefix":"10.1016","volume":"151","author":[{"given":"Weilin","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xian","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanli","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiehua","family":"Xue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guanhao","family":"Shang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Tao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8699-0839","authenticated-orcid":false,"given":"Lidian","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.lfs.2016.01.045_bb0005","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1016\/S0140-6736(08)60694-7","volume":"371","author":"Donnan","year":"2008","journal-title":"Stroke Lancet"},{"key":"10.1016\/j.lfs.2016.01.045_bb0010","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.3109\/09638288.2014.963706","article-title":"A systematic review of studies reporting multivariable models to predict functional outcomes after post-stroke inpatient rehabilitation","volume":"37","author":"Meyer","year":"2014","journal-title":"Disabil. Rehabil."},{"key":"10.1016\/j.lfs.2016.01.045_bb0015","first-page":"737","article-title":"Efficacy observation of dysphagia after acute stroke treated with acupuncture and functional electric stimulation","volume":"34","author":"Chang","year":"2014","journal-title":"Zhongguo Zhen Jiu"},{"key":"10.1016\/j.lfs.2016.01.045_bb0020","doi-asserted-by":"crossref","first-page":"2604","DOI":"10.1161\/01.STR.0000035908.74261.C9","article-title":"Does acupuncture improve motor recovery after stroke? A meta-analysis of randomized controlled trials","volume":"33","author":"Sze","year":"2002","journal-title":"Stroke"},{"key":"10.1016\/j.lfs.2016.01.045_bb0025","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1142\/S0192415X12500516","article-title":"Acupuncture intervention in ischemic stroke: a randomized controlled prospective study","volume":"40","author":"Shen","year":"2012","journal-title":"Am. J. Chin. Med."},{"key":"10.1016\/j.lfs.2016.01.045_bb0030","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1002\/jnr.20562","article-title":"Microglia in health and disease","volume":"81","author":"Kim","year":"2005","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.lfs.2016.01.045_bb0035","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1016\/j.neuroscience.2008.11.043","article-title":"Kv1.1 expression in microglia regulates production and release of proinflammatory cytokines, endothelins and nitric oxide","volume":"158","author":"Wu","year":"2009","journal-title":"Neuroscience"},{"key":"10.1016\/j.lfs.2016.01.045_bb0040","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1038\/sj.bjp.0706400","article-title":"The role of inflammation in CNS injury and disease","volume":"147","author":"Lucas","year":"2006","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.lfs.2016.01.045_bb0045","first-page":"842","article-title":"Nanog inhibits lipopolysaccharide-induced expression of pro-inflammatory cytokines by blocking NF-kappaB transcriptional activity in rat primary microglial cells","volume":"5","author":"Zhou","year":"2012","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.lfs.2016.01.045_bb0050","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1016\/j.neuroscience.2008.07.031","article-title":"Systemic infection and inflammation in acute CNS injury and chronic neurodegeneration: underlying mechanisms","volume":"158","author":"Teeling","year":"2009","journal-title":"Neuroscience"},{"key":"10.1016\/j.lfs.2016.01.045_bb0055","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1159\/000096017","article-title":"Pathophysiology of acute ischaemic stroke: an analysis of common signalling mechanisms and identification of new molecular targets","volume":"73","author":"Mitsios","year":"2006","journal-title":"Pathobiology"},{"key":"10.1016\/j.lfs.2016.01.045_bb0060","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2014.586","article-title":"Inhibition of immunoproteasome reduces infarction volume and attenuates inflammatory reaction in a rat model of ischemic stroke","volume":"6","author":"Chen","year":"2015","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.lfs.2016.01.045_bb0065","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1007\/s12035-013-8460-4","article-title":"Reciprocal modulation between microglia and astrocyte in reactive gliosis following the CNS injury","volume":"48","author":"Gao","year":"2013","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.lfs.2016.01.045_bb0070","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.toxlet.2015.09.015","article-title":"Lead exposure induced microgliosis and astrogliosis in hippocampus of young mice potentially by triggering TLR4-MyD88-NF\u03baB signaling cascades","volume":"239","author":"Liu","year":"2015","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.lfs.2016.01.045_bb0075","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.brainres.2014.01.013","article-title":"Involvement of p38 MAPK in reactive astrogliosis induced by ischemic stroke","volume":"1551","author":"Roy Choudhury","year":"2014","journal-title":"Brain Res."},{"key":"10.1016\/j.lfs.2016.01.045_bb0080","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/S0300-483X(03)00152-5","article-title":"Antioxidant nutrients and hypoxia\/ischemia brain injury in rodents","volume":"189","author":"Ikeda","year":"2003","journal-title":"Toxicology"},{"key":"10.1016\/j.lfs.2016.01.045_bb0085","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1161\/STROKEAHA.114.007581","article-title":"Cortical selective neuronal loss, impaired behavior, and normal magnetic resonance imaging in a new rat model of true transient ischemic attacks","volume":"46","author":"Ejaz","year":"2015","journal-title":"Stroke"},{"key":"10.1016\/j.lfs.2016.01.045_bb0090","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1093\/brain\/awv079","article-title":"Multiple therapeutic effects of progranulin on experimental acute ischaemic stroke","volume":"138","author":"Kanazawa","year":"2015","journal-title":"Brain"},{"key":"10.1016\/j.lfs.2016.01.045_bb0095","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0120203","article-title":"Neuroprotective effect of 6-paradol in focal cerebral ischemia involves the attenuation of neuroinflammatory responses in activated microglia","volume":"10","author":"Gaire","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.lfs.2016.01.045_bb0100","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.neuroscience.2015.02.002","article-title":"HAMI 3379, a CysLT2R antagonist, dose-and time-dependently attenuates brain injury and inhibits microglial inflammation after focal cerebral ischemia in rats","volume":"291","author":"Shi","year":"2015","journal-title":"Neuroscience"},{"key":"10.1016\/j.lfs.2016.01.045_bb0105","first-page":"625","article-title":"Effect of electroacupuncture on inflammatory injury induced by intestinal ischemia\/reperfusion in rats","volume":"32","author":"Yao","year":"2012","journal-title":"Zhongguo Zhen Jiu"},{"key":"10.1016\/j.lfs.2016.01.045_bb0110","article-title":"Effects of acupuncture at GV20 and ST36 on the expression of matrix metalloproteinase 2, aquaporin 4, and aquaporin 9 in rats subjected to cerebral ischemia\/reperfusion injury","volume":"9","author":"Xu","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.lfs.2016.01.045_bb0115","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1186\/1472-6882-14-127","article-title":"Electroacupuncture improves recovery after hemorrhagic brain injury by inducing the expression of angiopoietin-1 and -2 in rats","volume":"14","author":"Zhou","year":"2014","journal-title":"BMC Complement Altern. Med."},{"key":"10.1016\/j.lfs.2016.01.045_bb0120","doi-asserted-by":"crossref","first-page":"75","DOI":"10.3892\/ijmm.2012.1184","article-title":"Electroacupuncture exerts anti-inflammatory effects in cerebral ischemia-reperfusion injured rats via suppression of the TLR4\/NF-kappaB pathway","volume":"31","author":"Lan","year":"2013","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.lfs.2016.01.045_bb0125","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1161\/01.STR.20.1.84","article-title":"Reversible middle cerebral artery occlusion without craniectomy in rats","volume":"20","author":"Longa","year":"1989","journal-title":"Stroke"},{"key":"10.1016\/j.lfs.2016.01.045_bb0130","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1179\/174313209X414506","article-title":"Electroacupuncture improves neurological deficits and enhances proliferation and differentiation of endogenous nerve stem cells in rats with focal cerebral ischemia","volume":"32","author":"Tao","year":"2010","journal-title":"Neurol. Res."},{"key":"10.1016\/j.lfs.2016.01.045_bb0135","doi-asserted-by":"crossref","first-page":"2682","DOI":"10.1161\/hs1101.098367","article-title":"Intravenous administration of human umbilical cord blood reduces behavioral deficits after stroke in rats","volume":"32","author":"Chen","year":"2001","journal-title":"Stroke"},{"key":"10.1016\/j.lfs.2016.01.045_bb0140","first-page":"410972","article-title":"Gait impairment in a rat model of focal cerebral ischemia","volume":"2013","author":"Parkkinen","year":"2013","journal-title":"Stroke Res. Treat."},{"key":"10.1016\/j.lfs.2016.01.045_bb0145","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.jneumeth.2011.01.010","article-title":"Long-term behavioral assessment of function in an experimental model for ischemic stroke","volume":"196","author":"Encarnacion","year":"2011","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.lfs.2016.01.045_bb0150","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.jneumeth.2012.12.021","article-title":"Characterization of long-term functional outcome in a murine model of mild brain ischemia","volume":"213","author":"Balkaya","year":"2013","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.lfs.2016.01.045_bb0155","doi-asserted-by":"crossref","first-page":"2932","DOI":"10.1161\/STROKEAHA.110.612788","article-title":"Mesenchymal stem cells primed with valproate and lithium robustly migrate to infarcted regions and facilitate recovery in a stroke model","volume":"42","author":"Tsai","year":"2011","journal-title":"Stroke"},{"key":"10.1016\/j.lfs.2016.01.045_bb0160","doi-asserted-by":"crossref","first-page":"204","DOI":"10.3109\/00207454.2013.840781","article-title":"Electroacupuncture enhances hippocampal NSCs proliferation in cerebral ischemia-reperfusion injured rats via activation of notch signaling pathway","volume":"124","author":"Tao","year":"2014","journal-title":"Int. J. Neurosci."},{"key":"10.1016\/j.lfs.2016.01.045_bb0165","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.brainres.2009.04.002","article-title":"Adiponectin protects against cerebral ischemia-reperfusion injury through anti-inflammatory action","volume":"1273","author":"Chen","year":"2009","journal-title":"Brain Res."},{"key":"10.1016\/j.lfs.2016.01.045_bb0170","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1161\/STROKEAHA.107.494542","article-title":"Inflammatory and injury responses to ischemic stroke in obese mice","volume":"39","author":"Terao","year":"2008","journal-title":"Stroke"},{"key":"10.1016\/j.lfs.2016.01.045_bb0175","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1189\/jlb.1109766","article-title":"Inflammatory mechanisms in ischemic stroke: role of inflammatory cells","volume":"87","author":"Jin","year":"2010","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.lfs.2016.01.045_bb0180","first-page":"190","article-title":"Clinical experience in acupuncture treatment of apoplexy","volume":"25","author":"Liu","year":"2005","journal-title":"J. Tradit. Chin. Med."},{"key":"10.1016\/j.lfs.2016.01.045_bb0185","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1186\/1742-2094-10-63","article-title":"Delayed brain ischemia tolerance induced by electroacupuncture pretreatment is mediated via MCP-induced protein 1","volume":"10","author":"Jin","year":"2013","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.lfs.2016.01.045_bb0190","doi-asserted-by":"crossref","first-page":"9490","DOI":"10.1038\/srep09490","article-title":"Involvement of GluR2 up-regulation in neuroprotection by electroacupuncture pretreatment via cannabinoid CB1 receptor in mice","volume":"5","author":"Liu","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.lfs.2016.01.045_bb0195","doi-asserted-by":"crossref","first-page":"773","DOI":"10.3109\/02699051003610482","article-title":"A study of astrocyte activation in the periinfarct region after cerebral ischemia with electroacupuncture","volume":"24","author":"Han","year":"2010","journal-title":"Brain Inj."},{"key":"10.1016\/j.lfs.2016.01.045_bb0200","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1142\/S0192415X09006990","article-title":"Acupuncture stimulation improves balance function in stroke patients: a single-blinded controlled, randomized study","volume":"37","author":"Liu","year":"2009","journal-title":"Am. J. Chin. Med."},{"key":"10.1016\/j.lfs.2016.01.045_bb0205","first-page":"635","article-title":"Acupoint electrogymnastics therapy for treatment of apoplectic hemiplegia: a multicenter randomized control study","volume":"28","author":"Yang","year":"2008","journal-title":"Zhongguo Zhen Jiu."},{"key":"10.1016\/j.lfs.2016.01.045_bb0210","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.brainres.2005.09.060","article-title":"Electroacupuncture regulates NMDA receptor NR1 subunit expression via PI3-K pathway in a rat model of cerebral ischemia-reperfusion","volume":"1064","author":"Sun","year":"2005","journal-title":"Brain Res."},{"key":"10.1016\/j.lfs.2016.01.045_bb0215","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.neuropharm.2008.01.005","article-title":"Mechanisms of ischemic brain damage","volume":"55","author":"Doyle","year":"2008","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.lfs.2016.01.045_bb0220","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1186\/1479-5876-7-97","article-title":"Inflammatory mechanisms in ischemic stroke: therapeutic approaches","volume":"7","author":"Lakhan","year":"2009","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.lfs.2016.01.045_bb0225","doi-asserted-by":"crossref","first-page":"953162","DOI":"10.1155\/2013\/953162","article-title":"Effects of pretreatment with a combination of melatonin and electroacupuncture in a rat model of transient focal cerebral ischemia","volume":"2013","author":"Liu","year":"2013","journal-title":"Evid. Based Complement. Alternat. Med."},{"key":"10.1016\/j.lfs.2016.01.045_bb0230","doi-asserted-by":"crossref","first-page":"989340","DOI":"10.1155\/2014\/989340","article-title":"Electroacupuncture treatment improves neurological function associated with regulation of tight junction proteins in rats with cerebral ischemia reperfusion injury","volume":"2014","author":"Zhang","year":"2014","journal-title":"Evid. Based Complement. Alternat. Med."},{"key":"10.1016\/j.lfs.2016.01.045_bb0235","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1097\/WCO.0b013e32813ba151","article-title":"Inflammation and ischemic stroke","volume":"20","author":"Muir","year":"2007","journal-title":"Curr. Opin. Neurol."},{"key":"10.1016\/j.lfs.2016.01.045_bb0240","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1161\/STROKEAHA.108.534503","article-title":"Temporal and spatial dynamics of cerebral immune cell accumulation in stroke","volume":"40","author":"Gelderblom","year":"2009","journal-title":"Stroke"},{"key":"10.1016\/j.lfs.2016.01.045_bb0245","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0022-510X(93)90285-7","article-title":"The possible contribution of microglia and macrophages to delayed neuronal death after ischemia","volume":"114","author":"Lees","year":"1993","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.lfs.2016.01.045_bb0250","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.jneuroim.2006.11.014","article-title":"The inflammatory response in stroke","volume":"184","author":"Wang","year":"2007","journal-title":"J. Neuroimmunol."},{"key":"10.1016\/j.lfs.2016.01.045_bb0255","first-page":"73","article-title":"Microglia and ischemic stroke: a double-edged sword","volume":"5","author":"Patel","year":"2013","journal-title":"Int. J. Physiol. Pathophysiol. Pharmacol."},{"key":"10.1016\/j.lfs.2016.01.045_bb0260","doi-asserted-by":"crossref","first-page":"15769","DOI":"10.1073\/pnas.95.26.15769","article-title":"Tetracyclines inhibit microglial activation and are neuroprotective in global brain ischemia","volume":"95","author":"Yrj\u00e4nheikki","year":"1998","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.lfs.2016.01.045_bb0265","doi-asserted-by":"crossref","first-page":"2146","DOI":"10.2174\/0929867321666131228203906","article-title":"Targeting microglial activation in stroke therapy: pharmacological tools and gender effects","volume":"21","author":"Chen","year":"2014","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.lfs.2016.01.045_bb0270","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1002\/glia.21058","article-title":"Glucosamine exerts a neuroprotective effect via suppression of inflammation in rat brain ischemia\/reperfusion injury","volume":"58","author":"Hwang","year":"2010","journal-title":"Glia"},{"key":"10.1016\/j.lfs.2016.01.045_bb0275","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.pneurobio.2009.01.003","article-title":"Periventricular white matter damage in the hypoxic neonatal brain: role of microglial cells","volume":"87","author":"Kaur","year":"2009","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.lfs.2016.01.045_bb0280","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1038\/jcbfm.2014.107","article-title":"Mouse intracerebral hemorrhage models produce different degrees of initial and delayed damage, axonal sprouting, and recovery","volume":"34","author":"Barratt","year":"2014","journal-title":"J. Cereb. Blood Flow Metab."},{"key":"10.1016\/j.lfs.2016.01.045_bb0285","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0090584","article-title":"Long-term functional consequences and ongoing cerebral inflammation after subarachnoid hemorrhage in the rat","volume":"9","author":"Kooijman","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.lfs.2016.01.045_bb0290","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.expneurol.2013.11.019","article-title":"Plasticity beyond peri-infarct cortex: spinal up regulation of structural plasticity, neurotrophins, and inflammatory cytokines during recovery from cortical stroke","volume":"252","author":"Sist","year":"2014","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.lfs.2016.01.045_bb0295","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.brainres.2013.02.010","article-title":"Microglial CD14 activated by iNOS contributes to neuroinflammation in cerebral ischemia","volume":"1506","author":"Zhou","year":"2013","journal-title":"Brain Res."},{"key":"10.1016\/j.lfs.2016.01.045_bb0300","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1111\/j.1749-6632.2010.05735.x","article-title":"NF-kappaB and innate immunity in ischemic stroke","volume":"1207","author":"Harari","year":"2010","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.lfs.2016.01.045_bb0305","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1002\/jnr.23267","article-title":"Human mesenchymal stem cell transplantation changes proinflammatory gene expression through a nuclear factor-kappaB-dependent pathway in a rat focal cerebral ischemic model","volume":"91","author":"Wang","year":"2013","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.lfs.2016.01.045_bb0310","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/j.expneurol.2014.05.009","article-title":"Inhibition of mitogen-activated protein kinase phosphatase-1 (MKP-1) increases experimental stroke injury","volume":"261","author":"Liu","year":"2014","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.lfs.2016.01.045_bb0315","doi-asserted-by":"crossref","first-page":"3718","DOI":"10.3390\/ijms14023718","article-title":"Exercise therapy downregulates the overexpression of TLR4, TLR2, MyD88 and NF-\u03baB after cerebral ischemia in rats","volume":"14","author":"Ma","year":"2013","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.lfs.2016.01.045_bb0320","doi-asserted-by":"crossref","first-page":"2221","DOI":"10.1523\/JNEUROSCI.5643-07.2008","article-title":"Mechanisms of microglia-mediated neurotoxicity in a new model of the stroke penumbra","volume":"28","author":"Kaushal","year":"2008","journal-title":"J. Neurosci."},{"key":"10.1016\/j.lfs.2016.01.045_bb0325","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0049701","article-title":"Paeoniflorin protects against ischemia-induced brain damages in rats via inhibiting MAPKs\/NF-\u03baB-mediated inflammatory responses","volume":"7","author":"Guo","year":"2012","journal-title":"PLoS One"}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320516300443?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320516300443?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,14]],"date-time":"2018-09-14T05:56:26Z","timestamp":1536904586000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0024320516300443"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4]]},"references-count":65,"alternative-id":["S0024320516300443"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2016.01.045","relation":{},"ISSN":["0024-3205"],"issn-type":[{"value":"0024-3205","type":"print"}],"subject":[],"published":{"date-parts":[[2016,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Electroacupunctre improves motor impairment via inhibition of microglia-mediated neuroinflammation in the sensorimotor cortex after ischemic stroke","name":"articletitle","label":"Article Title"},{"value":"Life Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lfs.2016.01.045","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}