{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T01:32:00Z","timestamp":1790040720542,"version":"4.0.1"},"reference-count":185,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T00:00:00Z","timestamp":1470009600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"crossref","award":["15POST25090329"],"award-info":[{"award-number":["15POST25090329"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"crossref","award":["FAPESP 2004\/13796-9"],"award-info":[{"award-number":["FAPESP 2004\/13796-9"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"crossref","award":["2013\/08216-2"],"award-info":[{"award-number":["2013\/08216-2"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"crossref"}]},{"name":"L'\u00d3REAL - For Women in Sciences"},{"name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Mato Grosso","award":["FAPEMAT 151371\/2014"],"award-info":[{"award-number":["FAPEMAT 151371\/2014"]}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"crossref","award":["CNPq 471675\/2013-0"],"award-info":[{"award-number":["CNPq 471675\/2013-0"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000050","name":"National Heart Lung and Blood Institute","doi-asserted-by":"crossref","award":["HL69999"],"award-info":[{"award-number":["HL69999"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000050","name":"National Heart Lung and Blood Institute","doi-asserted-by":"crossref","award":["HL95499"],"award-info":[{"award-number":["HL95499"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Life Sciences"],"published-print":{"date-parts":[[2016,8]]},"DOI":"10.1016\/j.lfs.2016.02.093","type":"journal-article","created":{"date-parts":[[2016,3,3]],"date-time":"2016-03-03T11:06:02Z","timestamp":1457003162000},"page":"20-29","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":45,"special_numbering":"C","title":["Role of the endothelin system in sexual dimorphism in cardiovascular and renal diseases"],"prefix":"10.1016","volume":"159","author":[{"given":"Eman Y.","family":"Gohar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda R.","family":"Giachini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David M.","family":"Pollock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita C.","family":"Tostes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0005","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1097\/00004872-200401000-00003","article-title":"Worldwide prevalence of hypertension: a systematic review","volume":"22","author":"Kearney","year":"2004","journal-title":"J. Hypertens."},{"issue":"20","key":"10.1016\/j.lfs.2016.02.093_bb0010","doi-asserted-by":"crossref","first-page":"2043","DOI":"10.1001\/jama.2010.650","article-title":"US trends in prevalence, awareness, treatment, and control of hypertension, 1988-2008","volume":"303","author":"Egan","year":"2010","journal-title":"JAMA"},{"issue":"5","key":"10.1016\/j.lfs.2016.02.093_bb0015","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1161\/HYPERTENSIONAHA.108.113357","article-title":"Trends in hypertension prevalence, awareness, treatment, and control rates in United States adults between 1988-1994 and 1999-2004","volume":"52","author":"Cutler","year":"2008","journal-title":"Hypertension"},{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0020","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/2042-6410-3-7","article-title":"Sex differences in primary hypertension","volume":"3","author":"Sandberg","year":"2012","journal-title":"Biol. Sex Differ."},{"issue":"9147","key":"10.1016\/j.lfs.2016.02.093_bb0025","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0140-6736(98)10279-9","article-title":"Lifetime risk of developing coronary heart disease","volume":"353","author":"Lloyd-Jones","year":"1999","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.lfs.2016.02.093_bb0030","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1161\/STROKEAHA.108.542894","article-title":"Gender differences in stroke incidence and poststroke disability in the Framingham heart study","volume":"40","author":"Petrea","year":"2009","journal-title":"Stroke"},{"issue":"24","key":"10.1016\/j.lfs.2016.02.093_bb0035","doi-asserted-by":"crossref","first-page":"3068","DOI":"10.1161\/01.CIR.0000039105.49749.6F","article-title":"Lifetime risk for developing congestive heart failure: the Framingham Heart Study","volume":"106","author":"Lloyd-Jones","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.lfs.2016.02.093_bb0040","doi-asserted-by":"crossref","first-page":"g5992","DOI":"10.1136\/bmj.g5992","article-title":"Sex differences in lifetime risk and first manifestation of cardiovascular disease: prospective population based cohort study","volume":"349","author":"Leening","year":"2014","journal-title":"BMJ"},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0045","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1042\/CS20070169","article-title":"Endothelin, sex and hypertension","volume":"114","author":"Tostes","year":"2008","journal-title":"Clin. Sci. (Lond.)"},{"issue":"4","key":"10.1016\/j.lfs.2016.02.093_bb0050","doi-asserted-by":"crossref","first-page":"S188","DOI":"10.1097\/00004872-198812040-00056","article-title":"A novel peptide vasoconstrictor, endothelin, is produced by vascular endothelium and modulates smooth muscle Ca2+ channels","volume":"6","author":"Yanagisawa","year":"1988","journal-title":"J. Hypertens. Suppl."},{"issue":"8","key":"10.1016\/j.lfs.2016.02.093_bb0055","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1139\/Y08-059","article-title":"Endothelin: 20years from discovery to therapy","volume":"86","author":"Barton","year":"2008","journal-title":"Can. J. Physiol. Pharmacol."},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0060","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1111\/j.1476-5381.2012.02195.x","article-title":"The role of the paracrine\/autocrine mediator endothelin-1 in regulation of cardiac contractility and growth","volume":"168","author":"Drawnel","year":"2013","journal-title":"Br. J. Pharmacol."},{"issue":"4","key":"10.1016\/j.lfs.2016.02.093_bb0065","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1161\/01.RES.72.4.757","article-title":"Characterization of protein kinase C isotype expression in adult rat heart. Protein kinase C-epsilon is a major isotype present, and it is activated by phorbol esters, epinephrine, and endothelin","volume":"72","author":"Bogoyevitch","year":"1993","journal-title":"Circ. Res."},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0070","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1016\/S0021-9258(17)42228-9","article-title":"Endothelin-1 and fibroblast growth factors stimulate the mitogen-activated protein kinase signaling cascade in cardiac myocytes. The potential role of the cascade in the integration of two signaling pathways leading to myocyte hypertrophy","volume":"269","author":"Bogoyevitch","year":"1994","journal-title":"J. Biol. Chem."},{"issue":"4","key":"10.1016\/j.lfs.2016.02.093_bb0075","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1172\/JCI114822","article-title":"Endothelin enhances the contractile responsiveness of adult rat ventricular myocytes to calcium by a pertussis toxin-sensitive pathway","volume":"86","author":"Kelly","year":"1990","journal-title":"J. Clin. Invest."},{"issue":"4","key":"10.1016\/j.lfs.2016.02.093_bb0080","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1016\/j.cardiores.2005.04.020","article-title":"Endothelin receptor \u2013 a blockade decreases ventricular arrhythmias after myocardial infarction in rats","volume":"67","author":"Baltogiannis","year":"2005","journal-title":"Cardiovasc. Res."},{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0085","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.ejheart.2004.08.001","article-title":"Comparison of selective ET(A) and ET(B) receptor antagonists in patients with chronic heart failure","volume":"7","author":"Cowburn","year":"2005","journal-title":"Eur. J. Heart Fail."},{"issue":"Suppl. 3","key":"10.1016\/j.lfs.2016.02.093_bb0090","first-page":"S2","article-title":"Vascular biology of endothelin","volume":"32","author":"Schiffrin","year":"1998","journal-title":"J. Cardiovasc. Pharmacol."},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0095","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1097\/MNH.0b013e32834f0092","article-title":"Endothelin in hypertension: an update","volume":"21","author":"Rautureau","year":"2012","journal-title":"Curr. Opin. Nephrol. Hypertens."},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0100","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1161\/01.HYP.0000153051.56460.6a","article-title":"NADPH oxidase inhibition attenuates oxidative stress but not hypertension produced by chronic ET-1","volume":"45","author":"Elmarakby","year":"2005","journal-title":"Hypertension"},{"issue":"5","key":"10.1016\/j.lfs.2016.02.093_bb0105","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1161\/HYPERTENSIONAHA.111.183368","article-title":"Endothelin 1 activation of endothelin A receptor\/NADPH oxidase pathway and diminished antioxidants critically contribute to endothelial progenitor cell reduction and dysfunction in salt-sensitive hypertension","volume":"59","author":"Chen","year":"2012","journal-title":"Hypertension"},{"issue":"6","key":"10.1016\/j.lfs.2016.02.093_bb0110","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.2353\/ajpath.2006.051331","article-title":"Shigatoxin-induced endothelin-1 expression in cultured podocytes autocrinally mediates actin remodeling","volume":"169","author":"Morigi","year":"2006","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.lfs.2016.02.093_bb0115","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1159\/000328692","article-title":"Endothelin and podocyte injury in chronic kidney disease","volume":"172","author":"Fligny","year":"2011","journal-title":"Contrib. Nephrol."},{"issue":"4","key":"10.1016\/j.lfs.2016.02.093_bb0120","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1007\/s00125-010-2021-4","article-title":"Endothelin receptor A-specific stimulation of glomerular inflammation and injury in a streptozotocin-induced rat model of diabetes","volume":"54","author":"Saleh","year":"2011","journal-title":"Diabetologia"},{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0125","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1097\/01.mnh.0000186852.15889.1a","article-title":"The renal medullary endothelin system in control of sodium and water excretion and systemic blood pressure","volume":"15","author":"Kohan","year":"2006","journal-title":"Curr. Opin. Nephrol. Hypertens."},{"issue":"5","key":"10.1016\/j.lfs.2016.02.093_bb0130","doi-asserted-by":"crossref","first-page":"F1205","DOI":"10.1152\/ajprenal.00578.2007","article-title":"Renal medullary ETB receptors produce diuresis and natriuresis via NOS1","volume":"294","author":"Nakano","year":"2008","journal-title":"Am. J. Physiol. Ren. Physiol."},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0135","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1111\/j.1476-5381.2012.01922.x","article-title":"ET-1 actions in the kidney: evidence for sex differences","volume":"168","author":"Kittikulsuth","year":"2013","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.lfs.2016.02.093_bb0140","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1159\/000328696","article-title":"Endothelin in renal inflammation and hypertension","volume":"172","author":"Saleh","year":"2011","journal-title":"Contrib. Nephrol."},{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0145","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1165\/rcmb.2010-0506OC","article-title":"Endothelin-1, the unfolded protein response, and persistent inflammation: role of pulmonary artery smooth muscle cells","volume":"46","author":"Yeager","year":"2012","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0150","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/s00005-014-0310-1","article-title":"The role of endothelin-1 and endothelin receptor antagonists in inflammatory response and sepsis","volume":"63","author":"Kowalczyk","year":"2015","journal-title":"Arch. Immunol. Ther. Exp."},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0155","doi-asserted-by":"crossref","first-page":"R107","DOI":"10.1152\/ajpregu.00184.2013","article-title":"Does endoplasmic reticulum stress mediate endothelin-1-induced renal inflammation?","volume":"305","author":"De Miguel","year":"2013","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"issue":"5","key":"10.1016\/j.lfs.2016.02.093_bb0160","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1053\/he.2000.6596","article-title":"Production and release of endothelin-1 from the gut and spleen in portal hypertension due to cirrhosis","volume":"31","author":"Nagasue","year":"2000","journal-title":"Hepatology"},{"issue":"12","key":"10.1016\/j.lfs.2016.02.093_bb0165","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1002\/bjs.9622","article-title":"Effect of laparoscopic splenectomy on portal haemodynamics in patients with liver cirrhosis and portal hypertension","volume":"101","author":"Kawanaka","year":"2014","journal-title":"Br. J. Surg."},{"issue":"6","key":"10.1016\/j.lfs.2016.02.093_bb0170","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1161\/HYPERTENSIONAHA.108.120881","article-title":"Hypertension in response to chronic reductions in uterine perfusion in pregnant rats: effect of tumor necrosis factor-alpha blockade","volume":"52","author":"LaMarca","year":"2008","journal-title":"Hypertension"},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0175","doi-asserted-by":"crossref","first-page":"R144","DOI":"10.1152\/ajpregu.00049.2012","article-title":"Hypertension in response to CD4(+) T cells from reduced uterine perfusion pregnant rats is associated with activation of the endothelin-1 system","volume":"303","author":"Wallace","year":"2012","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0180","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1160\/TH13-10-0832","article-title":"Peri-interventional endothelin \u2013 a receptor blockade improves long-term outcome in patients with ST-elevation acute myocardial infarction","volume":"112","author":"Adlbrecht","year":"2014","journal-title":"Thromb. Haemost."},{"issue":"4","key":"10.1016\/j.lfs.2016.02.093_bb0185","doi-asserted-by":"crossref","first-page":"285","DOI":"10.2169\/internalmedicine.40.285","article-title":"Endothelin in renal diseases and cardiovascular remodeling in renal failure","volume":"40","author":"Orth","year":"2001","journal-title":"Intern. Med."},{"issue":"5","key":"10.1016\/j.lfs.2016.02.093_bb0190","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1161\/HYPERTENSIONAHA.110.156570","article-title":"Endothelin-1 increases glomerular permeability and inflammation independent of blood pressure in the rat","volume":"56","author":"Saleh","year":"2010","journal-title":"Hypertension"},{"issue":"12","key":"10.1016\/j.lfs.2016.02.093_bb0195","doi-asserted-by":"crossref","first-page":"2187","DOI":"10.1681\/ASN.2010020193","article-title":"ETA activation mediates angiotensin II-induced infiltration of renal cortical T cells","volume":"22","author":"Boesen","year":"2011","journal-title":"J. Am. Soc. Nephrol."},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0200","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1024\/0301-1526\/a000337","article-title":"In arterial occlusive disease autoantibodies against ETAR and AT(1)R correlate with each other but are not associated with classical cardiovascular risk factors","volume":"43","author":"Albert","year":"2014","journal-title":"Vasa"},{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0205","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1161\/HYPERTENSIONAHA.109.140459","article-title":"Extracellular signal-regulated kinase 1\/2 activation, via downregulation of mitogen-activated protein kinase phosphatase 1, mediates sex differences in desoxycorticosterone acetate-salt hypertension vascular reactivity","volume":"55","author":"Giachini","year":"2010","journal-title":"Hypertension"},{"issue":"3","key":"10.1016\/j.lfs.2016.02.093_bb0210","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1517\/14728222.12.3.327","article-title":"Therapeutic targets in hypertension: is there a place for antagonists of the most potent vasoconstrictors?","volume":"12","author":"Giachini","year":"2008","journal-title":"Expert Opin. Ther. Targets"},{"issue":"2 Pt 1","key":"10.1016\/j.lfs.2016.02.093_bb0215","first-page":"E258","article-title":"Neonatal gonadal hormones and blood pressure in the spontaneously hypertensive rat","volume":"247","author":"Cambotti","year":"1984","journal-title":"Am. J. Physiol."},{"issue":"1 Pt 2","key":"10.1016\/j.lfs.2016.02.093_bb0220","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1161\/01.HYP.29.1.494","article-title":"Gonadal hormones modulate deoxycorticosterone-salt hypertension in male and female rats","volume":"29","author":"Crofton","year":"1997","journal-title":"Hypertension"},{"issue":"3","key":"10.1016\/j.lfs.2016.02.093_bb0225","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1113\/EP085146","article-title":"Sex differences and blood pressure regulation in humans","volume":"101","author":"Joyner","year":"2016","journal-title":"Exp. Physiol."},{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0230","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1097\/MNH.0b013e328011d7f6","article-title":"Gonadal steroids, salt-sensitivity and renal function","volume":"16","author":"Pechere-Bertschi","year":"2007","journal-title":"Curr. Opin. Nephrol. Hypertens."},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0235","doi-asserted-by":"crossref","first-page":"158","DOI":"10.7326\/0003-4819-107-2-158","article-title":"Disparate cardiovascular findings in men and women with essential hypertension","volume":"107","author":"Messerli","year":"1987","journal-title":"Ann. Intern. Med."},{"issue":"5","key":"10.1016\/j.lfs.2016.02.093_bb0240","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1161\/01.HYP.0000099241.53121.7F","article-title":"Role of androgens in mediating renal injury in aging SHR","volume":"42","author":"Fortepiani","year":"2003","journal-title":"Hypertension"},{"issue":"5","key":"10.1016\/j.lfs.2016.02.093_bb0245","doi-asserted-by":"crossref","first-page":"918","DOI":"10.1161\/01.HYP.0000124670.03674.15","article-title":"Novel mechanisms responsible for postmenopausal hypertension","volume":"43","author":"Reckelhoff","year":"2004","journal-title":"Hypertension"},{"issue":"3","key":"10.1016\/j.lfs.2016.02.093_bb0250","doi-asserted-by":"crossref","first-page":"F365","DOI":"10.1152\/ajprenal.2001.280.3.F365","article-title":"Estrogen-induced cardiorenal protection: potential cellular, biochemical, and molecular mechanisms","volume":"280","author":"Dubey","year":"2001","journal-title":"Am. J. Physiol. Ren. Physiol."},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0255","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1161\/01.HYP.0000172945.06681.a4","article-title":"Sex hormones as potential modulators of vascular function in hypertension","volume":"46","author":"Khalil","year":"2005","journal-title":"Hypertension"},{"issue":"9","key":"10.1016\/j.lfs.2016.02.093_bb0260","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1590\/S0100-879X2003000900002","article-title":"Effects of estrogen on the vascular system","volume":"36","author":"Tostes","year":"2003","journal-title":"Braz. J. Med. Biol. Res."},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0265","doi-asserted-by":"crossref","first-page":"F399","DOI":"10.1152\/ajprenal.00195.2004","article-title":"17beta-Estradiol replacement improves renal function and pathology associated with diabetic nephropathy","volume":"288","author":"Mankhey","year":"2005","journal-title":"Am. J. Physiol. Ren. Physiol."},{"issue":"8","key":"10.1016\/j.lfs.2016.02.093_bb0270","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1007\/s11906-014-0458-4","article-title":"Yes! Sex matters: sex, the brain and blood pressure","volume":"16","author":"Hay","year":"2014","journal-title":"Curr. Hypertens. Rep."},{"issue":"7","key":"10.1016\/j.lfs.2016.02.093_bb0275","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1042\/CS20130140","article-title":"Sex and gender differences in control of blood pressure","volume":"125","author":"Maranon","year":"2013","journal-title":"Clin. Sci. (Lond.)"},{"issue":"4","key":"10.1016\/j.lfs.2016.02.093_bb0280","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1089\/jwh.2009.1407","article-title":"Gender-related differences in adolescent hypertension and in target organ effects","volume":"19","author":"Juhasz","year":"2010","journal-title":"J. Women's Health (Larchmt)"},{"issue":"6","key":"10.1016\/j.lfs.2016.02.093_bb0285","doi-asserted-by":"crossref","first-page":"429","DOI":"10.7326\/0003-4819-118-6-199303150-00006","article-title":"Influence of sex hormones on plasma endothelin levels","volume":"118","author":"Polderman","year":"1993","journal-title":"Ann. Intern. Med."},{"issue":"4 Pt 1","key":"10.1016\/j.lfs.2016.02.093_bb0290","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1016\/0002-8703(92)90734-D","article-title":"Age- and sex-related variation of plasma endothelin-1 concentration in normal and hypertensive subjects","volume":"123","author":"Miyauchi","year":"1992","journal-title":"Am. Heart J."},{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0295","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1152\/japplphysiol.01016.2002","article-title":"Aerobic exercise training reduces plasma endothelin-1 concentration in older women","volume":"95","author":"Maeda","year":"2003","journal-title":"J. Appl. Physiol. (1985)"},{"issue":"4","key":"10.1016\/j.lfs.2016.02.093_bb0300","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1161\/01.HYP.30.4.817","article-title":"Anatomic heterogeneity of vascular aging: role of nitric oxide and endothelin","volume":"30","author":"Barton","year":"1997","journal-title":"Hypertension"},{"issue":"1\u20132","key":"10.1016\/j.lfs.2016.02.093_bb0305","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0531-5565(96)00080-0","article-title":"Expression of endothelin, fibronectin, and mortalin as aging and mortality markers","volume":"32","author":"Kumazaki","year":"1997","journal-title":"Exp. Gerontol."},{"issue":"3","key":"10.1016\/j.lfs.2016.02.093_bb0310","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1006\/bbrc.2000.4180","article-title":"Increased expression of endothelin-1 and inducible nitric oxide synthase isoform II in aging arteries in vivo: implications for atherosclerosis","volume":"280","author":"Goettsch","year":"2001","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"3","key":"10.1016\/j.lfs.2016.02.093_bb0315","doi-asserted-by":"crossref","first-page":"R509","DOI":"10.1152\/ajpregu.00656.2009","article-title":"Endothelin in the female vasculature: a role in aging?","volume":"298","author":"Lekontseva","year":"2010","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0320","first-page":"89","article-title":"Sex hormones in the cardiovascular system","volume":"18","author":"dos Santos","year":"2014","journal-title":"Horm. Mol. Biol. Clin. Invest."},{"issue":"7","key":"10.1016\/j.lfs.2016.02.093_bb0325","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/j.metabol.2008.02.012","article-title":"Relationship between endogenous testosterone and cardiovascular risk in early postmenopausal women","volume":"57","author":"Maturana","year":"2008","journal-title":"Metabolism"},{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0330","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S0301-2115(97)00141-3","article-title":"Changes in plasma and amniotic fluid endothelin levels during pregnancy: facts or artefacts?","volume":"76","author":"Carbonne","year":"1998","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0335","first-page":"157","article-title":"Changes in maternal plasma levels of VEGF, bFGF, TGF-beta1, ET-1 and sKL during uncomplicated pregnancy, hypertensive pregnancy and gestational diabetes","volume":"20","author":"Lygnos","year":"2006","journal-title":"In Vivo"},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0340","doi-asserted-by":"crossref","first-page":"324","DOI":"10.3109\/14767058.2010.496502","article-title":"Maternal and fetal circulating sKL and ET-1 levels as function of normal labor at term","volume":"24","author":"Pappa","year":"2011","journal-title":"J. Matern. Fetal Neonatal Med."},{"issue":"6","key":"10.1016\/j.lfs.2016.02.093_bb0345","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1161\/HYPERTENSIONAHA.115.05267","article-title":"Association studies suggest a key role for endothelin-1 in the pathogenesis of preeclampsia and the accompanying renin-angiotensin-aldosterone system suppression","volume":"65","author":"Verdonk","year":"2015","journal-title":"Hypertension"},{"key":"10.1016\/j.lfs.2016.02.093_bb0350","first-page":"1","article-title":"Plasma markers of endothelial dysfunction in patients with hypertensive disorders of pregnancy: a pilot study in a South Indian population","author":"Vinayagam","year":"2015","journal-title":"J. Matern. Fetal Neonatal Med."},{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0355","doi-asserted-by":"crossref","first-page":"44e1","DOI":"10.1016\/j.ajog.2013.03.032","article-title":"Progesterone blunts vascular endothelial cell secretion of endothelin-1 in response to placental ischemia","volume":"209","author":"Kiprono","year":"2013","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"4","key":"10.1016\/j.lfs.2016.02.093_bb0360","doi-asserted-by":"crossref","first-page":"330e1","DOI":"10.1016\/j.ajog.2011.01.049","article-title":"Endothelin type A receptor antagonist attenuates placental ischemia-induced hypertension and uterine vascular resistance","volume":"204","author":"Tam Tam","year":"2011","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"10","key":"10.1016\/j.lfs.2016.02.093_bb0365","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1055\/s-2008-1073149","article-title":"Effects of the progestagen-only contraceptive implant Implanon on transforming growth factor beta1 and endothelin-1","volume":"40","author":"Merki-Feld","year":"2008","journal-title":"Horm. Metab. Res."},{"issue":"4","key":"10.1016\/j.lfs.2016.02.093_bb0370","doi-asserted-by":"crossref","first-page":"285","DOI":"10.7326\/0003-4819-128-4-199802150-00006","article-title":"The effect of estrogen replacement therapy on plasma nitric oxide and endothelin-1 levels in postmenopausal women","volume":"128","author":"Best","year":"1998","journal-title":"Ann. Intern. Med."},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0375","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/j.fertnstert.2008.06.049","article-title":"Effects of nonoral estradiol-micronized progesterone or low-dose oral estradiol-drospirenone therapy on metabolic variables and markers of endothelial function in early postmenopause","volume":"92","author":"Casanova","year":"2009","journal-title":"Fertil. Steril."},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0380","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.ejogrb.2008.10.007","article-title":"Short-term effects of two continuous combined oestrogen-progestogen therapies on several cardiovascular risk markers in healthy postmenopausal women: a randomised controlled trial","volume":"142","author":"de Kraker","year":"2009","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0385","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1111\/j.2042-7158.2011.01377.x","article-title":"Nicotine and vascular endothelial dysfunction in female ovariectomized rats: role of estrogen replacement therapy","volume":"64","author":"El-Seweidy","year":"2012","journal-title":"J. Pharm. Pharmacol."},{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0390","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1111\/j.1447-0756.2012.01969.x","article-title":"Effect of raloxifene and atorvastatin in atherosclerotic process in ovariectomized rats","volume":"39","author":"Cetinkaya Demir","year":"2013","journal-title":"J. Obstet. Gynaecol. Res."},{"issue":"9","key":"10.1016\/j.lfs.2016.02.093_bb0395","doi-asserted-by":"crossref","first-page":"1512","DOI":"10.1161\/hq0901.095565","article-title":"Randomized, double-blind, placebo-controlled study on effects of raloxifene and hormone replacement therapy on plasma no concentrations, endothelin-1 levels, and endothelium-dependent vasodilation in postmenopausal women","volume":"21","author":"Saitta","year":"2001","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0400","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1111\/j.1527-3466.2001.tb00183.x","article-title":"Cardiovascular effects of raloxifene hydrochloride","volume":"19","author":"Saitta","year":"2001","journal-title":"Cardiovasc. Drug Rev."},{"issue":"6","key":"10.1016\/j.lfs.2016.02.093_bb0405","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1080\/09513590410001729888","article-title":"Comparative vascular effects of hormone replacement therapy and raloxifene in women at increased cardiovascular risk","volume":"18","author":"Cerquetani","year":"2004","journal-title":"Gynecol. Endocrinol."},{"issue":"10","key":"10.1016\/j.lfs.2016.02.093_bb0410","doi-asserted-by":"crossref","first-page":"4666","DOI":"10.1210\/jcem.86.10.7904","article-title":"Increased endothelin-1 levels in women with polycystic ovary syndrome and the beneficial effect of metformin therapy","volume":"86","author":"Diamanti-Kandarakis","year":"2001","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"10","key":"10.1016\/j.lfs.2016.02.093_bb0415","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1111\/j.1365-2362.2006.01712.x","article-title":"Inflammatory and endothelial markers in women with polycystic ovary syndrome","volume":"36","author":"Diamanti-Kandarakis","year":"2006","journal-title":"Eur. J. Clin. Investig."},{"issue":"6","key":"10.1016\/j.lfs.2016.02.093_bb0420","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1093\/humupd\/dmr025","article-title":"Meta-analysis of cardiovascular disease risk markers in women with polycystic ovary syndrome","volume":"17","author":"Toulis","year":"2011","journal-title":"Hum. Reprod. Update"},{"issue":"4","key":"10.1016\/j.lfs.2016.02.093_bb0425","doi-asserted-by":"crossref","first-page":"292","DOI":"10.14310\/horm.2002.1320","article-title":"Strong and positive association of endothelin-1 with AGEs in PCOS: a causal relationship or a bystander?","volume":"10","author":"Christakou","year":"2011","journal-title":"Hormones (Athens)"},{"issue":"7","key":"10.1016\/j.lfs.2016.02.093_bb0430","doi-asserted-by":"crossref","first-page":"E818","DOI":"10.1152\/ajpendo.00343.2013","article-title":"Androgens influence microvascular dilation in PCOS through ET-A and ET-B receptors","volume":"305","author":"Wenner","year":"2013","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0435","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/j.1365-2605.2006.00706.x","article-title":"Testosterone replacement therapy in male hypogonadism is not associated with increase of endothelin-1 levels","volume":"30","author":"Kumanov","year":"2007","journal-title":"Int. J. Androl."},{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0440","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1006\/bbrc.1998.9409","article-title":"Estrogen attenuates endothelin-1 production by bovine endothelial cells via estrogen receptor","volume":"251","author":"Akishita","year":"1998","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"3","key":"10.1016\/j.lfs.2016.02.093_bb0445","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/S0008-6363(00)00046-8","article-title":"17Beta-estradiol modulates endothelin-1 expression and release in human endothelial cells","volume":"46","author":"Bilsel","year":"2000","journal-title":"Cardiovasc. Res."},{"issue":"4 Pt 2","key":"10.1016\/j.lfs.2016.02.093_bb0450","first-page":"H1962","article-title":"Gender and transcriptional regulation of NO synthase and ET-1 in porcine aortic endothelial cells","volume":"273","author":"Wang","year":"1997","journal-title":"Am. J. Physiol."},{"issue":"3","key":"10.1016\/j.lfs.2016.02.093_bb0455","doi-asserted-by":"crossref","first-page":"H1254","DOI":"10.1152\/ajpheart.00723.2003","article-title":"17beta-estradiol inhibits cyclic strain-induced endothelin-1 gene expression within vascular endothelial cells","volume":"287","author":"Juan","year":"2004","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"2 Pt 2","key":"10.1016\/j.lfs.2016.02.093_bb0460","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1161\/01.HYP.37.2.640","article-title":"Estradiol metabolites inhibit endothelin synthesis by an estrogen receptor-independent mechanism","volume":"37","author":"Dubey","year":"2001","journal-title":"Hypertension"},{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0465","first-page":"27","article-title":"17beta-estradiol downregulates angiotensin-II-induced endothelin-1 gene expression in rat aortic smooth muscle cells","volume":"11","author":"Hong","year":"2004","journal-title":"J. Biomed. Sci."},{"issue":"5","key":"10.1016\/j.lfs.2016.02.093_bb0470","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1136\/hrt.2003.031898","article-title":"Inhibition of angiotensin II induced endothelin-1 gene expression by 17-beta-oestradiol in rat cardiac fibroblasts","volume":"91","author":"Chao","year":"2005","journal-title":"Heart"},{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0475","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/0021-9150(96)05836-4","article-title":"Estrogen inhibits endothelin-1 production and c-fos gene expression in rat aorta","volume":"125","author":"Akishita","year":"1996","journal-title":"Atherosclerosis"},{"issue":"6","key":"10.1016\/j.lfs.2016.02.093_bb0480","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1016\/j.peptides.2008.02.003","article-title":"Regulation of endothelin-1 release from human endothelial cells by sex steroids and angiotensin-II","volume":"29","author":"Pearson","year":"2008","journal-title":"Peptides"},{"issue":"3","key":"10.1016\/j.lfs.2016.02.093_bb0485","first-page":"347","article-title":"[Role of NO signal pathway in the inhibitory of 17beta-estradiol on the production of endothelin-1 in vascular smooth muscle cells]","volume":"23","author":"Tan","year":"2007","journal-title":"Zhongguo Ying Yong Sheng Li Xue Za Zhi"},{"issue":"3 Pt 2","key":"10.1016\/j.lfs.2016.02.093_bb0490","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1161\/01.HYP.38.3.692","article-title":"Ovarian hormones modulate endothelin-1 vascular reactivity and mRNA expression in DOCA-salt hypertensive rats","volume":"38","author":"David","year":"2001","journal-title":"Hypertension"},{"issue":"9","key":"10.1016\/j.lfs.2016.02.093_bb0495","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1590\/S0100-879X2002000900006","article-title":"Gender differences in vascular expression of endothelin and ET(A)\/ET(B) receptors, but not in calcium handling mechanisms, in deoxycorticosterone acetate-salt hypertension","volume":"35","author":"David","year":"2002","journal-title":"Braz. J. Med. Biol. Res."},{"issue":"21","key":"10.1016\/j.lfs.2016.02.093_bb0500","doi-asserted-by":"crossref","first-page":"2665","DOI":"10.1016\/S0024-3205(03)00605-2","article-title":"Mechanisms of 17beta-estradiol on the production of ET-1 in ovariectomized rats","volume":"73","author":"Tan","year":"2003","journal-title":"Life Sci."},{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0505","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1177\/002580247501500103","article-title":"Drugs and sport","volume":"15","author":"Williams","year":"1975","journal-title":"Med. Sci. Law"},{"issue":"23","key":"10.1016\/j.lfs.2016.02.093_bb0510","doi-asserted-by":"crossref","first-page":"2973","DOI":"10.1016\/j.lfs.2003.05.001","article-title":"Vascular ECE-1 mRNA expression decreases in response to estrogens","volume":"73","author":"Rodrigo","year":"2003","journal-title":"Life Sci."},{"issue":"1\u20132","key":"10.1016\/j.lfs.2016.02.093_bb0515","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.cca.2007.06.003","article-title":"Endothelin-converting enzyme-1b C-338A polymorphism is associated with the increased risk of coronary artery disease in Chinese population","volume":"384","author":"Wang","year":"2007","journal-title":"Clin. Chim. Acta"},{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0520","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.mvr.2009.03.001","article-title":"C-338A polymorphism of the endothelin-converting enzyme-1 gene and the susceptibility to carotid atherosclerosis","volume":"78","author":"Jin","year":"2009","journal-title":"Microvasc. Res."},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0525","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/s12031-013-0100-y","article-title":"Association of endothelin-converting enzyme-1b C-338A polymorphism with increased risk of ischemic stroke in Chinese Han population","volume":"51","author":"Li","year":"2013","journal-title":"J. Mol. Neurosci."},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0530","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/S0022-3565(24)37427-0","article-title":"Gender differences in the expression of endothelin receptors in human saphenous veins in vitro","volume":"285","author":"Ergul","year":"1998","journal-title":"J. Pharmacol. Exp. Ther."},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0535","doi-asserted-by":"crossref","first-page":"R261","DOI":"10.1152\/ajpregu.00626.2009","article-title":"Sex differences in endothelin-1-mediated vasoconstrictor tone in middle-aged and older adults","volume":"298","author":"Stauffer","year":"2010","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0540","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1038\/sj.bjp.0705409","article-title":"17 Beta-estradiol regulates the expression of endothelin receptor type B in the heart","volume":"140","author":"Nuedling","year":"2003","journal-title":"Br. J. Pharmacol."},{"issue":"3","key":"10.1016\/j.lfs.2016.02.093_bb0545","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1080\/09513590802549833","article-title":"Hormone therapy modulates ET(A) mRNA expression in the aorta of ovariectomised New Zealand White rabbits","volume":"25","author":"Pedersen","year":"2009","journal-title":"Gynecol. Endocrinol."},{"issue":"3","key":"10.1016\/j.lfs.2016.02.093_bb0550","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1097\/gme.0b013e318156f803","article-title":"Progestins oppose the effects of estradiol on the endothelin-1 receptor type B in coronary arteries from ovariectomized hyperlipidemic rabbits","volume":"15","author":"Pedersen","year":"2008","journal-title":"Menopause"},{"key":"10.1016\/j.lfs.2016.02.093_bb0555","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1540\/jsmr.50.85","article-title":"Orchidectomy enhances the expression of endothelin-1 and ETB receptors in rat portal vein","volume":"50","author":"Rossignoli Pde","year":"2014","journal-title":"J. Smooth Muscle Res."},{"issue":"4","key":"10.1016\/j.lfs.2016.02.093_bb0560","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1111\/j.1440-1681.2007.04580.x","article-title":"Involvement of the endothelin ET(B) receptor in gender differences in deoxycorticosterone acetate-salt-induced hypertension","volume":"34","author":"Kawanishi","year":"2007","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"issue":"3 Pt 2","key":"10.1016\/j.lfs.2016.02.093_bb0565","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1161\/01.HYP.0000048193.85814.78","article-title":"Gender differences in ET and NOS systems in ETB receptor-deficient rats: effect of a high salt diet","volume":"41","author":"Taylor","year":"2003","journal-title":"Hypertension"},{"issue":"6","key":"10.1016\/j.lfs.2016.02.093_bb0570","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1111\/bph.12225","article-title":"Enhanced endothelin receptor type B-mediated vasodilation and underlying [Ca(2)(+)]i in mesenteric microvessels of pregnant rats","volume":"169","author":"Mazzuca","year":"2013","journal-title":"Br. J. Pharmacol."},{"issue":"3","key":"10.1016\/j.lfs.2016.02.093_bb0575","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1161\/HYPERTENSIONAHA.113.01449","article-title":"Gestational hypoxia induces preeclampsia-like symptoms via heightened endothelin-1 signaling in pregnant rats","volume":"62","author":"Zhou","year":"2013","journal-title":"Hypertension"},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0580","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1161\/HYPERTENSIONAHA.111.172734","article-title":"Sex differences in renal medullary endothelin receptor function in angiotensin II hypertensive rats","volume":"58","author":"Kittikulsuth","year":"2011","journal-title":"Hypertension"},{"issue":"6","key":"10.1016\/j.lfs.2016.02.093_bb0585","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1111\/1440-1681.12084","article-title":"Endothelin ET(B) receptors contribute to sex differences in blood pressure elevation in angiotensin II hypertensive rats on a high-salt diet","volume":"40","author":"Kittikulsuth","year":"2013","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"issue":"3","key":"10.1016\/j.lfs.2016.02.093_bb0590","doi-asserted-by":"crossref","DOI":"10.14814\/phy2.12326","article-title":"High salt diet increases the pressor response to stress in female, but not male ETB-receptor-deficient rats","volume":"3","author":"Speed","year":"2015","journal-title":"Physiol. Rep."},{"issue":"5","key":"10.1016\/j.lfs.2016.02.093_bb0595","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.1152\/jappl.2001.91.5.2407","article-title":"Selected contribution: Gender differences in the endothelin-B receptor contribution to basal cutaneous vascular tone in humans","volume":"91","author":"Kellogg","year":"2001","journal-title":"J. Appl. Physiol. (1985)"},{"issue":"4","key":"10.1016\/j.lfs.2016.02.093_bb0600","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0062698","article-title":"Male-female differences in upregulation of vasoconstrictor responses in human cerebral arteries","volume":"8","author":"Ahnstedt","year":"2013","journal-title":"PLoS One"},{"issue":"5 Suppl. 1","key":"10.1016\/j.lfs.2016.02.093_bb0605","doi-asserted-by":"crossref","first-page":"S99","DOI":"10.1097\/00005344-200036051-00032","article-title":"Gender differences in vascular reactivity to endothelin-1 in deoxycorticosterone-salt hypertensive rats","volume":"36","author":"Tostes","year":"2000","journal-title":"J. Cardiovasc. Pharmacol."},{"issue":"5","key":"10.1016\/j.lfs.2016.02.093_bb0610","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1038\/sj.bjp.0703389","article-title":"Deoxycorticosterone acetate-salt hypertensive rats display gender-related differences in ET(B) receptor-mediated vascular responses","volume":"130","author":"Tostes Passaglia","year":"2000","journal-title":"Br. J. Pharmacol."},{"issue":"5","key":"10.1016\/j.lfs.2016.02.093_bb0615","first-page":"807","article-title":"Influence of sex on the reactivity to endothelin-1 and noradrenaline in spontaneously hypertensive rats","volume":"13","author":"Fortes","year":"1991","journal-title":"Clin. Exp. Hypertens. A"},{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0620","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1152\/jappl.2001.90.1.216","article-title":"Interaction of gender and exercise training: vasomotor reactivity of porcine skeletal muscle arteries","volume":"90","author":"Laughlin","year":"2001","journal-title":"J. Appl. Physiol. (1985)"},{"issue":"3","key":"10.1016\/j.lfs.2016.02.093_bb0625","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1152\/jappl.1999.87.3.1172","article-title":"Endothelin-1 sensitivity of porcine coronary arteries is reduced by exercise training and is gender dependent","volume":"87","author":"Jones","year":"1999","journal-title":"J. Appl. Physiol. (1985)"},{"issue":"3","key":"10.1016\/j.lfs.2016.02.093_bb0630","first-page":"705","article-title":"Estrogen-induced improvement in coronary flow responses during atrial pacing in relation to endothelin-1 levels in postmenopausal women without coronary disease","volume":"4","author":"Kallikazaros","year":"2008","journal-title":"Vasc. Health Risk Manag."},{"issue":"3 Pt 2","key":"10.1016\/j.lfs.2016.02.093_bb0635","first-page":"H1117","article-title":"Effects of 17 beta-estradiol on coronary microvascular responses to endothelin-1","volume":"271","author":"Lamping","year":"1996","journal-title":"Am. J. Physiol."},{"issue":"10","key":"10.1016\/j.lfs.2016.02.093_bb0640","doi-asserted-by":"crossref","first-page":"3626","DOI":"10.1161\/01.CIR.96.10.3626","article-title":"Physiological concentrations of estradiol attenuate endothelin 1-induced coronary vasoconstriction in vivo","volume":"96","author":"Sudhir","year":"1997","journal-title":"Circulation"},{"issue":"7","key":"10.1016\/j.lfs.2016.02.093_bb0645","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1038\/sj.bjp.0703164","article-title":"Differential effects of 17beta-estradiol and testosterone on the contractile responses of porcine coronary arteries","volume":"129","author":"Teoh","year":"2000","journal-title":"Br. J. Pharmacol."},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0650","doi-asserted-by":"crossref","first-page":"137","DOI":"10.3109\/10623320109165322","article-title":"Gender-related differences in proliferative responses of vascular smooth muscle cells to endothelin-1","volume":"8","author":"Antoniucci","year":"2001","journal-title":"Endothelium"},{"issue":"2\u20134","key":"10.1016\/j.lfs.2016.02.093_bb0655","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1159\/000085982","article-title":"A new model for determining the influence of age and sex on functional recovery following hypoxic-ischemic brain damage","volume":"27","author":"Yager","year":"2005","journal-title":"Dev. Neurosci."},{"issue":"12","key":"10.1016\/j.lfs.2016.02.093_bb0660","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1042\/CS20120700","article-title":"Testosterone and beta-oestradiol prevent inward remodelling of rat small mesenteric arteries: role of NO and transglutaminase","volume":"124","author":"del Campo","year":"2013","journal-title":"Clin. Sci. (Lond.)"},{"issue":"4","key":"10.1016\/j.lfs.2016.02.093_bb0665","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1161\/HYPERTENSIONAHA.107.107938","article-title":"Deoxycorticosterone acetate-salt mice exhibit blood pressure-independent sexual dimorphism","volume":"51","author":"Karatas","year":"2008","journal-title":"Hypertension"},{"issue":"3","key":"10.1016\/j.lfs.2016.02.093_bb0670","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1161\/HYPERTENSIONAHA.110.166157","article-title":"Estrogen receptor-beta signals left ventricular hypertrophy sex differences in normotensive deoxycorticosterone acetate-salt mice","volume":"57","author":"Gurgen","year":"2011","journal-title":"Hypertension"},{"issue":"4","key":"10.1016\/j.lfs.2016.02.093_bb0675","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1161\/01.HYP.0000088363.65943.6C","article-title":"ETA receptor blockade decreases vascular superoxide generation in DOCA-salt hypertension","volume":"42","author":"Callera","year":"2003","journal-title":"Hypertension"},{"issue":"4","key":"10.1016\/j.lfs.2016.02.093_bb0680","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1161\/01.HYP.0000117296.30296.14","article-title":"ETA receptor mediates altered leukocyte-endothelial cell interaction and adhesion molecules expression in DOCA-salt rats","volume":"43","author":"Callera","year":"2004","journal-title":"Hypertension"},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0685","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1161\/HYPERTENSIONAHA.108.123687","article-title":"Contribution of endothelin A receptors in endothelin 1-dependent natriuresis in female rats","volume":"53","author":"Nakano","year":"2009","journal-title":"Hypertension"},{"issue":"8","key":"10.1016\/j.lfs.2016.02.093_bb0690","doi-asserted-by":"crossref","first-page":"F1099","DOI":"10.1152\/ajprenal.00400.2013","article-title":"Sex differences in ET-1 receptor expression and Ca2+ signaling in the IMCD","volume":"305","author":"Jin","year":"2013","journal-title":"Am. J. Physiol. Ren. Physiol."},{"issue":"4","key":"10.1016\/j.lfs.2016.02.093_bb0695","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1111\/j.1523-1755.2005.00589.x","article-title":"Gender hormones and the progression of experimental polycystic kidney disease","volume":"68","author":"Stringer","year":"2005","journal-title":"Kidney Int."},{"key":"10.1016\/j.lfs.2016.02.093_bb0700","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/2047-783X-14-2-55","article-title":"Renal phenotype of ET-1 transgenic mice is modulated by androgens","volume":"14","author":"Kalk","year":"2009","journal-title":"Eur. J. Med. Res."},{"issue":"4","key":"10.1016\/j.lfs.2016.02.093_bb0705","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1111\/j.1523-1755.2002.kid590.x","article-title":"Sexual dimorphism in renal ischemia-reperfusion injury in rats: possible role of endothelin","volume":"62","author":"Muller","year":"2002","journal-title":"Kidney Int."},{"issue":"3","key":"10.1016\/j.lfs.2016.02.093_bb0710","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1111\/1744-9987.12101","article-title":"Role of testosterone in the pathogenesis, progression, prognosis and comorbidity of men with chronic kidney disease","volume":"18","author":"Dousdampanis","year":"2014","journal-title":"Ther. Apher. Dial."},{"issue":"Suppl. 48","key":"10.1016\/j.lfs.2016.02.093_bb0715","doi-asserted-by":"crossref","first-page":"434S","DOI":"10.1042\/CS103S434S","article-title":"Oestrogen protects against ischaemic acute renal failure in rats by suppressing renal endothelin-1 overproduction","volume":"103","author":"Takaoka","year":"2002","journal-title":"Clin. Sci. (Lond.)"},{"issue":"Suppl. 1","key":"10.1016\/j.lfs.2016.02.093_bb0720","doi-asserted-by":"crossref","first-page":"S459","DOI":"10.1097\/01.fjc.0000166315.38258.e1","article-title":"Involvement of nitric oxide in the suppressive effect of 17beta-estradiol on endothelin-1 overproduction in ischemic acute renal failure","volume":"44","author":"Shibata","year":"2004","journal-title":"J. Cardiovasc. Pharmacol."},{"issue":"5","key":"10.1016\/j.lfs.2016.02.093_bb0725","doi-asserted-by":"crossref","first-page":"H2061","DOI":"10.1152\/ajpheart.00707.2008","article-title":"Role of estrogen receptor subtypes in estrogen-induced organ-specific vasorelaxation after trauma-hemorrhage","volume":"295","author":"Ba","year":"2008","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.lfs.2016.02.093_bb0730","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2016.01.010","article-title":"Ovarian hormones modulate endothelin A and B receptor expression","author":"Gohar","year":"2016","journal-title":"Life Sci."},{"issue":"6","key":"10.1016\/j.lfs.2016.02.093_bb0735","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1210\/me.2012-1334","article-title":"Control of endothelin-a receptor expression by progesterone is enhanced by synergy with Gata2","volume":"27","author":"Zhang","year":"2013","journal-title":"Mol. Endocrinol."},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0740","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1038\/ki.2014.17","article-title":"Advances in the pathophysiology of pre-eclampsia and related podocyte injury","volume":"86","author":"Craici","year":"2014","journal-title":"Kidney Int."},{"issue":"5 Suppl. 1","key":"10.1016\/j.lfs.2016.02.093_bb0745","doi-asserted-by":"crossref","first-page":"S102","DOI":"10.1097\/00005344-200036051-00033","article-title":"Gender differences in hemodynamic responses to endothelin-1","volume":"36","author":"Tatchum-Talom","year":"2000","journal-title":"J. Cardiovasc. Pharmacol."},{"issue":"5\u20136","key":"10.1016\/j.lfs.2016.02.093_bb0750","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1159\/000351704","article-title":"Pharmacokinetics of macitentan in Caucasian and Japanese subjects: the influence of ethnicity and sex","volume":"91","author":"Bruderer","year":"2013","journal-title":"Pharmacology"},{"issue":"3","key":"10.1016\/j.lfs.2016.02.093_bb0755","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1081\/CEH-100102662","article-title":"Obese female SHHF\/Mcc-fa(cp) rats resist antihypertensive effects of renin-angiotensin system inhibition","volume":"23","author":"Sharkey","year":"2001","journal-title":"Clin. Exp. Hypertens."},{"issue":"5","key":"10.1016\/j.lfs.2016.02.093_bb0760","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1002\/clc.4960270510","article-title":"Gender-specific association between preproendothelin-1 genotype and reduction of systolic blood pressure during antihypertensive treatment \u2013 results from the Swedish Irbesartan Left Ventricular Hypertrophy Investigation versus Atenolol (SILVHIA)","volume":"27","author":"Hallberg","year":"2004","journal-title":"Clin. Cardiol."},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0765","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.lfs.2014.01.009","article-title":"Vasoprotective effects of an endothelin receptor antagonist in ovariectomized female rats","volume":"118","author":"Kitada","year":"2014","journal-title":"Life Sci."},{"issue":"12","key":"10.1016\/j.lfs.2016.02.093_bb0770","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1056\/NEJM199803193381202","article-title":"The effect of an endothelin-receptor antagonist, bosentan, on blood pressure in patients with essential hypertension. Bosentan Hypertension Investigators","volume":"338","author":"Krum","year":"1998","journal-title":"N. Engl. J. Med."},{"issue":"7 Pt 1","key":"10.1016\/j.lfs.2016.02.093_bb0775","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/S0895-7061(02)02933-3","article-title":"Darusentan: an effective endothelinA receptor antagonist for treatment of hypertension","volume":"15","author":"Nakov","year":"2002","journal-title":"Am. J. Hypertens."},{"issue":"4","key":"10.1016\/j.lfs.2016.02.093_bb0780","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1161\/HYPERTENSIONAHA.110.167486","article-title":"Selective endothelin-A receptor antagonism reduces proteinuria, blood pressure, and arterial stiffness in chronic proteinuric kidney disease","volume":"57","author":"Dhaun","year":"2011","journal-title":"Hypertension"},{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0785","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1161\/HYPERTENSIONAHA.109.132670","article-title":"Blood pressure-independent reduction in proteinuria and arterial stiffness after acute endothelin-a receptor antagonism in chronic kidney disease","volume":"54","author":"Dhaun","year":"2009","journal-title":"Hypertension"},{"issue":"3","key":"10.1016\/j.lfs.2016.02.093_bb0790","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1681\/ASN.2008050482","article-title":"Avosentan reduces albumin excretion in diabetics with macroalbuminuria","volume":"20","author":"Wenzel","year":"2009","journal-title":"J. Am. Soc. Nephrol."},{"issue":"4","key":"10.1016\/j.lfs.2016.02.093_bb0795","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1681\/ASN.2010080869","article-title":"Addition of atrasentan to renin-angiotensin system blockade reduces albuminuria in diabetic nephropathy","volume":"22","author":"Kohan","year":"2011","journal-title":"J. Am. Soc. Nephrol."},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0800","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1124\/jpet.113.205286","article-title":"Myocardial, smooth muscle, nephron, and collecting duct gene targeting reveals the organ sites of endothelin A receptor antagonist fluid retention","volume":"346","author":"Stuart","year":"2013","journal-title":"J. Pharmacol. Exp. Ther."},{"issue":"9699","key":"10.1016\/j.lfs.2016.02.093_bb0805","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1016\/S0140-6736(09)61500-2","article-title":"A selective endothelin-receptor antagonist to reduce blood pressure in patients with treatment-resistant hypertension: a randomised, double-blind, placebo-controlled trial","volume":"374","author":"Weber","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.lfs.2016.02.093_bb0810","article-title":"The therapeutic potential of endothelin receptor antagonism in kidney disease","author":"Czopek","year":"2015","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"issue":"6","key":"10.1016\/j.lfs.2016.02.093_bb0815","doi-asserted-by":"crossref","first-page":"1171","DOI":"10.3390\/jcm4061171","article-title":"Endothelin Blockade in Diabetic Kidney Disease","volume":"4","author":"Anguiano","year":"2015","journal-title":"J. Clin. Med."},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0820","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.semnephrol.2015.03.001","article-title":"Endothelin antagonism and hypertension: an evolving target","volume":"35","author":"Laffin","year":"2015","journal-title":"Semin. Nephrol."},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0825","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.semnephrol.2015.02.002","article-title":"Endothelin receptors and their antagonists","volume":"35","author":"Maguire","year":"2015","journal-title":"Semin. Nephrol."},{"issue":"5","key":"10.1016\/j.lfs.2016.02.093_bb0830","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/s40264-015-0275-y","article-title":"Comparative safety and tolerability of endothelin receptor antagonists in pulmonary arterial hypertension","volume":"38","author":"Aversa","year":"2015","journal-title":"Drug Saf."},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0835","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1097\/00004356-197905000-00008","article-title":"Are poor living conditions in childhood and adolescence and important risk factor for arteriosclerotic heart disease?","volume":"2","author":"Forsdahl","year":"1979","journal-title":"Int. J. Rehabil. Res."},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0840","first-page":"91","article-title":"Are poor living conditions in childhood and adolescence an important risk factor for arteriosclerotic heart disease?","volume":"31","author":"Forsdahl","year":"1977","journal-title":"Br. J. Prev. Soc. Med."},{"issue":"6673","key":"10.1016\/j.lfs.2016.02.093_bb0845","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1136\/bmj.298.6673.564","article-title":"Growth in utero, blood pressure in childhood and adult life, and mortality from cardiovascular disease","volume":"298","author":"Barker","year":"1989","journal-title":"BMJ"},{"issue":"6641","key":"10.1016\/j.lfs.2016.02.093_bb0850","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1136\/bmj.297.6641.134-b","article-title":"Low birth weight and hypertension","volume":"297","author":"Barker","year":"1988","journal-title":"BMJ"},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0855","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1111\/apha.12206","article-title":"Sex differences in the developmental programming of hypertension","volume":"210","author":"Ojeda","year":"2014","journal-title":"Acta Physiol. (Oxf.)"},{"issue":"3","key":"10.1016\/j.lfs.2016.02.093_bb0860","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1055\/s-0031-1275520","article-title":"The early origins of cardiovascular health and disease: who, when, and how","volume":"29","author":"Rueda-Clausen","year":"2011","journal-title":"Semin. Reprod. Med."},{"issue":"4","key":"10.1016\/j.lfs.2016.02.093_bb0865","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1161\/HYPERTENSIONAHA.113.01516","article-title":"Prenatal hypoxia causes long-term alterations in vascular endothelin-1 function in aged male, but not female, offspring","volume":"62","author":"Bourque","year":"2013","journal-title":"Hypertension"},{"issue":"8","key":"10.1016\/j.lfs.2016.02.093_bb0870","doi-asserted-by":"crossref","first-page":"R581","DOI":"10.1152\/ajpregu.00579.2012","article-title":"Antenatal betamethasone has a sex-dependent effect on the in vivo response to endothelin in adult sheep","volume":"304","author":"Lee","year":"2013","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0875","doi-asserted-by":"crossref","first-page":"R185","DOI":"10.1152\/ajpregu.00333.2009","article-title":"Early life stress downregulates endothelin receptor expression and enhances acute stress-mediated blood pressure responses in adult rats","volume":"299","author":"Loria","year":"2010","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0880","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1161\/HYPERTENSIONAHA.110.152629","article-title":"Endothelin activation of reactive oxygen species mediates stress-induced pressor response in Dahl salt-sensitive prehypertensive rats","volume":"56","author":"D'Angelo","year":"2010","journal-title":"Hypertension"},{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0885","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1161\/HYPERTENSIONAHA.113.02755","article-title":"Adverse childhood experiences are associated with detrimental hemodynamics and elevated circulating endothelin-1 in adolescents and young adults","volume":"64","author":"Su","year":"2014","journal-title":"Hypertension"},{"issue":"5","key":"10.1016\/j.lfs.2016.02.093_bb0890","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1002709","article-title":"The number of x chromosomes causes sex differences in adiposity in mice","volume":"8","author":"Chen","year":"2012","journal-title":"PLoS Genet."},{"issue":"23","key":"10.1016\/j.lfs.2016.02.093_bb0895","doi-asserted-by":"crossref","first-page":"17271","DOI":"10.1074\/jbc.R110.113175","article-title":"Obesity-induced hypertension: role of sympathetic nervous system, leptin, and melanocortins","volume":"285","author":"Hall","year":"2010","journal-title":"J. Biol. Chem."},{"issue":"Pt B","key":"10.1016\/j.lfs.2016.02.093_bb0900","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.physbeh.2015.08.010","article-title":"Sex differences in body fluid homeostasis: sex chromosome complement influences on bradycardic baroreflex response and sodium depletion induced neural activity","volume":"152","author":"Vivas","year":"2015","journal-title":"Physiol. Behav."},{"issue":"2","key":"10.1016\/j.lfs.2016.02.093_bb0905","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1161\/HYPERTENSIONAHA.115.05303","article-title":"Angiotensin II type 2 receptor- and acetylcholine-mediated relaxation: essential contribution of female sex hormones and chromosomes","volume":"66","author":"Pessoa","year":"2015","journal-title":"Hypertension"},{"issue":"6","key":"10.1016\/j.lfs.2016.02.093_bb0910","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1097\/00004872-200406000-00023","article-title":"Gender difference in the response to an angiotensin-converting enzyme inhibitor and a diuretic in hypertensive patients of African descent","volume":"22","author":"Falconnet","year":"2004","journal-title":"J. Hypertens."},{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0915","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1111\/j.1524-6175.2007.07195.x","article-title":"Predictors of blood pressure response to angiotensin receptor blocker\/diuretic combination therapy: a secondary analysis of the irbesartan\/hydrochlorothiazide blood pressure reductions in diverse patient populations (INCLUSIVE) study","volume":"10","author":"Saunders","year":"2008","journal-title":"J. Clin. Hypertens. (Greenwich)"},{"issue":"11","key":"10.1016\/j.lfs.2016.02.093_bb0920","doi-asserted-by":"crossref","first-page":"2163","DOI":"10.1097\/01.hjh.0000249692.96488.46","article-title":"Outcomes in subgroups of hypertensive patients treated with regimens based on valsartan and amlodipine: an analysis of findings from the VALUE trial","volume":"24","author":"Zanchetti","year":"2006","journal-title":"J. Hypertens."},{"issue":"1","key":"10.1016\/j.lfs.2016.02.093_bb0925","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1038\/ajh.2007.24","article-title":"Predictors of blood pressure response to the angiotensin receptor blocker candesartan in essential hypertension","volume":"21","author":"Canzanello","year":"2008","journal-title":"Am. J. Hypertens."}],"container-title":["Life Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320516301436?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0024320516301436?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T16:21:51Z","timestamp":1748794911000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0024320516301436"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8]]},"references-count":185,"alternative-id":["S0024320516301436"],"URL":"https:\/\/doi.org\/10.1016\/j.lfs.2016.02.093","relation":{},"ISSN":["0024-3205"],"issn-type":[{"value":"0024-3205","type":"print"}],"subject":[],"published":{"date-parts":[[2016,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Role of the endothelin system in sexual dimorphism in cardiovascular and renal diseases","name":"articletitle","label":"Article Title"},{"value":"Life Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.lfs.2016.02.093","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}